Ngaba ugqirha wakho ukuxelele ukuba wenze uvavanyo lwe-G6PD? Okanye ujonge olu vavanyo kuba umntwana wakho omncinci une-jaundice kwaye ayizukuphela? Mhlawumbi usandul' ukuva igama elithi G6PD. Kuqhelekile ukuba woyike kancinci kuba igama lingaqhelekanga. Kodwa ungoyiki nantoni na. Namhlanje, siza kuthetha ngolu vavanyo lwe-G6PD kunye nokusilela kwe-G6PD okubangela oku ngendlela elula kakhulu onokuyiqonda.
Masiqale sibone, yintoni i-G6PD?
Kulungile, masiqale ngomzekelo olula kakhulu. Khawucinge ukuba iiseli ezibomvu zegazi emzimbeni wakho zifana nezindlu ezincinci. Ngaphakathi kwezi zindlu, umsebenzi obalulekileyo wokuhambisa ioksijini uyenzeka. Ngoku, kufuneka kubekho 'umlindi' wokukhusela ezi zindlu, ukuzigcina zomelele. Ngoko ke, kukho umsebenzi okhethekileyo obizwa ngokuba yi-G6PD okhusela izindlu zethu ezibizwa ngokuba ziiseli ezibomvu zegazi kwaye uzinceda ukuba zihlale ziphilile.
Ngokwezonyango, i-G6PD ligama elifutshane le-enzyme i-glucose-6-phosphate dehydrogenase . I-enzyme yiproteni enceda imizimba yethu ukuba iqhube iinkqubo ezahlukeneyo zeekhemikhali ngokufanelekileyo. Umsebenzi ophambili wale enzyme ye-G6PD kukukhusela iiseli zethu ezibomvu zegazi kwiikhemikhali ezithile (ezibizwa ngokuba ziintlobo zeoksijini ezisebenzayo) ezinokuzonakalisa.
Ngoko ke, ukuba umzimba womntu awunalo ngokwaneleyo eli gada, okanye i-enzyme ebizwa ngokuba yi-G6PD, siyibiza ngokuba yi -G6PD deficiency . Oku kuyimfuza, oko kuthetha ukuba kuzuzwe njengelifa. Umntu onesi siphene unenani elibuthathaka kancinci leeseli ezibomvu zegazi. Kufana nendlu engenamlindi. Emva koko, xa evezwa kwizinto ezithile, ezi seli zibomvu zegazi ziqala ukuwohloka kwaye zitshatyalaliswe ngokukhawuleza. Xa umzimba ungakwazi ukwenza iiseli ezibomvu zegazi ezintsha kwaye ezindala zitshatyalaliswa ngokukhawuleza, kwenzeka imeko ebizwa ngokuba yi-anemia. Xa iiseli ezibomvu zegazi ziqhekeka ngale ndlela, siyibiza ngokuba yi -hemolytic anemia .
Ngoko ke, kufuneka ulwenze nini uvavanyo lwe-G6PD?
Ixesha elininzi, abantu abanesifo se-G6PD ababonisi zimpawu. Baphila ubomi obuqhelekileyo. Nangona kunjalo, kuphela xa bevezwa 'zizinto' ezithile apho imeko ye-hemolytic anemia esithethe ngayo ngaphambili iyenzeka kwaye iimpawu zivele.
Ngoku makhe sibone ukuba zeziphi ezi zinto zibangela ukuba kubekho iingxaki.
| Izinto ezibangela iimpawu | Ingcaciso elula malunga noku |
|---|---|
| Ezinye izifo | Uxinzelelo emzimbeni olubangelwa zizifo ezibangelwa ziibhaktheriya okanye iintsholongwane lunokukhawulezisa ukuqhekeka kweeseli ezibomvu zegazi. |
| Iimbotyi zeFava | Le yeyona nto ixhaphakileyo ebangela le meko. Abanye abantu banokuba neempawu zokutya iimbotyi ze-fava okanye ukuphefumla i-pollen yazo. Oku kukwabizwa ngokuba yi-'favism'. |
| Amanye amayeza | Nangona kunjalo, ayizizo zonke amayeza anokwenza imeko ibe mandundu, njengee-antibiotics ezithile, i-antimalarials, kunye ne-nonsteroidal anti-inflammatory drugs (NSAIDs). Ngoko ke, ukuba unesifo se-G6PD esinqongopheleyo, kubalulekile ukuxelela ugqirha wakho ngaphambi kokuba uthathe naliphi na iyeza. |
Ngoko ke, xa ujongene ne-trigger efana naleyo, unokuba neempawu ze-hemolytic anemia. Kulapho ugqirha angacebisa ukuba kwenziwe uvavanyo lwe-G6PD. Jonga ukuba ezi mpawu zivakala ziqhelekile na kuwe.
| Uphawu | Ithetha ntoni le nto? |
|---|---|
| Ukuquleka ngequbuliso (i-syncope) | Xa ingqondo ingafumani ioksijini eyaneleyo, ukungabikho zingqondweni kunokwenzeka. |
| Ndiziva ndidiniwe kakhulu (Ndidinwe kakhulu) | Xa iiseli ezibomvu zegazi ezithwala ioksijini emzimbeni wonke zincipha, usenokuziva udiniwe kakhulu ukuba ungenza nemisebenzi eqhelekileyo. |
| Ukuziva ngathi intliziyo yakho ibetha ngokukhawuleza | Intliziyo kufuneka isebenze nzima ukuze ipompe igazi ngokukhawuleza kwaye inike umzimba ioksijini efunekayo. |
| Ubunzima bokuphefumla (ukuphelelwa ngamandla) | Xa amanqanaba eoksijini egazini ehla, usenokuziva uphelelwa ngumphefumlo uze uzive utyhafile. |
| Umchamo obomvu okanye omdaka | Xa inani elikhulu leeseli ezibomvu zegazi liqhekeka, umxholo wazo uphuma emchameni, nto leyo ebangela ukuba umchamo utshintshe umbala. |
| Ulusu olukhanyayo | Xa ukuhamba kwegazi kuncipha, ulusu lulahlekelwa ngumbala walo opinki luze lube mhlophe. |
| Ukutyheli kolusu namehlo (i-jaundice) | Xa iiseli ezibomvu zegazi ziqhekeka, into etyheli ebizwa ngokuba yi-bilirubin iqokelelana emzimbeni. Yiyo le nto ibangela ukuba ulusu kunye namhlophe emehlweni ajike abe tyheli. |
Kutheni kufuneka uvavanyo lwe-G6PD kwiintsana ezincinci?
I-jaundice ixhaphake kakhulu kwiintsana ezisandul’ ukuzalwa. Uninzi lwexesha, iya kuphela yodwa kwiintsuku ezimbalwa ukuya kwiiveki ezimbini. Nangona kunjalo, ukuba ezinye iintsana zine-jaundice kangangeeveki ezingaphezu kwezimbini kwaye kungekho sizathu sicacileyo sifumanekayo, ugqirha wakho unokucebisa uvavanyo lwe-G6PD.
Ukongeza, ukuba uyazi ukuba kukho umntu kusapho lwakho onesifo se-G6PD, kungcono ukuba olu vavanyo lwenziwe emva kokuba umntwana ezelwe. Ngale ndlela, unokukwazi oku kwangaphambili kwaye uthathe amanyathelo okhuseleko.
Kuqheleke kangakanani ukunqongophala kwe-G6PD?
Esi sisifo esixhaphakileyo emhlabeni. Kukholelwa ukuba abantu abangaphezu kwezigidi ezingama-400 kwihlabathi liphela banaso esi sifo. Nangona kunjalo, njengoko besitshilo ngaphambili, uninzi lwaba bantu aluyi kuba nazimpawu ebomini babo bonke.
Ukunqongophala kweempawu ze-G6PD kuxhaphake kakhulu kumadoda kunakwabasetyhini, kwaye kuxhaphake kakhulu kubantu baseAsia, eAfrika, okanye baseMeditera.
Lwenziwa njani uvavanyo lwe-G6PD?
Olu luvavanyo lwegazi oluqhelekileyo nolulula kakhulu. Akukho nto yokoyika nangayiphi na indlela. Kuthatha ngaphantsi kwemizuzu emihlanu.
- Inaliti encinci ifakwa emthanjeni osengalweni yesigulane kwaye kuthathwa isampuli yegazi.
- Emva koko iqhekeza liyasuswa kwaye kufakwa iplasta encinci.
Abanye abantu banoloyiko oluncinci lweenaliti (oku kubizwa ngokuba yi-trypanophobia). Ukuba unolu loyiko, xelela umongikazi otsala igazi lakho. Baza kukunceda. Ungajonga kude, uphefumle kancinci, okanye ube nomhlobo okanye ilungu losapho kunye nawe ngexesha lokutsalwa kwegazi.
Indlela yokwenza olu vavanyo kubantwana abancinci
Ngenxa yokuba kunzima ukufumana igazi engalweni yomntwana, kuthathwa isampuli yegazi esithendeni senyawo lakhe. Ngononophelo olukhulu, kusetyenziswa inaliti encinci ukugqobhoza indawo encinci esithendeni kwaye kuqokelelwe amathontsi ambalwa egazi. Emva koko kufakwa ibhandishi encinci kuloo ndawo. Umntwana usenokuva imvakalelo yokuluma kancinci, kodwa oku kuya kuphela ngokukhawuleza. Kunokubakho ukukrweleka okuncinci, kodwa oku kuya kuphola emva kosuku okanye ezimbini.
