Ngaba uyayazi iGiant Cell Tumor (GCT)? Makhe sithethe ngayo!

Ngaba wakha waziva iintlungu ezibuhlungu, ukudumba okuncinci, okanye iqhuma esandleni sakho, ingakumbi edolweni, esinqeni, egxalabeni, okanye esihlahleni? Ukuba kunjalo, licebo elihle ukuba ukhathazeke kancinci. Kuba isenokuba luphawu lwemeko esiza kuthetha ngayo namhlanje ebizwa ngokuba yi-'Giant Cell Tumor (GCT)'. Ungakhathazeki, siza kuthetha ngayo ngokweenkcukacha.

Yintoni kanye kanye iGiant Cell Tumor (GCT)?

Ngamafutshane, i-"Giant Cell Tumor (GCT)" yi -tumor engenamhlaza (kwaye idla ngokuba yi-benign) . Ihlala ikhula eziphelweni zamathambo amade emzimbeni wakho. Ngokukodwa, ifumaneka kakhulu ezantsi kwethambo lakho lethanga elithi "femur" okanye phezulu kwethambo lakho le-shin elithi "tibia", elijikeleze idolo . Nangona kunjalo, inokwenzeka nakwiindawo ezifana nesinqe, igxalaba, isandla, kunye nethambo lomsila. Ezi zikwabizwa ngokuba yi-"Osteoclastomas".

Le meko ibizwa ngokuba yi-`(GCT)` ayiqhelekanga kakhulu . Iyenzeka kumntu omnye ukuya kwabababini kwikhulu lamawaka ngalinye. Nangona kunjalo, phakathi kweethumba ezingezizo ezomhlaza eziqala emathanjeni, i-`(GCT)` ibandakanya phakathi kwe-15% kunye ne-21% yazo zonke iimeko.

Ngamanye amaxesha la mathumba amakhulu eeseli awaphuhli emathanjeni, kodwa aphuhli kwizicubu ezithambileyo ezijikeleze amalungu. Emva koko abizwa ngokuba yi-"Tenosynovial giant cell tumors".

Into ebalulekileyo kukuba nangona ezi `(Giant Cell Tumors)` zingengomhlaza, zinokukhula ngokukhawuleza kwaye zonakalise izicwili eziphilileyo ezijikeleze . Kwakhona, zinethuba elikhulu lokuba `(ziphinde zibuye)` nasemva konyango. Yiyo loo nto kubalulekile ukubona ugqirha ngokukhawuleza ukuba ubona naziphi na iimpawu zethumba elinje.

Zithini iimpawu zoku? Jonga ukuba nawe unazo ezi...

Uphawu oluphambili noluqhelekileyo lwe-giant cell tumor (GCT) yintlungu . Nangona intlungu isenokuba ncinci ekuqaleni, iyanda njengoko i-tumor ikhula. Khawuthelekelele, uvuka kusasa uze uve intlungu encinci kufutshane nedolo lakho. Ekuqaleni, awuyinaki. Kodwa emva kwexesha elithile, intlungu iyanda, kwaye xa uyichukumisa, ivakala ngathi yiqhuma elincinci. Kulapho ke uqalisa ukoyika kancinci, akunjalo?

Kukho nezinye iimpawu ezininzi:

• Iqhuma okanye ukudumba okubonakalayo esandleni kubonakala kuloo ndawo.
• Ukungakwazi ukuhambisa ilungu ngokufanelekileyo apho kukho ithumba kuthetha ukuba intshukumo yelungu incinci.
• Intlungu yamalungu , ingakumbi xa kushukunyiswa amalungu.
• Ukudumba .
• Ithumba linokwenza amathambo abe buthathaka kwaye libangele ukwaphuka .

Ukuba unenye okanye ngaphezulu kwezi mpawu, nceda ucele ingcebiso kugqirha.

Kutheni kusenzeka into efana nale? Yintoni unobangela?

Enyanisweni, abaphandi bezonyango abakayazi kakuhle into ebangela ii-giant cell tumors. Nangona kunjalo, abanye abantu abanale meko bafunyenwe benotshintsho oluthile (iinguqu) kwiijini zabo. Nangona kunjalo, okwangoku kukholelwa ukuba oku akuyonto izuzwe njengelifa, okanye into ebangelwa yindawo ohlala kuyo okanye indlela ophila ngayo .

Ngaba kukho naziphi na izinto ezinokubangela umngcipheko?

Ewe, phantsi kweemeko ezithile amathuba okuphuhlisa le `(GCT)` anokwanda kancinci:

• Ukuba unesifo esibizwa ngokuba yi-`(Hyperparathyroidism)` (apho uvelisa i-parathyroid hormone eninzi kakhulu),`(GCT)` inokukhula kwiindawo ezahlukeneyo emzimbeni wakho.
• Kunqabile kakhulu ukuba abantu abanesifo samathambo esibizwa ngokuba yi-"Paget's disease of the bone" nabo banokuba nezi tumors ezinkulu zeeseli.

Ngaba oku kungaba yingozi? Zithini iingxaki?

Nangona ezi thumba zingengomhlaza, kunqabile, oko kukuthi, kunqabile kakhulu, ezi thumba zinkulu zeeseli zinokusasazeka ziye emiphungeni . Nangona kunjalo, akufani nokusasazeka komhlaza, kwaye nokuba usasazeka ngale ndlela, awusoloko usongela ubomi.

Okungaqhelekanga nangakumbi, malunga ne-4% yabantu abane-GCT, la mathumba anokuba ngumhlaza (ayingozi) . Ke ngoko, ugqirha wakho uya kujonga imeko yakho rhoqo ukuze abone ukuba kukho naluphi na utshintsho oluyingozi kwithumba. Yingakho kubalulekile ukubona ugqirha wakho rhoqo kwaye ufumane ingcebiso.

Oogqirha bayifumana njani le nto?

Ukuqinisekisa ukuba unayo na i-giant cell tumor (GCT) , kwenziwa i-biopsy . Oku kuquka ukuthatha isampuli encinci yezicubu ezivela kwi-tumor uze uyihlole phantsi kwe-microscope. Olu vavanyo lwenziwa yingcali yezifo, ugqirha ogxile kwizicubu. Uza kujonga ukuba iiseli "zii-giant cells," okanye zineempawu ze-GCT.

Ukongeza, iimvavanyo zomfanekiso ezifana nezi zinokwenziwa ukujonga ithumba elingaphakathi emzimbeni wakho:

• Ii-X-reyi : Jonga imeko yamathambo.
• I-CT scan : Jonga ubungakanani kunye nokuma kwethumba ngokweenkcukacha.
• I-MRI : Ihlola izicubu ezithambileyo, umongo wethambo, njl.
• Ukuskena amathambo : Jonga iingxaki kwezinye iindawo emathanjeni.
• Iiskeni zePET : Ukubona ukuba kukho na iimpawu zokuba ithumba liyajika libe ngumhlaza.

Zonke ezi mvavanyo zenziwa ukuze kufunyanwe ukuqonda ngokupheleleyo imeko yakho kunye nokuchonga unyango olungcono.

Kulungile, ngoku zeziphi iindlela zonyango zoku?

Ii-giant cell tumors zihlala zinyangwa ngotyando . Ugqirha uyasusa i-tumor kwithambo (i-curettage). Emva koko, i-bone graft ibekwa kwindawo engenanto.Ithambo liqiniswa ngokuxhunyelelwa (iqhekeza lethambo elithathwe kwenye indawo okanye kwinto eyenziweyo). Ngamanye amaxesha, ukuba ithumba likhulu kakhulu, lonke ithambo eliqulathe ithumba kunokufuneka lisuswe. Kwimeko enjalo, ilungu lokwenziwa okanye ithambo elithi "prosthesis" linokufakwa endaweni yalo.

Nangona kunjalo, kwiimeko apho utyando lungenakuyisusa ngokupheleleyo ithumba, okanye ukuba utyando luyingozi, kukho unyango olungelulo utyando. Olu luquka:

• I-Denosumab (i-Denosumab - i-Xgeva®) : Olu luhlobo lonyango olubizwa ngokuba yi-monoclonal antibody. Lunciphisa ithumba kwaye luqinise ithambo elijikelezileyo.
• Ukufakwa kwegazi emzimbeni : Oku kuquka ukuvala imithambo yegazi ehambisa igazi kwithumba. Oku kuyayithintela ithumba ukuba lingafumani igazi kwaye kubangela ukuba life kancinci kancinci.
• Unyango lokukhupha isisu : Oku kusebenzisa into efana namandla e-microwave ukutshabalalisa ithumba.
• Unyango lwemitha : Oku kusebenzisa ii-X-ray ezinamandla aphezulu ukunciphisa ithumba nokutshabalalisa iiseli.

Ugqirha wakho uya kugqiba ukuba loluphi unyango olulungele wena.

Kuthatha ixesha elingakanani ukuchacha emva konyango?

Ixesha eliza kuthatha ukuze uphile lixhomekeke kunyango olufumeneyo. Ukuba utyando, kuya kufuneka unxibe amabhandeji kangangeeveki eziliqela ngelixa inxeba liphola. Kusenokufuneka usebenzise iintonga ngelo xesha. Ukuba unesixhobo sokufakelwa, kuya kufuneka usebenzisane nogqirha wezonyango ukuze uqhele.

