Usenokuba awuzange uve nge-SAM-e (ebizwa ngokuba yi-SAM-e) ngaphambili. Kodwa ubusazi na ukuba le yikhemikhali ebaluleke kakhulu eveliswa ngokwemvelo emzimbeni wakho, owakho nowam, umzuzwana ngamnye wemihla ngemihla. Ngamafutshane, ibalulekile ekusebenzeni okuqhelekileyo kwemizimba yethu. Imizimba yethu iyivelisa rhoqo, yonke imihla, umzuzwana ngamnye.
Yintoni kanye kanye eyenziwa yi-SAM-e emizimbeni yethu?
Khawucinge ukuba umzimba wethu yinkampani enkulu. Umsebenzi ngamnye kule nkampani kufuneka uthumele imiyalezo. 'Abathunywa' abathwala le miyalezo phakathi kweeseli zemithambo-luvo yileyo siyibiza ngokuba zii-neurotransmitters . Kufana nomntu ohambisa iileta eofisini. Ngoko ke kukho inkqubo ebaluleke kakhulu eyenzeka kuwo wonke umzimba enceda ekwenzeni ezi neurotransmitters, kwaye siyibiza ngokuba yi-methylation . Umsebenzi ophambili we-SAM-e kukuncedisa kule nkqubo ye-methylation.
Nangona imizimba yethu ivelisa oku, ngamanye amaxesha kusenokunganeli. Kulapho abanye abantu bakusebenzisa njengesongezelelo . Nangona ifumaneka njengesongezelelo kumazwe anjengeMelika, ikwanikwa njengeyeza elinikwa ngugqirha kwamanye amazwe aseYurophu. Igama layo lesayensi yi-S-adenosylmethionine.
Kutheni ke abantu besebenzisa i-SAM-e?
Abantu abaninzi bakhetha ukusebenzisa into evakala ngathi 'yendalo' kwaye 'ithambile kancinci' kuneyeza lemveli laseNtshona. Kuba bacinga ukuba ekubeni yinto eyenziwa ngumzimba ngokwawo, akuyi kubakho miphumo mibi. Kwabo bantu, i-SAM-e yindlela ekhangayo.
I-SAM-e ixutyushwa kakhulu ngokunxulumene neemeko ezimbini zonyango: i-osteoarthritis kunye nokudakumba.
I-Osteoarthritis
Ezinye izifundo zifumanise ukuba i-SAM-e inokunceda ekunciphiseni iintlungu, ingakumbi kwi -osteoarthritis yedolo okanye isinqe. Ezinye izifundo zibonise ukuba i-SAM-e isebenza kakuhle njengeziyobisi ezichasene nokuvuvukala (ii-NSAID) ezifana ne -ibuprofen okanye i-celecoxib ekunciphiseni iintlungu nokuphucula ukuhamba kwamalungu. Nangona isenokungasebenzi ngokukhawuleza njengamayeza, kuthiwa ineziphumo ebezingalindelekanga ezimbalwa . Oku kungenxa yokuba i-SAM-e inokunciphisa umsebenzi weekhemikhali ezithile emzimbeni ezibangela ukudumba kunye nentlungu.
Uxinzelelo
Abanye abantu abanesifo sokudakumba bafunyenwe benamanqanaba aphantsi e-SAM-e. Amanye amayeza okudakumba ajolise kwii-neurotransmitters engqondweni, ezifana ne -serotonin , i-norepinephrine , kunye ne-dopamine .Abaphandi bakholelwa ukuba i-SAM-e inokukhuthaza.
Kodwa uninzi lwezifundo ezenziweyo ngale nto zincinci kwaye zezexesha elifutshane. Ngoko ke akukabonakali ngokupheleleyo ukuba isebenza kangakanani na kwi-depression. Nangona abanye abantu besebenzisa i-SAM-e kunye ne-antidepressants, akukho nzuzo icacileyo yokwenza njalo.
Into ebalulekileyo kukuba i-SAM-e ayisiyonto imangalisayo. Ukuba uyisebenzisa, kufuneka ibe yinxalenye enye yesicwangciso sonyango ngokubanzi. Oko kukuthi, kufuneka ihambisane nezinye iindlela zonyango, ezifana nokutya kunye nokuzilolonga.
Ukongeza kwezi zimbini, abanye abantu bayisebenzisela neemeko ezifana ne -intrahepatic cholestasis , isifo sika-Alzheimer , i-fibromyalgia , kunye ne-migraine , kodwa uphando alukabikho ngokwaneleyo ngale nto okwangoku.
Ukuba ndisebenzisa i-SAM-e, ndifanele ndithathe malini?
Akukho dosi ithile yoku. Iyahluka kumntu nomntu, kuxhomekeke kwisifo. Umzekelo, iimiligram ezingama-400-600 ngosuku zokudakumba, kunye neemiligram ezingama-600-1200 ngosuku (zahlulwe zibe ziidosi ezintathu) ze- osteoarthritis ziye zasetyenziswa kwizifundo.
Kodwa ngokuqinisekileyo kuya kufuneka uthethe nogqirha wakho malunga nokuba oku kulungile na kuwe kunye nokuba kufuneka uthathe malini. Ugqirha wakho unokukucebisa ukuba unyuse umthamo kancinci kancinci ukuze unciphise iziphumo ebezingalindelekanga ezifana nokungaphumli kunye nokuxhalaba .
Ngaba kukho umngcipheko wokusebenzisa oku?
I-SAM-e ithathwa njengekhuselekileyo, kodwa uninzi lwezifundo bezisebenza ixesha elifutshane, ngoko ke akukho bungqina buncinci bokhuseleko lwayo ekusetyenzisweni kwayo ixesha elide.
Iziphumo ebezingalindelekanga azibi kakhulu. Ezona ziphumo bezingalindelekanga zixhaphakileyo zezi:
| Iziphumo Eziqhelekileyo Ze-SAM-e | |
|---|---|
| - Ukuphazamiseka kwesisu, isicaphucaphu | - Urhudo okanye ukuqhinwa |
| - Umlomo owomileyo | - Intloko ebuhlungu kunye nesiyezi |
| - Ixhala kunye nokungazoli | - Ukubila |
| - Ukudumba (iGesi) | - Ukungalali |
Iimeko ekufuneka uzilumkele ngakumbi
Abanye abantu banokucinga ukuba ukuthatha ezi zinto ngaphandle kokuthetha nogqirha kulungile kuba iziphumo ebezingalindelekanga zincinci. Kodwa yimpazamo enkulu leyo. Ukusebenzisa i-SAM-e kunokuba yingozi, ingakumbi ukuba uthatha amanye amayeza okanye izongezo.
| Ngubani/nini apho umntu afanele alumke khona? | Iyintoni ingozi? |
|---|---|
| Abantu abasebenzisa unyango lokudakumba (ingakumbi abo bathatha ezinye izidambisi-ntlungu okanye izongezo ezifana ne-St. John's wort) | Iziphumo ezidibeneyo zala mayeza omabini zinokubangela amanqanaba aphezulu e-serotonin emzimbeni (iSerotonin Syndrome). |
| Abantu abanesifo se-bipolar | Oku kunokuyenza mandundu imeko yabo yokusebenza ngokugqithisileyo kunye novuyo (iMania/Hypomania). |
| Oomama abakhulelweyo nabancancisayo | Kuphephe ukuthatha ngaphandle kwemvume kagqirha wakho, kuba akukho datha yaneleyo malunga nokhuseleko. |
| Abantwana abancinci | Ayikhuthazwa ebantwaneni. |
| Abantu abasebenzisa amanye amayeza (okukhwehlela, iintlungu, isifo seswekile, isifo sikaParkinson, ii-MAOIs) | Ingcebiso kagqirha ibalulekile kuba kunokwenzeka ukuba kubekho unxibelelwano olungafunekiyo nalo mayeza. |
Ukuba uthenga isongezelelo se-SAM-e, qiniseka ukuba ujonga umgangatho waso. Kungcono ujonge iimpawu zomgangatho ezifana ne-US Pharmacopeia (USP) okanye i-Good Manufacturing Practice (GMP) kwileyibhile.
Imibuzo Ebuzwa Rhoqo (Ii-FAQ)
- Ngaba i-SAM-e ibangela ukulahleka kweenwele?
Hayi, i-SAM-e ayibikwanga ukuba ibangela ukulahleka kweenwele.
- Kuthatha ixesha elingakanani ukubona iziphumo?
Kudla ngokuthatha iiveki ezimbalwa ukuze uzive naluphi na utshintsho.
- Ngaba i-SAM-e ikwenza ube mkhulu?
Hayi, akukho sizathu sokukholelwa ukuba i-SAM-e ibangela ukutyeba.
- Ngaba i-SAM-e ikwenza uzive ungcono?
Ewe, xa oku kuphumelele kwingxaki yokudakumba, abanye abantu baziva ngathi banamandla angakumbi. Oko kungaba ngamandla amahle navelisayo. Kodwa kwabanye, kunokuvakala ngathi kukuxhalaba okanye ukungazinzi.
- Awukwazi ukufumana i-SAM-e ekutyeni?
Hayi, akukho kutya kuqulethe i-SAM-e. Yinto eyenziwa ngumzimba ngokwawo.
Umyalezo Wokuya Ekhaya
- I-SAM-e yikhompawundi eyenzeka ngokwendalo emizimbeni yethu kwaye ibalulekile ekusebenzeni komzimba nakwimo yeemvakalelo.
- Nangona isetyenziswa njengesongezelelo seentlungu zamalungu kunye nokudakumba, kusekho ubungqina obuncinci besayensi bokusebenza kwayo.
- Nangona iziphumo ebezingalindelekanga zihlala zincinci, kunokubakho iingozi kwabanye abantu kwaye xa zithathwa kunye namanye amayeza.
- Ungaze uqale ukusebenzisa i-SAM-e ngaphandle kwengcebiso kagqirha, ingakumbi ukuba uthatha amayeza enye imeko, okanye ukuba ukhulelwe okanye uncancisa.
- Njengayo nayiphi na isongezelelo, esi sixhobo kufuneka sisetyenziswe kuphela phantsi kwesikhokelo sikagqirha wakho.
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