Usenokuba ukhe wabona nebali leendaba lakutshanje malunga neHuman Growth Hormone, okanye iHGH. Ukuva ukuba le hormone inokubangela isifo se-Alzheimer kumele ukuba kukwenze woyika kwaye waxhalaba kancinci, akunjalo? Olu loyiko lunokuba lukhulu ngakumbi ukuba ugqirha ukunike olu nyango lwehomoni wena okanye umntwana wakho. Ngoko masithethe ngale nto ngokweenkcukacha namhlanje, yintoni inyaniso kweli bali, kwaye masiqonde ngokucacileyo ukuba kufuneka soyike okanye hayi.
Iqale njani le bali?
Eli bali livela ngequbuliso kuphando olwenziwe liqela labaphandi eBritane ngonyaka ka-2024. Bafumanise ukuba kudala, phakathi kowe-1959 nowe-1989, abantu abaliqela abafumana uhlobo oluthile lwe-HGH olunikwa abantwana abakhubazekileyo kamva baba nesifo se-Alzheimer.
Kodwa eyona nto ibalulekileyo apha luhlobo lwe-HGH olwalusetyenziswa ngelo xesha. Lubizwa ngokuba yi -cadaveric growth hormone . Ngamafutshane, ezo hormone zazithathwa emizimbeni yabantu abafileyo, ngakumbi kwi-pituitary gland esebuchotsheni. Cinga ngayo njengokuphatha omnye umntu ngenxalenye yomzimba wakhe.
Malunga nowe-1985, umntu owayethathe le hormone yakudala waba nesifo sengqondo esiyingozi esibizwa ngokuba yiCreutzfeldt-Jakob disease (CJD) . Sisifo esibangela ukulahleka kwenkumbulo okufana ne-Alzheimer's. Uvavanyo lwamva lwaqinisekisa ukuba esi sifo se-CJD sibangelwe sisiphene kwiihomoni ezithathwe kwabo bantu baswelekileyo. Ngesi siganeko, i-HGH kubantu abaswelekileyo yayekwa ngokupheleleyo kwihlabathi liphela.
Uphando olutsha lufumanise kutshanje ukuba xa kuhlolwa ubuchopho babantu abaliqela kwiqela elinye abasweleke ngenxa ye-CJD, babunee-deposits zeproteni ebizwa ngokuba yi -beta-amyloid engqondweni yabo. Le yiproteni efanayo egcinwe kwiingqondo zabantu abanesifo se-Alzheimer. Uninzi lwaba bantu babeneempawu ze-Alzheimer besebancinci kakhulu, bekwiminyaka yabo yama-30 nama-40.
Ngoko ke olu phando lubonisa ukuba ungcoliseko oluthile kwi-HGH endala, eneminyaka emininzi ithathwe kubantu abafileyo lusenokuba lukhokelele ekubeni iiproteni ezinxulumene nesifo sika-Alzheimer zifunxwe emzimbeni.
Ngoko ke, ngaba i-HGH enikwe namhlanje iyingozi kangako?
Nantsi eyona nto ibalulekileyo ekufuneka uyiqonde ngokucacileyo. Hayi. I-HGH enikwa namhlanje ayiyongozi kangako.
Kangangamashumi eminyaka, oogqirha kwihlabathi liphela bebenika amayeza e-HGH asetyenzisiweyo . Oko kukuthi, i-hormone eveliswa kwilebhu ngendlela ecocekileyo kakhulu, ekhuselekileyo, neyokwenziwa. Ayinazo izicwili zomntu. Ke ngoko, akukho thuba lokuba i-CJD, okanye iproteni ye-Alzheimer, njengoko uphando oludala lubonisa, inokudluliselwa ukusuka komnye umntu ukuya komnye.
Masibone ngokucacileyo umahluko phakathi kwezi ndlela zimbini.
| Uphawu | I-HGH endala (iCadaveric - ngaphambi kowe-1989) | I-HGH yanamhlanje (Eyenziweyo - Ekhoyo) |
|---|---|---|
| Indlela yokuyifumana | Ifunyanwa kwi-pituitary glands yabantu abafileyo. | Yenziwe ngokwenziwa nangokucocekileyo kwilebhu. |
| Ukhuseleko kunye nomngcipheko | Kwakukho umngcipheko wokudlulisela iiproteni ezinxulumene nezifo ezifana ne-CJD kunye ne-Alzheimer's. | Ngenxa yokuba ayinazo izicwili zomntu , akukho mngcipheko wokosuleleka okunjalo. |
| Ukusetyenziswa kwangoku | Akukasetyenziswa naphi na emhlabeni kangangeminyaka emininzi ngoku. | Olu lolona hlobo lodwa lwe-HGH olusetyenziswa ngoku kwimiyalelo kagqirha. |
Masifunde nangotshintsho lwendalo kumanqanaba e-HGH.
