Ingaba unethumba elingaqhelekanga kwinkqubo yakho yemithambo-luvo? (Ithumba elibi leNerve Peripheral Nerve Sheath Tumor - MPNST) Masifunde ngalo.

Ngaba wakha waziva iqhuma ndaweni ithile emzimbeni wakho, mhlawumbi engalweni okanye emlenzeni, elikhula kancinci kancinci? La maqhuma, ngamanye amaxesha anokuqala amancinci njenge-pea aze akhule abe makhulu njenge-orenji, yiloo nto siza kuthetha ngayo namhlanje. Le yimeko embi kakhulu, kodwa engaqhelekanga. Ibizwa ngokuba yi-malignant peripheral nerve sheath tumor, okanye i-MPNST ngamafutshane.

Yintoni i-malignant peripheral nerve sheath tumor (MPNST)?

Ngamafutshane, i-MPNST (i-Malignant Peripheral Nerve Sheath Tumor) sisifo somhlaza esingaqhelekanga esikhula kwiindawo ezikhuselayo (ii-nerve sheaths) ezijikeleze imithambo-luvo emzimbeni wakho. Ezi zezohlobo lwe- sarcoma yezicubu ezithambileyo . Zivela kwinkqubo yakho yemithambo-luvo engaphandle . Cinga ngayo, unokufumana ezi thumba ezingalweni nasemilenzeni yakho. Ayisiyiyo loo nto kuphela, ngamanye amaxesha zinokukhula nakwi-pelvis, esiswini, entloko, nasentanyeni. Ezi thumba zinokunyangwa ngokuzisusa ngotyando. Nangona kunjalo, kufuneka sikhumbule ukuba ngamanye amaxesha ezi thumba zinokuphinda zibuye .

Inqabile kangakanani i-MPNST?

Le yimeko engaqhelekanga kakhulu. Kuphela ngumntu omnye kwabayi-100,000 ofunyaniswa enale ngxaki ye-malignant peripheral nerve sheath tumor (MPNST) minyaka le. Idla ngokuchaphazela abantu abaphakathi kweminyaka engama-30 ukuya kwengama-50 ubudala .

Ukongeza, abantu abane-genetic disorder ebizwa ngokuba yi -Neurofibromatosis type 1 (NF1) banamathuba amaninzi okufumana i-MPNST. Kufunyenwe ukuba phakathi kwama-25% nama-50% abantu abane-MPNST nabo bane-NF1 .

Ngokubanzi, i-MPNST inokukhula kwangethuba kubantu abane-NF1 kunakubantu abangenayo i-NF1. Kwakhona, amadoda ane-NF1 anamathuba amancinci okukhula kwi-MPNST kunalawo angenayo i-NF1.

Zithini iimpawu ze-MPNST?

Ii-MPNST zinokukhula naphi na kwimithambo-luvo yakho engaphandle, kodwa zihlala zichaphazela iindawo ezifana neengalo nemilenze yakho. Ngamanye amaxesha zinokukhula nakwiindawo ezifana ne-pelvis yakho, isifuba, isisu, okanye intloko nentamo. Iimpawu ze-MPNST ziquka:

• Iqhuma elikhula kancinci phantsi kwesikhumba. La maqhuma anokuba mancinci njenge-pea (malunga neesentimitha ezi-2) okanye abe makhulu njenge-orenji (malunga neesentimitha ezili-10).
• Ukuziva intlungu (ingakumbi ukuba une-NF1).
• Ukungabi nangqondo (iParesthesia).
• Ukuziva ubuthathaka kwiingalo nasemilenzeni.

Zithini izizathu ze-MPNST?

Izifundo zibonise ukuba ama-50% eethumba zemithambo-luvo ezinobungozi ezibangelwa yi -neurofibromatosis type 1 (NF1).Le meko ibizwa ngokuba yi. Ezinye izizathu zinokuba:

• Unyango ngemitha: Malunga ne-10% yabantu abane-MPNST bafumene unyango ngemitha kwezinye izifo.
• Utshintsho lwemfuza: Abaphandi bafumanise ukuba kukho utshintsho olwahlukeneyo lwemfuza olubangela ukuba iiseli zemithambo-luvo eziqhelekileyo zibe ziiseli ezingaqhelekanga, zande, kwaye zenze amathumba.
• Ezinye iintlobo ze-neurofibromas: Abantu abane -plexiform neurofibroma basengozini enkulu yokuhlaselwa yi-MPNST.

