Sonke siyayazi inkxalabo kunye nokothuka okuvela kukuva kugqirha ukuba umntu esimthandayo unomhlaza osasazeke kuwo wonke umngxuma wesisu, oko kukuthi, ngaphakathi esiswini. Nangona kunjalo, ngokuhambela phambili kwesayensi yezonyango, ngoku kukho unyango olunokunika ithemba nakwiimeko ezinzima kangaka. Namhlanje, siza kuthetha ngonyango olulodwa olukhethekileyo noluphambili. Olu lubizwa ngokuba yi-HIPEC.
Kalula nje, yintoni i-HIPEC?
Igama elithi HIPEC limele iHyperthermic Intraperitoneal Chemotherapy . Nangona eli gama livakala liyinkimbinkimbi kancinci, okwenzekayo apha kulula kakhulu. Masiwahlule la magama size siwaqonde.
- I-Hyperthermic - ithetha "ukufudumeza" .
- I-Intraperitoneal - ithetha "ngaphakathi kwisisu." Ngamafutshane, i-peritoneal cavity yindawo engenanto ngaphakathi kwesisu sethu apho kukho amalungu anjengesibindi, isisu, kunye namathumbu.
- I-Chemotherapy - ibhekisa kumayeza anikwa ukutshabalalisa iiseli zomhlaza, njengoko sonke sisazi, "i-chemo".
I-HIPEC yindlela yonyango apho amayeza e-chemo ashushu afakwa ngqo kwisisu sesigulana emva kotyando, kwaye ingaphakathi lihlanjwe kakuhle, litshabalalisa iiseli zomhlaza. Njengokuba sihlamba isinki ngesepha, le ndlela isebenzisa i-chemo eshushu ukutshabalalisa neeseli zomhlaza ezincinci ezinokushiyeka ngaphakathi esiswini.
Loluphi uhlobo lomhlaza olu lufanelekileyo kulo?
Unyango lwe-HIPEC ludla ngokusetyenziselwa umhlaza osasazeke (owahlulwe yi-metastasized) ukuya esiswini usuka kwenye indawo emzimbeni. Lukwasetyenziswa nakwezinye umhlaza eziqala esiswini ngokwaso.
| Iintlobo zomhlaza ezicingelwayo kunyango lwe-HIPEC | |
|---|---|
| Umhlaza osasazeke kwisisu usuka kwezinye izitho: | |
| Umhlaza we-adrenal | Umhlaza wesihlomelo |
| Umhlaza weColoral | Umhlaza wesibindi |
| Umhlaza wesibeleko | Umhlaza wesisu |
| Umhlaza okhula ngaphakathi kwisisu: | |
| Umhlaza oyintloko we-peritoneal | I-mesothelioma ye-Peritoneal |
| I-Pseudomyxoma peritonei | |
Kubalulekile: Unyango lwe-HIPEC alunyangi ngokupheleleyo umhlaza. Nangona kunjalo, lunokunceda izigulane ziphile ixesha elide, zinciphise iimpawu, kwaye ziphile ubomi obungcono . Ugqirha wakho uza kukuchazela ngokweenkcukacha ukuba olu nyango lukulungele na kunye nezinto ezilungileyo nezingalunganga.
Ulungiselela njani olu tyando lukhulu?
Olu lunyango olunzima kakhulu nolunzima. Ngoko ke, kubaluleke kakhulu ukuzilungiselela kangangoko unako, emzimbeni nasengqondweni, ngaphambi kokuba kwenzeke. Iqela lakho lezonyango liza kukunceda ngale nto. Ezi zinto zilandelayo zinokuba zibalulekile ekulungiseleleni:
- Ukuba uyatshaya, yeka ngokupheleleyo .
- Ukuyeka ukusebenzisa utywala.
- Ukuzilolonga ngokuphefumla kusetyenziswa isixhobo esikhethekileyo (i-incentive spirometer) ukuqinisa imiphunga.
- Joyina iqela lenkxaso labaguli abanomhlaza okanye ucele uncedo kwingcali yezengqondo.
Injani yonke inkqubo yonyango?
I-HIPEC yinxalenye yesibini yenkqubo enamacandelo amabini. Yonke le nkqubo ingathatha phakathi kweeyure ezi-5 ukuya kwezili-10.
Inyathelo lokuqala: Utyando lweCytoreductive (CRS)
Inyathelo lokuqala lutyando. Ufakwa i-anesthesia, oko kuthetha ukuba ulele ngokupheleleyo. Oogqirha bavula isisu sakho baze basuse zonke iithumba ezibonakalayo zomhlaza kunye nezicubu ezinesifo .
Inyathelo lesiBini: Unyango lwe-HIPEC
Unyango lwe-HIPEC lusetyenziselwa ukutshabalalisa iiseli zomhlaza ezincinci kakhulu ezingabonakaliyo emehlweni emva kokuba iithumba zomhlaza zisusiwe ngotyando.
1. Ukucoca ngeCatheter: Oogqirha bafaka iityhubhu ezininzi (ii-catheter) esiswini sakho. Ezi tyhubhu ziqhagamshelwe kumatshini ofudumeza amayeza e-chemotherapy.
2. Ukunika i-chemo eshushu: Umatshini ufudumeza amayeza e-chemo ukuya kuthi ga kwi-41-42 degrees Celsius (108°F) aze awapompe kwisisu ngetyhubhu.
