Ngaba uyayazi iSheehan Syndrome, enokwenzeka emva kokubeleka?

Uyakhumbula indlela esasithetha ngayo ngamanye amaxesha ngokuba oomama bafumana iimpawu ezingaqhelekanga emva kokubeleka? Mhlawumbi abavelisi ubisi olwaneleyo lomntwana wabo, ukuya kwabo exesheni ngequbuliso kuyaphela, okanye bazive bediniwe kakhulu imini yonke. Ezi azizozinto nje ezingaqhelekanga, ngamanye amaxesha zinokuba ngumphumo weengxaki ngexesha lokubeleka. Namhlanje siza kuthetha ngemeko engaqhelekanga kodwa ebaluleke kakhulu enxulumene nokuzala ekufuneka wonke umntu ayiqaphele.

Yintoni iSheehan Syndrome?

Ngamafutshane, iSheehan Syndrome sisifo esingaqhelekanga esichaphazela i-pituitary gland yakho. Siyenzeka xa kukho ukopha okugqithisileyo ngexesha lokubeleka, oko kuthetha ukuba igazi elininzi lilahleka emzimbeni. Cinga ngayo, i-pituitary gland yakho yi-gland encinci kodwa ebaluleke kakhulu ezantsi kwengqondo. Siyibiza ngokuba yi-"master gland" kuba ivelisa iihomoni ezilawula iinkqubo ezininzi ezibalulekileyo emzimbeni, kwaye ikwaxelela amanye ama-gland ukuba avelise iihomoni. Ke, xa kukho ukopha okugqithisileyo ngexesha lokubeleka, le pituitary gland ayifumani ubuninzi beoksijini eyidingayo. Njengokuba umthi ufa ngaphandle kwamanzi, xa ungenawo umoya-mpilo, ezinye izicubu kwi-pituitary gland ziyafa. Le pituitary gland iba nkulu kancinci ngexesha lokukhulelwa, ngoko ke kunokwenzeka ukuba yonakale. Xa i-pituitary gland yonakele ngale ndlela, inokuchaphazela iinkqubo ezahlukeneyo emzimbeni, ezifana nengqondo, inkqubo yokuzala, izihlunu, ulusu, amandla, kwanengqondo. Le Sheehan Syndrome ikwabizwa ngokuba yi-'postpartum hypopituitarism' okanye 'postpartum pituitary necrosis'.

Kwenzeka ntoni emzimbeni one-Sheehan syndrome?

Xa i-pituitary gland yonakele, ilahlekelwa ngamandla ayo okuvelisa iihomoni ezininzi ezibalulekileyo ezifunekayo emzimbeni. Nazi ezi zinto:

• I-Adrenocorticotrophic hormone (ACTH): Oku kukhuthaza ukuveliswa kwe- cortisol, eyona hormone iphambili yoxinzelelo emzimbeni. I-Cortisol yi-hormone elawula uxinzelelo lwegazi, amanqanaba eswekile egazini, kwaye inceda umzimba ukuba ukwazi ukumelana noxinzelelo.
• Ihomoni evuselela i-thyroid (TSH): Le hormone ivuselela i-thyroid gland . I-thyroid ilawula imetabolism, amandla, kunye nenkqubo yemithambo-luvo.
• I-Growth hormone (GH): Inceda ukugcina uxinano lwamathambo, ubunzima bemisipha, kunye nokusasazwa kwamafutha.
• I-Follicle-stimulating hormone (FSH): Ivuselela ukuveliswa kwe-estrogen kwii-ovari, kwaye ibangela ukuba iqanda livuthwe inyanga nenyanga.
• I-hormone ye-Luteinizing (LH):Inceda ekukhupheni iqanda, oku kuthetha ukukhululwa kweqanda kwii-ovari.
• I-Prolactin (PRL): Ivuselela imveliso yobisi ngexesha lokukhulelwa kwaye ivumela umntwana ukuba ancancise.

Ngoko ke mhlawumbi ungaqonda ukuba ukuba kukho naliphi na kwezi hormone elingekhoyo, umsebenzi ofanelekileyo emzimbeni awuyi kusebenza kakuhle.

Ixhaphake kangakanani le meko?

Ngonyango lwanamhlanje, iSheehan Syndrome yimeko engaqhelekanga kakhulu . Iyenzeka malunga ne-5 kwi-100,000 yokuzalwa. Nangona kunjalo, isenokuba yinto eqhelekileyo kwiindawo apho unyango olungxamisekileyo lungekho khona ukuthintela ukopha kakhulu ngexesha lokubeleka.

Zithini iimpawu zoku?

Iimpawu zeSheehan syndrome ngamanye amaxesha zinokubonakala kwangoko , oko kukuthi, emva nje kokuba umntwana ezelwe. Nangona kunjalo, ngamanye amaxesha ezi mpawu zinokubonakala kancinci kancinci, kwiinyanga okanye kwiminyaka . Iimpawu eziphambili ezinokubonakala zezi:

• Ubunzima bokuncancisa okanye ukungafumani ubisi emva kokuba umntwana ezelwe.
• Ukuyeka ngokupheleleyo ukuya exesheni ngenyanga ( i-amenorrhea ) okanye ukungaqheleki.
• Iindonga zesini ziyabhitya kwaye zome ( i-vaginal atrophy ), nto leyo enokwenza ukuba isondo sibe buhlungu.
• Ukushwabana kwamabele kunye nokulahlekelwa buboya emakhwapheni nakwiindawo zangasese.
• Ukudinwa kakhulu , amandla aphantsi, kunye nobunzima bokugxila.
• Ukuncipha komnqweno wesondo.
• Uxinzelelo lwegazi oluphantsi.
• Ulusu olomileyo.

Okubalulekileyo, ngamanye amaxesha usenokungabi nazimpawu zinkulu uze ngequbuliso ufumane uxinzelelo olukhulu ebomini bakho - umzekelo, utyando, usulelo olukhulu, okanye ingozi - kwaye umzimba wakho usenokungabi na-cortisol eyaneleyo yokumelana nalo, nto leyo ekhokelela kwiimpawu. Oku kubizwa ngokuba yi-adrenal crisis . Le yimeko esongela ubomi efuna unyango olukhawulezileyo.

Kutheni iSheehan syndrome isenzeka?

Isizathu esiphambili soku kukopha kakhulu ngexesha lokubeleka . Njengoko benditshilo ngaphambili, i-pituitary gland iyanda ngexesha lokukhulelwa, ngamanye amaxesha iphindwe kabini ngobukhulu. Oku kuyenza ibe sesichengeni sokuphelelwa yioksijini, ingakumbi ukuba kukho ukopha okuninzi okanye ukwehla ngequbuliso koxinzelelo lwegazi. Xa kukho ukunqongophala kweoksijini, iiseli kwi-pituitary gland ziyachaphazeleka. Ngenxa yoko, i-pituitary gland ayikwazi ukuvelisa iihomoni ezaneleyo ukulawula imisebenzi eyahlukeneyo emzimbeni. Oku kusilela kweehomoni kunokubangela ukuba inkqubo yokuzala kunye nenkqubo yemithambo-luvo isebenze kakubi okanye ime ngokupheleleyo.

Ingaba le yinto evela kwizizukulwana ngezizukulwana?

Hayi. I-Sheehan syndrome ayisiyonto oyizuza njengelifa kubazali bakho.

Kungakanani ukulahleka kwegazi okufunekayo ukuze le meko ibe sesichengeni?

Ngokwesiqhelo, umngcipheko wokuba neSheehan's syndrome uyanda kuphela xa ulahlekelwa ligazi elisongela ubomi, ukwehla okukhulu koxinzelelo lwegazi, kunye nomothuko. Nangona kunjalo, ngenxa yokuba iqela lakho lezonyango likulungele ezi meko zingxamisekileyo, lo mngcipheko ngoku uphantsi kakhulu.

Zithini izinto ezibangela umngcipheko?

Ngoku siyazi ukuba i-Sheehan syndrome yenzeka kuphela xa kukho ukopha okugqithisileyo ngexesha lokubeleka kwaye uxinzelelo lwegazi luyehla kakhulu. Ngoko ke, iimeko ezandisa umngcipheko wokopha okugqithisileyo ngexesha lokubeleka nazo zandisa umngcipheko we-Sheehan syndrome. Ezi meko ziquka:

• Ukuzala abantwana abangaphezu komnye (njengamawele, amawele amathathu).
• Ukuzala umntwana omkhulu kunesiqhelo.
• Ukuqhawuka kwe-placenta .
• I-placenta previa (i-placenta ephantsi ).
• Uxinzelelo lwegazi oluphezulu ngexesha lokukhulelwa ( i-preeclampsia ).
• Ukuhanjiswa kwezixhobo (umz. i-forceps okanye i-vacuum extraction ).

Ziziphi iingxaki zesifo seSheehan?

Ukuba iSheehan syndrome ibangela ingxaki ye-adrenal kamva ebomini, inokuba yingozi ebomini. Ukongeza, ezinye iingxaki zale meko zingabandakanya:

• Uxinzelelo lwegazi oluphantsi.
• Ukulahlekelwa bubunzima bomzimba okanye ubunzima bemisipha.
• Ukuya exesheni okungacwangciswanga okanye ubunzima bokuphinda ukhulelwe.

