Mhlawumbi ukhe weva nge-hormone ye-insulin. Eli gama livela kakhulu, ingakumbi xa kuthethwa ngesifo seswekile. Kodwa ngaba wakha weva nge-hormone ye-insulin-like growth factor-1, okanye i-IGF-1 ngamafutshane? Yi-hormone ekwanxulumene ne-insulin, kwaye isebenza njenge-insulin. Namhlanje, masithethe ngokuba yi-IGF-1 kwaye inxulumene njani nesifo seswekile.
Ngamafutshane, yintoni i-IGF-1?
I-'Insulin-like Growth Factor-1' okanye i-'IGF-1' yi-hormone ebaluleke kakhulu eveliswa sisibindi sethu. Omnye wemisebenzi yayo ephambili kukubonisa amathambo nezihlunu zethu ukuba "zikhule ngokufanelekileyo." Oko kuthetha ukuba ibalulekile ekukhuleni kwemizimba yethu.
Le hormone ifana kakhulu ne-insulin. Ikwachaphazela indlela iiseli zethu ezisebenzisa ngayo iswekile, okanye i-glucose, egazini lethu. Ngoko ke ngoku ungabona ukuba kukho unxibelelwano olukhulu phakathi kwezi zimbini.
Ulwalamano neSifo seswekile sohlobo lwesibini
Okokuqala, masikhumbule indlela isifo seswekile esikhula ngayo. Ihomoni i-insulin inceda i-glucose esiyifumana ekutyeni esikutyayo ukuba ingene kwiiseli zethu ize yenze amandla. Cinga ngayo njengokuba i-insulin ifana nesitshixo, iseli ifana negumbi, kwaye ucango lweseli luyitshixo. Ngoko ke, xa esi sitshixo (i-insulin) sifakiwe kwaye itshixo livuliwe, i-glucose ingangena kwiseli.
Kodwa ngamanye amaxesha imizimba yethu ayiphenduli kakuhle kule insulin. Siyibiza ngokuba yi -insulin resistance . Ifana ne-lock enomhlwa engenakujikwa yisitshixo. Emva koko i-pancreas yethu izama ukwenza i-insulin engaphezulu ukuze yenze umsebenzi. Kodwa ngaxa lithile, nayo ayikwazi ukukwenza oko. Isiphumo kukuba i-glucose ayikwazi ukungena kwiiseli ize iqokeleleke egazini. Ekugqibeleni, le meko iba yi-Type 2 Diabetes .
Kulapho ke kungena khona i-'IGF-1'. Uphando lufumanise ukuba abantu abanamanqanaba aphantsi e-'IGF-1' basengozini enkulu yokuhlaselwa ziimeko ezibizwa ngokuba yi-'Metabolic Syndrome'.
I-Metabolic Syndrome ayisosifo siqhelekileyo. Yindibaniselwano yeengxaki ezininzi zempilo, ezifana noxinzelelo lwegazi oluphezulu, i-cholesterol ephezulu, kunye namafutha esiswini. Xa zonke ezi zinto zidibana, umngcipheko wokuba nesifo sentliziyo kunye nesifo seswekile uyanda kakhulu.
Oku kuthetha ukuba ukuba amanqanaba akho e-IGF-1 aphantsi, kunokwenzeka ukuba ube nezinye iingxaki ezinokukhokelela kwisifo seswekile.
Ngaba i-IGF-1 inganyanga isifo seswekile?
Lo ngumbuzo abaphandi abazama ukuwuphendula kule mihla. Enye ingcebiso yoku liyeza elibizwa ngokuba yi-`mecasermin (Increlex).` Eli liyeza elenziwe ngokwenziwa, oko kukuthi, i-`IGF-1` hormone eyenziwe elebhu. Oogqirha basebenzisa eli yeza ukunyanga abantwana abancinci abangakhuli kakuhle.
Kodwa enye yeziphumo ebezingalindelekanga zale chiza kukwehla kwamanqanaba eswekile egazini, oko kukuthi, ukwenzeka kwesimo esibizwa ngokuba yi-'Hypoglycemia'. Oku kwatsala ingqalelo yabaphandi. Kwizifundo ezalandelayo, xa abantu abadala abanesifo seswekile sohlobo lwesibini banikwa le 'IGF-1', babona nokuba amanqanaba eswekile egazini labo ehla. Ukongeza, ukumelana kwabo ne-insulin kwaphucuka kakhulu.
Kodwa... oku kusesekwinqanaba lophando. Ngenxa yokuba i-IGF-1 yi-hormone eyenza izinto ezininzi emzimbeni, kusekho okuninzi ekufuneka kufundwe malunga nendlela esebenza ngayo. Okwangoku, i-IGF-1 ivunyiwe kuphela kwiingxaki zokukhula ebantwaneni. Ayikavunywa njengonyango lwesifo seswekile.
Masiqaphele nemiphumo emibi eyingozi.
I-'IGF-1` ayisiyonto yokudlala ngayo. Inokubangela iziphumo ebezingalindelekanga ezinzulu. Kubaluleke kakhulu ukuqaphela oku.
| Imiphumela | Ingcaciso elula |
|---|---|
| Ukudumba kwiRetina | I-retina lulwaleko olungaphakathi kweliso oluthumela oko sikubonayo engqondweni. Oku kudumba kunokubangela umonakalo omkhulu ekuboneni. |
| Intlungu enzima yemisipha kunye namalungu | Kusenokubakho iintlungu ezinganyamezelekiyo kwimisipha namalungu omzimba. |
| Ukukhubazeka kukaBell | Kulapho icala elinye lobuso liba buthathaka ngequbuliso lize liwe, lifane nokubetha. |
| Umngcipheko womhlaza | (Kubaluleke kakhulu) Kufunyaniswe ukuba i-IGF-1 inxulumene nophuhliso lomhlaza wamabele, wamathumbu amakhulu, wemiphunga, kunye noweprostate. |
Inyaniso malunga nezongezo
Le yingongoma ebalulekileyo kubantu abaninzi. Abanye abakhi bomzimba kunye nabadlali basebenzisa izongezo ze-IGF-1, nokuba zithengiswa ngaphandle kwekhawuntara okanye ngomyalelo kagqirha, ukuze bongeze imizimba yabo kwaye bonyuse amandla abo.
Kodwa khumbula, i-World Anti-Doping Agency (WADA) ithintele zonke iintlobo zehomoni i-IGF-1, kuquka nezongezo.
I-WADA ithi ne-'IGF-1' echazwe ngugqirha inokubangela umonakalo osisigxina kumalungu akho, kwisibindi, nakwintliziyo ukuba isetyenziswa gwenxa. Kuthekani ke ngezongezo ezithengiswa ngaphandle komthetho? Akukho namnye kuthi owaziyo ukuba ziqulethe ntoni na ngokwenene.
Abanye bawasebenzisa ukuze balwe nokwaluphala okanye bancede impilo jikelele. Liyinyaniso elokuba njengoko sikhula, imizimba yethu ivelisa i-IGF-1 encinci. Nangona kunjalo, akukho bungqina besayensi bokuba ukuthatha izongezo ze-IGF-1 kuya kukunceda uhlale uselula.
Le ngcinga ivela kuphando malunga neyeza lesifo seswekile i-metformin. Kwezo zifundo, iimpethu kunye neempuku zaziphila ixesha elide xa zinikwa i-metformin. Kodwa akukaziwa ukuba iza kubachaphazela njani abantu.
Ngoko ke, ukuba ucinga ngokuthatha isongezelelo se-`IGF-1`, nceda ungacingi nokucinga ngaso. Qiniseka ukuba uthetha nogqirha wakho ngaphambi kokuba wenze njalo. Ukujova izinto ezinjalo ezinamandla emzimbeni wakho ngaphandle kwengcebiso kagqirha kunokubangela ingozi engathethekiyo.
Umyalezo Wokuya Ekhaya
- I-'IGF-1' yihomoni yendalo efana ne-insulin ebalulekileyo ekukhuleni kwemizimba yethu.
- Amanqanaba aphantsi e-IGF-1 emzimbeni anxulunyaniswa nesifo iMetabolic Syndrome, enyusa umngcipheko wesifo seswekile nesifo sentliziyo.
- Nangona kukho uphando malunga nokusetyenziswa kwe-IGF-1 njengonyango lwesifo seswekile, ayikavunywa okwangoku.
- Le hormone inokubangela iziphumo ebezingalindelekanga ezinzulu ezifana nomonakalo wokubona, iintlungu zamalungu, kunye nomngcipheko womhlaza.
- Ukusetyenziswa kwezongezo ze-`IGF-1` kwimarike kuyingozi kakhulu. Zikwafakwe kuluhlu lwe-World Anti-Doping Agency.
- Soloko uqhagamshelana nogqirha wakho ngaphambi kokusebenzisa nasiphi na isongezelelo okanye amayeza.
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