Ukuba kukho umntu kusapho lwakho, mhlawumbi umama wakho, utata wakho, okanye umntu omthandayo, onesifo se-Alzheimer's, siyazi ukuba kunzima kangakanani. Amazwi awanakuchaza usizi kunye nokungabi namandla okuzivayo njengoko inkumbulo yakho iphela kancinci kancinci kwaye ungasabazi abantu obathandayo. Nangona kunjalo, ngoku kukho ithemba elincinci kweli thunzi. Kutshanje, i-US Food and Drug Administration (FDA) ivumile iyeza elitsha lesifo se-Alzheimer's.
Yintoni le yeza litsha?
Igama lale yeza lisandul’ ukwamkelwa yi- donanemab . Lithengiswa phantsi kwegama elithi Kisunla. Eli asilo yeza elinikwa bonke abaguli abane-Alzheimer's. Lijoliswe ngokukodwa kubantu abakwinqanaba lokuqala lesi sifo. Oko kukuthi, abo basandul’ ukuqala ukubonisa ukukhubazeka kwinkumbulo nakwizakhono zokucinga. Ngokwezonyango, lifanelekile kwizigulana ezine- mild cognitive impairment okanye i-mild dementia .
Ngamafutshane, isifo sika-Alzheimer sibangelwa kukwanda kohlobo lweproteni engafunekiyo ebizwa ngokuba yi-amyloid engqondweni. Kufana nokuvaleka kombhobho wamanzi okubangelwa luthuli. Ngaphambi kokuba eli yeza litsha linikwe, kufuneka kwenziwe iskeni ukuqinisekisa ukuba isigulane sinazo na ezi amyloid engqondweni yaso.
Yintoni eyona nto ikhethekileyo ngale yeza?
Eyona nto inkulu neyona ibalulekileyo ngale chiza kukuba ayisiyonto idla ubomi bonke. Khawucinge nje, uninzi lwamayeza anje ngala kufuneka athathwe rhoqo. Kodwa umahluko omkhulu nge-donanemab kukuba unyango lunokumiswa emva kokuba ezo ntsalela ze-amyloid ezingafunekiyo engqondweni zisusiwe.
Eli linyathelo elikhulu phambili. Olu vunywa lunika izigulane ukhetho olungakumbi, kunye nethuba lokuchitha ixesha elingakumbi nabantu ababathandayo, kunye neenkumbulo ezingaphezulu.
Iingcali zikholelwa ukuba ngokuyeka unyango ngale ndlela, inani lamaxesha ekufuneka isigulane siye esibhedlele ngawo, ukungonwabi esikufumanayo, kunye neendleko zonyango zinokuncitshiswa kakhulu.
Ngaba akukho zingozi okanye iziphumo ebezingalindelekanga?
Kakade ke, njengayo yonke imithi, kukho iingozi ezithile. Asinakuzityeshela. Umngcipheko ophambili onxulumene nale mithi yimeko ebizwa ngokuba yi -ARIA (Amyloid-Related Imaging Abnormalities) .
Ngamafutshane, oku kunokubangela ukudumba okuncinci ngaphakathi kwengqondo (i-brain edema) okanye ukopha okuncinci kakhulu (i-brain bleeding) . La magama asenokuvakala esoyikisa, kodwa iingcali zithi le ngozi inokulawulwa . Yiyo loo nto kubalulekile ukuba uyiqaphele ngexesha lonyango.Ingqondo ijongwa ngokusondeleyo ngokwenza ii-MRI scans rhoqo. Ukuba kukho utshintsho olubonakalayo, ugqirha uza kuthatha amanyathelo afunekayo.
Ngoko ke, ukuba ucinga ngolu nyango, kubaluleke kakhulu ukuthetha ngokukhululekileyo nogqirha wakho malunga neenzuzo kunye neengozi zalo nyango, oko kukuthi, iingenelo kunye neengozi, ngaphandle kokufihla nantoni na.
| Iingenelo zeDonanemab | Iingxaki kunye neengozi zeDonanemab |
|---|---|
| Isusa ii-amyloid deposits engqondweni ezibangela isifo se-Alzheimer. | Ingozi ye-ARIA (ukudumba okanye ukopha kwengqondo). |
| Inciphisa izinga lokuwohloka kwenkumbulo kunye nobuchule bokucinga. | Kubalulekile ukujonga ubuchopho rhoqo nge-MRI scans. |
| Amathuba okuyeka unyango xa i-amyloid iphelile. | Iziphumo ebezingalindelekanga eziqhelekileyo ezifana nentloko ebuhlungu kunye nokucaphuka zinokubakho. |
| Ukunciphisa ixesha lonyango kunye neendleko ekuhambeni kwexesha. | Eli asiloyeza eliphilisa ngokupheleleyo isifo, lilawula kuphela ukwenzeka kwesifo esibi. |
Ingaba olu nyango lufumaneka kwilizwe lethu?
Okwangoku, i-donanemab ivunyiwe eMelika kuphela. Ngoko ke kuya kuthatha ixesha elithile ukuba olu nyango lufumaneke kwizibhedlele zaseSri Lanka. Kwakhona, ibiza kancinci. Nangona kunjalo, ukuba eli yeza liza eSri Lanka kwixesha elizayo, kunokwenzeka ukuba izigulana ziya kufumana isiqabu ngokungenelela kukarhulumente kunye nomshuwalense.
Nangona kunjalo, izinto ezintsha ezifunyenweyo ezifana nezi zibonisa ukuba isayensi iqhubeka kancinci kancinci ekulweni nesifo sika-Alzheimer. Oko kusinika ithemba elikhulu.
Umyalezo Wokuya Ekhaya
- I-Donanemab liyeza elitsha elivunyiweyo kwizigaba zokuqala zesifo sika-Alzheimer.
- Oku kususa iiproteni ze-amyloid eziyingozi eziqokelelana engqondweni kwaye kucothise ukuqhubela phambili kwesi sifo.
- Kubalulekile ukuqonda ukuba oku akuyonto yokuphelisa zonke iingxaki.
- Eyona nzuzo inkulu yolu nyango kukuba lunokupheliswa xa i-amyloid isusiwe engqondweni.
- Ngenxa yokuba kunokwenzeka ukuba kubekho iimeko eziyingozi ezifana ne-ARIA, ukubekwa esweni ngokusondeleyo ngugqirha kunye ne-MRI scans kubalulekile kulo lonke ixesha lonyango.
- Ngaphambi kokuba wenze naziphi na izigqibo malunga nempilo yakho okanye yomntu omthandayo, soloko uxoxa nogqirha wakho ngazo zonke iindlela onokukhetha kuzo, iingenelo kunye neengozi.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho