Uma wena noma othandekayo wakho ninikezwa umuthi omusha wokwelapha umdlavuza, kuvamile ukuzizwa ninovalo futhi nifuna ukwazi. Ikakhulukazi uma uzwa igama elifana ne-Acalabrutinib, ungase uzibuze, "Luhlobo luni lomuthi? Kwenzekani kuwo ?" Ungakhathazeki. Yilokho kanye esikhuluma ngakho kulesi sihloko. Sizokhuluma ngalo muthi ngendlela elula ongayiqonda.
Uhlobo luni lomuthi i-Acalabrutinib?
Kalula nje, i-Acalabrutinib iwumuthi osetshenziselwa ukwelapha izinhlobo ezithile zomdlavuza, ikakhulukazi i-leukemia kanye ne-lymphoma. Ezweni lakithi, lo muthi utholakala ngaphansi kwegama lomkhiqizo i-CALQUENCE.
Lokhu akufani nemithi yomdlavuza yendabuko. Lokhu kusebenza "njengokwelashwa okuqondiwe." Okusho ukuthi, lo muthi uhlose ngqo iphrotheni ethile esiza amangqamuzana omdlavuza ukuba akhule futhi asakazeke. Uma le phrotheni iyeka ukusebenza, ikhono lamangqamuzana omdlavuza lokukhula liyancishiswa, noma afe ngokuphelele. Ngale ndlela, lo muthi usiza ukulawula umdlavuza.
Izinto okufanele uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokuqala i-acalabrutinib, kubaluleke kakhulu ukunikeza udokotela wakho incazelo ephelele yempilo yakho. Qiniseka ukuthi utshela udokotela wakho uma unezinye zezimo ezilandelayo:
- Uma unesifo sokopha (isib., izinkinga zokujiya kwegazi).
- Uma usanda kuhlinzwa noma uhlela ukukwenza esikhathini esizayo.
- Uma unesifo senhliziyo , umfutho wegazi ophakeme , noma ukushaya kwenhliziyo okungajwayelekile.
- Uma kukhona ukutheleleka okukhona.
- Uma unesifo sesibindi .
- Uma uthatha imithi yokunciphisa igazi ukuze uvimbele noma welaphe amahlule egazi.
- Uma une -allergies ku-acalabrutinib noma kunoma yimuphi omunye umuthi, ukudla, noma udayi.
- Uma ukhulelwe , uzama ukukhulelwa , noma uncelisa .
Ngokunikeza udokotela wakho lolu lwazi ngokunembile, uzokwazi ukukwelapha ngokuphephile nangendlela ephumelelayo.
Ngingawusebenzisa kanjani lo muthi?
Kubaluleke kakhulu ukulandela imiyalelo eqondile yokusebenzisa lo muthi.
- Gwinya leli kapsuli liphelele ngengilazi yamanzi .
- Ungalokothi uphule, uchoboze, noma uhlafune leli kapsuli. Ligwinye lonke.
- Uma uhlangabezana nemiphumela emibi, udokotela wakho angakucela ukuthi ushintshe umthamo womuthi noma uyeke ukuwuthatha isikhashana. Ungayeki ukuthatha umuthi noma ushintshe umthamo nganoma yisiphi isizathu ngaphandle kweseluleko sikadokotela wakho.
- Ungawuthathi lo muthi kanye nejusi lamagilebhisi.
- Uma uthatha imithi yesisu (ama-antacid noma ama-H2-blockers), yithathe amahora ama-2 ngaphambi noma ngemva kokuthatha i-Acalabrutinib.
Kuthiwani uma ngengozi ngithatha umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe umuthi omningi kunalokho okucabangayo, ungesabi futhi ngokushesha shayela i-National Poisons Information Centre e-Colombo National Hospital . Ngaphandle kwalokho, iya e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Kuthiwani uma ngiphuthelwa umthamo wemithi?
Uma uphuthelwe umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekwephuzile amahora angaphezu kwama-3 , yeqa umthamo ophuthelwe. Thatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungathathi imithamo emibili ngesikhathi esisodwa.
Ezinye izinto ezingase zihlangane nalo muthi (Ukusebenzisana)
I-Acalabrutinib ingasebenzisana neminye imithi, amavithamini, noma imikhiqizo yamakhambi okungenzeka ukuthi uyayithatha. Ngakho-ke tshela udokotela wakho ngayo yonke imithi, amavithamini, kanye nezithasiselo ozithathayo. Ngezansi kunezinto ezimbalwa nje ezingadala izinkinga.
| Yini engabangela izinkinga? | Incazelo nezibonelo |
|---|---|
| Imithi yokwehlisa i-asidi yesisu | Imithi efana ne-Cimetidine, i-Famotidine, i-Omeprazole, i-Lansoprazole. Ama-antacid. |
| Amanye ama-antibiotic | Imithi efana neClarithromycin neRifampin. |
| Imithi yokulwa nesikhunta | Imithi efana ne-Ketoconazole, i-Itraconazole, ne-Fluconazole. |
| Imithi yokwelapha isithuthwane | Izidakamizwa ezifana neCarbamazepine nePhenytoin. |
| Imikhiqizo yezitshalo | Imikhiqizo efana ne-St. John's Wort. |
| Ukudla neziphuzo | Ijusi le-grapefruit. |
Imiphumela emibi engaba khona lapho uthatha umuthi
Njenganoma yimuphi umuthi, i-Acalabrutinib ingabangela imiphumela emibi. Eminye mincane, kanti eminye idinga ukunakekelwa okusheshayo.