Ifunyaniswa njani i-MPNST?

Xa ubona ugqirha, uya kuqala enze uvavanyo lomzimba aze akubuze ngempilo yakho ngokubanzi. Oku kuya kuquka ukubuza ngembali yakho yezonyango, imbali yezonyango yosapho, kunye nazo naziphi na iimpawu onokuba unazo. Ukongeza, banokwenza oku kulandelayo:

• Uvavanyo lwemifanekiso: Oogqirha banokwenza uvavanyo olufana ne -MRI (Magnetic Resonance Imaging) kunye ne -PET (Positron Emission Tomography) scans .
• I-Biopsy: Ugqirha angenza i-biopsy, athathe isampuli yezicubu aze azihlolisise phantsi kwe-microscope yingcali yezifo .
• Uvavanyo lwemfuza: Ukuba unethumba elibi elikwi-peripheral nerve sheath tumor, ugqirha wakho unokucebisa uvavanyo lwemfuza ukuze kubonwe ukuba wena okanye ilungu losapho olusondeleyo lune -neurofibromatosis type 1 (NF1) okanye olunye uhlobo lwethumba elikwi-nerve sheath tumor , i-neurofibromatosis type 2 (Schwannomatosis) .

Ziziphi iindlela zonyango ze-MPNST?

Oogqirha badla ngokwenza utyando lokususa ithumba elinobungozi elikwi-peripheral nerve sheath. Nangona kunjalo, kukho iimeko apho utyando lungenakwenzeka. Umzekelo:

• Amantongomane amakhulu (amantongomane angama-5 cm nangaphezulu).
• Iithumba ezikhula ngokukhawuleza emzimbeni.
• Iithumba ezikufutshane kakhulu neenethiwekhi zemithambo-luvo ezintsonkothileyo zinokonakala ngexesha lotyando.

Kwezi meko, oogqirha banokunyanga i-MPNST ngokudibanisa utyando, i-chemotherapy , okanye unyango lwe-radiation . Unyango lwe-radiation lunokunikwa ngaphambi okanye emva kotyando.

Abaphandi ngoku bajonga ukuba ingaba unyango olujoliswe kwi-immunotherapy okanye unyango olujoliswe kulo lungasetyenziswa njengonyango olutsha. Ukuba une-malignant peripheral nerve sheath tumor, ungafaneleka kwisilingo seklinikhi esivavanya unyango olutsha.Kungaba ngumbono olungileyo ukuthetha nogqirha wakho malunga nokuthatha inxaxheba.

Ziziphi iingxaki okanye iziphumo ebezingalindelekanga zonyango?

Iingxaki ezinokwenzeka ngexesha lotyando ziquka:

• Iimpendulo kwi-anesthesia jikelele.
• Ukopha kakhulu (ukopha igazi).
• Intlungu.
• Amanxeba otyando.
• Usulelo lwenxeba ngotyando.

Unyango olufana ne-chemotherapy okanye unyango lwe-radiation lunokubangela iziphumo ebezingalindelekanga ezifana nezi:

• Urhudo.
• Ukudinwa.
• Isicaphucaphu nokuhlanza.

Ithini ingqikelelo yomntu one-MPNST?

Ukuxela kwangaphambili yinto iqela lakho lezonyango elicinga ukuba uza kuba yiyo emva kokuba ugqibile unyango. Kwimeko ye-MPNST, olu qikelelo lumiselwa zizinto ezininzi:

• Imeko ye-NF1: Xa la mathumba ekhula kubantu abane-NF1, ingqikelelo yokuchacha isenokuba phantsi kancinci kunakubantu abangenayo i-NF1.
• Uhlobo lwesifo: Iingcali zezifo zijonga iiseli phantsi kwe-microscope kwaye zihlela ii-tumor njengeziphezulu okanye ezisezantsi . Ii-tumor ezikumgangatho ophezulu zinethuba eliphezulu lokuba neeseli zomhlaza ezahlukana ngokukhawuleza kwaye zisasazeke.
• Ubungakanani bethumba: Iithumba ze-MPNST zingafikelela kwiisentimitha ezili-10. Iithumba ezinkulu zihlala kunzima ukuzisusa ngotyando.
• I-Metastasis: Ukuba ithumba lisasazeke kwezinye iindawo ukusuka apho laqala khona, kunokuba nzima ukulinyanga.