Ugqirha wakho uza kukuchazela konke oku, ngoko ke akukho nto inokubangela ukuba ukhathazeke.

Ngaba akukho ndlela yokuthintela oku ukuba kungenzeki? Iyintoni inzuzo yokwazi kwangaphambili?

Ekubeni imbangela echanekileyo yee-giant cell tumors ingaziwa, okwangoku akukho ndlela yokuthintela ukuba zingaphuhli . Nangona kunjalo, eyona nto ingcono onokuyenza kukufuna ingcebiso kagqirha kwangoko nje ukuba uqaphela iimpawu . Ukuba ubona iintlungu, ukudumba, okanye iqhuma kwelinye lamathambo okanye amalungu akho, musa ukulibazisa kwaye ubone ugqirha ngoko nangoko. Ukuba ii-tumors ezifana ne-`(GCT)` zifunyenwe kwangethuba, kulula ukuzinyanga kwaye azinazo iingxaki ezininzi.

Ukuba kunokwenzeka, kungcono ukubona ugqirha ogxile kumhlaza onxulumene namathambo, ingcali yomhlaza wamathambo .

Ngoko ke uphila njani nale meko? Ngaba kufuneka uye kugqirha rhoqo?

Ii-giant cell tumors azifane zibe yingozi ebomini. Nangona kunjalo, zingonakalisa amathambo akho kunye nezicubu ezikungqongileyo, yiyo loo nto unyango lwasekuqaleni lubalulekile.

Iindaba ezimnandi zezokuba ukuba zonke iindawo zethumba zisusiwe ngotyando, le meko inokunyangeka ngokupheleleyo. Nangona kunjalo, i-GCT luhlobo lwethumba oluqinileyo kwaye lunokukhula kwakhona .

Emva konyango, ugqirha wakho uza kukujonga rhoqo ukuze afumane amadinga okulandela . Oku kukujonga ukuba ithumba libuyile na. Amaxesha amaninzi, la mathumba abuya kwiminyaka emibini ukuya kwemihlanu yokuqala emva kotyando. Nangona kunjalo, unokufuna ukuvavanywa rhoqo ubomi bakho bonke. Ugqirha wakho uza kukuxelela ukuba kufuneka uye kangaphi kwezi zilingo.

Kufuneka udibane nogqirha kwakhona nini?

Ukuba uneempawu zokuba ithumba lakho elikhulu liyabuya, bonana nogqirha wakho ngoko nangoko. Qaphela nayiphi na intlungu entsha okanye ukudumba kwamathambo okanye amalungu. Nokuba ugqirha wakho uhlola rhoqo, ukuba ubona naluphi na utshintsho, kungcono ufowunele ugqirha wakho ngoko nangoko ngaphandle kokulinda idinga lakho elilandelayo.

Ungathanda ukubuza ntoni ugqirha?

Xa ubona ugqirha, kungcono ukubuza le mibuzo:

• Ingaba eli thumba linamandla kangakanani?
• Ziziphi iindlela zonyango endinazo?
• Ziziphi iingenelo kunye neengozi ezinxulumene nonyango ngalunye?
• Lingakanani ithuba lokuba eli thumba likhulu leseli liphinde libuye emva konyango?
• Kuza kufuneka ndize kangaphi kwixesha lokulandela ?

Ukwazi iimpendulo zale mibuzo kuya kukunceda uyiqonde ngcono imeko kwaye kube lula ukumelana nonyango.

Ngoko ke, zeziphi izinto ezibalulekileyo ekufuneka sizikhumbule kweli bali?

Ukuba nje i-giant cell tumor (GCT) "ayinabungozi" akuthethi ukuba ayizukubangela monakalo. Ukuba ayinyangwa, ezi GCTs zinokubangela umonakalo omkhulu emathanjeni akho.

Eyona nto ingcono kukuba ungazisusa ngotyando lokususa zonke iimpawu zethumba. Nangona kunjalo, ezi `(GCT)` zilukhuni kancinci kwaye zinokukhula kwakhona. Yiyo loo nto ugqirha wakho eza kukujonga ngokusondeleyo emva konyango. Ukususa ithumba ngelixa lisencinci kunokuthintela umonakalo wexesha elide emathanjeni.

Ngoko ke, ukuba unale mpawu, ungathandabuzi ukubona ugqirha kwaye ufumane ingcebiso. Unyango lwangethuba yeyona ndlela ilungileyo yokuphila ubomi obusempilweni!

I- Giant Cell Tumor, i-GCT, i-osteoclastoma, i-benign tumor, i-bone tumor, iintlungu zethambo, unyango lwe-tumor