Izinto ekufuneka uzazi ngeSifo sikaParkinson!

Ngaba ngamanye amaxesha ukhe ucinge ngezifo eziza nokwaluphala? Esinye sezifo ezinjalo sisifo sikaParkinson. Usenokuba ukhe weva ngaso. Nangona sisimo esibi kakhulu, kubaluleke kakhulu ukuba usiqonde ngokuchanekileyo . Ngoko ke namhlanje, masithethe ngesifo sikaParkinson, indlela esikhula ngayo, zithini iimpawu, kwaye ingaba kukho unyango.

Yintoni isifo sikaParkinson? Ngamafutshane...

Ngamafutshane, isifo sikaParkinson sisifo apho iindawo ezithile zobuchopho bakho ziba buthathaka kancinci kancinci, kwaye iimpawu ziya zisiba mandundu ngokuhamba kwexesha. Uninzi lwabantu luyasazi esi sifo kuba sichaphazela ulawulo lwezihlunu, ukuhamba, ukulinganisela, kunye nokuhamba. Kodwa sinokuchaphazela nezinye izinto ezininzi, kubandakanya iimvakalelo zakho, ukucinga, kunye nempilo yengqondo. Njengomatshini wokwaluphala, iindawo ezithile zobuchopho bakho ziyayeka ukusebenza kakuhle.

Ngubani ochaphazeleka kakhulu sesi sifo?

Umngcipheko wokuba nesifo sikaParkinson uyanda xa ukhula. Ubudala obuqhelekileyo bokuqala kwesi sifo bumalunga neminyaka engama-60. Kubonakala ngathi sixhaphake kancinci kumadoda kunakubafazi.

Nangona kunjalo, nangona kudla ngokunxulunyaniswa nobudala, ngamanye amaxesha inokuvela nakubantu abadala abaselula, njengabo bakwiminyaka yabo yama-20. Nangona kunjalo, ayiqhelekanga kakhulu. Ukuba umntu oselula uyayifumana, kusenokwenzeka ukuba umzali, umnakwabo, udade wabo, okanye umntwana waloo mntu naye unesifo.

Ixhaphake kangakanani isifo sikaParkinson?

Isifo sikaParkinson sisifo esixhaphakileyo kunokuba unokucinga. Sesesibini isifo esixhaphakileyo se-neurodegenerative ebuchotsheni xa ukhula. Sikwasisifo esixhaphakileyo se-motor brain. Iingcali ziqikelela ukuba ubuncinci i-1% yabantu abangaphezu kweminyaka engama-60 kwihlabathi liphela banaso esi sifo.

Esi sifo sichaphazela njani umzimba wakho?

Isifo sikaParkinson sibangela ukuba indawo ethile yobuchopho bakho ebizwa ngokuba yi-basal ganglia ibuthathaka kancinci kancinci. Njengoko le ndawo ibuthathaka, kancinci kancinci uyalahlekelwa ngamandla okuyilawula. Abaphandi bafumanise ukuba isifo sikaParkinson sibangela utshintsho olukhulu kwikhemistri yengqondo yakho.

Ngokwesiqhelo, ingqondo yakho isebenzisa iikhemikhali ezibizwa ngokuba zii-neurotransmitters ukulawula indlela iiseli zobuchopho (ii-neurons) ezinxibelelana ngayo. Xa unesifo sikaParkinson, ingqondo yakho ayinayo enye yezi neurotransmitters eyaneleyo, ikhemikhali ephambili ebizwa ngokuba yi-dopamine .

Xa ingqondo yakho ithumela imiqondiso kwizihlunu zakho ukuba zishukume, ezo ntshukumo zilungiswa kakuhle kusetyenziswa iiseli ezifuna i-dopamine. Xa i-dopamine iphantsi, iimpawu eziphambili zesifo sikaParkinson kukuhamba kancinci kunye nokungcangcazela.

Njengoko isifo sikaParkinson siqhubeka, iimpawu ziya zisanda kwaye zibe nzima. Kwizigaba zokugqibela zesi sifo, ukusebenza kwengqondo kuyachaphazeleka, okukhokelela kwiimpawu ezifana ne-dementia kunye neemeko ezifana nokudakumba.Inokwenzeka loo nto.

