Ingaba oku kuyingozi nakwizintso zakho? (Isifo seRenal Papillary Necrosis) Masifunde ngako!

Uyazi ukuba zisebenza kangakanani izintso ezimbini ezincinci emzimbeni wethu? Enyanisweni, izintso zezona zitho ziphambili ezihluza imveliso engcolileyo kwaye zicoce igazi emzimbeni wethu. Nangona kunjalo, ngamanye amaxesha ezi zintso zinokukhula nezifo esingazilindelanga. Namhlanje siza kuthetha ngemeko enzima kancinci, kodwa ukuba uyazi, inokukunceda uyilawule kwaye uyithintele.

Zisebenza njani izintso? Yintoni iRenal Papillary Necrosis?

Ngamafutshane, izintso zethu zifana nezihluzo ezimbini ezinkulu emzimbeni wethu. Umsebenzi wazo ophambili kukucoca imveliso engafunekiyo egazini kwaye uyikhuphe njengomchamo. Ukuze wenze oku, igazi lingena kwizintso kwaye lidlule kwiindlela ezininzi ezincinci. Le mveliso yenkunkuma iqokelelwa kwinxalenye engaphandle yezintso ize ifike embindini wezintso, okuyi -kidney medulla . Nazi iindawo ezimile njenge-funnel. Incam yezi funnel, ezibizwa ngokuba yi-renal papilla, iqokelela umchamo. Ukusuka apho, umchamo udlula kwi-ureters uye kwisinyi uze uphume. Yindlela ezisebenza ngayo izintso zethu.

I-renal papillary necrosis esithetha ngayo ngoku kukufa kweeseli kunye nezicubu eziphakathi kwinxalenye yentso (`Medulla`) kunye ne-renal papilla (`Renal Papilla`) endikhankanyileyo ngaphambili. Cinga nje, xa ezo ndawo zingasebenzi kakuhle, umsebenzi owenziwa zizintso awusebenzi kakuhle, akunjalo? Ngenxa yoku, izintso ziba buthathaka kancinci kancinci, kwaye ekugqibeleni zinokukhokelela ekungasebenzini kwezintso .

Ngubani osengozini enkulu yokuba nale meko?

Le meko (iRenal Papillary Necrosis) ixhaphake kakhulu kubantu abaneminyaka engaphezu kwama-60 ubudala. Oogqirha bakwathi abafazi banokuba nayo kakhulu kunamadoda.

Zithini izizathu ze-Renal Papillary Necrosis?

Kukho izizathu ezininzi eziphambili ezibangela ukuba esi sifo sivele. Makhe sijonge ukuba zeziphi.

• Isifo seswekile : Esi sesona sizathu sibalulekileyo nesixhaphakileyo. Abantu abanesifo seswekile esingalawulwa kakuhle basengozini enkulu yokonakala kwezintso. Amanqanaba aphezulu eswekile egazini ixesha elide awonakalisa imithambo yegazi ebuthathaka kwizintso.
• Ukusetyenziswa kakhulu kwe-painkillers (NSAIDs) : Ukuba usebenzisa rhoqo i-painkillers (iziyobisi ezichasene nokuvuvukala ezingezizo ii-steroidal, okanye ii-NSAIDs) ezifana ne-aspirin, i-ibuprofen, okanye i-naproxen ixesha elide ngaphandle kokubonisana nogqirha, kufuneka uqaphele kakhulu. Ukusela kakhulu kwezi zinto kunokubangela ukuba imithambo yegazi kwizintso inciphe kwaye yonakalise i-renal papillae.
• Isifo seSickle Cell: Esi sisifo esibangelwa lufuzo. Kwesi sifo, imilo yeeseli ezibomvu zegazi iyatshintsha kwaye zinokunamathela kwimithambo yegazi. Oku kunokubangela ukuba igazi eliya kwizintso lingasebenzi kakuhle (iRenal Papillary Necrosis).

Ukongeza kwezi zizathu ziphambili, ezinye iimeko ezininzi zinokubangela i-Renal Papillary Necrosis:

• Isifo Sesibindi Esingapheliyo
• I-Pyelonephritis, usulelo lwebhaktheriya lwezintso (olunokonakalisa i-renal papillae)
• Isifo sephepha sezintso, isifo esichaphazela izintso ngaphandle kwemiphunga
• I-Renal Vein Thrombosis (igazi eliqhekekayo emthanjeni elithwala igazi elisuka kwizintso)
• Ukuvaleka komchamo (umzekelo, ngenxa yamatye omchamo)
• I-Vasculitis, ukudumba kwemithambo yegazi

Into ebalulekileyo kukuba ayinguye wonke umntu onesinye okanye ngaphezulu kwezi zizathu oza kuba neRenal Papillary Necrosis, kodwa umngcipheko uphezulu.