3. Ukuhanjiswa kwe-Chemo: Iqela lezonyango liza kujikeleza umzimba wakho kancinci ukusuka kwelinye icala ukuya kwelinye, liqinisekisa ukuba isisombululo se-chemo esifudumeleyo sifikelela kuyo yonke ikona yesisu sakho. Oku kuya kuthatha naphi na ukusuka kwimizuzu engama-30 ukuya kwiiyure ezi-2.
4. Ukususwa kwe-chemo: Emva kwexesha elimiselweyo, ulwelo lwe-chemo olufakwe kwisisu luyasuswa ngokupheleleyo. Emva koko indawo iyahlanjwa kwakhona nge-saline ukuze icoceke.
5. Ukuthungwa kwamanxeba: Ekugqibeleni, zonke izithuba ezenziweyo zotyando zithungwa zivaliwe.
Ziziphi iingenelo ezikhethekileyo zonyango lwe-HIPEC?
Xa i-systemic chemotherapy inikwa ngemithambo yegazi, ihamba emzimbeni wonke kunye negazi. Nangona kunjalo, ngenxa yomqobo we-membrane obizwa ngokuba yi-peritoneum ejikeleze umgodi wesisu, kunzima ukuba amayeza e-chemotherapy angene kakuhle kumgodi wesisu.
Kodwa kunyango lwe-HIPEC, kuba sinikezela i-chemo ngqo kwisisu, ingayidlula loo mqobo ize iye apho kukho iiseli zomhlaza ize izitshabalalise.
Ezinye izibonelelo:
- Unyango olunamandla kakhulu lwe-chemotherapy: Ngenxa yokuba la mayeza ashushu, anefuthe elikhulu kwiiseli zomhlaza. Kwakhona, ngenxa yokuba afikelela ngqo kwiiseli zomhlaza, asebenza ngakumbi ekubulaleni iiseli zomhlaza.
- Imijikelo embalwa yonyango: Akukho mfuneko yokunika imijikelo emininzi yechemotherapy njenge-chemotherapy eqhelekileyo. Olu nyango lunokwenziwa ngotyando olunye.
- Iziphumo ebezingalindelekanga ezinciphileyo: Ekubeni amayeza e-chemo ephelela kakhulu esiswini, iziphumo ebezingalindelekanga ezichaphazela umzimba wonke (ukulahleka kweenwele, ukuhlanza kakhulu) ezenzeka ngonyango lwe-chemotherapy oluqhelekileyo zinokuncitshiswa.
Kwenzeka ntoni emva konyango? Kuthatha ixesha elingakanani ukuchacha?
Ngokuxhomekeke kwimeko yakho emva konyango lwe-HIPEC, kunokufuneka uhlale kwigumbi lokhathalelo olunzulu (ICU) kangangeentsuku ezimbalwa. Ungaqhagamshelwa kumatshini "wokuphefumla" ukuze ukuncede uphefumle.
Ngenxa yokuba olu nyango lusebenzisa amayeza anamandla e-chemotherapy, unokunikwa ukutya ngetyhubhu yokondla de umsebenzi wakho wamathumbu ubuyele esiqhelweni.
Ezi ziphumo zilandelayo zinokwenzeka ngexesha lokuchacha:
- Ukuzalisa isisu
- Ukuqhinwa okanye urhudo
- Ukudinwa
- Isicaphucaphu nokuhlanza
- Intlungu kwindawo yotyando
- Ukudumba komzimba (ngenxa yetyuwa esetyenziswa kunyango)
Kungathatha malunga neeveki ezi-4 ukuya kwezili-12 ukuze umntu aphile ngokupheleleyo. Oku kuquka iveki enye ukuya kwezimbini esibhedlele.
Xa kufuneka uthethe nogqirha ngokukhawuleza
Ukuba ufumana naziphi na ezi mpawu emva kokubuyela ekhaya, kufuneka ufowunele ugqirha wakho ngoko nangoko .
- Ukuba umkhuhlane ungaphezulu kwama-38.3°C (101°F)
- Isicaphucaphu nokuhlanza okungapheliyo
- Ukudumba okugqithisileyo, ukubomvu, okanye ubomvu obujikeleze inxeba lotyando
- Ukuba intlungu iya isiba mandundu
Ezi zinokuba ziimpawu zosulelo okanye inxeba elingapholiyo kakuhle, ngoko ke kubalulekile ukufuna unyango ngokukhawuleza.
Umyalezo Wokuya Ekhaya
- I-HIPEC lunyango olukhethekileyo noluphucukileyo lomhlaza osele usasazeke esiswini.
- Apha, iiseli zomhlaza ezibonakalayo ziqala zisuswe ngotyando, emva koko amayeza e-chemotherapy ashushu asetyenziswa ukutshabalalisa iiseli zomhlaza ezingabonakaliyo.
- Nangona olu nyango lungelulo oluphilisa umhlaza ngokupheleleyo, lunceda kakhulu ekwandiseni ubomi bomguli kunye nokunciphisa iimpawu.
- Olu lutyando olunzima kakhulu, kwaye ukuchacha kuthatha iiveki ezininzi.
- Ukuba olu nyango lucetyisiwe kuwe okanye kumntu osondeleyo kuwe, kubaluleke kakhulu ukuba nengxoxo evulekileyo nepheleleyo nogqirha wakho malunga neenzuzo, iingozi kunye neziphumo zalo.
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