Nokuba sisiva igama elithi "umhlaza," sihlala sisoyika kwaye sixhalabile. Kodwa ngenxa yenkqubela phambili kwezonyango namhlanje, kukho amayeza akhethekileyo anokujolisa kwaye anyange iiseli zomhlaza kuphela. Ngoko ke namhlanje, siza kuthetha ngeyeza elibizwa ngokuba yi-"Lenvatinib," elithintela ukukhula kweeseli zomhlaza kwaye lizise ithemba kubantu abaninzi.
Yintoni iLenvatinib?
Ngamafutshane, i-lenvatinib liyeza elijolise kwiiproteni ezithile kwiiseli zomhlaza, lilawula ukukhula kwazo kunye nokusasazeka kwazo. Oku kubizwa ngokuba "lunyango olujoliswe kulo." Oogqirha badla ngokunika eli yeza ukunyanga iintlobo ezahlukeneyo zomhlaza.
- Umhlaza we-endometrial
- Umhlaza wezintso
- Umhlaza wesibindi
- Umhlaza we-thyroid
Ngaphandle koku, ugqirha wakho angacebisa eli yeza nakwezinye iimeko zonyango.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba uqale unyango nge-lenvatinib, kubaluleke kakhulu ukuxelela ugqirha wakho ngembali yakho epheleleyo yempilo. Ingakumbi ukuba unayo nayiphi na kwezi meko zilandelayo:
- Izifo zamazinyo okanye iintsini.
- Isifo seswekile (amanqanaba aphezulu eswekile egazini).
- Igazi elonyukayo.
- Isifo sentliziyo okanye iingxaki zokujiya kwegazi.
- Ukubetha kwentliziyo okungaqhelekanga.
- Amanqanaba aphantsi e-calcium, i-magnesium, okanye i-potassium egazini.
- Isifo samathumbu esidumbileyo.
- Isifo sezintso okanye sesibindi.
- Ukubakho kweproteni kumchamo.
- Ukuba usandul’ utyando okanye uceba ukulutyanda kwixesha elizayo.
- Ezinye izifo ze-thyroid gland.
- Ukuba une-allergy kule yeza (iLenvatinib) okanye naliphi na elinye iyeza, ukutya, idayi, okanye isithinteli.
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa.
Ndingayisebenzisa njani le yeza kanye kanye?
Kubaluleke kakhulu ukusela eli yeza kanye njengoko ugqirha wakho ekuyalele, ngedosi echanekileyo, nangexesha elifanelekileyo.
- Ginya ezi kapsuli ziphelele ngeglasi yamanzi.
- Musa ukuphula, ukutyumza, okanye ukuhlafuna iikhaphu. Ziginye ziphelele.
- Zama ukusela amayeza ngexesha elifanayo yonke imihla.
- Musa ukuyeka ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha wakho.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi kokuba uthathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi oyiphosileyo.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe eli yeza ngaphezu kokuba kufanele, nxibelelana neZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane. Eli yeza limiselwe wena kuphela. Ungaze wabelane ngalo nabanye.
Amanye amayeza anokusebenzisana nale mayeza
I-Lenvatinib liyeza elinokusebenzisana namanye amayeza. Ngoko ke xelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka iivithamini, iimveliso zezityalo, kunye nezongezo. Lumka ngakumbi ngamayeza akwitheyibhile engasezantsi.
| Amachiza anokusebenzisana neLenvatinib | |
|---|---|
| Ungaze uthathe la mayeza ane-lenvatinib: | |
| I-Cisapride | I-Dronedarone |
| I-Pimozide | I-Thioridazine |
| Qiniseka ukuba uxelela ugqirha wakho ukuba usebenzisa la mayeza: | |
| Amanye amayeza asetyenziswa ukunyanga ukubetha kwentliziyo okungaqhelekanga (umz. i-Amiodarone, i-Quinidine) | Amanye amayeza okubulala iintsholongwane (umz. i-Azithromycin, iClarithromycin) |
| Amanye amayeza okugula ngengqondo kunye nokudakumba | Amayeza okulwa nefungus (umz. iKetoconazole, iFluconazole) |
| Amanye amayeza andisa ixesha le-QT | Amanye amayeza amaninzi (olu luhlu aluphelelanga) |
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa iyeza
Ufanele unikele ingqalelo ekhethekileyo kwimpilo yakho ngalo lonke ixesha lonyango.
Uvavanyo lwezonyango
Bona ugqirha wakho ngemihla emiselweyo uze wenze uvavanyo lwegazi olufunekayo kunye nolunye uvavanyo, njengoko oku kubalulekile ukujonga imiphumo yale mayeza emzimbeni.
Ukukhulelwa kunye nokuncancisa
Oku kubaluleke kakhulu: Musa ukukhulelwa ngelixa usela eli yeza kwaye emva kweentsuku ezingama-30 uyeke ukulisebenzisa. Linokubangela ingozi enkulu kumntwana wakho. Kwakhona, musa ukuncancisa ngelixa usela eli yeza kwaye emva kweveki enye uyeke ukulisebenzisa. Ukuba uceba ukuba nabantwana, thetha nogqirha wakho ngalo mba.
Utyando kunye nokwenzakala
Ukuba uza kwenziwa utyando, xelela ugqirha wakho. Eli yeza linokulibazisa ukuphola kwenxeba. Ke ngoko, kucetyiswa ukuba uyeke ukulisebenzisa iyeza iveki ngaphambi kotyando kwaye ungaliqalisi kwakhona de kube ziiveki ezimbini emva kotyando. Eli yeza kufuneka liqalwe kwakhona kuphela emva kokuba inxeba lipholile ngokupheleleyo.
Impilo yamazinyo neentsini
Eli yeza linokubangela ukopha. Ngoko ke lumka kakhulu xa uhlamba amazinyo akho kwaye ufaka i-floss. Ukuba uza kufumana naluphi na unyango lwamazinyo, qiniseka ukuba uxelele ugqirha wakho wamazinyo ukuba usela eli yeza.
Zeziphi iziphumo ebezingalindelekanga endinokuzifumana?
Njengalo naliphi na iyeza, i-lenvatinib inokubangela iziphumo ebezingalindelekanga. Ezinye zimbi kakhulu, ngelixa ezinye zincinci. Kubalulekile ukuxela ugqirha wakho naziphi na iimpawu ezingaqhelekanga.
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha ngoko nangoko | |
|---|---|
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ukopha okungaqhelekanga | Indle emnyama okanye engapheliyo; ukuhlanza okufana nekofu; ukuphuma kwegazi empumlweni okanye kwiintsini; amabala abomvu eluswini. |
| Utshintsho kwisantya sentliziyo | Ubunzima bokuphefumla, iintlungu zesifuba, isiyezi, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga. |
| Umonakalo wesibindi okanye wezintso | Ukutyheli kwamehlo okanye ulusu, umchamo otyheli/omdaka omnyama, iintlungu kwicala eliphezulu lasekunene lesisu, ukuncipha kokuphuma komchamo. |
| Iimpawu zeStroke | Ubuthathaka bobuso, ingalo, okanye umlenze ngequbuliso; ubunzima bokuthetha; intloko ebuhlungu; ubunzima bokuhamba. |
| Ezinye iimpawu ezinzulu | Intloko ebuhlungu kakhulu, uxinzelelo lwegazi oluphezulu, ukuxhuzula, iintlungu zamazinyo, ukudumba kweqatha. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Urhudo | Umnqweno wokutya |
| Intlungu yamalungu kunye nemisipha | Izilonda zomlomo |
| Isicaphucaphu nokuhlanza | Ukuhla ukusinda |
Kuqhelekile ukuba uzive ungakhululekanga kwaye udiniwe ngexesha lonyango lomhlaza. Oku kungenxa yokuba la mayeza achaphazela zombini iiseli zomhlaza kunye neeseli eziphilileyo ngandlela thile. Nangona kunjalo, nangona ezi ntlungu zinjalo, iziphumo ezilungileyo zinokufumaneka ngokuqhubeka nonyango njengoko kuyalelwe ngugqirha wakho.
Umyalezo Wokuya Ekhaya
- I-Lenvatinib liyeza elijolise kwiiseli zomhlaza. Lithathe kanye njengoko ugqirha wakho ekuyalele, kwaye ngexesha elifanelekileyo.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo kunye nazo zonke iimeko zempilo onazo.
- Ukuba ubona iziphumo ebezingalindelekanga ezinzulu (ukopha okungaqhelekanga, utshintsho kwisantya sentliziyo, iimpawu zestroke), yazisa ugqirha wakho okanye isibhedlele ngoko nangoko.
- Kuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweentsuku ezingama-30 uyeke ukuncancisa.
- Eli liyeza elimiselwe wena kuphela. Ungaze wabelane ngalo nabanye.
- Thetha ngokukhululekileyo nogqirha wakho ngayo nayiphi na imibuzo okanye izinto ezikuxhalabisayo. Khumbula ukuba awuwedwa.
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