Ingaba oku kuchaphazela zombini izintso?

Ewe, kuxelwe ukuba kubantu abasixhenxe kwabalishumi , le meko (iRenal Papillary Necrosis) ichaphazela zombini izintso .

Zithini iimpawu ze (Renal Papillary Necrosis)?

Kwinqanaba lokuqala lesi sifo, kusenokungabikho zimpawu . Yiyo loo nto kunzima ukuyibona nokuyinyanga kwangethuba. Khawuthelekelele, awunazo iingxaki, kodwa izintso zakho zisenokonakala ngaphakathi. Nangona kunjalo, kusenokwenzeka ukuba oku kufunyenwe ngengozi xa kuvavanywa esinye isifo.

Nangona kunjalo, xa imeko (i-Renal Papillary Necrosis) iba mandundu, iimpawu ezifana nezi zinokuvela:

• Ukuchama okubuhlungu (iDysuria)
• Umkhuhlane kunye nokubanda (ingakumbi ukuba kuhamba nosulelo)
• Igazi kumchamo (`Hematuria`) - Ubungakanani begazi bunokubonakala emehlweni (umchamo unokuba bomvu okanye ube mdaka), okanye unokuba mncinci kangangokuba unokubonwa kuphela nge-microscope.
• Ukusoloko ufuna ukuchama ebusuku (`Nocturia`)
• Ukwanda okungaqhelekanga kwenani leeseli ezimhlophe zegazi kumchamo (`Pyuria`) - oku kuthetha ukuba umchamo ungabonakala ngathi yi-pus, kwaye umchamo ungabonakala unamafu.
• Intlungu ebuhlungu kumacala omabini omqolo, phakathi kweembambo kunye namathambo esinqeni (apho kukho izintso). Le ntlungu inokuvela ngequbuliso okanye ikhule kancinci kancinci.
• Usulelo oluqhelekileyo lwendlela yomchamo.

Ifunyanwa njani i-Renal Papillary Necrosis?

Oogqirha baza kwenza iimvavanyo ezininzi ukuze baxilonge esi sifo (iRenal Papillary Necrosis). Emva kokumamela iimpawu zakho kunye nembali yezonyango, banokuyalela iimvavanyo ezifana nezi:

• I-Urography: Oku kuquka ukuthatha i-X-ray, i-CT scan, okanye i-MRI yezintso zakho. Ngaphambi kovavanyo, uza kunikwa idayi ekhethekileyo (idayi) ngomthambo. Oku kunceda ukubona ngokucacileyo iindawo ezinomonakalo kwizintso kunye notshintsho kwi-papillae.
• I-Ureteroscopy : Oku kuquka ukufaka ityhubhu encinci neguquguqukayo (enekhamera ekupheleni) kwi-urethra ukuze ijonge ngqo ngaphakathi kwesinyi, ii-ureters, kunye nezintso. Oku kuvumela imeko ye-papillae ukuba ibonakale ngokucacileyo.
• I-Kidney Biopsy : Kolu vavanyo, kuthathwa iqhekeza elincinci lesicubu sezintso kusetyenziswa inaliti ekhethekileyo kwaye lihlolwe ngemakroskopu. Oku kunokunceda ekuqinisekiseni ukuba iiseli zifile okanye isicubu sonakele.

Uvavanyo lwegazi nomchamo

Ukongeza, uvavanyo lwegazi nomchamo ukujonga ukusebenza kwezintso nako kubaluleke kakhulu:

• Uvavanyo lwe-urea nitrogen egazini (BUN) : Olu vavanyo lulinganisa ubungakanani be-urea nitrogen egazini. Le yimveliso elahlekileyo. Eli nqanaba liyanda egazini xa izintso zingasebenzi kakuhle.
• Uvavanyo lweCreatinine : I-Creatinine yenye imveliso yenkunkuma eveliswa ngexesha lokusebenza kwemisipha okuqhelekileyo. Idla ngokukhutshwa zizintso. Ukuba umgangatho wayo uphezulu egazini, oko kubonisa ukuba izintso azisebenzi kakuhle.
• Iqondo Lokucoca I-Glomerular Eliqikelelweyo (i-eGFR) : Oku kubalwa ngokuthathela ingqalelo izinto ezifana nenqanaba le-creatinine egazini lakho, ubudala, isini, kunye nobukhulu bomzimba. Ixabiso le-eGFR likuxelela ukuba ingakanani igazi elihluzwa zizintso zakho ngomzuzu. Okukhona eli xabiso liphantsi, kokukhona izintso zakho zingasebenzi kakuhle.
• Uhlalutyo lomchamo : Oku kuquka ukuthatha isampuli yomchamo uze uwuhlole ngamehlo (umbala, ukucaca), ngemicroscope (kwiiseli zegazi, iiseli zobomvu, iibhaktheriya, ukungcola kwe-papillary), kunye nangekhemikhali (kwiiproteni, iswekile). Ngamanye amaxesha, iziqwenga ze-renal papillae zinokubonwa phantsi kwemicroscope.
• Umlinganiselo weproteni/creatinine yomchamo : Oku kulinganisa ukuba ingakanani iproteni ekwimchamo. Izintso eziphilileyo zikhupha iproteni encinci kakhulu. Amanqanaba aphezulu eproteni kumchamo luphawu lomonakalo wezintso.

Ziziphi iingxaki ezinokubakho ze (Renal Papillary Necrosis)?

Ukuba le meko (iRenal Papillary Necrosis) ayinyangwa kakuhle, le meko inokuba mandundu kwaye ikhokelele kwiingxaki ezinkulu.

• Isifo Sezintso Esingapheliyo (CKD) : Ngenxa yomonakalo oqhubekayo kwizintso, ukusebenza kwazo kuyehla kancinci kancinci, nto leyo ekhokelela kwisifo sezintso esingapheliyo.
• Ukusilela Kwezintso: Ukuba imeko iba mandundu, izintso zisenokungasebenzi kakuhle ngokupheleleyo, oko kuthetha ukuba zisenokuba zingasebenzi kakuhle kwizintso.
• Ukuze uphile, ungadinga i-dialysis (ukucoca igazi lakho ngomatshini) okanye ukufakelwa izintso .
• Kukwafunyaniswe ukuba le meko inyusa umngcipheko wokufumana uhlobo lomhlaza olubizwa ngokuba yi -transitional cell cancer, olukhula kwizintso okanye kwi-ureter.
• Kukwakho nomngcipheko wosulelo oluqatha (i-sepsis).

Inyangwa njani i-Renal Papillary Necrosis?

Akukho nyango lukhethekileyo lwe-Renal Papillary Necrosis. Unyango oluphambili kukunyanga unobangela oyintloko wale meko . Umzekelo:

• Ukuba kungenxa yesifo seswekile, kubalulekile ukulawula isifo seswekile kakuhle.
• Ukuba kungenxa yokusebenzisa ii-NSAID, yeka ukusebenzisa loo mayeza.
• Ukuba kungenxa yosulelo, yinike amayeza okubulala iintsholongwane.
• Ukuba kukho ukuvaleka kwendlela yomchamo, kufuneka kususwe.

Injongo ephambili kukunciphisa umonakalo ongakumbi kwizintso nokugcina ukusebenza kwezintso kangangoko kunokwenzeka.

Impumelelo yonyango ixhomekeke kubungakanani bomonakalo wezintso kunye nesizathu sesifo. Kwezinye iimeko ezinzima, isifo sinokuqhubeka siba mandundu nangona unyango lusenziwa. Nangona kunjalo, kwiimeko ezingezizo ezinzima kangako, kwaye ukuba unobangela unyangwa ngokukhawuleza, ukusebenza kwezintso kunokuzinza okanye kuphucuke kancinci.

Ndingazikhusela kwi-Renal Papillary Necrosis?

Ewe, zikho izinto esinokuzenza ukuze sizikhusele kule meko, ubukhulu becala.

• Eyona nto ibalulekileyo kukugcina impilo yakho iyonke . Ukutya ukutya okunesondlo, ukusela amanzi aneleyo, kunye nokuzilolonga rhoqo kubalulekile.
• Ukuba usebenzisa amayeza okudambisa iintlungu (ii-NSAIDs) athengiswa ngaphandle kwemvume kagqirha, zisebenzise kuphela njengoko kuyalelwe kwiphakheji okanye njengoko kuyalelwe ngugqirha. Musa ukuzisebenzisa rhoqo okanye ixesha elide kunokuba kuyimfuneko. Musa ukuzisebenzisa rhoqo xa kukho iintlungu ezincinci okanye xa kukho intloko ebuhlungu.
• Ukuba unesifo seswekile (iDiabetes Mellitus), isifo se-sickle cell (iSickle Cell Disease), okanye ezinye izifo ezinokubangela isifo sezintso (iRenal Papillary Necrosis), landela imiyalelo kagqirha wakho ngokuchanekileyo. Yiya kwiikliniki ngexesha. Sela amayeza amiselweyo. Landela ukutya okufanelekileyo.
• Kubaluleke kakhulu ukuba wenze uvavanyo lwelabhoratri ukujonga ukusebenza kwezintso rhoqo njengoko kuyalelwe ngugqirha wakho, kwaye uchonge naluphi na utshintsho kwangethuba.