Yintoni umahluko phakathi kwesifo sikaParkinson kunye nesifo sikaParkinson?

Igama elithi "Parkinsonism" ligama eliqhelekileyo eliquka isifo sikaParkinson kunye nezinye iimeko ezininzi ezineempawu ezifanayo. Oko kukuthi, eli gama lingasetyenziswa kungekuphela nje kwisifo sikaParkinson, kodwa nakwezinye iimeko ezifana neMultiple System Atrophy okanye iCorticobasal Degeneration . Ngamafutshane, iParkinsonism ifana nesambrela esikhulu, kwaye isifo sikaParkinson sesinye sezifo eziphantsi kweso sambrela.

Zithini iimpawu zesifo sikaParkinson?

Iimpawu ezaziwayo zesifo sikaParkinson zezo zinxulumene nokungakwazi ukulawula izihlunu. Nangona kunjalo, iingcali ngoku ziyazi ukuba iingxaki zokulawula izihlunu azizo zodwa iimpawu zesifo.

Iimpawu ezinxulumene nemoto

Ezi zibizwa ngokuba ziimpawu zentshukumo yomzimba, oko kukuthi ezo zinxulumene nokuhamba.

• Ukucotha kokuhamba (Bradykinesia): Olu luphawu olufunekayo ukuze kufunyanwe isifo sikaParkinson. Abantu abanale meko banokuchaza izihlunu zabo njengezibuthathaka, kodwa eneneni yingxaki yokulawula izihlunu, kungekhona ukulahlekelwa ngamandla. Kufana nokuba amalungu akho omzimba abambekile, kwaye kufuneka usebenze kancinci.
• Ukungcangcazela kokuphumla: Oku kungcangcazela okunesingqi okwenzekayo nokuba izihlunu azisetyenziswa. Kwenzeka kubantu abamalunga nama-80% abaneParkinson's. Oku kwahlukile kwimeko ebizwa ngokuba yi- essential tremor . Kwi-essential tremor, izihlunu azidli ngokungcangcazela xa ziphumle.
• Ukuqina okanye ukuqina kwemisipha: Ukuqina kwe-lead-pipe kunye nokuqina kwe-cogwheel ziimpawu eziqhelekileyo zesifo sikaParkinson. Ukuqina kwe-lead-pipe kukuqina okuqhubekayo, okungaguqukiyo okwenzeka xa inxalenye yomzimba ishukunyiswa. Ukuqina kwe-cogwheel kwenzeka xa kunyikima kunye nokuqina kwe-lead-pipe zidityanisiwe. Ifumana igama layo kuba iintshukumo zibonakala zishukuma kwaye ziyema (cinga ngayo njengesandla sesibini kwiwotshi endala).
• Ukuma okungazinzanga okanye ukuhambahamba: Ukucotha nokuqina kwentshukumo, okubangela ukuma okugobileyo nokugobileyo. Oku kudla ngokubonakala njengoko isifo siqhubeka. Oku kuyaphawuleka xa umntu ehamba, njengoko ehamba ngamanyathelo amancinci kwaye engashukumisi iingalo zakhe kakhulu. Kwakhona kufuneka athathe amanyathelo aliqela xa ejika.

Kusenokubakho nezinye iimpawu ezinxulumene nezinye iintshukumo:

• Ukuncipha kokuqhwanyaza kwamehlo rhoqo: Oku kukwaluphawu lokuncipha kolawulo lwemisipha yobuso.
• Ukubhala ngesandla okuncinci, okukrwelwe phezulu (Micrographia): Oku kubangelwa ziingxaki zokulawula izihlunu.
• Ukuvuza amathe: Oku kukwabangelwa kukulahlekelwa kulawulo lwemisipha yobuso.
• I-Hypomimia: Oku kuthetha ukuba imbonakalo yobuso ayitshintshi kangako, okanye ayitshintshi kwaphela.
• Ubunzima bokuginya (iDysphagia): Oku kubangelwa kukulahlekelwa lulawulo kwimisipha emqaleni. Oku kwandisa umngcipheko weengxaki ezifana ne-pneumonia okanye ukukrwitshwa.
• Ilizwi eliphantsi ngendlela engaqhelekanga (i-Hypophonia): Oku kubangelwa kukungalawuleki kakuhle kwemisipha emqaleni nasesifubeni.

