Ngaba une-cholesterol ephezulu efunyenwe njengelifa? Ngamanye amaxesha kunzima kakhulu ukulawula le meko ngeepilisi ze-cholesterol eziqhelekileyo, ulawulo lokutya, kunye nokuzilolonga kuphela. Ukulawula amanqanaba aphezulu e-cholesterol abangelwa zizizathu zemfuza, oogqirha ngamanye amaxesha bacebisa uhlobo oluthile lwenaliti. Namhlanje sithetha ngenaliti ekhethekileyo enjalo, iMipomersen.
Yintoni iMipomersen?
Ngamafutshane, iMipomersen liyeza elinikwa ukunciphisa amanqanaba e-cholesterol embi egazini lakho. Eli asilo pilisi yakho ye-cholesterol eqhelekileyo. Isetyenziselwa ngokukodwa abantu abaneengxaki zemfuza ezibizwa ngokuba yi-familial hypercholesterolemia.
Eli yeza alisetyenziswa lodwa. Lisetyenziswa kunye nokutya okufanelekileyo kunye namanye amayeza e-cholesterol amiselwe ngugqirha wakho . Igama lophawu lwale yeza yiKynamro. Eli yeza lingasetyenziselwa nezinye iimeko. Ngoko ke, ukuba unemibuzo, buza ugqirha wakho.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba akunike isitofu sokugonya seMipomersen, ugqirha wakho kuya kufuneka azi imbali yakho epheleleyo yempilo. Qiniseka ukuba ubaxelela ngezi zinto ngokukodwa.
- Ukuba usela kakhulu: Oku kubaluleke kakhulu kuba ukudibana kwale mithi kunye notywala kwandisa umngcipheko wokonakala kwesibindi.
- Ukuba unesifo sezintso.
- Ukuba unesifo sesibindi.
- Ukuba une-allergies kwiMipomersen okanye nakweyiphi na enye imithi, ukutya, okanye idayi.
- Ukuba ukhulelwe okanye unethemba lokukhulelwa.
- Ukuba ungumama oncancisayo.
Ngokusekelwe kolu lwazi, ugqirha uya kugqiba ukuba eli yeza lifanelekile kuwe okanye akunjalo.
Isetyenziswa njani kanye kanye le gonyo?
Le yinaliti phantsi kwesikhumba. Ungakhathazeki, ugqirha okanye umongikazi oqeqeshiweyo uza kukubonisa indlela yokuzijova ekhaya. Kufuneka ulandele imiyalelo ngqo . Uya kuyifumana ngexesha elimiselweyo, malunga kanye ngeveki. Musa ukuyisebenzisa rhoqo kunokuba ugqirha wakho ekuxelele.
Wenza ntoni ngeenaliti ezisetyenzisiweyo?
Ungaze ulahle iinaliti neesirinji ezisetyenzisiweyo enkunkuma. Kuyingozi kakhulu. Zifanele zifakwe kwisikhongozeli esikhethekileyo se-sharps onokusikhupha. Ukuba awunayo, cela ugqirha wakho akunike enye.
Imiyalelo ekhethekileyo malunga namayeza
Xa unikwa eli yeza, uza kufumana incwadana yemiyalelo ekhethekileyo (iMedGuide) kunye nalo. Funda loo ncwadana ngononophelo ngalo lonke ixesha usela eli yeza. Iqulethe ulwazi oluninzi olubalulekileyo.
Kuthekani ukuba ndisebenzisa i-overdose?
Ukuba ngempazamo uzifake inaliti engaphezulu kwedosi emiselweyo, musa ukulibazisa. Tsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ekubeni le yidosi kanye ngeveki, kunokwenzeka ukuba uyilibale. Masithi uthatha inaliti yakho rhoqo ngoMvulo. Ukuba uyalibala kwaye ukhumbule ngoLwesithathu, thatha idosi ngokukhawuleza nje ukuba ukhumbule.
Nangona kunjalo, ukuba uyakhumbula ngoLwesihlanu, oko kuthetha ukuba kusele iintsuku ezingaphantsi kwe-3 ngaphambi kokuba uthathe idosi yakho elandelayo ngoMvulo, yitsibe loo mini uze uthathe igonyo njengesiqhelo ngoMvulo olandelayo. Ungaze uthathe idosi ephindwe kabini okanye uthathe iidosi ezongezelelweyo.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa eli yeza:
Ingozi yokonakala kwesibindi
Umngcipheko ophambili wale chiza kukwenzakala kwesibindi .
