Ngaba uyazi nge-peritoneal carcinomatosis? Makhe sithethe ngayo!

Ngaba ngamanye amaxesha uziva ungakhululekanga esiswini, ukudumba, okanye iintlungu zesisu? Ezi mpawu ziqhelekile kakhulu, kwaye ngamanye amaxesha zinokubangelwa yinto esiyityayo okanye esiyiselayo, okanye kwanosulelo oluncinci. Nangona kunjalo, ngamanye amaxesha kunokubakho into enzulu ngakumbi emva kwazo efuna ingqalelo. Yiyo loo nto i -peritoneal carcinomatosis . Igama lisenokuvakala liyinkimbinkimbi kancinci, kodwa masithethe ngalo ngokulula kwaye siliqonde.

Yintoni iPeritoneal Carcinomatosis?

Ngamafutshane, oku kuthetha ukuba umhlaza oqale kwenye indawo emzimbeni wethu usasazeke waya kwi-membrane ebizwa ngokuba yi-peritoneum . Ngoku usenokuba uzibuza ukuba yintoni le peritoneum. Yi-membrane encinci ejikeleze ngaphakathi kwesisu sethu, oko kukuthi, umngxuma wesisu kunye nomngxuma we-pelvic. Amalungu aliqela angaphakathi, njengamathumbu ethu, isibindi, kunye nesisu, agqunywe yile membrane.

Ngoko ke, xa umhlaza ukhula kwenye ilungu, umzekelo, kwi-ovary okanye kwi-colon, kwaye ezo seli zomhlaza ziza kwi-peritoneum kwaye zenze ii-tumor ezintsha apho, sizibiza ngokuba yi-peritoneal carcinomatosis . Oku kwahlukile kumhlaza we-peritoneal oyintloko, oqala kwi-peritoneum ngokwayo, kuba kule meko umhlaza uqala kwenye indawo.

Olu hlobo lomhlaza lukwabizwa ngokuba ngumhlaza wesigaba samva nje okanye umhlaza osasazekayo . Yinyani leyo, olu hlobo lomhlaza luyingozi ngakumbi kunemihlaza yesigaba sangaphambi kwexesha. Kodwa ungakhathazeki. Ngonyango olutsha olufumanekayo, kunokwenzeka ukulawula ukusasazeka kwesi sifo nokunceda isigulana siphile ixesha elide.

Zeziphi iintlobo zomhlaza ezidla ngokubangela le meko?

Phantse nawuphi na umhlaza unokusasazeka uye kwi-peritoneum, kodwa ezi ntlobo zilandelayo zomhlaza zinokubangela esi sifo:

• Umhlaza wesibeleko (lo ngowona uxhaphakileyo)
• Umhlaza wamathumbu amakhulu
• Umhlaza wesisu
• Umhlaza wePancreatic
• Umhlaza wesihlomelo
• Umhlaza wamathumbu

Ziziphi iimpawu zePeritoneal Carcinomatosis?

Ixesha elininzi, le meko ayibangeli zimpawu de ichaphazele indawo enkulu ye-peritoneum. Oko kukuthi, iimpawu ziqala ukubonakala emva kokuba isifo sisasazeke kancinci. Xa oku kusenzeka, uphawu oluqhelekileyo kukuqokelelwa kolwelo esiswini (ascites) . Kulapho isisu siqala ukudumba ngendlela engaqhelekanga.

Kusenokubakho nezinye iimpawu ezininzi ezinxulumene noku:

• Ukudinwa rhoqo
• Isisu esidumbileyo ( ngenxa yokugcina ulwelo)
• Intlungu zesisu
• Ubunzima besisu
• Intlungu esezantsi yomqolo
• Isicaphucaphu nokuhlanza
• Ukuqhinwa
• Ukwehla kobunzima okanye ukutyeba okungachazekiyo

Ngoku, khangela, uninzi lwezi mpawu zixhaphakile nakwezinye izifo eziqhelekileyo. Umzekelo, iintlungu zesisu zinokubakho nakwi-gastritis. Ngoko ke, ngenxa yokuba unezi mpawu, ungoyiki uze ucinge ukuba unesi sifo sibi kakhulu. Nangona kunjalo, ukuba uqhubeka unazo ezi mpawu, kububulumko ukubona ugqirha uze uhlolwe. Kuba ngugqirha kuphela onokuqinisekisa ukuba lo ngumhlaza okanye akunjalo.

Yintoni ebangela oku?

I-Peritoneal carcinomatosis iyenzeka, njengoko bekutshiwo ngaphambili, xa umhlaza ovela kwelinye icala lomzimba usasazeka uye kwi-peritoneum. Ngokuqhelekileyo, lo mhlaza uqala ngaphakathi esiswini, kwilungu elikufutshane ne-peritoneum. Umzekelo, ii-ovari okanye i-colon.

Nangona kunjalo, malunga neshumi ekhulwini (10%) lamatyala, lo mhlaza uqala kwilungu elingaphandle kwesisu. Kwimeko enjalo, iiseli zomhlaza zihamba ngegazi okanye ngenkqubo ye-lymphatic ukuze zifikelele kwi-peritoneum. Cinga ngayo njengeziqwenga ezincinci zothuli ezihamba emlanjeni wamanzi, ezi seli zihamba nangolwelo lomzimba.

Sifunyaniswa njani esi sifo? (Ukuxilongwa)

Oogqirha basebenzisa iimvavanyo ezininzi ukufumanisa le meko. Ezinye zazo zezi:

• Uvavanyo lokufota: Olu luquka ii-CT scans , ii-MRI scans , kunye nee-PET scans . Olu hlobo lwee-scans lunokunika umfanekiso ocacileyo wokuba umhlaza usasazeke kangakanani ukuya kwi-peritoneum kunye nendawo okhoyo kuyo.
• Uvavanyo lwegazi: Igazi lakho lihlolwa iiproteni ezikhethekileyo ezibizwa ngokuba zii-tumor markers . Ezinye iiseli zomhlaza ziyazikhupha ezi zinto egazini. Amanqanaba aphezulu ezi zinto angaba luphawu lwesifo.
• I-Paracentesis: Ukuba unolwelo esiswini sakho (i-ascites), ugqirha wakho angathabatha isampuli encinci yolwelo aze aluvavanye kwilebhu. Oku kunokunceda ekuqinisekiseni ukuba loluphi uhlobo lomhlaza olusasazekileyo, okanye ukuba loluphi umhlaza oyintloko.
• I-Biopsy: Oku kuquka ukuthatha iqhekeza elincinci kakhulu lethumba uze ulihlolisise phantsi kwe-microscope ukuze ubone ukuba kukho iiseli zomhlaza na. Olu lolona vavanyo lunokubonisa ngokuqinisekileyo ukuba ngumhlaza okanye akunjalo.

Yintoni iPeritoneal Carcinomatosis Index (PCI)?

Le PCI sisixhobo esibalulekileyo kwinkqubo yokuxilonga esinceda oogqirha bacebe unyango. Besebenzisa olu luhlu, oogqirha bakunika amanqaku asekelwe ekubeni zingakanani kwaye zingakanani iiseli zomhlaza esiswini sakho nakwithumbu elincinci.

Olu lwazi lunokunceda ugqirha aqonde aze afumane umbono wokuba utyando lungazisusa ngokupheleleyo na ezi thumba.

Zithini iindlela zokunyanga oku? (Unyango)

Unyango oluphambili noluqhelekileyo lwe-peritoneal carcinomatosis lunyango olubizwa ngokuba yi -Hyperthermic Intraperitoneal Chemotherapy (HIPEC) oludityaniswe notyando lwe-cytoreductive (CRS) .

Nangona oku kungabonakala ngathi libinzana elinzima elinamagama amabini, kodwa lithetha ngolu hlobo:

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* I-CRS (Utyando lweCytoreductive): Injongo yolu tyando kukususa zonke iithumba zomhlaza ezibonakalayo kwi-peritoneal membrane.

* I-HIPEC (Hyperthermic Intraperitoneal Chemotherapy): Le ndlela isetyenziselwa ukutshabalalisa naziphi na iiseli zomhlaza eziseleyo ezincinci kakhulu ukuba zingabonwa ngamehlo emva kotyando lwe-CRS. Kule ndlela, amayeza e-chemotherapy ashushu afakwa ngqo esiswini, ashiywe endaweni yawo okwethutyana, aze asuswe. Ngenxa yokuba amayeza ashushu aze ahanjiswe ngqo kumhlaza, isebenza ngakumbi kune-chemotherapy yesiqhelo.

Olu nyango lwe-CRS kunye ne-HIPEC lunikwa ukongeza kunyango olunikwa ilungu apho umhlaza waqala khona.

Ngamanye amaxesha, ayinguye wonke umntu onokwenza utyando lwe-CRS. Oko kukuthi, imeko yesigulana isenokungafaneleki utyando. Kwanakwabo bantu, unyango lokuthomalalisa lunokunceda ukulawula iimpawu nokunciphisa iintlungu. Unyango lokuthomalalisa lunyango olunceda isigulana ukuba sikhululeke kangangoko kunokwenzeka, nokuba sikwinqanaba lomhlaza.

Ngaba kukho naziphi na iingxaki zonyango?

Uphando lwamva nje lubonisa ukuba zombini i-CRS kunye ne-HIPEC ziindlela zonyango ezikhuselekileyo nezisebenzayo xa izigulana zihlolwe ngononophelo kwaye zikhethwe ngokufanelekileyo. Iziphumo zilungile ngakumbi xa utyando lwenziwa kwiziko elinamava elihlala lenza olu nyango.

Nangona kunjalo, njengalo naluphi na utyando olukhulu, kukho iingxaki ezithile ezinokwenzeka. Nangona zingaqhelekanga, ezi zinokuba yingozi ebomini ukuba azinyangwa ngokukhawuleza. Ezi ziquka:

• Ukopha kakhulu
• Ukugqobhoka kwesitho somzimba
• Ukuvuza kwe-anastomotic emva kotyando
• Usulelo
• Ithumba
• I-Sepsis ( imeko embi kakhulu ebangelwa ziintsholongwane ezingena egazini)

Ugqirha wakho uza kukuchazela konke oku kwangaphambili. Into ebalulekileyo kukuba uqonde indlela iingenelo zonyango ezidlula ngayo iingozi.

