Ngaba uziva ubuhlungu? Ngaba amalungu akho omzimba ayaphelelwa ngamandla? Oku kusenokuba yi-Inclusion Body Myositis (IBM)!

Ngaba ngamanye amaxesha uziva ngathi kunzima ukubamba izinto, ukucinezela iqhosha, okanye nokuhamba? Usenokuba ucinga, "Owu, le yinto eyenzekayo xa ukhula." Kodwa ngamanye amaxesha, ezi zinto azilula kangako. Namhlanje, siza kuthetha ngemeko engaqhelekanga kodwa ebaluleke kakhulu ekufuneka uyiqaphele. Oko kubizwa ngokuba yi-'Inclusion Body Myositis', ekwaziwa ngokuba yi-'(IBM)' ngamafutshane.

Yintoni i-'Inclusion Body Myositis (IBM)'? Masiyiqonde ngokulula!

Ngamafutshane, i-'Inclusion Body Myositis' yimeko eyenza izihlunu zakho zibe buthathaka kancinci kancinci, kodwa ayibangeli ntlungu ingako. Idla ngokuqala emva kweminyaka engama-50. Cinga ngayo, usenokuba nobunzima bokucinezela into encinci, ube nobunzima bokubamba into ethile, okanye ukhubeke uze uwe xa uhamba nje. Ezi ziimpawu zokuqala onokuzibona.

Le meko, ebizwa ngokuba yi-'IBM', ikhula kancinci kancinci kwiminyaka emininzi. Ayisiyongxaki esongela ubomi. Oku kuthetha ukuba ayizukukubulala. Nangona kunjalo, ngokuhamba kwexesha, inokwenza kube nzima ukwenza imisebenzi yemihla ngemihla, nto leyo enokukhokelela kwinqanaba elithile lokukhubazeka. Ngamanye amaxesha, licala elinye lomzimba wakho elichaphazeleka ngakumbi. Malunga nesiqingatha sabantu abanale meko banokuba 'nengxaki yokuginya'.

Okubuhlungu kukuba, akukho nyango lwe-IBM okwangoku. Kodwa ungakhathazeki! Unyango lomzimba lunokukunceda ugcine amandla emisipha yakho ixesha elide kangangoko unako.

Ixhaphake kangakanani le meko ye-'IBM'?

I-Inclusion Body Myositis yimeko ekwiqela lezifo ezibuthathaka izihlunu ezibizwa ngokuba yi-myopathies. I-Myopathies zizifo ezihlasela kwaye zenze buthathaka imicu yezihlunu zakho. Uphando lubonisa ukuba i-IBM ichaphazela abantu abadala abaphakathi kwe-5 kunye ne-9 kwisigidi ngasinye. Ikwaqheleke ngokuphindwe kathathu kumadoda kunabasetyhini (3:1).

Zithini iimpawu ze-'Inclusion Body Myositis (IBM)'? Masifumanise ngokuchanekileyo!

Ubuthathaka bemisipha obubangelwa yi-IBM buqala kancinci kakhulu. Budla ngokuqala emalungeni. Usenokubona kuqala ubuthathaka emilenzeni, emathangeni, okanye ezandleni, ezihlahleni, okanye kwiminwe. Cinga ngale ndlela: abanye abantu banengxaki yokuqhobosha ihempe, okanye iipeni zabo azibhali kakuhle. Abanye banengxaki yokunyuka izinyuko, okanye bayakhubeka baze bawe ngelixa behamba nje.

Njengoko iimpawu zisiya zisiba mandundu, unokubona izinto ezifana nezi:

• Izihlunu ezingalweni, emilenzeni, emagxeni, esinqeni, ezintendeni zezandla, nakwiminwe ziya zisiba buthathaka kancinci kancinci. Khawuthelekelele, awukwazi ukuphakamisa izinto obukade ukwazi ukuziphakamisa ngokulula, kwaye unengxaki yokuvuka esitulweni.
• Ukubuthathaka kwemisipha entanyeni okanye emqaleni. Oku kunokwenza kube nzima ukubamba intloko ime nkqo, kwenze kube nzima ukuginya ukutya, kwaye kunokubangela nokuba ukutya kubambeke.
• Ukuwohloka kwemisipha kubonakala ngokucacileyo. Oku kuthetha ukuba imisipha iyancipha kwaye incinci kakhulu.
• Iintlungu zemisipha ezithambileyo nezihlala zisenzeka (`myalgia`). Nangona kunjalo, le ntlungu ayiveli kuye wonke umntu, kwaye nokuba iyenzeka, ayibi buhlungu kakhulu.

