Ngaba uziva udiniwe rhoqo, unesiyezi, okanye unengxaki yokunyuka izinyuko? Umntu usenokuba ukubuzile, "Kutheni uphaphathekile kangaka kule mihla?" Ezi zihlala ziyimpawu ze-anemia. Kodwa namhlanje siza kuthetha ngemeko engaqhelekanga ebangela i-anemia, abantu abaninzi abangazange bayive, kodwa kufuneka siyiqaphele. Yiyo leyo iPure Red Cell Aplasia , okanye i-PRCA ngamafutshane.
Ngamafutshane, yintoni iPure Red Cell Aplasia (PRCA)?
Khawuthelekelele ukuba ngaphakathi kwamathambo ethu amakhulu, umongo wethambo, kufana nomzi-mveliso omkhulu wokwenza igazi. Lo mzi-mveliso kulapho iintlobo ezintathu zeeseli ezifunekayo emzimbeni wethu, iiseli ezibomvu zegazi, iiseli ezimhlophe zegazi, kunye neeplatelets, zenziwa khona. Umsebenzi ophambili weeseli ezibomvu zegazi kukuthatha ioksijini engena emiphungeni yethu xa siphefumla size siyisasaze kuzo zonke ezinye iiseli emzimbeni wonke.
Ngoku, kwimeko ebizwa ngokuba yiPure Red Cell Aplasia (PRCA) , umgca wemveliso yefektri eyenza iiseli ezibomvu zegazi uyeka ukusebenza ngequbuliso. Ukuveliswa kwezinye iintlobo zeeseli, ezizezi iiseli ezimhlophe zegazi kunye neeplatelets, ngesiqhelo akutshintshi kangako. Xa kuphela ukuveliswa kweeseli ezibomvu zegazi kuyeka, inani leeseli ezibomvu zegazi emzimbeni liyehla kancinci. Oku sikubiza ngokuba yi-anemia . Xa kungekho ziseli zaneleyo zokuthwala ioksijini emzimbeni wonke, iimpawu ezikhankanyiweyo ngaphambili, njengokudinwa nobuthathaka, ziqala ukubonakala.
Ziziphi iimpawu eziqhelekileyo ze-PRCA?
I-PRCA yimeko ebangela i-anemia enzima, ngoko ke iimpawu zibonakala ngakumbi kunezo zibonwa kwi-anemia eqhelekileyo.
| Uphawu | Ingcaciso elula |
|---|---|
| Ukudinwa | Uziva udiniwe kangangokuba awukwazi kugqiba usuku, ingasathethwa ke ngokwenza umsebenzi onzima. |
| Ubunzima bokuphefumla (i-Dyspnea) | Ukuziva uphelelwa ngumphefumlo ngelixa usenza imisebenzi eqhelekileyo, uhamba, okanye unyuka izinyuko. |
| Isiyezi | Ukuziva unesizungu ngenxa yokuncipha komthamo weoksijini efunekayo engqondweni. |
| Ulusu olukhanyayo | Ulusu, imilebe, kunye neenzipho zibonakala zimhlophe ngenxa yokungabikho kweeseli ezibomvu zegazi, nto leyo eyenza ulusu lube nombala opinki. |
| Intloko ebuhlungu | Intloko ebuhlungu ebangelwa kukuncipha kokunikezelwa kweoksijini engqondweni. |
| Ukuva iingxolo ezindlebeni (i-Pulsatile Tinnitus) | Ukuva isandi ezindlebeni ngokwesingqi sokubetha kwentliziyo. |
| Intlungu yesifuba (i-Angina) | Intlungu yesifuba ebangelwa kukungabikho komoya-mpilo owaneleyo kwimisipha yentliziyo. |
Kutheni le nto imeko engaqhelekanga kangaka isenzeka?
Akukho sizathu sinye se-PRCA. Kukho izinto ezininzi ezibangela oku. Ngamanye amaxesha inokwenzeka njengesiphumo esingesinye sezifo ezifihlakeleyo.
- Izifo Ezizikhusela Ngokwasemzimbeni: Ngamafutshane, oku kuxa inkqubo yokuzikhusela yomzimba wethu (inkqubo yokuzikhusela) ihlasela ngempazamo imizimba yethu. Ngamanye amaxesha olu hlaselo lunokuhlasela iiseli ezikumongo wethambo ezenza iiseli ezibomvu zegazi. Umzekelo, i-PRCA inokwenzeka kwizifo ezifana ne-`(Systemic Lupus Erythematosus - SLE)` kunye ne-`(Rheumatoid Arthritis)`.
