Sonke besisoloko sivile ukususela ebuntwaneni ukuba i-calcium ibalulekile kumathambo aqinileyo (kuquka namazinyo). Yiyo loo nto. Kodwa ubusazi na ukuba imizimba yethu ikwafuna isixa esithile se-calcium ukugcina imithambo yegazi esempilweni, izihlunu, kunye nenkqubo yemithambo-luvo? Mhlawumbi uvavanyo lwakho lwegazi lwakutshanje lubonise ukuba inqanaba lakho le-calcium liphezulu kakhulu okanye liphantsi kakhulu. Ukuba kunjalo, ugqirha wakho unokucebisa olunye uvavanyo lwegazi olukhethekileyo. Olu luvavanyo olulinganisa inqanaba le-parathyroid hormone (PTH).

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Kutheni ugqirha ekucela ukuba wenze olu vavanyo lwe-PTH?

Ngamafutshane, le hormone ebizwa ngokuba yi-PTH yeyona nto iphambili elawula amanqanaba e-calcium emzimbeni wethu. Le hormone iveliswa ziingcongconi ezine ezincinci kakhulu entanyeni yethu. Sizibiza ezi ziingcongconi ze-parathyroid. Cinga ngayo njenge-'sensors' ezine ezincinci entanyeni yethu ezilawula amanqanaba e-calcium emizimbeni yethu. Ezi zisebenza ngolu hlobo:

Xa amanqanaba e-calcium egazini lakho ehla , la madlala akhupha i-hormone i-PTH egazini lakho. Le hormone i-PTH iya emathanjeni nasezintsoni ize ibuyisele i-calcium egazini lakho, nto leyo ebuyisela amanqanaba e-calcium kwisiqhelo.
Xa amanqanaba e-calcium egazini lakho enyuka , la madlala ayayeka ukukhupha i-PTH hormone, nto leyo ethintela ukuqokelelwa kwe-calcium ngokungeyomfuneko egazini.

Ngoku uyaqonda, akunjalo? Ukuba kukho ingxaki ngenqanaba lakho le-calcium, ugqirha wenza olu vavanyo lwe-PTH ukuze afumanise ukuba ingaba imbangela yingxaki ekusebenzeni kwamadlala e-parathyroid okanye kukho esinye isizathu.

Zithini iimpawu zokwanda nokuncipha kwe-calcium emzimbeni?

Ukuba amanqanaba akho e-calcium aqhelekanga, oko kuthetha ukuba aphezulu kakhulu (i-Hypercalcemia) okanye aphantsi kakhulu (i-Hypocalcemia), unokufumana iimpawu ezithile. Itheyibhile engasezantsi iya kukunceda ukuqonde oku ngokucacileyo.

Iimpawu ze-calcium ephezulu egazini (i-Hypercalcemia)	Iimpawu ze-calcium ephantsi egazini (i-Hypocalcemia)
Intlungu yesisu Ukoma okugqithisileyo Ukuchama rhoqo Isicaphucaphu Ukudinwa kakhulu komzimba Intlungu yemisipha Intlungu yethambo Amatye ezintso	Ukudakumba kunye nokutshintsha kweemvakalelo Ukuqaqamba kwemisipha Ukuba ndindisholo ezandleni, ezinyaweni, okanye emlonyeni Ukuphazamiseka kwentliziyo

Eyona nto ibalulekileyo kukubona ugqirha ngokukhawuleza uze ufumane ingcebiso ngaphandle kokuzama ukuzixilonga ukuba unazo ezi mpawu.

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Zithini iingenelo kunye neengozi zolu vavanyo?

Enyanisweni, olu vavanyo lwegazi lwe-PTH lulula kakhulu. Akukho sizathu sokoyika. Njengakuvavanyo lwegazi, kukho iingozi ezincinci.

Usenokuva intlungu encinci apho kufakwa khona inaliti.
Indawo isenokuba nemivumbo okanye ibuhlungu kancinci emva kovavanyo.
Kunqabile kakhulu ukuba kubekho usulelo okanye uzive ubuthathaka emva kokutsalwa igazi lakho.

Kodwa xa kuthelekiswa nale mingcipheko mincinci, iingenelo zolu vavanyo zinkulu kakhulu . Kuba olu vavanyo lunokuxelela ugqirha wakho ngqo ukuba umzimba wakho uvelisa i-PTH hormone eninzi kakhulu okanye encinci kakhulu. Lunokunceda ukuqinisekisa ukuba ingxaki ayikho kwi-parathyroid glands kwaye lukhangele ezinye izizathu zamanqanaba e-calcium angaqhelekanga.

Ulungiselela njani ngaphambi kovavanyo?