Kukho izifundo ezibonisa ukuba amanqanaba aphezulu okanye aphantsi e-HGH emzimbeni (umz., iimeko ezifana ne -acromegaly ) anokuba nemiphumo ethile kwinkumbulo kamva ebomini. Kodwa oko kwahlukile ngokupheleleyo ekuthatheni idosi echanekileyo ye-HGH njengonyango phantsi kweliso likagqirha. Enyanisweni, ukuba umntu onesifo se-HGH akanyangwa kakuhle, ukwehla kwengqondo kunokwenzeka.
Ngaba isifo sika-Alzheimer siyasuleleka?
Oku kukwayingxaki kubantu abaninzi. Hayi. Isifo sika-Alzheimer asisuleli. Awusifumani esi sifo kuba nje unyamekele umntu one-Alzheimer's, ubukunye naye, usebenzise into ayisebenzisileyo. Asisuleli njengomkhuhlane.
Okwenzekileyo kweso siganeko sidala se-HGH kukufakwa kwezinto eziphilayo ezingcolisiweyo emzimbeni. Loo nto ingaqhelekanga kwaye yinto engasasebenziyo.
Izinto ezibangela umngcipheko wokwenene wokufumana isifo se-Alzheimer zezi:
- Ukwaluphala: Umngcipheko uyanda ngokuhamba kweminyaka.
- Imbali yosapho: Umngcipheko uphezulu ukuba kukho umntu kusapho okhe waba nayo.
- Ukulimala kakhulu entloko.
- Ezinye iimeko zonyango: uxinzelelo lwegazi oluphezulu, isifo seswekile, i-cholesterol ephezulu.
- Indlela yokuphila: Ukutya okungenampilo, ukutyeba kakhulu, ukungazilolongi, nokungalali ngokwaneleyo.
Ngoko ke kufuneka ndiyeke unyango lwe-HGH?
Hayi, akunjalo. Ukuba wena okanye umntwana wakho ufumana unyango lwe-HGH ngokucetyiswa ngugqirha, musani ukoyika kwaye niyeke unyango ngoko nangoko emva kokubona iindaba ezinje. Ukwenza njalo kuya kwenza umonakalo omkhulu kunokuba kuncede.
Kule mihla, unyango lwe-HGH lunikezelwa ngezizathu zonyango ezicacileyo. Umzekelo:
- Ukungabikho kwehomoni yokukhula
- Ukufiphala okubangelwa ziimeko zemfuza ezifana ne -Turner syndrome kunye ne-Prader-Willi syndrome .
- Ukuphelelwa ngamandla kwemisipha okubangelwa lusulelo lwe-HIV.
- Isifo samathumbu amafutshane.
Unyango lwe-HGH lunyango olubaluleke kakhulu nolukhuselekileyo kubantu abanezi meko. Ke ngoko, eyona nto ingcono onokuyenza kukuxoxa ngokukhululekileyo nangayiphi na intandabuzo okanye uloyiko onalo nogqirha wakho onyangayo. Uza kukuchazela oku ngokweenkcukacha aze athomalalise uloyiko lwakho.
Ukuba wena okanye umntwana wakho ninikwe unyango lwe-HGH ngugqirha, qiniseka ukuba uthetha naye ngaphambi kokuba uyeke ukulusebenzisa. I-HGH yokwenziwa esetyenziswayo ngoku ayibeki mngcipheko we-Alzheimer's.
Umyalezo Wokuya Ekhaya
- Kutshanje, kukho intetho malunga nohlobo lwe-HGH oluvela kubantu abafileyo olwalusetyenziswa kwiminyaka emininzi eyadlulayo (1959-1989). Alusasetyenziswa naphi na.
- I-HGH esetyenziswayo namhlanje yi-hormone ekhuselekileyo kakhulu eveliswa kwilebhu (eyenziweyo). Ayinawo umngcipheko wokudlulisela izifo ezifana ne-Alzheimer's okanye i-CJD.
- Isifo sika-Alzheimer asisosifo esidluliselwa ukusuka komnye umntu ukuya komnye kubomi bemihla ngemihla.
- Ukuba ugqirha wakho ucebise unyango lwe-HGH, qhubeka nalo ngaphandle koloyiko. Ukuba unamathandabuzo, qiniseka ukuba uthetha nogqirha wakho ngaphambi kokuba uyeke unyango.
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