Iyini i-VLDL (Very-Low-Density Lipoprotein) ku-cholesterol yakho? Ake sithole ukuthi iyini ngempela!

Cishe uke wezwa nge- cholesterol , akunjalo? Kungenzeka ukuthi uke walibona leli gama embikweni wakho wegazi. Akukho okufanele ukwesabe uma uzwa igama elithi cholesterol. Kodwa-ke, kunezinhlobo ezahlukene zalo, futhi kubalulekile ukwazi ngazo. Namuhla sizokhuluma ngelungu lomndeni we-cholesterol, futhi lelo yi -VLDL (Very-Low-Density Lipoprotein) . Leli gama lingase libe lisha kuwe, kodwa ungakhathazeki, ake silichaze kalula.

Iyini i-VLDL (Very-Low-Density Lipoprotein), mngane?

Kalula nje, i-VLDL uhlobo olukhethekile lwezinhlayiya ezenziwa yisibindi sethu bese zikhishwa egazini lethu. Lezi ziyingxenye yeqembu lamaprotheni abizwa ngokuthi ama-lipoprotein .

Cabanga ngakho, amafutha egazini lethu, njenge -cholesterol nama -triglyceride , awahambi egazini ngokwawo. Awancibiliki emanzini. Ngakho-ke, adinga imoto yokuthutha la mafutha aye ezingxenyeni ezahlukene zomzimba. Leyo moto ibizwa ngokuthi ama-lipoprotein. Kufana nebhasi!

Umsebenzi oyinhloko we-VLDL ukuthatha ama-triglycerides kanye ne-cholesterol ethile bese uyithutha uyiyise ezindaweni lapho idingeka khona emzimbeni. Ngale ndlela, i-VLDL isiza umzimba wethu ukuthola amandla, ukugcina amandla, kanye nokulawula umfutho wegazi. Ngakho-ke, zibaluleke kakhulu ekusebenzeni okuvamile komzimba wethu.

Kodwa-ke, nansi into okufanele uyikhumbule: Uma inani le-VLDL egazini liba phezulu kakhulu , kungaba yingozi. Uma lokho kwenzeka, ingozi yokuthola isifo senhliziyo iyanda.

Yini engaphakathi kwalezi zinhlayiya ze-VLDL?

Inhlayiya ye-VLDL yakhiwa kakhulu uhlobo lwamafutha olubizwa ngokuthi ama-triglycerides . Iphinde iqukethe i-cholesterol , ama-fatty acid, kanye nohlobo olukhethekile lweprotheyini olubizwa ngokuthi i-apolipoprotein B (apoB) . Ucwaningo luthole ukuthi amazinga aphezulu ale apoB egazini ahlotshaniswa nengozi eyengeziwe yesifo senhliziyo.

Eqinisweni, wonke ama-lipoprotein akhiwe ngamafutha namaprotheni. Kodwa-ke, inani nezinhlobo zala mafutha namaprotheni ziyahlukahluka kusuka kuma-lipoprotein ahlukahlukene kuya kwenye. Ngenxa yokuthi ama-VLDL aphezulu kakhulu kuma -triglycerides , odokotela ngezinye izikhathi bawabiza ngokuthi "ama-lipoprotein acebile ngama-triglyceride."

Ingabe i-VLDL ne-VLDL cholesterol zizinto ezihlukene?

Lokhu kungase kubonakale kudida kancane, kodwa kulula ukukuqonda. Ngokuvamile, amagama athi "VLDL" kanye "ne-VLDL cholesterol" asetshenziswa ngokushintshana. Kodwa-ke, kunomehluko omncane phakathi kwalawa amabili okubalulekile ukuwazi.

• I-VLDL ibhekisela ku-lipoprotein particle esikhulume ngayo ekuqaleni. Okusho ukuthi, "imoto" noma "ibhasi" elenziwa yisibindi futhi lithwala amafutha namaprotheni egazini.
• I-cholesterol ye-VLDL ibhekisela kubagibeli be-cholesterol ebhasini le-VLDL. Okusho ukuthi, inani le-cholesterol elithuthwa kulo lonke igazi yi-VLDL particle.

Ezinye izinhlobo zama-lipoprotein, njenge -LDL (Low-Density Lipoproteins) kanye ne-HDL (High-Density Lipoproteins) , zifana nalezi ezinye izinhlobo ze-cholesterol. Ngayinye inenani elihlukile kanye nezinhlobo zamafutha namaprotheni. Yingakho sikhuluma futhi nge-LDL cholesterol kanye ne-HDL cholesterol.

Ngakho-ke ingabe i-VLDL uhlobo lwe-cholesterol "embi"?