Ukusela utywala ngelixa usebenzisa eli yeza kwandisa umngcipheko wokonakala kwesibindi. Ngoko ke, kuphephe ukusela isiselo esinotywala esingaphezu kwesinye ngosuku. Thetha nogqirha wakho ngale nto.
Umngcipheko womhlaza
Eli yeza linokunyusa umngcipheko weentlobo ezithile zomhlaza. Musa ukoyika oku, thetha ngokukhululekileyo nogqirha wakho kwaye uqonde iingozi.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengayo nayiphi na iyeza, eli linokuba nemiphumo emibi. Eminye iyingozi, eminye ixhaphakile. Masiziqonde ngokucacileyo kwitheyibhile engasezantsi.
| Iziphumo ebezingalindelekanga zeMipomersen | |
|---|---|
| Izinto onokuzixelela ugqirha wakho ngoko nangoko: | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Iingxaki zesibindi | Umchamo omnyama, indle ekhanyayo, ukutyheli kwamehlo okanye ulusu, iintlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya, isicaphucaphu. |
| Ezinye iimpawu ezinzulu | Ukuziva ungaphilanga okanye umkhuhlane, udiniwe okanye ubuthathaka ngendlela engaqhelekanga. |
| Izinto ezingaqhelekanga ukuba zimbi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka: | |
| Intloko ebuhlungu | Intloko ebuhlungu ngokubanzi. |
| Isicaphucaphu | Ukuziva ngathi uhlanza. |
| Ukungonwabi kwindawo yokutofa | Intlungu, ukubomvu, okanye ukudumba apho kufakwe khona inaliti. |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, xelela ugqirha wakho ngazo.
Ngaba kukho iingxaki ngamanye amayeza? (Ukusebenzisana kwamayeza)
Ewe, iMipomersen inokusebenzisana namanye amayeza owasebenzisayo. Oku kunokunyusa umngcipheko wokonakala kwesibindi. Kufuneka ulumke ngakumbi ukuba usebenzisa la mayeza alandelayo:
- I-Acetaminophen
- i-amiodarone
- i-isotretinoin
- i-lomitapide
- i-methotrexate
- tamoxifen
- i-tetracycline
Olu luhlu aluphelelanga. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza, iivithamini, amayeza emifuno, kunye nezongezo ozithathayo. Kwakhona xelela ugqirha wakho ukuba uyatshaya okanye usela utywala.
Ungayigcina njani iyeza?
- Musa ukugcina eli yeza likufutshane nabantwana.
- Gcina efrijini kubushushu obuphakathi kwe-2 kunye ne-8 degrees Celsius (2-8 °C).
- Ukuba awunayo ifriji, ungayigcina kubushushu begumbi (20-25 °C) ukuya kuthi ga kwiintsuku ezili-14. Kodwa yigcine kwibhokisi yayo yokuqala, kude nobushushu nokukhanya .
Umyalezo Wokuya Ekhaya
- I-Mipomersen yinaliti ekhethekileyo yezifo ze-cholesterol ephezulu ngokwemfuza. Isetyenziswa kunye nokutya kunye namanye amayeza.
- Ngaphambi kokuba uqalise amayeza, xelela ugqirha wakho ngembali yakho epheleleyo yempilo, ingakumbi isifo sesibindi kunye nezintso, kunye nobungakanani botywala obuselayo.
- Umngcipheko wokulimala kwesibindi ngenxa yokusela utywala ngelixa usebenzisa eli yeza uphezulu kakhulu, ngoko ke kuphephe.
- Lumka ngeempawu zokonakala kwesibindi (ukutyheli kwamehlo, umchamo omnyama, iintlungu kwicala lasekunene lesisu). Ukuba oku kuyenzeka, bonana nogqirha ngokukhawuleza.
- Lahla iinaliti ezisetyenzisiweyo ngokukhuselekileyo, kuphela kwisitya esibukhali.
- Eli yeza lelakho kuphela. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
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