Umzekelo, khawucinge ukuba unomhlobo ogama linguSunil. Ebengakwazi ukubamba ikomityi yakhe yeti kakuhle ixesha elithile ngoku, iqhubeka iphuma esandleni sakhe. Xa esiya kufunda iphephandaba, isandla sakhe sivakala ngathi siyangcangcazela. Ekuqaleni, wayecinga ukuba kukudinwa nje. Kodwa kamva, waqonda ukuba oku kungaba luphawu lokuqala lwe-'IBM'.

Kutheni le nto isenzeka le `Inclusion Body Myositis (IBM)`? Yintoni unobangela?

Enyanisweni, le meko ibizwa ngokuba yi-'Inclusion Body Myositis' ayisiyongxaki. Oko kukuthi, kubonakala ngathi yenzeka ngaphandle kwesizathu esithile. Njengezinye iintlobo ze-'myositis', kule meko, ukudumba kwexesha elide kwimisipha ('ukudumba okungapheliyo') yeyona nto ibangela ubuthathaka bemisipha. Nangona kunjalo, abaphandi abasazi ukuba kutheni oku kudumba kwenzeka. Bacinga ukuba kusenokuba kungenxa yengxaki kwinkqubo yomzimba yokuzikhusela ('isifo sokuzikhusela') . Oko kukuthi, iiseli ezikhusela umzimba wethu zihlasela iiseli zethu zemisipha ngempazamo.

`Imizimba yokubandakanywa` ikwanxulumene ne`IBM`. Ezi zii -clumps zeproteni ezingaqhelekanga ezifakwa ngaphakathi kweeseli zemisipha. Zinokubangelwa lusulelo lwentsholongwane, umonakalo weeseli, okanye utshintsho lwemfuza . Ezi `mizimba yokubandakanywa` zikwabonakala kwizifo ze-neurodegenerative ezifana ne`ALS`. Zinokuphazamisana nokusebenza okuqhelekileyo kweeseli.

Umahluko phakathi kwe-'Inclusion Body Myopathy' kunye ne-'Inclusion Body Myositis'

Ngamanye amaxesha i-'Inclusion Body Myositis' ikwabizwa ngokuba yi-'sporadic inclusion body myositis (sIBM)`. I-'Sporadic' ithetha ukuba yenzeka ngokungacwangciswanga, okanye ngaphandle kwesizathu esithile. Oku kukwahlula kwiimeko ezifanayo ezifuywayo. Ezo zifuywayo zibizwa ngokuba yi-'hereditary inclusion body myopathies (hIMB)`. Xa sithi 'inclusion body myopathies', zombini ezi ntlobo zezakho. Ngoku sithetha nge-'sIBM' eyenzeka ngokungacwangciswanga.

Ifunyaniswa njani i-'Inclusion Body Myositis'? Zeziphi iimvavanyo ezenziwayo?

Ukuze afumanise ukuba unayo na i-IBM, ugqirha uza kuqala akubuze ngeempawu zakho aze ahlole izihlunu zakho. Iimpawu ze-inclusion body myositis zinokufana nezezinye iimeko, ezifana ne-polymyositis kunye ne-myasthenia gravis. Ugqirha wakho uza kukhangela izinto ezithile ezifana nezi:

• Zeziphi izihlunu ezichaphazelekayo? (umz., kwiminwe okanye emathangeni?)
• Ingaba licala elinye lomzimba elichaphazeleka ngakumbi?
• Ngaba ukuwohloka kwemisipha kubonakala ngokucacileyo?
• Wawuneminyaka emingaphi xa iimpawu zaqala? (Ngokwesiqhelo emva kweminyaka engama-50)

Emva koko, kunokwenziwa uvavanyo oluninzi ukuze kuthintelwe ezinye iimeko, ezinje:

• Uvavanyo lweCreatine Kinase (CK): Olu vavanyo lulinganisa inqanaba le-enzyme ekhethekileyo egazini. Eli nqanaba le-'CK' linokwanda xa kukho umonakalo kwimisipha.
• Uvavanyo lwegazi lweentsholongwane kunye nezifo ezahlukeneyo zokuzikhusela komzimba.
• I-Electromyogram (EMG): Oku kulinganisa umsebenzi wombane kwimisipha yakho. Kwenziwa ngokufaka iinaliti ezincinci kwimisipha.
• Uphononongo lokuHanjiswa kweMithambo (i-NCS): Olu vavanyo lulinganisa isantya apho umbane uhamba khona ngemithambo-luvo (imithambo-luvo yemoto) elawula izihlunu zakho.

Uvavanyo lwe-biopsy yemisipha

Eyona ndlela ilungileyo yokuqinisekisa ukuba unayo na i-inclusion-body myositis kukuthatha iqhekeza elincinci lesicubu (i-biopsy) kwisihlunu esichaphazelekayo. Ingcali yezifo iza kujonga le sampuli yesicubu phantsi kwe-microscope. Ukuba une-IBM, iya kukwazi ukubona imizimba ye-inclusion (ii-protein clumps ezingaqhelekanga, amaqamza, okanye ii-vacuoles) kwisampuli.

Ngaba kukho naluphi na unyango olusebenzayo lwe-'Inclusion Body Myositis'?

Ngelishwa, akukho nyango lusebenzayo lwe-inclusive body myositis. Ngokungafaniyo nezinye iimeko zokudumba kunye nezifo zokuzikhusela komzimba, ayiphenduli kwi-corticosteroids okanye amayeza okunciphisa umzimba.

Kodwa ungalahli ithemba! Unyango lomzimba kunye nokuzilolonga rhoqo kubalulekile ukuze ugcine amandla emisipha yakho ixesha elide kangangoko unako. Ukuzilolonga kunokunceda ukuthintela ubuthathaka bemisipha obungakumbi.

Njengoko isifo siqhubeka kwaye kuba nzima ukwenza imisebenzi yemihla ngemihla, kunokufuneka ufunde iindlela ezintsha zokwenza izinto. Kulapho unyango lomsebenzi lunokunceda khona. Umzekelo, banokukufundisa indlela yokusebenzisa izixhobo ezahlukeneyo ukukunceda unxibe, utye, kwaye ubhale. Abanye abantu banokufuna ukufunda nendlela yokusebenzisa isitulo esinamavili. Ukuba unengxaki yokuginya, ingcali yezifo zolwimi lwentetho (SLP) inokukunceda. Banokukufundisa indlela yokuginya ngokukhuselekileyo kwaye benze umthambo wokuginya.

Ukuba ndine-`Inclusion Body Myositis`, ndimele ndilindele ntoni?

Ukuba une-'IBM', iya kwanda kancinci kancinci. Njengoko benditshilo ngaphambili,Oku akuyi kuyichaphazela indlela ophila ngayo ubomi bakho. Nangona kunjalo, kunokuba nefuthe kumgangatho wobomi bakho. Kusenokufuneka uthembele kwabanye okanye ufunde iindlela ezintsha zokwenza izinto. Uninzi lwabantu aluphulukani namandla abo okuhamba ngokupheleleyo, kodwa abanye banokufuna isitulo esinamavili emva kweminyaka eli-10-15.

Ndingazinyamekela njani ngelixa ndiphila ne-inclusive-body myositis?

Kuya kufuneka uphile `ne-Inclusion body myositis` ixesha elide, kwaye kunokuba nzima kancinci ngokuhamba kwexesha. Eyona ndlela ilungileyo yokujongana noku kukwenza isicwangciso sexesha elide sokunyamekela impilo yakho yomzimba neyengqondo. Oko kuthetha ukuqhubeka nokuziqhelanisa nemikhwa emincinci ekunceda uhlale uphilile. Umzekelo:

• Qhubeka nenkqubo yakho yokuzilolonga. Usenokuba ukwi-physiotherapy, okanye usenokuba utshintshele kwinkqubo yokuzilolonga yasekhaya. Ukuqhubeka nale nkqubo kuya kunceda ukugcina izihlunu zakho zomelele kangangoko kunokwenzeka.
• Landela "indlela yokuphila impilo entle." Ukuba utya kakuhle, ulala kakuhle, ulawula uxinzelelo, kwaye ugcina ubudlelwane bakho obubalulekileyo, uya kuziva ungcono ngokubanzi.
• Joyina amaqela enkxaso. Ungafumana amandla engqondo amaninzi kunye neengcebiso ezisebenzayo kwabanye abantu abaye badlula okanye abadlula kwinto efanayo nawe. Kukwamnandi ukuziva ngathi "andindim ndedwa odlula kule nto."
• Jonga iindlela zokuziqhelanisa ekhaya nasemsebenzini. Kukho izixhobo ezininzi zokuncedisa ukuhamba kunye nezixhobo zokuncedisa ezinokunceda abantu abakhubazekileyo ukuba benze imisebenzi yemihla ngemihla ibe lula.
• Bona ugqirha wakho rhoqo. Hlala unxibelelana nogqirha wakho. Xelela ugqirha wakho ngoko nangoko ukuba ubona naziphi na iimpawu ezintsha, ezinje ngobunzima bokuginya, okanye ukuba uphawu olukhoyo luya lusiba mandundu.
• Jonga uvavanyo lweklinikhi. Abaphandi bahlala bekhangela unyango olutsha olunokunceda kwi-inclusive body myositis. Ungathabatha inxaxheba kwezi zilingo.

Le meko, ebizwa ngokuba yi-'Inclusion body myositis', idla ngokuvela kwiminyaka yoo-20 ubudala, xa kungekho themba. Akukho mntu ulindele ukuba ngequbuliso afumane isifo esinganyangekiyo nesiqhubekekayo. Kunokuba nzima ukujamelana naso nokuchazela abo bakukhathaleleyo, ingakumbi ukuba abakaze beve ngesi sifo ngaphambili.

Kodwa khumbula, esi sisifo esikhula kancinci. Ngoko ke, kukho ixesha elaneleyo lokucinga ngotshintsho oluzayo nokwenza uhlengahlengiso ngokufanelekileyo. Akukho mntu unokutsho ngokuqinisekileyo ukuba oku kuya kukuchaphazela njani. Kodwa,Ngokusebenzisa indlela enethemba, zininzi izinto onokuzenza ukuze ugcine impilo yakho yonke kunye nokuphila kakuhle kwiminyaka ezayo.

Izinto ezibalulekileyo ekufuneka sizikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ngoko ke sithethe kakhulu nge-'Inclusion Body Myositis (IBM)'. Okokugqibela, nazi izinto ezibalulekileyo ekufuneka uzikhumbule:

• I-IBM sisifo sobuthathaka bemisipha esiqhubekayo esixhaphakileyo emva kweminyaka engama-50. Intlungu ayinzima, kodwa ekuhambeni kwexesha inokuchaphazela imisebenzi yemihla ngemihla.
• Akukho nyango loku , kodwa unyango lomzimba kunye nokuzilolonga kunokunceda ukugcina amandla emisipha ixesha elide kangangoko kunokwenzeka.
• Iimpawu zingabandakanya ubunzima bokubamba izinto, ukukhubeka xa uhamba, kunye nobunzima bokuginya ukutya .
• Isizathu esichanekileyo asikaziwa (`idiopathic`), kodwa isenokuba yingxaki kwinkqubo yomzimba yokuzikhusela.
• Esi sifo siqinisekiswa ngokuqinisekileyo kuphela nge-biopsy yemisipha.
• Oku akusongeli ubomi , kodwa kunokuchaphazela umgangatho wobomi.
• Kubaluleke kakhulu ukuhlala unethemba, ulandele iingcebiso zonyango, kwaye ufumane inkxaso efunekayo.

Ukuba wena okanye umntu omaziyo uhlangabezana nezi mpawu, kungcono ukufuna ingcebiso kagqirha. Khumbula, awuwedwa, baninzi abantu abanokukunceda!

Ubuthathaka bemisipha , isifo se-IBM, unyango lomzimba, izifo zemisipha, impilo yabantu abadala, ubunzima bokuginya, izifo zemithambo-luvo