Iimpawu ezingezizo ezokuhamba kwemisipha

Kukwakho neempawu ezininzi ezingahambelaniyo nokunyakaza kunye nolawulo lwemisipha. Ngaphambili, iingcali zazicinga ukuba ezi mpawu zokungashukumi, ukuba zivele ngaphambi kweempawu ezinxulumene nokuhamba, zizinto ezibangela umngcipheko wesifo. Nangona kunjalo, ngoku kukho ubungqina obandayo bokuba ezi mpawu zinokuvela nakwizigaba zokuqala zesifo. Oku kuthetha ukuba ezi mpawu zinokuba ziimpawu ezilumkisayo ezandulela iimpawu ezinxulumene nokuhamba ngeminyaka, kwanamashumi eminyaka.

Iimpawu ezingahambelaniyo nentshukumo (ezinokuba zizibonakaliso zesilumkiso kwangethuba zigqanyiswe ngombala ongqindilili ):

• Iimpawu zenkqubo yemithambo-luvo ezizimeleyo: Ezi ziquka i-orthostatic hypotension , ukuqhina kunye neengxaki zesisu, ukungakwazi ukuzibamba komchamo, kunye nokungasebenzi kakuhle ngokwesondo.
• Uxinzelelo.
• Ukulahlekelwa yimvakalelo yokuvumba (anosmia).
• Iingxaki zokulala: Imizekelo ibandakanya ukuphazamiseka kwentshukumo yamalungu rhoqo (i-PLMD) , ukuphazamiseka kokuziphatha kwentshukumo yamehlo ngokukhawuleza (i-REM), kunye nesifo semilenze esingenakuphumla.
• Ubunzima bokucinga nokugxila (i-Parkinson's-related dementia).

Ngaba kukho amanqanaba esifo sikaParkinson?

Isifo sikaParkinson singathatha iminyaka, kwanamashumi eminyaka, ukuba sibangele iimpawu ezinzulu. Ngo-1967, iingcali ezimbini ezibizwa ngokuba nguMargaret Horn noMelvin Yar baphuhlisa inkqubo yokwahlulahlula isifo sikaParkinson. Nangona kunjalo, loo nkqubo yokwahlulahlula ayisasetyenziswa kakhulu. Endaweni yokwahlulahlula isifo, kuluncedo ngakumbi ukufumanisa indlela esi sifo esichaphazela ngayo umntu ngamnye ngokwahlukeneyo kwaye sibaphathe ngokufanelekileyo.

Okwangoku, iMovement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) yeyona ndlela iphambili esetyenziswa ngoogqirha ukwahlula esi sifo. I-MDS-UPDRS ilinganisa iinkalo ezine ezahlukeneyo zendlela esikuchaphazele ngayo isifo sikaParkinson:

• Inxalenye 1: Izinto ezingezizo ezokuhambahambayo kumava obomi bemihla ngemihla.Eli candelo lijonga iimpawu ezinxulumene nempilo yengqondo kunye namandla engqondo, ezinje nge-dementia, ukudakumba, kunye nexhala, ezingahambelaniyo nokunyakaza. Likwabuza imibuzo malunga nezinto ezifana nentlungu, ukuqhina, ukungakwazi ukuzibamba komchamo, kunye nokudinwa.
• Icandelo lesi-2: Iinkalo ezinxulumene nentshukumo yamava obomi bemihla ngemihla. Eli candelo lijonga impembelelo kwimisebenzi kunye nezakhono ezinxulumene nentshukumo. Oku kuquka izinto ezifana nokukwazi ukuthetha, indlela yokutya, ukuhlafuna, nokuginya, nokuba ungazinxiba na, ukuhlamba, kunye nokuba unesithukuthezi.
• Icandelo lesi-3: Uvavanyo lokushukuma. Ugqirha usebenzisa le nxalenye ukufumanisa iziphumo ezinxulumene nokushukuma kwesifo sikaParkinson. Ezi mvavanyo zilinganisa izinto ezifana nentetho yakho, imbonakalo yobuso, ukuqina, indlela yokuhamba kunye nesantya, ukulinganisela, isantya sokushukuma, kunye nokungcangcazela.
• Icandelo 4: Iingxaki zokushukuma. Eli candelo kulapho ugqirha wakho agqiba khona ukuba iimpawu zakho zeParkinson zibuchaphazela kangakanani ubomi bakho. Oku kuquka ixesha onalo iimpawu ezithile ngosuku kunye nokuba ziyayichaphazela na indlela ochitha ngayo ixesha lakho.

Yintoni ebangela esi sifo?

Nangona kuye kwachongwa izinto ezininzi ezinokubangela isifo sikaParkinson (umzekelo, ukuchatshazelwa zizibulali-zinambuzane), unobangela oqinisekisiweyo kuphela ziimpembelelo zemfuza. Xa isifo sikaParkinson singesiso imfuza, iingcali zisibeka "njengesi-idiopathic." Oku kuthetha ukuba abazi ukuba kutheni sikhula.

Kwiimeko ezininzi, kunzima ukufumana unobangela othile wesifo sikaParkinson, kodwa uphando luyaqhubeka.

Isifo sikaParkinson sosapho

Isifo sikaParkinson sinokungena kwiintsapho. Oku kuthetha ukuba ungasifumana njengelifa kumzali omnye okanye bobabini. Nangona kunjalo, oku kuthetha malunga ne-10% yazo zonke iimeko. Iingcali zichonge ubuncinane iijini ezisixhenxe ezinxulumene nesifo sikaParkinson.

Isifo sikaParkinson esingaqhelekanga

Iingcali zikholelwa ukuba isifo sikaParkinson, esingaziwayo, sibangelwa ziingxaki kwindlela umzimba wakho osebenzisa ngayo iproteni ebizwa ngokuba yi-alpha-synuclein . Iiproteni ziimolekyuli zeekhemikhali ezinemilo ethile. Xa ezinye iiproteni zilahlekelwa yimilo yazo echanekileyo - oku kubizwa ngokuba yi-protein misfolding - umzimba wakho awukwazi ukuzisebenzisa okanye ukuziqhekeza.

Ngenxa yokuba kungekho ndawo yokuya kuyo, ezi proteni ziqokelelana kwiindawo ezahlukeneyo okanye kwezinye iiseli (ezi proteni ziyahlangana kwaye zenze ii-aggregates ezibizwa ngokuba yi-Lewy bodies ). Ukuqokelelana kwezi mizimba ze-Lewy kubangela iziphumo ezinobuthi kwiiseli kwaye zizonakalisa. Oku kudibana kwezi proteni kubonakala kwizifo ezininzi, ezifana nesifo se-Alzheimer kunye nesifo sikaHuntington .

Ukuphazamiseka kwengqondo okubangelwa yi-parkinsonism

Kukho ezinye iimeko okanye izizathu ezinxulunyaniswa neParkinsonism. Nangona ezi zingafani nesifo sikaParkinson, zineempawu ezifanayo, ngoko oogqirha baqwalasela ezi zizathu xa befumanisa isifo sikaParkinson.

• Amayeza: Amanye amayeza anokubangela iziphumo ezifana neParkinson's. Ezi ziphumo zihlala zizezexeshana ukuba iyeza liyekiwe.
• I-Encephalitis: Ukudumba kwengqondo, okwaziwa ngokuba yi -encephalitis, ngamanye amaxesha kunokubangela i-Parkinsonism.
• Iityhefu: Ukuchatshazelwa zizinto ezifana nothuli lwe-manganese, i-carbon monoxide, umsi wokudibanisa, kunye nezinye izibulali-zinambuzane nazo zinokubangela isifo sikaParkinson.
• Ukulimala kwengqondo okubangela ingozi: Ukulimala entloko okuphindaphindiweyo ngenxa yemidlalo efana nebhokisi, ibhola ekhatywayo, kunye nehoki kunokubangela umonakalo engqondweni. Oku kubizwa ngokuba yi-"post-traumatic parkinsonism."

Ingaba esi sisifo esosulelayo?

Hayi, isifo sikaParkinson asisuleli. Awunakuyifumana komnye umntu.

Indlela yokuxilonga esi sifo?

Ukuchonga isifo sikaParkinson kudla ngokuba yinkqubo yezonyango. Oku kuthetha ukuba ugqirha uya kufumanisa isifo ngokujonga iimpawu zakho, abuze imibuzo, aze ahlole imbali yakho yezonyango. Kunokwenziwa ezinye iimvavanyo zokuxilonga nezelebhu, kodwa zihlala zifuneka ukuze kuthintelwe ezinye iimeko okanye izizathu.

Ngaphandle kokuba awuphenduli kunyango lwesifo sikaParkinson, mhlawumbi awudingi vavanyo oluninzi lwelabhoratri. Ukuba awuphenduli, oko kungabonisa ukuba unenye imeko.

Zeziphi iimvavanyo ezisetyenziswayo ukufumanisa isifo?

Xa oogqirha bekrokrela ukuba isifo sikaParkinson sikhona okanye kufuneka baqinisekise ukuba akukho ezinye izifo, banokuyalela iintlobo ngeentlobo zovavanyo lokujonga kunye nokuxilongwa. Ezinye zezi ziquka:

• Uvavanyo lwegazi (oku kunceda ekuqinisekiseni ukuba akukho ezinye iintlobo zeParkinson's).
• I-CT scan eqikelelweyo.
• Uvavanyo lwemfuza.
• I-MRI (i-magnetic resonance imaging).
• Iskeni se-Positron emission tomography (PET).

Kukwakho novavanyo olutsha lwelebhu.

Abaphandi bafumene iindlela zokufumanisa ezinye zeempawu zesifo sikaParkinson. Zombini ezi mvavanyo zintsha zinxulumene neproteni i-alpha-synuclein, kodwa bazivavanya ngendlela entsha nengaqhelekanga.

• Ukubhoboza umqolo/umqolo: Olu vavanyo lujonga iiproteni ze-alpha-synuclein ezigobileyo kwi-cerebrospinal fluid ezijikeleze ingqondo kunye nomqolo.
• I-biopsy yolusu:Olunye uvavanyo lubandakanya ukuthatha isampuli yezicubu zemithambo-luvo (i-biopsy) kumphezulu wolusu lwakho. Oku kunokujonga ukuba unesiphene kwiproteni ye-alpha-synuclein eyonyusa umngcipheko wakho wokuba nesifo sikaParkinson.

Inyangwa njani? Ngaba inganyangeka ngokupheleleyo?

Okwangoku, isifo sikaParkinson asinakunyangwa ngokupheleleyo. Nangona kunjalo, zininzi iindlela zokulawula iimpawu zaso. Unyango lunokwahluka kumntu nomntu, kuxhomekeke kwiimpawu zabo kunye nendlela unyango olusebenza ngayo. Amayeza yeyona ndlela iphambili yokunyanga esi sifo.

Unyango lwesibini kukwenza utyando lokufakela isixhobo esihambisa umbane othambileyo kwinxalenye yengqondo yakho (oku kubizwa ngokuba yiDeep Brain Stimulation). Kukwakho nezinye iindlela ezisekelwe kuphando, ezifana nonyango olusekelwe kwiiseli ze-stem, kodwa azifumaneki kuwo wonke umntu.

Ngawaphi amayeza kunye nonyango olusetyenziswayo?

Unyango lwamayeza kwisifo sikaParkinson lwahlulwe kwiindidi ezimbini eziphambili: unyango oluthe ngqo kunye nonyango oluneempawu. Unyango oluthe ngqo lujolise kwisifo sikaParkinson ngokwaso. Unyango oluneempawu lunyanga kuphela ezinye zeziphumo zesifo.

Amayeza

Amayeza okunyanga isifo sikaParkinson asebenza ngeendlela ezahlukeneyo.