Kodwa ungakhathazeki, ugqirha wakho unokukunceda ukulawula okanye ukuthintela ezi ngxaki ngonyango olufanelekileyo.

Uyibona njani le nto?

Ukuba uneempawu zesifo sikaSheehan, ugqirha wakho angasebenzisa oku kulandelayo ukuze afumanise imeko:

• Imbali yezonyango: Ugqirha wakho uza kukubuza ngazo naziphi na iingxaki oye wazifumana ngexesha lokukhulelwa kwakho. Kuya kufuneka uthethe ngazo naziphi na iimpawu oye wazifumana emva kokubeleka (umzekelo, ubunzima bokuncancisa, okanye ukungayi exesheni). Cacisa ngeempawu zakho zangoku, ukuba zikho ixesha elingakanani, kunye nento oyenzayo ukuze zibe ngcono okanye zibe mbi ngakumbi.
• Uvavanyo lwegazi: Kuthathwa isampulu yegazi lakho kwaye kujongwa amanqanaba eehomoni ezinxulumene nomsebenzi we-pituitary gland.
• Uvavanyo lwemifanekiso: Iskeni ye-MRI (Magnetic Resonance Imaging) inokususa ezinye izizathu zeempawu zakho (umzekelo, ithumba le-pituitary). Ukuba iziphumo ze-MRI azicacanga, iskeni ye-CT (i-Computed Tomography scan) nayo inokwenziwa.

Zeziphi iimvavanyo zegazi ezisetyenziselwa ukuxilonga?

Ugqirha unokuvavanya amanqanaba akho ehomoni ngokuthe ngqo, okanye banokujonga nendlela i-pituitary gland yakho esabela ngayo kwisikhuthazo esithile.

• Uvavanyo lweNqanaba leeHomoni: Amanqanaba eeHomoni afana ne-ACTH, i-FSH, i-LH, i-TSH, i-T4, i-estradiol (uhlobo lwe-estrogen), i-IGF-1, kunye ne-cortisol anokuhlolwa.
• Uvavanyo lokukhuthaza: Ugqirha wakho unokukunika amayeza okanye inaliti yokuvuselela iihomoni ezithile eziveliswa yi-pituitary gland kwaye ahlole indlela i-pituitary gland esabela ngayo kuyo.

Iphathwa njani?

Ukuze unyange le meko, kuya kufuneka uthathe iihomoni ubomi bakho bonke . Oku kuthetha ukuba umzimba wakho uza kukunika iihomoni ezingasazivelisiyo. Oku kukwabizwa ngokuba yi-hormone replacement therapy . Iintlobo zeehomoni ozifunayo, ukuba zingakanani, kunye nendlela ozithatha ngayo ziya kwahluka ngokuxhomekeke kwisifo sakho kunye neempawu. Ezi homoni zinokubandakanya:

• Iihomoni zesini: I-estrogen kunye ne-progesterone zinokusetyenziswa ukulawula ixesha lakho lokuya exesheni kwaye zincede kwiimpawu zokuya exesheni ngaphambi kwexesha. Iihomoni ezifana ne-LH kunye ne-FSH zinceda ekukhutshweni kweqanda, nto leyo enokukunceda ukuba uphinde ukhulelwe.
• IiCorticosteroids: Ungathatha i-hydrocortisone okanye i-prednisone ukunyanga ukungabikho kwe-ACTH. Umthamo wakho wezi hormones unokufuna ukulungiswa ukuba uphantsi koxinzelelo olukhulu (njengotyando) kuba umzimba wakho udinga ukuvelisa i-cortisol engaphezulu.
• Iihomoni ze-thyroid: I-Levothyroxine (umz., i-Synthroid®, i-Levoxyl®) ingasetyenziselwa ukunqongophala kwe-TSH. Umthamo wale mayeza uya kulungiswa ngokusekelwe kumanqanaba ehomoni yakho ye-thyroid.
• Iihomoni zokukhula: Ukuthatha iihomoni zokukhula kunokunceda ukugcina ubunzima bemisipha kunye noxinano lwamathambo.

Kwiimeko ezininzi, uya kunyangwa yi- endocrinologist , ugqirha ogxile kwiihomoni. Uya kwenza uvavanyo rhoqo ukuqinisekisa ukuba amanqanaba akho ehomoni akwinqanaba elifanelekileyo.

Ngaba isifo sikaSheehan singathintelwa?

Hayi, akukho nto unokuyenza ukuthintela iSheehan Syndrome. Iqela lakho lezonyango linokulawula kuphela ukopha kunye noxinzelelo lwegazi ngexesha lokubeleka kunye nokubeletha. Kodwa khumbula, iSheehan Syndrome yimeko engaqhelekanga kakhulu . Ukuba neqela lezonyango elinobuchule elinokuthintela iingxaki ezifana nokopha kakhulu ngexesha lokubeleka kunye nokubeletha kunciphisa kakhulu umngcipheko wakho wokuba nale meko.

Kuza kwenzeka ntoni ukuba ndineSheehan syndrome?

Ngonyango olufanelekileyo, umntu one-Sheehan syndrome unokulindela ukuchacha okuhle kakhulu.Uninzi lwabantu alubi neengxaki ezinkulu. Ngokujongwa ngokusondeleyo liqela lezonyango, abanye abantu baye bakwazi ukukhulelwa ngempumelelo emva kokuxilongwa. Kufuneka ubonane nengcali yakho ye-endocrinologist rhoqo ukuqinisekisa ukuba ufumana amayeza afanelekileyo okulungisa naluphi na ukungalingani kwamahomoni. Uvavanyo lwegazi rhoqo ukujonga amanqanaba akho amahomoni lukwayinxalenye yolu nyango lulandelayo.

Ingakanani ixesha lokuphila komntu one-hypopituitarism?

Ukuba une-Sheehan syndrome, ixesha olindeleke ukuba uliphile aliyi kutshintsha. Nangona uza kufuna unyango lobomi bonke, ungalindela ixesha olindeleke ukuba uliphile ubomi obuqhelekileyo.

Ndifanele ndimbone nini ugqirha?

Ukuba uneempawu zeSheehan syndrome, ingakumbi ukuba ukhe wopha kakhulu ngexesha lokubeleka , bonana nogqirha ngoko nangoko. Ugqirha wakho angenza uvavanyo ukuze abone ukuba unale meko.

Ndingaya nini kwigumbi likaxakeka?

Ukuba uneempawu zengxaki ye -adrenal , kuya kufuneka uye kwigumbi likaxakeka ngoko nangoko. Oku kunokuba yingozi ebomini ukuba akunyangwa. Ezi mpawu ziquka:

• Uziva unesizungu, ngathi uza kulahlekelwa zingqondo.
• Intlungu ebuhlungu esiswini, esifubeni esisezantsi, okanye emqolo.
• Ifiva.
• Umzimba ongenabomi.
• Isicaphucaphu nokuhlanza.
• Ukudideka okanye ukulahlekelwa zingqondo.

Ukuba ugqirha wakho ucinga ukuba usemngciphekweni, angakucela ukuba unxibe isongo sesilumkiso sezonyango ukuze ufumane unyango olukhawulezileyo xa kuvela imeko engxamisekileyo.

Ndingayibuza yiphi imibuzo ugqirha?

Ungabuza ugqirha wakho imibuzo efana nale:

• I-Sheehan syndrome iyichaphazela njani umzimba wam?
• Unyango luza kuziphucula njani iimpawu zam?
• Ngaba ungakhulelwa une-Sheehan syndrome?
• Kuza kufuneka ndenze uvavanyo lwegazi kangaphi?
• Ngawaphi amayeza okanye unyango olucebisayo?

Ukonakala kwe-pituitary gland kunokuchaphazela iinkqubo ezininzi zomzimba ezixhomekeke kumanqanaba e-hormone asempilweni. Unyango lokutshintshwa kwe-hormone lunokunceda ekusombululeni ezinye zeziphumo zokungabikho kwe-hormone. Thetha nogqirha wakho malunga nendlela i-Sheehan syndrome eya kuyichaphazela ngayo indlela ophila ngayo kunye nokuphila kakuhle. Kwakhona, xoxa ngokuba ugqirha wakho uza kujonga kangaphi amanqanaba e-hormone yakho ukuqinisekisa ukuba ufumana amayeza afanelekileyo kwimpilo yakho.

Okokugqibela, izinto ekufuneka uzikhumbule

I-Sheehan Syndrome yimeko engaqhelekanga ebangelwa kukonakala kwe-pituitary gland ngenxa yokopha kakhulu ngexesha lokubeleka. Oku kunokukhokelela kwiingxaki ezahlukeneyo zehomoni, kunye neempawu ezifana nobunzima bokuncancisa, ukuyeka ukuya exesheni, kunye nokudinwa kakhulu.

Eyona nto ingcono kukuba le meko inokulawulwa ngempumelelo ngonyango lwehomoni ubomi bonke kwaye ubomi obuqhelekileyo bunokufezekiswa.

Ukuba unale mpawu, ingakumbi ukuba ube neengxaki ngexesha lokubeleka, kubaluleke kakhulu ukufuna ingcebiso kagqirha. Ukuba ufunyenwe kwangethuba, ungaqala unyango kwaye uhlale usempilweni.

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Isifo sikaSheehan , i-pituitary gland, ukuzala, ukopha, iihomoni, impilo yabasetyhini, ukhathalelo lwasemva kokubeleka