Ngaba kufuneka ndilungiselele ngaphambi kovavanyo?
Le yingxaki ebaluleke kakhulu. Ewe, kukho izinto ekufuneka uzilumkele.
- Xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini kunye nezongezo).
- Amanye amayeza nokutya kunokuchaphazela iziphumo zolu vavanyo. Ngoko ke ugqirha wakho angakuxelela ukuba ungatyi iimbotyi zefava okanye uyeke ukuthatha amayeza athile aqulethe i-sulfa kangangeentsuku ezimbalwa.
- Ngokwesiqhelo, ukuzila ukutya akufuneki ngaphambi kolu vavanyo.
Nantsi into ebaluleke kakhulu: Ukuba uneempawu ezisebenzayo ze-hemolytic anemia (umz., i-jaundice, ukudinwa) ngomhla owenza ngawo uvavanyo lwakho, ugqirha wakho unokulihlehlisa uvavanyo kude kube lolunye usuku. Oku kungenxa yokuba xa uneempawu, iiseli zegazi ezibomvu ezingenayo i-G6PD zihlala zitshatyalaliswa. Oko kushiya kuphela iiseli eziphilileyo egazini lakho. Ukuba wenza uvavanyo ngelo xesha, unokufumana iziphumo ezingezizo ezithi inqanaba lakho le-G6PD liqhelekile.
Ngaba kukho naziphi na iingozi ngolu vavanyo?
Olu luvavanyo olungenamngcipheko uphezulu kakhulu. Njengalo naluphi na olunye uvavanyo lwegazi,
- Inxeba elincinci apho inaliti yayifakwe khona.
- Inxeba elincinci
- Kunqabile kakhulu, ukopha okanye usulelo
Izinto ezinjalo zinokwenzeka, kodwa zihlala ziphila ngokupheleleyo emva kosuku olunye okanye ezimbini.
Ingxelo yovavanyo ithini?
Ukuba ingxelo yakho ibonisa ukuba inqanaba lakho le-G6PD liphantsi, oko kuthetha ukuba unesiphene se-G6PD. Kodwa oko akuthethi ukuba ngokuqinisekileyo une-hemolytic anemia. Abantu abaninzi baphila ngaphandle kweempawu. Eyona nto ibalulekileyo kukuhlala kude nezinto ezibangela iimpawu.
Abanye abafazi banokuba namanqanaba e-G6PD aphantsi kancinci kunesiqhelo. Oku kuthetha ukuba 'bathwali' bokunqongophala kwe-G6PD. Ngamafutshane, banejini yokungabikho kwe-G6PD kunye nejini ephilileyo kwiijini zabo. Aba bantu badla ngokungabi nazimpawu. Kodwa banokudlulisela ijini kubantwana babo.
Ndifanele ndibonane nogqirha nini?
Abantu abaninzi abanesifo se-G6PD baphila ngempumelelo ngaphandle kwezinto ezibangela esi sifo. Kodwa ukuba ubonakalisa iimpawu ze-hemolytic anemia, ezo mpawu ziquka:
- Ukuba kunzima kakhulu ukwenza imisebenzi yakho yemihla ngemihla
- Ukuba ihlala ngaphezulu kweeyure ezingama-24-48
Bona ugqirha wakho ngoko nangoko. Kwiimeko ezinzima kakhulu, unokufuna ukulaliswa esibhedlele ukuze ufumane unyango. Kwimeko engxamisekileyo enjalo, kufuneka uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane.
Umyalezo Wokuya Ekhaya
- I-G6PD yi-enzyme ebalulekileyo ekhusela iiseli zethu ezibomvu zegazi.
- Ukunqongophala kwale enzyme (ukungabikho kwe-G6PD) yimeko yemfuza.
- Abantu abaninzi banale meko kodwa ababonisi zimpawu.
- Ukuchatshazelwa zizinto ezibangela oku njengeembotyi ze-fava, amayeza athile, kunye nosulelo kunokubangela ukuba iiseli ezibomvu zegazi ziqhekeke, nto leyo ebangela i-hemolytic anemia.
- Uvavanyo lwe-G6PD luvavanyo lwegazi olulula olwenziwayo ukuze kufunyanwe le meko.
- Ukuba unesiphene se-G6PD, eyona nto ibalulekileyo kukwazi ukuba zeziphi izinto ezikubangelayo uze uziphephe.
- Eyona nto ibalulekileyo: Ukuba unesiphene se-G6PD, qiniseka ukuba wazise ugqirha wakho ngaphambi kokuba unike amayeza amatsha.
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