Ithini i-prognosis ye-peritoneal carcinomatosis?

Ingxaki yokubikezela isifo esibi esinxulunyaniswa ne-peritoneal carcinomatosis ngoku iphucuke kakhulu ngokufika konyango lwe-CRS kunye ne-HIPEC. Nangona kungekho nyango lwale meko, olu nyango lunceda izigulane ziphile ixesha elide .

Kwabo baye batyandwa ukuze kususwe yonke imikhondo yomhlaza (CRS), ama-45% ayaphila emva kweminyaka emihlanu. Oko kukuthi, amashumi amane anesihlanu ekhulwini abo baye baphumelela kwi-CRS baphila iminyaka emihlanu. Nangona kunjalo, ukuba utyando alunakuwususa ngokupheleleyo umhlaza, izinga lokusinda leminyaka emihlanu lingaphantsi kwe-10%.

Kukho nezinye izinto ezininzi ezichaphazela indlela ocinga ngayo:

• Uhlobo lomhlaza oyintloko
• Indlela ezibonakala zingaqhelekanga ngayo iiseli zomhlaza
• Iimpawu zakho zinzima kangakanani
• Inqaku lakho le-PCI

Ugqirha wakho angakuchazela ngakumbi ngezi zinto zichaphazela imeko yakho.

Ndingazinyamekela njani? (Ukuzinyamekela)

Ukuphila nomhlaza osasazekayo, imeko efana ne-peritoneal carcinomatosis, kunokuba nzima. Iimpawu zomzimba zinokwenza kube nzima ukudlula usuku. Kwaye ukungaqiniseki malunga nendlela umzimba wakho oza kusabela ngayo kunyango kunokuba nzima ngokweemvakalelo.

Yingakho kubalulekile ukufumana lonke uncedo onokulufumana.

Oku kungabandakanya ukufumana unyango lokudambisa iimpawu. Kukwangumbono olungileyo ukufuna iingcebiso zokukunceda ujongane neemvakalelo ezinzima eziza nokuxilongwa. Kuluncedo ngakumbi ukujoyina iqela lenkxaso apho unokunxibelelana nabanye abaphila neemeko zomhlaza eziphucukileyo njengawe. Oku kunokukunceda uzive ungedwa kwaye ungafunda kumava abanye.

Buza ugqirha wakho ngezixhobo ezinokwenza kube lula ukuphila ne-peritoneal carcinomatosis.

Ndifanele ndimbone nini ugqirha?

Kuya kufuneka ubone ugqirha wakho rhoqo ukuze ubone ukuba unyango lwakho lusebenza kakuhle kangakanani na. Okwangoku, ukuba ubonakalisa iimpawu ezintsha okanye ukuba iimpawu zakho ziya zisiba mandundu, xelela ugqirha wakho ngoko nangoko.Emva koko angacebisa unyango olongezelelweyo okanye utshintsho kwisicwangciso sakho sonyango olunokukunceda.

Ndingayibuza yiphi imibuzo ugqirha wam?

Xa udibana nogqirha wakho, kungcono ukubuza imibuzo efana nale:

• Zeziphi iimvavanyo ekufuneka ndizenze?
• Luhlobo luni lonyango olundicebisayo?
• Zeziphi iziphumo ebezingalindelekanga endinokuzilindela kunyango?
• Zeziphi iziphumo endinokuzilindela emva konyango?
• Zeziphi izixhobo ezikhoyo zokundinceda ndijamelane neempawu kunye nemiphumo emibi?

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Ngaphambili, xa umntu efunyaniswa ukuba une-Peritoneal Carcinomatosis, kwakucingwa ukuba ubomi bakhe bufutshane kakhulu. Nangona kunjalo, imeko yahlukile ngoku. Ngenxa yonyango oluphambili olufumanekayo namhlanje, ixesha lokusinda kwabantu abanale meko liye landiswa kakhulu.

Nangona kunjalo, amava akho aya kuxhomekeka kwisifo sakho esithile. Ugqirha wakho angakuchazela ukuba ungumntu ofanelekileyo na kunyango olufana ne-CRS kunye ne-HIPEC. Angakudibanisa nezixhobo ukuqinisekisa ukuba ufumana inkxaso oyifunayo ukuze uhlangabezane nale meko.

Ungaze ulahle ithemba. Ukufumana ulwazi olufanelekileyo, ukufumana unyango ngexesha elifanelekileyo, nokufumana inkxaso yengqondo neyomzimba oyifunayo kubaluleke kakhulu kule mfazwe.

I- Peritoneal Carcinomatosis, I-Peritoneal Carcinomatosis, Umhlaza, I-Peritoneum, i-Ascites, i-CRS, i-HIPEC, Iimpawu zoMhlaza, Unyango loMhlaza