Ingaba unenani elandayo lee-eosinophils, uhlobo lweeseli ezimhlophe zegazi, emzimbeni wakho? Masithethe nge-Hypereosinophilic Syndrome!

Ngaba ngamanye amaxesha ukhe uzive ngathi kukho into engalunganga emzimbeni wakho, ukuba uhlala uneengxaki, kodwa awukwazi ukuqonda ukuba yintoni kanye kanye? Kukho ezinye izifo ezingaqhelekanga kwaye zinzima kancinci. Namhlanje siza kuthetha ngesinye sezifo ezinjalo. Kule nto, kukho ukwanda okukhulu kwenani lee -eosinophils, uhlobo olukhethekileyo lweeseli ezimhlophe zegazi emzimbeni wethu.

Yintoni i-Hypereosinophilic Syndrome?

Ngamafutshane, i-Hypereosinophilic Syndrome (HES) yimeko engaqhelekanga eyenzeka xa kukho ukwanda okukhulu kwenani lee-eosinophils , uhlobo lweeseli ezimhlophe zegazi emzimbeni wethu. Ngoku usenokuba uzibuza ukuba zeziphi ezi eosinophils.

Cinga ngayo njengenqaba. Kukho iintlobo ezahlukeneyo zamajoni okukhusela le nqaba. Ngokufanayo, kukho iintlobo ezahlukeneyo zeeseli ezimhlophe egazini lethu ezilwa neentsholongwane kwaye zisikhusele kwizifo. Ii-Eosinophils zelinye lamajoni akhethekileyo. Indima yazo ephambili kukulwa neentsholongwane ezingena emizimbeni yethu kunye nokusabela xa kuvela i-allergies.

Ngokwesiqhelo, ii-eosinophils zenza i-5% ukuya kwi-7% yeeseli ezimhlophe zegazi ezipheleleyo egazini lomntu ophilileyo. Oko kuthetha ukuba kukho phakathi kwe-100 kunye ne-500 yee-eosinophils kwi-microliter nganye yegazi. Nangona kunjalo, xa unento efana ne-allergy, ezi eosinophils zinokwanda kancinci. Siyibiza loo meko ngokuba yi-eosinophilia .

Nangona kunjalo, kwi-hypereosinophilic syndrome (HES), le meko ibizwa ngokuba yi-eosinophilia iba mandundu ngakumbi, kwaye ukuveliswa kwe-eosinophil kwenzeka ngesantya esiphezulu, nto leyo ebangela ukuba ezi seli ziqokeleleke kakhulu egazini nakwiithishu ezahlukeneyo zomzimba. Xa ii-eosinophils zisanda ngale ndlela, ezi seli ziqala ukonakalisa amalungu abalulekileyo afana nentliziyo yethu, imiphunga, ulusu, kunye nenkqubo yemithambo-luvo. Ukuba ayinyangwa ngokufanelekileyo, le meko inokuba yingozi ebomini. Kodwa iindaba ezimnandi zezokuba ukuba isifo sichongiwe kwangethuba kwaye unyango olufanelekileyo luqalwe, abantu abangaphezu kwama-80% abane-HES baphila kakuhle nokuba sele beneminyaka emihlanu emva kokuchongwa.

Ngubani ofumana i-hypereosinophilic syndrome (HES)?

Esi sifo sibizwa ngokuba yi-HES asiqhelekanga kangako. Ngoko ke kunzima koogqirha ukuxela ngokuthe ngqo ukuba bangaphi abantu abanale sifo. Nangona nabani na enokuba nesi sifo, sixhaphake kakhulu kubantu abaphakathi kweminyaka engama-20 ukuya kwengama-50 .

Yintoni ebangela i-hypereosinophilic syndrome (HES)?

Enyanisweni, kwiimeko ezininzi ze-HES, abaphandi abakafumani ngqo ukuba yintoni ebangela oku kunyuka ngequbuliso kwenani le-eosinophil. Nangona kunjalo, bachonge ezinye iimeko okanye izinto ezinokubangela oku:

• Izifo ze-Myeloproliferative: Ezi liqela lezifo ezibonakaliswa kukuveliswa kakhulu kweeseli zegazi kumongo wethu wamathambo. Ngamafutshane, kufana nokuba umongo wamathambo usebenza nzima kakhulu.
• Amanqanaba aphezulu e-Interleukin-5: Le yiproteni eveliswa ziiseli zethu ezimhlophe zegazi. Xa oku kusanda, ukuveliswa kwee-eosinophils kuyakhuthazwa.
• Ukungaqheleki kwemfuza okukhawulezisa ukukhula kweeseli: Ngamanye amaxesha, ezi seli zinokukhula ngendlela engalawulekiyo ngenxa yotshintsho kwiijini.

Zithini iimpawu ze-HES?

Uphawu oluqhelekileyo lwe-HES kukuqhambuka kwesikhumba okanye ukurhawuzelela. Ezinye iimpawu zixhomekeke ekubeni amanqanaba eosinophil aphezulu kangakanani emzimbeni.

Cinga ngale ndlela:

• Ukuba intliziyo ichaphazelekile: Usenokuba neempawu ezifana nokusilela kwentliziyo (imeko efana nokusilela kwentliziyo), iCardiomyopathy (ukuba buthathaka kwemisipha yentliziyo), iMyocarditis (ukudumba kwemisipha yentliziyo), okanye iPericardial Effusion (ukuqokelelana kolwelo olujikeleze intliziyo).
• Ukuba imiphunga iyachaphazeleka: Usenokuba nosulelo oluqhelekileyo lokuphefumla oluphezulu, olufana nomkhuhlane, ukukhwehlela, kunye nobunzima bokuphefumla.

Ukongeza, iimpawu eziqhelekileyo ezifana nokudinwa, umkhuhlane, iintlungu zomzimba, kunye nokuncipha komzimba nazo zinokubonakala.

Oogqirha bayixilonga njani i-hypereosinophilic syndrome (HES)?

Ukuchonga i-HES kunokuba yinkqubo enzima. Oogqirha badla ngokusebenzisa "inkqubo yokuphelisa isifo," oko kuthetha ukuqinisekisa ukuba akukho ezinye iimeko ezinokubangela oko.

Umzekelo, ukuba unezilonda zesikhumba ezihlala zikho nezirhawuzelelayo, ugqirha wakho unokuqala ajonge iimeko ezithile zesikhumba aze anike unyango lwazo.

Ukuba iimpawu zakho ziyaqhubeka emva kolu nyango, ugqirha wakho angenza uvavanyo lwegazi ukujonga amanqanaba aphezulu eosinophil egazini lakho. Ukuba iimpawu zakho zibonakala zinxulumene nengxaki yesibindi, kwaye emva kokufumanisa ezinye izizathu, ugqirha wakho angenza uvavanyo lwegazi lokusebenza kwesibindi . Ngamanye amaxesha, i-biopsy (ukuthatha isiqwenga sethishu) inokufuneka ukuqinisekisa ukuxilongwa kwe-HES.

Ngenxa yokuba esi sifo sithatha ixesha ukuxilonga, usenokuba ugule iinyanga, udiniwe, kwaye ungakwazi ukuqonda ukuba kwenzeka ntoni kanye kanye. Kodwa kubalulekile ukuba nomonde.

Oogqirha bayinyanga njani i-hypereosinophilic syndrome (HES)?

Eyona njongo iphambili yoogqirha kukunciphisa amanqanaba aphezulu e-eosinophils egazini nakwizicwili zakho. Ezona ndlela zonyango ziqhelekileyo ezisetyenziswayo ukufezekisa oku zezi:

• IiCorticosteroids: Ezi ziziyobisi ezinamandla zokulwa nokuvuvukala.
• Amayeza e-chemotherapy: Amayeza anikwa ukubulala iiseli zomhlaza. La mayeza asetyenziswa nakwiidosi eziphantsi ukulawula iiseli ze-eosinophil.

Ukongeza, amayeza ajoliswe kuwo afana ne -Imatinib kunye ne-monoclonal antibody ngamanye amaxesha ayasetyenziswa.

Ngaba i-hypereosinophilic syndrome (HES) ingathintelwa?

Ngelishwa, ekubeni unobangela ochanekileyo weemeko ezininzi ze-HES ungaziwa, kunzima ukutsho nantoni na ecacileyo malunga nendlela yokuyithintela.