Yebo, ngamafuphi, uma inani le-cholesterol ye-VLDL egazini liphakeme kunokudingekile, kungathiwa "libi". Umzimba wethu udinga inani elithile le-VLDL ngokwezidingo zawo. Kodwa-ke, uma izinga le-VLDL likhuphuka, kwandisa ingozi ye-atherosclerosis , okungukuthi, ukwakheka kwama-fatty deposits (i-plaque) ngaphakathi kwemithambo yegazi (imithambo yegazi). Lesi yimbangela eyinhloko yezifo eziningi zenhliziyo.

I-VLDL inegalelo kanjani ekukhuleni kwe-atherosclerosis?

Uma isibindi sethu sikhiqiza i-VLDL eningi kunalokho umzimba wethu okudingayo, umzimba uyayigaya (uyayibhidliza) i-VLDL eyengeziwe. Ngale ndlela, i-VLDL iqala iguqulwe ibe yi -IDL (Intermediate-Density Lipoproteins) bese kuba yi-LDL (Low-Density Lipoproteins) . Lawa ma-IDL kanye ne-LDL yizinhlobo zama -lipoprotein ezidingwa umzimba.

Kodwa, inkinga iwukuthi, uma le LDL iba ngaphezu kwalokho umzimba okudingayo, inganqwabelana. Uma kune -LDL eningi egazini, ingabhajwa odongeni lwemithambo yegazi, lapho kuqala khona ukwakheka kwama-fatty deposits (i-plaque) . Njengoba la ma-fatty deposits ekhula kancane kancane, anciphisa imithambo yegazi futhi avimbele ukuhamba kwegazi.

Ucwaningo luthole ukuthi ukwanda kwamazinga e-VLDL kanye nokwanda kwamazinga e-LDL kuyingozi kakhulu kunokwanda kokubili.

Akukhona lokho kuphela, lapho i-VLDL iphuka futhi kwakheka i-LDL, ezinye " izinhlayiya ezisele" zishiywa egazini. Lezi zinhlayiya ezisele nazo ziqukethe i-cholesterol eningi. Ngenxa yokuthi zincane ngobukhulu, zingabhajwa kalula ezindongeni zemithambo yegazi futhi zibangele i-atherosclerosis (Kusheshisa inqubo ye-atherosclerosis.

I-atherosclerosis iyisimo esiyingozi ngoba inciphisa imithambo yakho yegazi, yandisa ingozi yakho yokuthola izifo ezahlukahlukene zenhliziyo nemithambo yegazi. Nazi izibonelo ezimbalwa:

• Isifo semithambo yenhliziyo ( izifo zemithambo yegazi ehambisa igazi enhliziyweni)
• Isifo semithambo yegazi ( izifo ezisemithanjeni yegazi ezihambisa igazi ebuchosheni, ezingaholela ezimweni ezifana nesifo sohlangothi)
• Isifo semithambo yegazi engaphandle ( izifo zemithambo yegazi ezihlinzeka ngegazi ezingalweni nasemilenzeni)
• I-Aortic aneurysm (ubuthakathaka nokukhukhumala kwe-aorta, umthambo wegazi oyinhloko womzimba)

Yikuphi okubi kakhulu, i-LDL noma i-VLDL?

Eqinisweni, kokubili i-cholesterol ye-LDL kanye ne-cholesterol ye-VLDL kunegalelo ekwakhekeni kwama-fatty deposits (i-plaque) emithanjeni yethu yemithambo. Ngakho-ke, kunzima ukusho ukuthi enye "imbi kakhulu" kunenye. Zombili zifana ne-atherogenic, okusho ukuthi zinegalelo enqubweni yama-fatty deposits emithanjeni. Ngakho-ke kubalulekile ukuqaphela kokubili.

Ilinganiswa kanjani i-cholesterol ye-VLDL?

Odokotela balinganisa amazinga akho e-VLDL cholesterol ngokuhlolwa kwegazi okubizwa ngokuthi i-lipid panel . Lokhu ukuhlolwa kwegazi okuvamile kakhulu.

Leli phaneli le-lipid likhombisa izinga le-cholesterol eliphelele egazini lakho. Akukhona lokho kuphela, kodwa libonisa namazinga ezinhlobo ezahlukene ze-cholesterol ebizwa ngokuthi i-HDL (i-cholesterol enhle), i-LDL (i-cholesterol embi), kanye ne-VLDL ngokwehlukana. Futhi, lokhu kuhlolwa kungakutshela izinga le -triglycerides egazini lakho. Khumbula, sithe i-VLDL iqukethe ama-triglycerides amaningi.

Ngokuvamile, ama-lab awalinganisi amazinga akho e-VLDL ngqo. Kunalokho, asebenzisa amazinga akho e-triglyceride ukubala amazinga akho e-VLDL ngefomula yezibalo. Ngokuvamile, amazinga akho e-triglyceride aphindwe kahlanu amazinga akho e-VLDL.