Njengoko ubona, zininzi izinto ezinokuchaphazela amathuba akho okuchacha, kwaye azizizo zonke ezi zinto ezinokusebenza kuwe. Ke ngoko, kungcono ubuze ugqirha wakho iinkcukacha ezichanekileyo zemeko yakho. Ekubeni eyazi imeko yakho, angakunika ulwazi oludingayo.

Zithini izinga lokusinda kwi-MPNST?

Amanani okusinda asekelwe kumava abanye abaye baba neethumba ze-nerve sheath ezinobungozi. Ngenxa yokuba ezi thumba zinqabile, kunzima kwiingcali ukunika amanani achanekileyo. Ngokutsho kweNational Cancer Institute (US), phakathi kwama-23% nama-69% abantu abane-MPNST baphila iminyaka emihlanu emva kokufunyaniswa ukuba banayo. Olu luhlu lukhulu, akunjalo? Ngoko ke kungcono ukubuza ugqirha wakho ngemeko yakho.

Ndingazinyamekela njani?

Ukuba une-malignant peripheral nerve sheath tumor, ujongene nomhlaza ongaqhelekanga onokubuya emva konyango. Kukho iinkqubo ezininzi ezinokukunceda kule meko:

• Ukhathalelo lokudambisa intlungu:Kwinkonzo yokhathalelo lwentlungu, uza kusebenza neqela loogqirha abaqeqeshwe ngokukodwa abanokukunceda ulawule iimpawu ze-MPNST kunye nemiphumo emibi yonyango. Ngaphezu koko, baya kukunika nenkxaso yengqondo.
• Iinkqubo zokusinda kumhlaza: Umhlaza ufana nohambo. Iinkqubo zokusinda kumhlaza ziyakukhokela ukususela kumhla oxilongwa ngawo, ngonyango lwakho, kunye nento omawuyenze ukuba umhlaza ubuya.

Xa ujonga okokuqala, ithumba elibi elisecaleni kwemithambo-luvo (MPNST) engalweni okanye emlenzeni wakho lisenokubonakala ngathi liqhuma onokuthi ulimele okanye ulimele ngokulula. Ukufumanisa ukuba eli qhuma luhlobo olungaqhelekanga lomhlaza kwaye lifuna utyando kunokuba yinto eyoyikisayo. Kunokuba nzima ukuliqonda. Ukuba unemibuzo malunga nemeko yakho okanye into onokuyilindela, iqela lakho lezonyango liyaqonda. Baya kukuvuyela ukuthatha ixesha lokuphendula imibuzo yakho baze bajongane nayo nayiphi na inkxalabo onokuba nayo.

Umyalezo oza kugoduka nawo kweli nqaku

Kulungile, ngoko ke ndiyathemba ukuba uyaqonda esi sifo somhlaza esingaqhelekanga esibizwa ngokuba yi-MPNST esisithethe ngaso namhlanje. Khumbula, esi sisifo esingaqhelekanga kakhulu. Ukuba unamaqhuqhuva angaqhelekanga, iintlungu, ukungaziva, njl.njl. emzimbeni wakho ahlala ekhona, ngokuqinisekileyo bona ugqirha kwaye ufumane ingcebiso. Okukhona sifunyanwa kwangethuba, kokukhona kulula ukunyanga.

Eyona nto ibalulekileyo kukuba awuwedwa. Iqela lakho lezonyango, usapho, kunye nabahlobo bakho bonke bakhona ukukunceda. Eyona nto ibalulekileyo kukuhlala uqinile kwaye ulandele iingcebiso zikagqirha wakho.

Ithumba elibi le-peripheral nerve sheath, i-MPNST, umhlaza wemithambo-luvo, ithumba, umhlaza, i-neurofibromatosis, i-NF1, utyando, unyango lwemitha, i-chemotherapy