- Umhlaza Wegazi: Kukho umngcipheko wokuba ne-PRCA kwiintlobo ezithile zomhlaza ezinxulumene negazi, ingakumbi i-Chronic Lymphocytic Leukemia (CLL) kunye ne-Large Granular Lymphocytic Leukemia (LGL).
- IiTumors Ezinomhlaza: I-Thymoma sisimila esinomhlaza esikhula kwi-thymus gland esifubeni. Oku kungaba yimbangela enkulu ye-PRCA.
- Iintsholongwane: I-Parvovirus B19Intsholongwane ebangela i-PRCA yeyona nto ibangela oku. Le ntsholongwane ihlasela ngokuthe ngqo iiseli ze-stem kwi-bone mongo ezibangela ukwenza iiseli ezibomvu zegazi. Ingabangelwa yi-HIV, i-Epstein-Barr virus, kunye neentsholongwane ze-hepatitis.
- Usulelo lweeBhaktheriya: Usulelo olubi lweebhaktheriya, olufana nesifo sephepha, nalo alunakubangela i-PRCA.
- Amayeza athile: I-PRCA inokwenzeka njengesiphumo esingesihle samayeza athile.
- Ukukhulelwa: Kunqabile kakhulu, abanye abafazi banokuba ne-PRCA yexeshana ngexesha lokukhulelwa. Nangona kunjalo, imeko idla ngokuphela ngokuzenzekelayo emva kokubeleka.
Ugqirha uxilonga njani esi sifo?
Ukuba uneempawu ezichazwe apha ngasentla, ugqirha uza kuqala akuhlole aze emva koko akucebise ukuba wenze iimvavanyo ezininzi ukuqinisekisa ukuba unesifo.
- Inani elipheleleyo legazi (CBC): Oku kulinganisa inani leeseli ezibomvu zegazi, iiseli ezimhlophe zegazi, kunye neeplatelets egazini lakho. Kwi-PRCA, inani leeseli ezibomvu zegazi liphantsi kakhulu.
- Inani leeReticulocyte: Oku kulinganisa inani leeseli ezibomvu zegazi ezingavuthwanga ezisandula ukwakheka kumongo wethambo kwaye zongezwa egazini. Kwi-PRCA, eli nani liphantsi kakhulu.
- I-Peripheral Blood Smear: Ithontsi legazi liyathathwa lize lihlolwe phantsi kwemakroskopu ukujonga imo kunye nohlobo lweeseli ezibomvu zegazi.
- Uvavanyo lweParvovirus B19: Olu vavanyo lwenziwa ukuba kukho ukurhanelwa kokuba kukho usulelo lwentsholongwane.
- I-CT Scan: Olu vavanyo lungenziwa ukuba kukho isityholo sokuba kukho ithumba elifana ne-"Thymoma" esifubeni.
- Ukufutha/Ukuxilongwa kweBone Marrow: Olu lolona vavanyo lubalulekileyo lokuqinisekisa isifo. Inaliti encinci isetyenziselwa ukususa isampuli yomongo wethambo kwindawo efana nethambo lesinqe phantsi kwe-anesthesia. Kwi-PRCA, oku kunokuqinisekisa ukuba umongo wethambo uphelelwe ngokupheleleyo ziiseli ezibomvu zegazi.
Iphathwa njani i-PRCA?
I-PRCA inyangwa ngokuchonga unobangela wesifo kunye nokulungisa loo nobangela.
Eyona nto ibalulekileyo kukuba olu nyango lufanele lwenziwe phantsi kweliso likagqirha wakho. Ukusela amayeza ngokwakho kunokuba nemiphumo emibi kakhulu.
Kukho iindlela ezininzi zonyango:
- Izinto ezithintela amajoni omzimba: Ukuba unobangela wesifo yingxaki ekusebenzeni kwenkqubo yomzimba yokuzikhusela, amayeza anjenge `(Corticosteroids)` (umz. iPrednisone) kunye `(iCyclosporine)` ayanikwa ukuze ayilawule.
- Utofelo-gazi:Ukuba inani legazi liphantsi kakhulu kwaye iimpawu zinzima, utofelo-gazi lunikwa njengesiqabu esikhawulezileyo. Kodwa esi sisisombululo sexeshana. Ekubeni utofelo-gazi oluqhubekayo lunokubangela ukuba isinyithi siqokeleleke emzimbeni, unyango olwahlukileyo (iChelation Therapy) luyafuneka ukuze kususwe isinyithi esigqithisileyo.
- Utyando: Ukuba unobangela wesifo yi-thymus gland tumor (Thymoma), kwenziwa utyando lokususa i-gland (Thymectomy).
- Ukufakelwa kweeSeli zeStem: Kwezinye iimeko zemfuza, iiseli zestem ezithathwe kumntu ophilileyo ziyatyalwa ukuze kuzanywe inkqubo entsha yomongo wethambo ophilileyo.
- Unyango lwe-Immunoglobulin: Ukuba i-PRCA ibangelwa lusulelo lweParvovirus B19, olu nyango lulawula intsholongwane.
Masifunde nangemiphumo emibi yonyango.
Njengazo zonke iindlela zonyango, unyango lwe-PRCA lunokubangela ezinye iziphumo ebezingalindelekanga. Kodwa ugqirha wakho uza kukuchazela konke oku kwangaphambili.
Iziphumo ebezingalindelekanga zamayeza okunciphisa umzimba
- Ukwakheka kwamaqhakuva
- Umngcipheko wokuba nesifo seswekile
- Igazi elonyukayo
- I-Osteoporosis
- Ukutyeba kwakho
- Ukuphazamiseka kwesisu kunye nesicaphucaphu
Iziphumo ebezingalindelekanga zotofelo-gazi
- Umkhuhlane kunye nee-aleji (ukurhawuzelelwa)
- Ingozi yokosuleleka
- Ukugqithisa isinyithi
Ezi ziphumo ebezingalindelekanga azenzeki kuye wonke umntu, kwaye ugqirha wakho uza kukunceda uzilawule. Ngoko ke akukho mfuneko yokukhathazeka.
Kunjani ukuhlala ne-PRCA kwaye ndizinyamekela njani?
I-PRCA ngamanye amaxesha inokuba yimeko engapheliyo. Esi sifo sinokuphela ngokupheleleyo emva konyango okanye singaphinda sibuye. Ke ngoko, kukho izinto ezininzi ekufuneka uziqwalasele xa uphila nale meko.
- Bona ugqirha wakho rhoqo: Nokuba iimpawu zakho ziyanyamalala emva konyango, qiniseka ukuba uya kuhlolwa ngamaxesha athile achazwe ngugqirha wakho. Oku kuya kukunceda ubone umngcipheko wokuba isifo sibuye kwangethuba.
- Iidosi zokugcina: Abanye abantu banokufuna ukuqhubeka bethatha amayeza ngedosi ephantsi ukuthintela ukuba isifo singabuyi.
- Indlela yokuphila esempilweni:
- Ukutya okulungileyo: Buza ugqirha wakho malunga nokutya okune-iron eninzi kunye nokutya okunesondlo.
- Sela amanzi aneleyo: Khusela umzimba ekuphelelweni ngamanzi emzimbeni.
- Ukuzilolonga: Zilolonge ngokukhuselekileyo okufanelekileyo kuwe, njengoko ugqirha wakho ekucebisile.
- Zikhusele kwiintsholongwane:Hlamba izandla zakho rhoqo. Lumka kwiindawo ezinabantu abaninzi. Thetha nogqirha wakho malunga naluphi na ugonyo olufunekayo.
- Nika ingqalelo kwiimpawu zakho: Ukuba ubona naluphi na utshintsho emzimbeni wakho okanye naziphi na iimpawu ezintsha, yazisa ugqirha wakho.
Umyalezo Wokuya Ekhaya
- I-Pure Red Cell Aplasia (PRCA) yimeko engaqhelekanga kodwa enzulu ebangela ukuba umongo wethambo uyeke ukuvelisa iiseli ezibomvu zegazi.
- Ingxaki ephambili ebangelwa koku yi-anemia enzima. Iimpawu eziphambili kukudinwa kakhulu, ukuphaphatheka, kunye nobunzima bokuphefumla.
- Zininzi izizathu zoku, apho iingxaki zenkqubo yomzimba yokuzikhusela, umhlaza, kunye nosulelo lweentsholongwane zezona ziphambili.
- Uvavanyo lwegazi kunye nokuhlolwa komongo wethambo kubalulekile ukuze kufunyanwe isifo ngokuchanekileyo.
- Kukho unyango olusebenzayo kakhulu olufumanekayo ngokuxhomekeke kwisizathu sesifo. Nangona kunjalo, njengoko isifo sinokuphinda sibuye, kubaluleke kakhulu ukulandela imiyalelo kagqirha wakho.
- Ukuba wena okanye umntu omaziyo unezi mpawu, musa ukoyika kwaye funa ingcebiso kagqirha ngokukhawuleza.
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