| Umphumela ongemuhle | Izici |
|---|---|
| Izinto okufanele uzibike kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo. |
| Ukopha okungavamile | Indle emnyama noma enegazi, ukuhlanza okufana nekhofi elicwecwe, umchamo obomvu noma onsundu omnyama, amabala amancane abomvu noma onsomi esikhumbeni, ukuminyana okungavamile. |
| Izinguquko ekushayeni kwenhliziyo | Ukuzizwa sengathi inhliziyo yakho ishaya ngokushesha noma ngokungajwayelekile, isiyezi, ubuhlungu besifuba, nobunzima bokuphefumula. |
| Izifo | Umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, amanxeba angapholi, ubuhlungu lapho uchama. |
| I-anemia | Ukuzizwa ukhathele noma ubuthakathaka ngendlela engajwayelekile, isiyezi, ikhanda elibuhlungu, nobunzima bokuphefumula. |
| Tshela udokotela wakho uma kuqhubeka noma kuyakhathaza. | |
| Ezinye izifo ezivamile | Uhudo, ikhanda elibuhlungu, ukukhathala, ubuhlungu bemisipha, isicanucanu. |
Izinto okufanele uziqaphele kakhulu ngesikhathi sokwelashwa
Impilo yamazinyo
Ngaphambi kokuthi uqale ukuthatha lo muthi, kuwumqondo omuhle ukubona udokotela wamazinyo bese uhlolwa amazinyo akho. Udokotela wakho angase akucebise ukuthi ugweme ukuhlinzwa okukhulu kwamazinyo ngesikhathi sokwelashwa. Futhi, gcina amazinyo akho ehlanzekile.
Ukuvikelwa kwelanga
Abanye abantu bangase babe nengozi eyengeziwe kancane yokuthola ezinye izinhlobo zomdlavuza (ikakhulukazi umdlavuza wesikhumba) ngenkathi bethatha lo muthi. Ngakho-ke, gqoka izingubo ezimboza kahle futhi usebenzise isivikelo selanga uma uphuma elangeni.
Ukukhulelwa nokuncelisa
Lokhu kubaluleke kakhulu: Gwema ukukhulelwa ngenkathi uthatha lo muthi futhi okungenani isonto elilodwa ngemuva kokuyeka umuthi. Lo muthi ungabangela umonakalo omkhulu enganeni engakazalwa. Futhi, gwema ukuncelisa ngenkathi uthatha lo muthi kanye namasonto amabili ngemuva kokuyeka umuthi.
Umlayezo Wokuya Nawe Ekhaya
- Gwinya njalo i-capsule ye-acalabrutinib yonke. Ungayephuli, ungayichobozi, noma uyihlafune.
- Tshela udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nezithasiselo ozithathayo.
- Gwema ukuphuza ijusi le-grapefruit kanye ne-grapefruit ngenkathi uthatha lo muthi.
- Uma ubona ukopha okungajwayelekile, ukuklwebheka, noma izimpawu zokutheleleka (umkhuhlane, ukubanda), tshela udokotela wakho ngokushesha.
- Gwema ukuthatha lo muthi ngesikhathi sokukhulelwa noma ngesikhathi uncelisa. Khuluma nodokotela wakho ngalokhu.
- Ungalokothi uyeke ukuthatha imithi noma ushintshe umthamo ngaphandle kweseluleko sikadokotela wakho.
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Ama-capsule e-Acalabrutinib (Calquence) ayisidakamizwa esibiza kakhulu esisetshenziselwa ukwelapha yisiphi isifo?
Leli akulona iphilisi elivamile! Leli yiphilisi lomdlavuza elisebenza kahle kakhulu futhi elinamandla (i-Bruton Tyrosine Kinase - BTK Inhibitor) eliqondiswe kumdlavuza elisanda kutholakala ezigulini ezinomdlavuza njenge-'Mantle Cell Lymphoma (MCL)' kanye ne-'Chronic Lymphocytic Leukemia (CLL), okuyizinhlobo zomdlavuza wegazi ezinamandla kakhulu nezimbi kakhulu ezikhula emangqamuzaneni amhlophe egazi (amaseli e-B), kanye nalabo abangazange bathole olunye ukwelashwa!
💬 Uma amangqamuzana omdlavuza wegazi ekhula ngendlela engalawuleki, ukuthatha la maphilisi (i-Calquence) kuwubhubhisa kanjani umdlavuza?
Ukuze amangqamuzana omdlavuza wegazi asakazeke futhi asinde, i-enzyme ekhethekile ebizwa ngokuthi 'BTK' kumele ithumele umlayezo/isignali! Lapho nje lo muthi ungena emzimbeni, uya emshinini 'we-BTK' ophakela/osakaza umdlavuza bese uwuvimba ngokuphelele futhi unomphela (Ubopha ngokungenakulungiseka) bese uwukhiya. Lapho nje isignali ilahlekile, wonke lawo maseli omdlavuza ayayeka ukusabalala (Avimbela ukwanda kwamangqamuzana e-B), umdlavuza uyafa bese isiguli siyalulama.
💬 Yiziphi izingozi ezibulalayo kanye nemiphumela emibi okufanele abantu abasebenzisa lo muthi womdlavuza (i-Acalabrutinib) baziqaphele?
Ingozi enkulu yalo muthi ukuthi uyalimaza uhlelo lokujiya kwegazi, ngakho-ke ngaphandle kwesizathu, isiguli singaba 'nokuphuma kwegazi okubulalayo' ebuchosheni noma emathunjini bese sifa ngokuzumayo (yingakho imithi yokunciphisa igazi/i-Warfarin ivinjelwe)! Enye ingozi enkulu ukuthi iwenza buthaka ngokuphelele amasosha omzimba, ngakho-ke ngisho nokutheleleka okuncane kwamagciwane kungabangela isiguli ukuba singene kwi-coma (Severe Infections). Kungabangela nesifo esibi lapho inhliziyo ishaya khona njengokuhlanya (Atrial Fibrillation).
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho