Mhlawumbi wena okanye umntu osapho lwakho usandul’ ukufakelwa amalungu omzimba, njengesintso. Okanye mhlawumbi unyangwa ngengxaki engaqhelekanga yemiphunga. Kwezi meko, ugqirha wakho unokukunika iyeza elibizwa ngokuba yiSirolimus ukunceda ukulawula ukusebenza kwenkqubo yakho yokuzikhusela komzimba. Ngoko ke ekubeni eli liyeza elinzima kancinci, masithethe ngalo ngokulula nangokucacileyo, akunjalo?
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Kwenzeka ntoni ngokwenene ngale mithi?
Ngamafutshane, iSirolimus liyeza elinciphisa okanye elicinezela ukusebenza kwenkqubo yomzimba wakho yokuzikhusela. Cinga ngale ndlela: xa umntu efumana utyando olutsha lwesitho, umzimba wethu ulubona "njengento yangaphandle." Ngoko ke inkqubo yokuzikhusela yomzimba izama ukuhlasela isitho esitsha, okanye ukusala. ISirolimus iyayeka ukwaliwa. Ikwanceda ukulawula ukukhula okungaqhelekanga kweeseli emiphungeni, isifo esingaqhelekanga semiphunga esibizwa ngokuba yi-lymphangioleiomyomatosis.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uthathe amayeza
Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukwazisa ugqirha wakho ngemeko yakho yempilo epheleleyo. Qiniseka ukuba uyamxelela ukuba unayo nayiphi na kwezi meko zilandelayo:
- Isifo seswekile
- Isifo sentliziyo
- Amanqanaba aphezulu e-cholesterol okanye i-triglycerides egazini
- Nasiphi na isifo esikhoyo ngoku
- Izifo zesibindi
- Ukuba une-allergy kwi-sirolimus okanye nakweyiphi na enye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa
Ukunika ugqirha wakho olu lwazi kubalulekile ekukunikeni unyango olufanelekileyo nolukhuselekileyo.
Ndingayisebenzisa njani kanye kanye le yeza?
Eli liyeza eliza likwimo engamanzi, ngoko ke kufuneka ulandele la manyathelo kanye xa ulisebenzisa.
1. Sebenzisa isirinji echanekileyo: Sebenzisa isirinji e-amber kuphela eza neyeza. Musa ukulinganisa ngeepuni zasekhitshini, kuba aziyi kukunika idosi echanekileyo. Sebenzisa isirinji entsha kwidosi nganye uze uyilahle emva kokusebenzisa.
2. Ukuxuba amayeza: Beka ubungakanani obulinganisiweyo beyeza kwiglasi okanye kwikomityi yeplastiki. Yongeza iimililitha ezingama-60 (malunga nee-ounces ezi-2) zamanzi okanye ijusi yeorenji kuyo. Ungaze udibanise nejusi yegrapefruit okanye naluphi na olunye ulwelo.
3. Ukusela: Xuba kakuhle uze usele ngoko nangoko.Sela. Emva koko, yongeza amanye ama-milliliters ali-120 (malunga nee-ounces ezi-4) zamanzi okanye ijusi yeorenji kwikomityi enye, uvuselele kwakhona, uze usele nayo. Oku kuya kunceda ukukhupha naliphi na iyeza eliseleyo kwikomityi.
4. Yithathe ngexesha elifanelekileyo: Ziqhelise ukusela amayeza akho ngexesha elifanayo yonke imihla. Ungayithatha nokuba utye okanye utye ngaphandle kokutya, kodwa namathela kwindlela enye. Umzekelo, ukuba uyisebenzisa emva kokutya yonke imihla, yenza ngaloo ndlela.
5. Ukuba uthatha iCyclosporine: Ukuba uthatha iCyclosporine, kufuneka uthathe iSirolimus emva kweeyure ezi-4 uyithathile.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Kodwa ukuba sele kusondele ixesha lomthamo wakho olandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe idosi ephindwe kabini.
Amayeza ekungafanelekanga ukuba asetyenziswe neSirolimus kwaye ekufuneka uwalumkele
I-Sirolimus liyeza elinokusetyenziswana namanye amayeza, ngoko ke kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amanye amayeza owasebenzisayo.
| Iintlobo zamayeza kunye nemiphumo yawo | |
|---|---|
| ❌ Izinto ongafanele uzithathe ngeSirolimus | |
| Ii-antibiotics | NjengeClarithromycin, iErythromycin, iTelithromycin |
| Izinto ezilwa nokungunda | Njenge-Itraconazole, iKetoconazole, iVoriconazole |
| Okunye | Ijusi yegrapefruit, iMifepristone, iRifampin, iRifabutin |
| ⚠️ Amayeza afanele asetyenziswe ngononophelo, emva kokwazisa ugqirha | |
| I-Cyclosporine, i-Diltiazem, i-Verapamil (yoxinzelelo lwegazi), i-Carbamazepine, i-Phenytoin (yokuxinwa), i-St. John's wort (iyeza lemifuno), amayeza ahlukeneyo okugonya, kunye namanye amayeza amaninzi. | |
Kubalulekile: Olu luhlu aluphelelanga. Xelela ugqirha wakho ngazo zonke izinto ozithathayo, kuquka iivithamini, amayeza esintu, kunye namayeza athengiswa ngaphandle kwemvume kagqirha.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa amayeza
- Ukuhlolwa rhoqo kwezonyango: Qhubeka usiya kwiikliniki njengoko ugqirha wakho ekuyalele. Kusenokufuneka ukuba wenze uvavanyo lwegazi rhoqo ukuze ujonge imeko yakho.
- Ukukhuselwa kwiintsholongwane: Eli yeza linciphisa amasosha omzimba wakho, ukuze ukwazi ukufumana izifo ezifana nomkhuhlane kunye nomkhuhlane ngokulula. Ngoko ke, hlala kude neendawo ezinabantu abaninzi kunye nabantu abagulayo. Ukuba ubonakalisa iimpawu zosulelo (umkhuhlane, umphimbo obuhlungu), musa ukuzinyanga kwaye utsalele umnxeba ugqirha wakho ngoko nangoko.
- Amanqanaba e-cholesterol kunye neswekile: Eli yeza linokunyusela amanqanaba e-cholesterol kunye neswekile egazini lakho. Ugqirha wakho uza kujonga oku aze akunike unyango olwahlukileyo ukuba kuyimfuneko.
- Ukukhuselwa lilanga: Ulusu lwakho luya kuba novelwano kakhulu kukukhanya kwelanga (luya kuba novelwano kwifoto) ngelixa usebenzisa eli yeza. Ngoko ke, ukuba uphuma elangeni, nxiba impahla ende kwaye usebenzise i-sunscreen efanelekileyo.
- Umngcipheko womhlaza: Ngenxa yokuxinana komzimba ixesha elide, kunokubakho umngcipheko okhulayo kancinci weentlobo ezithile zomhlaza (ingakumbi umhlaza wolusu). Musa ukukhathazeka ngale nto, kodwa thetha nogqirha wakho ngayo.
- Ukuthintela ukukhulelwa: Ukuba ungumfazi osemdala wokuzala, kufuneka usebenzise uhlobo lokulawula ukukhulelwa olusebenza kakuhle ngelixa usebenzisa eli yeza kwaye kangangeeveki ezili-12 emva kokuyeka ukusebenzisa eli yeza .
Iziphumo ebezingalindelekanga ezinokubakho
Njengayo nayiphi na iyeza, iSirolimus inokubangela iziphumo ebezingalindelekanga. Ezinye zezi ziyingozi, ngelixa ezinye zixhaphakile.
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ngoko nangoko | |
|---|---|
| Iimpawu ze-aleji | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, okanye ulwimi |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, umphimbo obuhlungu |
| Ezinye iimpawu ezinzulu | Umchamo omnyama, ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo, ukuquleka, uxinzelelo lwegazi oluphezulu, ubomvu, amabala amancinci eluswini, ukudumba okungaqhelekanga, ubunzima bokuchama, ukopha okanye ukukrweleka okungaqhelekanga, ukudinwa kakhulu. |
| Iimpawu zamanqanaba aphezulu eswekile | Unxano okanye indlala egqithisileyo, ukuchama rhoqo, ukudinwa kakhulu, ukubona izinto ezingaqhelekanga. |
| Izinto ekufuneka zixelwe ukuba ziyaqhubeka okanye ziyakhathaza | |
| Iintlungu zomzimba, amaqhakuva, ukudumba, isicaphucaphu, ukuhlanza, iintlungu zesisu, izandla ezingcangcazelayo, ukungalali. | |
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lwePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Indlela yokugcina iyeza ngokuchanekileyo?
- Gcina ibhotile yamayeza efrijini (phakathi kwe-2 kunye ne-8 degrees Celsius). Musa ukuyigcina efrijini. Khusela ekukhanyeni.
- Lahla nayiphi na iyeza eseleyo zingadlulanga iintsuku ezingama-30 emva kokuvula ibhotile.
- Ukuba kufuneka ibhotile evuliweyo, ingagcinwa kubushushu begumbi (ngaphantsi kwama-25 Celsius) ukuya kuthi ga kwiintsuku ezili-15.
- Sebenzisa idosi efakwe kwisirinji zingadlulanga iiyure ezingama-24. Ingagcinwa efrijini okanye kubushushu begumbi. Yilahle ukuba ayisetyenziswanga zingadlulanga iiyure ezingama-24.
- Gcina kude nokufikelela kwabantwana.
Umyalezo Wokuya Ekhaya
- I-Sirolimus liyeza elibaluleke kakhulu. Lithathe kanye njengoko ugqirha wakho ekuxelele, ngedosi efanelekileyo, ngexesha elifanelekileyo.
- Eli yeza lelakho kuphela. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo kunye nazo zonke iimeko zempilo onazo.
- Zikhusele kwiintsholongwane. Lumka elangeni.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu, funa ingcebiso kagqirha ngoko nangoko.
- Ungaphoswa ziintlanganiso zikagqirha wakho. Zibaluleke kakhulu kwimpilo yakho.
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