• Ukongezwa kweDopamine: Amayeza afana neLevodopa anokunyusa ubungakanani bedopamine engqondweni yakho. Eli yeza lihlala lisebenza. Ukuba alisebenzi, lihlala liluphawu lwesinye isifo sikaParkinson, hayi sikaParkinson. ILevodopa inokuba nemiphumo emibi xa isetyenziswa ixesha elide, kwaye ukusebenza kwayo kunokuncipha.
• Isenzo esifana ne-dopamine: Ii-dopamine agonists ngamayeza aneziphumo ezifana ne-dopamine. Adla ngokunikwa izigulana eziselula ukuze zilibazise ukuqala kwe-levodopa.
• Izithinteli zeDopamine: Umzimba wakho uneenkqubo zendalo eziqhekeza ii-neurotransmitters ezifana ne-dopamine. Amayeza athintela oku kuphazamiseka anokunceda ukugcina i-dopamine engaphezulu engqondweni.
• Izithinteli zeLevodopa: La mayeza anciphisa isantya umzimba wakho osebenza ngaso iLevodopa, nto leyo evumela ukuba isebenze ixesha elide.
• Amayeza okuthintela i-Adenosine: Amayeza athintela indlela ezinye iiseli ezisebenzisa ngayo i-adenosine anokuba nefuthe elongezelelweyo xa enikwa ne-levodopa.

Kukwakho namayeza amaninzi anyanga iimpawu ezithile zesifo sikaParkinson. Umzekelo:

• Ukuziphatha okubi ngokwesondo.
• Ukudinwa okanye ukozela.
• Ukuqhinwa.
• Iingxaki zokulala.
• Uxinzelelo.
• Isifo sengqondo esixhalabisayo.
• Ixhala.
• Ukuphupha izinto ezingekhoyo kunye nezinye iimpawu zengqondo.

Ukuvuselelwa Kobuchopho Obunzulu

Ngaphambili, bekukho utyando olwalulimaza ngabom kwaye lubangela amanxeba kwinxalenye yengqondo eyayingasebenzi kakuhle ngenxa yesifo sikaParkinson. Namhlanje, umphumo ofanayo unokufezekiswa ngeDeep Brain Stimulation . Kule nto, isixhobo esifakwe emzimbeni sihambisa umbane othambileyo kuloo nxalenye yengqondo.

Eyona nzuzo inkulu yoku kukuba iDeep Brain Stimulation iyaguqulwa. Nangona kunjalo, amanxeba angabom awanakujikwa.

Unyango lovavanyo

Abaphandi bahlola ezinye iindlela zonyango ezinokunceda kwisifo sikaParkinson, kubandakanya ukufakelwa kweeseli ze-stem , unyango lokulungisa ii-neuron , kunye nonyango lwe-gene .

Ndingazilawula njani iimpawu zam ukuba andizinyamekeli?

Isifo sikaParkinson asisosifo onokusixilonga ngokwakho. Musa ukuzama ukulawula iimpawu zakho ngaphandle kokuthetha nogqirha.

Ndiza kuziva ngcono ngokukhawuleza kangakanani emva konyango?

Oku kuxhomekeke kwizinto ezininzi, njengohlobo lonyango kunye nobunzima besifo. Ugqirha wakho ngumntu ofanelekileyo ukukunika ulwazi malunga noku.

Ndingalindela ntoni ukuba ndinesi sifo?

Isifo sikaParkinson sisifo esibangela ukuwohloka kwengqondo. Oku kuthetha ukuba iziphumo zengqondo ziya ziba mandundu ngokuhamba kwexesha. Nangona kunjalo, kudla ngokuthatha ixesha ukuba esi sifo sibe mandundu. Uninzi lwabantu lunokuphila ubomi obuqhelekileyo ngesi sifo.

Kwinqanaba lokuqala, ungadinga uncedo oluncinci kwaye ukwazi ukuphila ngokuzimela. Njengoko iziphumo ziba mandundu ngakumbi, ungadinga amayeza okulawula iimpawu zakho. Amayeza amaninzi, ingakumbi iLevodopa, asebenza kancinci okanye kakhulu xa ufumana idosi ephantsi esebenza kwiimpawu zakho.

Isifo sikaParkinson sihlala ixesha elingakanani?

Ngenxa yokuba isifo sikaParkinson asinakunyangwa, sisifo esihlala ixesha elide, esihlala ubomi bonke.

Iyintoni imbonakalo yesifo sikaParkinson?