Lingakanani izinga lokuchacha komntu onesi sifo?

Ingqikelelo yakho ixhomekeke kwisizathu sesifo, ubungakanani bomonakalo wezintso, impilo yakho iyonke, kunye nokuba uqala ngokukhawuleza kangakanani unyango.

• Kubantu abanesifo seswekile, iziphumo zisenokungabi ntle kangako , njengoko isifo seswekile sisifo esihlala ixesha elide kwaye asisoloko silawulwa kakuhle. Ukuba unesifo seswekile, ukusilawula kakuhle kangangoko kunokwenzeka kuya kunceda kakhulu ekuthinteleni ukonakala kwezintso.
• Kwiimeko ezinzima kakhulu (iRenal Papillary Necrosis), inokukhokelela kwi- dialysis kunye nokufakelwa kwezintso . Ukuba kukho usulelo, lunokuba yingozi ebomini. Kukho ithuba lokufa ngenxa yokungasebenzi kakuhle kwezintso.
• Kwisifo se-sickle cell, i-renal papillary necrosis yenye nje yeengxaki ezininzi ezinokwenzeka kwizintso. Xa zonke ezi ngxaki zidityanisiwe, ixesha lokuphila kwesigulana linokuncipha kakhulu.

Ndifanele ndimbone nini ugqirha?

Ukuba unenye okanye ngaphezulu kwezi mpawu, musa ukuchitha ixesha kwaye ngokuqinisekileyo bonana nogqirha :

• Ukuba unegazi kumchamo wakho (umchamo ujika ube bomvu, upinki, okanye ube mdaka).
• Ukuba unomkhuhlane okanye ubanda (ingakumbi xa kukho ezinye iimpawu).
• Ukuba unentlungu okanye utsha xa uchama.
• Ukuba unentlungu entsha okanye eyandayo kumacala omabini omqolo wakho, kwindawo ephakathi kwamathambo esinqe kunye neembambo (indawo yezintso).
• Ukuba ufumana usulelo oluhlala lukho kwindlela yomchamo.
• Ukuba uncipha umchamo okanye ukudumba emilenzeni nasemaqatheni (ezi zisenokuba ziimpawu zokungasebenzi kakuhle kwezintso).

Khumbula, ezi mpawu zinokubangelwa nazezinye izifo. Nangona kunjalo, kubalulekile ukuya kugqirha ukuze kufunyaniswe unobangela ochanekileyo.

Okokugqibela, yintoni ekufuneka uyikhumbule (Umyalezo Wokuya Ekhaya)

Izintso zethu ziyinxalenye ebalulekileyo yomzimba wethu, zenza umsebenzi othuleyo nobalulekileyo. Zihluza imveliso engcolileyo kwaye zigcina ulungelelwano lwamanzi netyuwa emzimbeni. Isifo seswekile esingalawulwayo, ukusetyenziswa kakhulu kwee-NSAIDs, kunye nezinye iimeko ezahlukeneyo zonyango zingonakalisa izintso, nto leyo ekhokelela kwiimeko ezinzulu ezifana ne-Renal Papillary Necrosis.

Eyona nto imbi ngesi sifo kukuba usenokungabi nazimpawu kwisigaba sokuqala. Ngoko ke, ukuba unesifo seswekile, usebenzisa rhoqo ii-NSAID, okanye unezinye izinto ezinokubangela isifo sezintso, thetha nogqirha wakho malunga neendlela zokukhusela izintso zakho. Ngokufumana uhlolo rhoqo kunye nendlela yokuphila enempilo, unokugcina izintso zakho ziphilile. Ukwazi kwangethuba kunye nesenzo kusoloko kuyinto engcono ukuyenza.

Izintso , i-renal papillary necrosis, isifo sezintso, isifo seswekile, ii-NSAIDs, ukungasebenzi kakuhle kwezintso, umchamo