Ugqirha wakho angakucela ukuba uyeke okwethutyana ukuthatha amayeza athile okanye izongezo, ezifana neevithamini kunye ne-calcium, usuku okanye ezimbini ngaphambi kovavanyo. Nangona kunjalo, ungaze uyeke ukuthatha naliphi na iyeza ngaphandle kokubonisana nogqirha wakho kuqala. Ngokuqinisekileyo kufuneka umxelele ugqirha wakho, ingakumbi ukuba usebenzisa amayeza ezinye iimeko.

Ungaziqonda njani iziphumo?

Emva kokuba isampuli yegazi ithunyelwe kwilebhu, kungathatha iintsuku ezimbalwa ukuba iziphumo zibuye. Eli xesha linokwahluka ngokuxhomekeke kwilebhu kunye neemfuno zikagqirha wakho. Amanqanaba e-PTH adla ngokulinganiswa ngee-picograms nge-milliliter (pg/mL). Uluhlu oluqhelekileyo lunokwahluka kancinci ukusuka kwilebhu ukuya kwenye. Amanqanaba e-PTH yomntu ophilileyo adla ngokuba phakathi kwe-10-65 pg/mL. Nangona kunjalo, musa ukutsiba kwizigqibo ngokusekelwe kumanani akwiziphumo zakho zovavanyo.Ngugqirha wakho kuphela onokuthelekisa loo maxabiso namanqanaba akho e-calcium aze achaze kanye ukuba athetha ukuthini. Le theyibhile ingezantsi inika umbono wezinye zezizathu eziqhelekileyo zamanqanaba aphezulu okanye aphantsi e-PTH.

Imeko	Izizathu ezinokwenzeka
Amanqanaba e-PTH anyukileyo	I-Hyperparathyroidism Ukunqongophala kweVithamin D Isifo sezintso esingapheliyo Amanqanaba aphantsi e-calcium ngenxa yesizathu esingesiso i-parathyroid glands
Amanqanaba e-PTH anciphileyo	I-Hypoparathyroidism Utyando lwe-thyroid Unyango ngemitha Ukugqithisa isinyithi Izifo ezizikhusela ngokwazo emzimbeni Amanqanaba aphantsi e-magnesium

Ngaba kuza kubakho ezinye iimvavanyo eziza kwenziwa ngokulandelayo?

Ewe, kuxhomekeke kwiziphumo zovavanyo lwe-PTH, kusenokufuneka wenze ezinye iimvavanyo ezininzi. Kufana nomcuphi olandela umkhondo emva komnye.

Umzekelo, ukuba inqanaba lakho le-PTH liphezulu kodwa inqanaba lakho le-calcium liphantsi , oko kuthetha ukuba amadlala akho e-parathyroid ayasebenza, kodwa ngesizathu esithile amanqanaba akho e-calcium awanyuki. Ugqirha wakho unokujonga amanqanaba akho e-vitamin D, i-phosphorus, kunye ne-magnesium.

Kwelinye icala, ukuba inqanaba lakho le-calcium liphezulu kwaye inqanaba lakho le-PTH liphezulu , usenokuba une-hyperparathyroidism. Ugqirha wakho uya kwenza uvavanyo lwe-X-ray okanye olunye uvavanyo lokujonga imifanekiso ukujonga amadlala akho e-parathyroid. Basenokujonga nokudumba okanye iithumba.

Unyango lwale meko lutyando lokususa i-gland. Nangona kunjalo, ukuba imeko ayinzima kangako, okanye ukuba akukho zimpawu zibalulekileyo ezifana nokonakala kwezintso okanye ubuthathaka bamathambo, ugqirha wakho unokukunika amayeza (afana neCinacalcet (Sensipar) aze akuvumele ukuba ujonge amanqanaba akho e-calcium kunye ne-PTH rhoqo .

Umyalezo Wokuya Ekhaya

Uvavanyo lwegazi lwe-PTH luvavanyo olubaluleke kakhulu lokufumanisa unobangela wamanqanaba e-calcium angaqhelekanga egazini lakho.
Olu luvavanyo lwegazi olulula kakhulu, olungenamngcipheko uphezulu, ngoko ke musa ukuloyika ngokungeyomfuneko.
Ngaphambi kovavanyo, xelela ugqirha wakho malunga namayeza okanye izongezo ozithathayo. Musa ukuyeka ukuthatha nawaphi na amayeza ngaphandle kwengcebiso kagqirha.
Wakuba ufumene iziphumo zovavanyo lwakho, thetha nogqirha wakho malunga nentsingiselo yezo xabiso kunye namanyathelo alandelayo omawuwathathe.