Isifo sikaParkinson asibulali. Nangona kunjalo, iimpawu kunye nemiphumo ngamanye amaxesha inokuba yingozi. Nangona kunjalo, ngenxa yokuqhubela phambili kunyango, ixesha lokuphila kwabantu abanesi sifo linyuke kakhulu.

Ndingawunciphisa okanye ndiwuthintele njani umngcipheko wokufumana esi sifo?

Isifo sikaParkinson sibangelwa zizinto zemfuza okanye sisiganeko esingalindelekanga. Akukho nanye kwezi zinto enokuthintela, kwaye umngcipheko awunakuncitshiswa. Nangona abantu abasebenza kwezolimo okanye kwezokudityaniswa kwentsimbi kuthiwa basengozini enkulu, ayinguye wonke umntu ofumana isifo sikaParkinson.

Ndingazinyamekela njani?

Ukuba unesifo sikaParkinson, eyona nto ingcono onokuyenza kukuzinyamekela njengoko ugqirha wakho ecebisa.

• Sela amayeza akho njengoko kuyalelwe: Ukusela amayeza akho ngokuchanekileyo kunokwenza umahluko omkhulu kwiimpawu zikaParkinson.
• Bona ugqirha wakho njengoko kucetyisiwe: Ezi ntlanganiso zibaluleke kakhulu ukulawula imeko yakho nokufumana amayeza afanelekileyo kunye nomlinganiselo.
• Musa ukuzityeshela iimpawu: Isifo sikaParkinson sinokubangela iimpawu ezahlukeneyo. Uninzi lwazo lunokunyangeka.

Imibuzo ebuzwa rhoqo (FAQ)

Umntu ufumana njani isifo sikaParkinson?

Iingcali aziyazi imbangela yesifo sikaParkinson. Malunga ne-10% yamatyala abangelwa yimfuza. Ama-90% aseleyo awanazo iimpawu ezingaqhelekanga.

Ziziphi iimpawu zokuqala zesifo sikaParkinson?

Iimpawu zokuqala zinokuba kukuhamba kancinci komzimba (ukungcangcazela, ukungcangcazela, ukuqina komzimba) okanye ukungabi nakuhamba komzimba. Iimpawu ezingezizo ezokuhamba komzimba (umz., ukuphelelwa livumba (i-anosmia) , ukuqhinwa , iingxaki zokulala , uxinzelelo lwegazi oluphantsi ) zisenokuqala kwiminyaka ngaphambi kokuba kuvele iimpawu zokuhamba komzimba.

Ngaba isifo sikaParkinson siyabulala?

Hayi, isifo sikaParkinson asibulali sodwa. Nangona kunjalo, sinokubangela ezinye izifo ezinokubangela ukufa.

Ngaba isifo sikaParkinson sinokunyangwa?

Hayi, isifo sikaParkinson asinakunyangeka. Nangona kunjalo, sinokunyangwa, kwaye unyango oluninzi lusebenza kakuhle. Kusenokwenzeka nokuba kuncitshiswe ukuqhubela phambili kwesi sifo kunye nokuqala kweempawu ezinzima.

Okokugqibela, yintoni ekufuneka uyikhumbule (Umyalezo Wokuya Ekhaya)

Isifo sikaParkinson sisifo esibi kakhulu nesihlala ixesha elide, kodwa akukho nto yokoyika. Ngonyango lwangoku, abantu abaninzi banokukwazi ukulawula iimpawu zabo kakuhle baze baphile ubomi obuqhelekileyo.

Eyona nto ibalulekileyo kukufuna ingcebiso kagqirha ngokukhawuleza ukuba wena okanye umntu osondeleyo kuwe unezi mpawu. Okukhona isifo sifunyanwa ngokukhawuleza kwaye unyango luqala, kokukhona iziphumo ziba ngcono. Kukwabaluleke kakhulu ukulandela imiyalelo kagqirha ngokuchanekileyo.

Ukuba uneminye imibuzo malunga noku, ungathandabuzi ukuthetha nogqirha wakho. Baya kukuvuyela ukukunceda.

` Isifo sikaParkinson, izifo zobuchopho, izifo zemithambo-luvo, iingxaki zokunyakaza, i-dopamine, i-levodopa, impilo yokwaluphala