Ngaba ufuna ukwazi okungakumbi ngeeTablethi zeTofacitinib Extended-release? Nazi iimpendulo zemibuzo yakho!

Ngaba wena okanye umntu omaziyo unikwe iTofacitinib ngugqirha? Okanye ukhe weva ngeli yeza ndaweni ithile waza weza apha ukuze ufunde okungakumbi ngalo? Nangona kunjalo, kweli nqaku, siza kuthetha ngeepilisi zeTofacitinib ezikhutshwa ixesha elide ngendlela elula neqondakalayo. Siza kujonga izinto ezininzi, ezifana nokuba le yeyiphi na, indlela yokuyisebenzisa, kunye noko kufuneka ukuqaphele.

Ngoko ke, yintoni iTofacitinib?

Ngamafutshane, iTofacitinib liyeza elisetyenziselwa ukunyanga iimeko ezithile. Isetyenziswa kakhulu uku:

• I-Rheumatoid Arthritis: Olu luhlobo lwe-arthritis olubangela ukudumba, iintlungu zamalungu kwaye luhlala ixesha elide.
• I-Psoriatic Arthritis: Olu luhlobo lwe-arthritis. Ngamanye amaxesha luyenzeka nakubantu abane-psoriasis.
• I-Polyarticular Juvenile Idiopathic Arthritis: Olu luhlobo lwe-arthritis oluchaphazela amalungu amaninzi kwaye luyenzeka kubantwana abancinci.
• I-Ankylosing Spondylitis: Le yimeko yokuvuvukala echaphazela kakhulu amalungu omqolo.
• I-Ulcerative Colitis: Esi sisifo sokudumba esihlala ixesha elide esibangela izilonda kulwelo lwamathumbu amakhulu.

Eli yeza lisebenza ngokusebenza kumasosha omzimba wakho. Amasosha omzimba wethu ahlala esikhusela kwizifo. Kodwa ngamanye amaxesha le nkqubo idla ngokusebenza kakhulu ize iqale ukuhlasela iiseli zomzimba wethu. Kulapho ke ezi zifo zikhankanyiweyo apha ngasentla zenzeka khona. Iyeza elibizwa ngokuba yiTofacitinib likwiqela lamayeza abizwa ngokuba yiJAK inhibitors . Lisebenza ngokulawula ezinye zezinto ezingalunganga kumasosha omzimba. Emva koko iimpawu ziqala ukwehla.

Eli yeza lingasetyenziswa noogqirha kwezinye iimeko, ngoko ke ukuba unemibuzo, kungcono ubuze ugqirha wakho okanye ingcali yezonyango.

Igama eliqhelekileyo lemveliso yale mithi yiXeljanz XR .

Yintoni omele uyixelele ugqirha wakho ngaphambi kokuba uqale eli yeza?

Kulungile, ngoku makhe sibone ukuba yintoni ekufuneka uyixelele ugqirha wakho okanye umongikazi ngaphambi kokuba uqale ukuthatha iTofacitinib. Ezi zibaluleke kakhulu, kuba eli yeza alifanelekanga kuye wonke umntu. Ukuba unenye okanye ngaphezulu kwezi meko zilandelayo, kufuneka uxelele ugqirha wakho :

• Amahlwili egazi: Ngaba wakha waba namahlwili egazi emithanjeni yakho ngaphambili? Okanye ngaba kukho umntu kusapho lwakho owakha waba nawo?
• Umhlaza:Ngaba wakha waba nomhlaza, okanye kukho umntu kusapho lwakho onomhlaza? Ngaba ugqirha ukuxelele ukuba usemngciphekweni wokuba nomhlaza?
• Isifo seswekile (oko kuthetha isifo seswekile): Ngaba unesifo seswekile?
• Isifo sentliziyo: Ngaba unesifo sentliziyo?
• Uxinzelelo lwegazi oluphezulu: Ngaba unoxinzelelo lwegazi oluphezulu?
• I-cholesterol ephezulu: Ngaba unamanqanaba aphezulu e-cholesterol egazini lakho?
• I-HIV okanye i-AIDS: Ngaba kukho isifo esinciphisa amajoni omzimba anje?
• Iingxaki zenkqubo yomzimba yokuzikhusela: Ngaba unazo ezinye izifo ezinxulumene nenkqubo yomzimba yokuzikhusela?
• Iintsholongwane: Ngaba ufumana iintsholongwane rhoqo? Ingakumbi iintsholongwane ezifana ne-chickenpox, izilonda zomkhuhlane, i-herpes, kunye ne-hepatitis B.
• Isifo sephepha (TB) okanye ezinye izifo ezibangelwa yibhaktiriya, ifungus, okanye iintsholongwane: Ngaba unesifo sephepha okwangoku, ngaba wakha wasifumana, okanye wakha wanyangwa?
• Isifo sezintso: Ngaba kukho ingxaki ngezintso zakho?
• Isifo sesibindi: Ngaba kukho isifo sesibindi?
• Amanani egazi aphantsi: Ngaba unengxaki yokubala iiseli ezimhlophe zegazi, iiplatelet, okanye iiseli ezibomvu zegazi eziphantsi?
• Isifo semiphunga okanye sokuphefumla: Ngaba unengxaki yokuphefumla efana ne-asthma okanye i-COPD?
• Ukufakelwa amalungu omzimba: Ngaba wakha wafakelwa amalungu omzimba?
• Ukutshaya iicuba: Ngaba uyatshaya iicuba?
• Iingxaki zesisu okanye zamathumbu: Ngaba unayo nayiphi na ingxaki efana nezilonda zesisu?
• I-allergy reaction kwi-tofacitinib okanye kwamanye amayeza, ukutya, iidayi okanye izithinteli: Ngaba wakha waba ne-allergy reaction kweli yeza okanye nantoni na enye?
• Ukuba ukhulelwe okanye uzama ukukhulelwa: Oku kubaluleke kakhulu.
• Ukuba uncancisa: Xelela ugqirha wakho ngale nto.

Olu luhlu lude kancinci, kodwa konke kungenxa yokhuseleko lwakho.

Ulisebenzisa njani kanye kanye eli yeza?

Eli yeza lifanele lithathwe ngomlomo ngamanzi . Kungcono ukulithatha ngexesha elifanayo yonke imihla , njengoko ugqirha wakho ekuxelele.

Kubalulekile: Musa ukuyisika, ukuyityumza, okanye ukuyihlafuna le pilisi. Ginya yonke.

Ungayithatha le mithi nokuba utya okanye ungenaso. Nangona kunjalo, ukuba uziva isisu sibuhlungu, yithathe nokuba utya. Ufanele uqhubeke uthatha le mithi de ugqirha wakho akuxelele ukuba uyeke.

Xa unikwa eli yeza yikhemesti, uya kunikwa nencwadana yemiyalelo ekhethekileyo (iMedGuide) . Kufuneka ulifunde eli phepha ngononophelo ngalo lonke ixesha usela iyeza, naxa ufumana ukuphinda ulizalise. Liqulethe ulwazi olubalulekileyo.

Kufuneka kuqatshelwe ngokukodwa xa kunikwa abantwana abancinci eli yeza, ngoko ke thetha nogqirha womntwana wakho ngalo.

Ukugqithisa amayeza: Ukuba ucinga ukuba uwasele kakhulu la mayeza, fowunela isebe likaxakeka lesibhedlele elikufutshane okanye iziko lolawulo lwetyhefu ngokukhawuleza.

Enye into: Eli yeza lelakho wedwa. Musa ukwabelana ngalo nabanye, kulungile?

Wenza ntoni ukuba uphoswe yintlanganiso yamayeza?

Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba sele kuza kufuneka uyithathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe idosi ephindwe kabini.

Ngawaphi amanye amayeza anokusebenza kunye nale mithi?

Eli linqaku elibaluleke kakhulu. Amanye amayeza anokubangela iingxaki xa esetyenziswa kunye neTofacitinib.

Musa ukuthatha iTofacitinib kunye namayeza alandelayo:

• I-Upadacitinib

Ukongeza, la mayeza alandelayo anokusebenzisana neTofacitinib (oko kuthetha ukuba anokubangela iziphumo ebezingalindelekanga):

• Amanye amayeza e-antiviral e-hepatitis, i-HIV, okanye i-AIDS
• I-Azathioprine
• Amanye amayeza e-biologic (imizekelo: abatacept, adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, ofatumumab, rituximab, sarilumab, secukinumab, tocilizumab, ustekinumab, vedolizumab)
• Amanye amayeza osulelo lwefungus (imizekelo: i-fluconazole, i-itraconazole, i-ketoconazole, i-voriconazole )
• Amanye amayeza asetyenziselwa ukunyanga izifo ezifana nesifo sokuwa (i-fits) (imizekelo: i-carbamazepine, i-phenobarbital, i-phenytoin )
• I-Cyclosporine
• Iigonyo eziphila ( ezinye iigonyo akufuneki zinikwe ngelixa usela eli yeza)
• Amayeza anciphisa amandla omzimba wakho okulwa nosulelo
• I-Rifampin (iyeza lesifo sephepha)
• Ezinye izongezo, umzekelo iSt. John's wort
• I-Tacrolimus

Olu luhlu alubandakanyi onke amayeza. Ngoko ke, xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo, kuquka amayeza aqhelekileyo, iivithamini, amayeza athengiswa ngaphandle kwemvume kagqirha, amayeza esintu, kunye nezongezo zokutya.Kwakhona, ukuba utshaya icuba, usela utywala, okanye usebenzisa ezinye iziyobisi, kufuneka ubaxelele ngazo, kuba ezinye izinto zinokuchaphazela eli yeza.

Yintoni endifanele ndiyilumkele xa ndisebenzisa eli yeza?

Ngelixa usela eli yeza, ugqirha wakho uza kujonga impilo yakho rhoqo (ukuhlolwa rhoqo) . Yiya kuloo ma-aphoyintimenti rhoqo. Xelela ugqirha wakho ukuba iimpawu zakho aziphucuki okanye ukuba zibonakala zisiba mandundu.

Kuya kufuneka wenze umsebenzi wegazi ngelixa usebenzisa eli yeza.

Enye into kukuba, inxalenye yokwaleka yale yeza ayinyibiliki. Yinto eqhelekileyo leyo. Ungayibona inxalenye yokwaleka yepilisi iphuma kunye nendle yakho. Ungakhathazeki ngayo. Ayiyongxaki. Inxalenye yonyango yeyeza ifunxwe emzimbeni.

Eli yeza linokunyusa kancinci umngcipheko wakho wokufumana usulelo. Ke ngoko, ukuba ubonakalisa iimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, okanye impumlo egobhozayo, musa ukuzinyanga kwaye ufune iingcebiso zonyango. Zama ukuhlala kude nabantu abagulayo.

Musa ukuthatha amayeza okunciphisa umkhuhlane nathomalalisa iintlungu afana ne -aspirin, i-acetaminophen, i-ibuprofen, i-naproxen, kunye ne-ketoprofen ngaphandle kwengcebiso kagqirha wakho. La mayeza anokunciphisa umkhuhlane kwaye enze kube nzima ukubona usulelo.

Thetha nogqirha wakho malunga nomngcipheko wakho womhlaza . Ukusela eli yeza kunokunyusa kancinci umngcipheko wakho wokuba neentlobo ezithile zomhlaza.

Ingqwalasela ekhethekileyo malunga nokukhulelwa nokuncancisa:

Musa ukukhulelwa ngelixa usebenzisa eli yeza. Ukuba uceba ukukhulelwa okanye ucinga ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko. Oku kunokubangela ingozi enkulu kumntwana wakho ongekazalwa. Cela ugqirha wakho ukuba akunike ulwazi oluthe kratya.

Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye ubuncinane iiyure ezingama-36 emva kokuba uyekile ukusebenzisa eli yeza.

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Kulungile, masithethe ngeziphumo ebezingalindelekanga abanye abantu abanokuzifumana xa besebenzisa eli yeza. Asinguye wonke umntu ozifumanayo ezi, kodwa kulungile ukuzazi.

Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko:

Ukuba ufumana naziphi na kwezi mpawu, bonana nogqirha ngokukhawuleza:

• Iimpendulo ze-allergy: ukurhawuzelela kwesikhumba, ukurhawuzelela, okanye ukudumba kobuso, imilebe, okanye ulwimi.
• Ukuqhekeka kwegazi: Iintlungu zesifuba; ubunzima bokuphefumla; iintlungu zomlenze, ukudumba, okanye ukuziva ufudumele.
• Ukuhlaselwa yintliziyo: Ubunzima bokuphefumla; iintlungu okanye ukuqina esifubeni, entanyeni, emqolo, okanye ezingalweni; ukuziva ubuthathaka okanye udiniwe ngendlela engaqhelekanga.
• Usulelo:Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu okanye ubunzima bokuchama.
• Isitulo esinombala okhanyayo.
• Ukulimala kwesibindi: umchamo otyheli okanye omdaka; ukuziva ungaphilanga kakuhle okanye iimpawu ezifana nomkhuhlane; ukuphelelwa ngumdla wokutya, iintlungu esiswini esingaphezulu ngasekunene; ubuthathaka okanye ukudinwa okungaqhelekanga, ukutyheli kwamehlo okanye ulusu.
• Inani leeseli ezibomvu zegazi ezisezantsi: Ukuphelelwa ngumphefumlo; ukutyhafa; ukuziva unesizungu okanye intloko ebuhlungu; ubuthathaka okanye ukudinwa okungaqhelekanga.
• Istroke: Ukutshintsha kombono; ukudideka; ubunzima bokuthetha okanye ukuqonda; intloko ebuhlungu kakhulu; ukudinwa okanye ubuthathaka ngequbuliso ebusweni, engalweni, okanye emlenzeni; ubunzima bokuhamba; isiyezi; ukulahleka kokulinganisela.
• Iinyembezi esiswini okanye emathunjini: umkhuhlane; iintlungu zesisu; utshintsho olukhawulezileyo kwindlela yokuzilungisa.

Ngokwesiqhelo akukho ngxaki inkulu, kodwa ukuba iyaqhubeka, nazi izinto onokuzixelela ugqirha wakho :

Ezi azisoloko zimbi kakhulu, kodwa ukuba ziyaqhubeka zikukhathaza, xelela ugqirha wakho :

• Urhudo
• Intloko ebuhlungu
• Intlungu yemisipha
• Ukuxinana kwempumlo - impumlo egobhozayo okanye exineneyo

Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona nantoni na engaqhelekanga ukongeza kwezi, nceda ubuze ugqirha wakho ngayo.

Ndingaligcina njani iyeza? Ndenza ntoni ukuba kukho eliseleyo?

Gcina eli yeza kude nabantwana kunye nezilwanyana zasekhaya .

Gcina kubushushu begumbi (phakathi kwama-20 nama-25 degrees Celsius, phakathi kwama-68 nama-77 degrees Fahrenheit) . Musa ukusebenzisa amayeza aphelelwe lixesha. Afanele alahlwe.

Indlela yokulahla amayeza angasetyenziswanga naphelelwe lixesha:

• Nika amayeza kwinkqubo yokubuyisela amayeza. Ungabuza ikhemesti yakho okanye amapolisa ngendawo enjalo.
• Ukuba awukwazi ukuyibuyisela ngaloo ndlela, jonga ileyibhile okanye iphakheji ukuze ubone ukuba eli yeza lifanele lilahlwe okanye lihlanjwe kwindlu yangasese. Ukuba awuqinisekanga, buza ugqirha wakho okanye ikhemisti.
• Ukuba ungayilahla enkunkuma, khupha iyeza ebhotileni/epakethini, ulixube nento efana nenkunkuma yekati, umhlaba, okanye ikofu, uyifake ebhegini okanye kwisikhongozeli esivalwe kakuhle, uze uyilahle enkunkuma.

Eyona nto ibalulekileyo - khumbula! (Umyalezo oya nawo ekhaya)

I-Tofacitinib inokuba liyeza eliluncedo kakhulu, kodwa kuphela xa isetyenziswa ngokuchanekileyo.

• Soloko usela amayeza akho kanye njengoko ugqirha wakho ekuxelele.
• Unantoni?Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, xelela ugqirha wakho ngazo.
• Eli yeza lelakho wedwa, ungaliniki abanye.
• Ukuba unemibuzo okanye amathandabuzo, ungabi namahloni okubuza ugqirha wakho okanye ikhemisti .

Eli phepha lolwazi lisisishwankathelo kuphela. Lisenokungabi nazo zonke iinkcukacha. Ukuba unemibuzo engaphezulu malunga nale yeza, nceda uthethe nogqirha wakho, usokhemesti, okanye umboneleli wezempilo.

I- Tofacitinib, i-Tofacitinib, i-Xeljanz XR, isifo samathambo, ukudumba kwamalungu, i-JAK inhibitor, inkqubo yomzimba yokuzikhusela, i-ulcerative colitis