Ukuba ndine-hypereosinophilic syndrome (HES), yintoni endimele ndiyilindele? (Inkqubela phambili yesi sifo)

Indlela eza kuhamba ngayo isifo sakho kwixesha elizayo, okanye "ukuxela kwangaphambili," kuxhomekeke kwimeko yakho ethile. Umzekelo, ukuba i-HES yakho ibangelwa yinto ethile, njengesifo somongo wethambo, ugqirha wakho uya kukunika unyango olujoliswe kweso sifo.

Nangona kunjalo, ukuba ugqirha wakho akakwazi ukubona unobangela wemeko yakho ye-HES, unyango luya kugxila ekulawuleni iimpawu zakho. Umzekelo, ukuba i-HES ichaphazela imiphunga yakho kwaye ufumana usulelo rhoqo, unyango luya kuzama ukulawula ezo sulelo.

Ngokubanzi, xa i-HES ifunyaniswa kwaye inyangwa ngokukhawuleza, kokukhona ingabi nangxaki ixesha elide.

Ndingayinyamekela njani impilo yam?

Njengoko besitshilo ngaphambili, oogqirha badla ngokunyanga i-HES nge-corticosteroids kunye ne-chemotherapy. Zombini ezi ndlela zonyango zinokuba nemiphumo emibi . Ngoko ke, thetha nogqirha wakho malunga nale miphumo emibi kunye nento onokuyenza ukunciphisa imiphumo yayo.

• Thatha amayeza akho ngexesha.
• Landela imiyalelo kagqirha.
• Yitya ukutya okunesondlo.
• Zama ukuphumla kangangoko unako.
• Hlala uqinile engqondweni.

Ndifanele ndimbone nini ugqirha wam?

Ukuba ufunyaniswe une-HES, kwaye iimpawu zakho ziyaqhubeka okanye ziya zisiba mandundu, bona ugqirha wakho ngoko nangoko. Kwakhona, qiniseka ukuba uyaya kwiindibano zakho ezicwangcisiweyo zekliniki.

Ndingaya nini kwiGumbi loNgxamiseko?

Siyazi ukuba imeko ebizwa ngokuba yi-hypereosinophilic syndrome (HES) inokuchaphazela amalungu ahlukeneyo omzimba, kuquka nentliziyo. Ngoko ke, ukuba intliziyo yakho ichaphazelekile yi-HES, kwaye ufumana iimpawu ezifana nentlungu yesifuba ngequbuliso, ukuqina kwesifuba, isicaphucaphu, kunye nokubila , kufuneka uye kwigumbi likaxakeka ngoko nangoko. Ezi zinokuba ziimpawu zokuhlaselwa yintliziyo.

Ndingayibuza yiphi imibuzo ugqirha wam?

Ngenxa yokuba i-HES yimeko engaqhelekanga, usenokuba nemibuzo emininzi ngayo. Nazi ezinye zemibuzo onokuzibuza ukuze uqalise:

• Gqirha, yintoni kanye kanye le Hypereosinophilic Syndrome?
• Kutheni oku kwenzeke kum?
• Ngaba oku kunganyangwa?
• Zeziphi iindlela zonyango ezikhoyo?
• Zithini iziphumo ebezingalindelekanga zonyango?
• Ngaba le meko ye-HES ingabuya kwakhona?
• Ndingaphiliswa ngokupheleleyo?

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

I-Hypereosinophilic syndrome (HES) yimeko engaqhelekanga kwaye ngamanye amaxesha kunzima ukuyifumanisa. Ukuba une-HES, kusenokwenzeka ukuba ubugula kangangeenyanga, uphethwe zizifo ezahlukeneyo, kwaye ungaziva kakuhle.

Kodwa iindaba ezimnandi zezokuba wakuba ufunyaniswe une-HES, kukho unyango olusebenzayo olufumanekayo. Kungathatha iinyanga ezininzi ukuba unyango lwakho lubonise iziphumo, ngoko zama ukuba nomonde. Kwakhona, ukuba unengxaki yokujongana nemingeni yesifo esihlala ixesha elide, thetha nogqirha wakho. Banokukuxelela ngeenkqubo kunye nezixhobo ezinokukunceda. Khumbula, awuwedwa!

Isifo seHypereosinophilic, i-HES, ii-Eosinophils, i-Eosinophilia, iiseli zegazi ezimhlophe, i-Eosinophilia, iimpawu, unyango