Kodwa-ke, uma unesifo esibi esibizwa ngokuthi i-hypertriglyceridemia , okuyilapho amazinga akho e-triglyceride ephezulu kakhulu, leso sibalo singase singabi neqiniso. Kuleso simo, udokotela wakho angasebenzisa indlela ehlukile ukulinganisa amazinga akho e-VLDL.

Iyini izinga elijwayelekile le-cholesterol ye-VLDL?

Izinga elijwayelekile, noma elinempilo, le-VLDL lingaphansi kwama-milligram angu-30 nge-deciliter yegazi ( < 30 mg/dL ). Uma izinga lakho le-cholesterol le-VLDL lingu- 30 mg/dL noma ngaphezulu , libhekwa njengeliphezulu.

Kwenzekani uma i-cholesterol ye-VLDL iphakanyisiwe?

Into eyinhloko ukuthi amazinga aphezulu e-VLDL cholesterol andisa ingozi yesifo senhliziyo .

Kodwa-ke, ngenxa yokuthi amazinga e-VLDL abalwa kusetshenziswa ifomula yezibalo kunokuba alinganiswe ngqo, futhi ngenxa yokuthi i-VLDL akuyona into eyinhloko odokotela abayisebenzisayo lapho bekwelapha, udokotela wakho angase angakhulumi nawe ngqo ngezinga lakho le-VLDL. Esikhundleni salokho, uzogxila kakhulu kwamanye amanani, njengezinga lakho le-LDL kanye nama-triglycerides , ngoba lawo ngamanani ahloselwe ukwelashwa.

Abantu abaningi abanamazinga aphezulu e-VLDL cholesterol bangase babe nesinye noma ngaphezulu kwalezi zimo ezilandelayo ngesikhathi esisodwa:

• Amazinga e-triglyceride akhuphukile (i-Hypertriglyceridemia)
• Amazinga e-cholesterol e-LDL akhuphukile
• Ukwanda kwezinga le-cholesterol ephelele (i-Hyperlipidemia)

Izindaba ezinhle ukuthi, kunezinto eziningana ongazenza ukuze unciphise lezi zinhlobo zamafutha (ama-lipid) egazini lakho:

• Ukulandela ukudla okunempilo kwenhliziyo , njengokudla kwaseMedithera , okugcizelela imifino, izithelo, ubhontshisi, okusanhlamvu okuphelele, inhlanzi, namafutha anempilo njengamafutha omnqumo.
• Vivinya umzimba njalo . Kodwa-ke, kubaluleke kakhulu ukukhuluma nodokotela wakho futhi uthole iseluleko ngaphambi kokuqala uhlelo olusha lokuzivocavoca.
• Gcina isisindo esinempilo esifanelana nobude bakho nohlobo lomzimba wakho.
• Uma udokotela wakho ekuncoma, thatha imithi yokwehlisa i-cholesterol efana nama-statin .

Kwezinye izimo, ungase ube nesimo sezokwelapha esingaphansi esingabangela ukwanda kwama-triglycerides akho, okungabangela futhi ukwanda kwamazinga akho e-cholesterol e-VLDL. Futhi, eminye imithi oyithathayo ingabangela ukwanda kwalokhu kokubili. Ngakho-ke, kubalulekile ukukhuluma ngokukhululekile nodokotela wakho ngalokho okubangela ukwanda kwamazinga akho e-cholesterol e-VLDL nokuthi yini ongayenza ukuze uwaxazulule.

Empilweni yakho yansuku zonke, cishe awucabangi kakhulu ngala ma-lipoprotein ahambahamba egazini lakho. Kodwa uma udokotela ekutshela ukuthi amazinga akho e-cholesterol aphezulu, ungase uqale ukucabanga ngalezi zinhlayiya nokuthi zithinta kanjani impilo yakho.

Ekugcineni, into okufanele uyikhumbule...

Into ebaluleke kakhulu ukungesabi uma uthola ukuthi amazinga akho e-cholesterol aphezulu. Lesi yisimo esingalawulwa ngokushintsha indlela yokuphila kanye, uma kudingeka, ngemithi.

Khuluma nodokotela wakho ngokuthi izinga lakho le-VLDL lisho ukuthini kuwe nokuthi yini ongayenza ukuze ulithuthukise. Uzokunikeza iseluleko esingcono kakhulu. Ukuze uhlale uphilile, kungcono ukuqaphela lezi zinto bese ulandela iseluleko sikadokotela wakho!

I- Cholesterol, i-VLDL, ama-Triglycerides, Isifo Senhliziyo, I-Lipid Panel, I-Atherosclerosis, Impilo