Ingabe izitho zakho zomzimba nobuso bakho kushintsha kancane kancane isimo futhi kuba kukhulu? Ake sixoxe nge-Acromegaly.

Wake wazizwa sengathi usayizi wezicathulo zakho uyakhula, noma ukuthi indandatho owawuyigqoka manje isinamathele emunweni wakho? Mhlawumbe isimo sobuso bakho sibukeka sihlukile kancane uma ubheka izithombe ezindala? Eziningi zalezi zinto zenzeka ngokuhamba kwesikhathi, ngezinye izikhathi iminyaka, ngakho asizinaki kakhulu. Kodwa lokhu kungaba uphawu lwesifo esingavamile esibizwa ngokuthi i-Acromegaly . Ungakhathazeki, sizoxoxa ngakho konke ngamagama alula.

Kalula nje, iyini i-Acromegaly?

I-Acromegaly yisimo esibangelwa ukuthi imizimba yethu ikhiqiza i-hormone yokukhula eningi kakhulu, noma i-Growth Hormone (GH) . Le hormone isisiza sikhule sisebancane. Kodwa-ke, uma le hormone iqhubeka nokukhishwa ngemva kokuba sesiqedile ukukhula, okungukuthi, ngemva kokuba sesikhulile, ezinye izingxenye zomzimba wethu, ikakhulukazi amathambo ezingalo, imilenze, nobuso, ziqala ukukhula ngendlela engavamile.

Lesi simo sivame ukubonakala kakhulu kubantu abaseminyakeni ephakathi. Kodwa lokhu akusho ukuthi asibonakali kubantu abasebasha. Uma i-hormone yokukhula ikhula ngale ndlela besebancane, lesi simo sibizwa ngokuthi i-gigantism. Bese bekhula babe bade ngendlela engavamile.

I-Acromegaly akuyona isimo sokuphakama okuphezulu, kodwa kunalokho ushintsho esimweni samathambo asevele ekhulile. Ngenxa yokuthi lezi zinguquko zenzeka kancane, kungenzeka zingabonwa njengesimo sezokwelapha iminyaka eminingi.

Kungani i-acromegaly ikhula? Ziyini izimbangela?

Isizathu esiyinhloko salokhu yindlala encane elingana nobhontshisi phansi kobuchopho bethu. Siyibiza ngokuthi yi -Pituitary Gland . Imbangela evame kakhulu ye-Acromegaly yithumba elingenalo umdlavuza (elingenobungozi) kule ndlala. Lesi simila sibizwa ngokuthi i-Pituitary Adenoma . Lesi simila sivuselela indlala ye-pituitary futhi sikhiqize i-hormone yokukhula (GH) eningi kakhulu.

Le hormone ye-GH eningi iqoqana egazini lethu futhi itshele isibindi ukuthi sikhiqize enye i-hormone ebizwa ngokuthi i-IGF-1 (Insulin-like Growth Factor-1) . Leyo hormone ye-IGF-1 yiyona ebangela ukuba amathambo ethu nezinye izitho zomzimba zikhule ngendlela engajwayelekile. Iphinde ithinte indlela umzimba wethu olawula ngayo ushukela namafutha, okwandisa ingozi yokuthola ezinye izifo.

Akuvamile kakhulu, lesi simo singabangelwa nayizimila ezikhula kwezinye izingxenye zepancreas, isibindi, noma ubuchopho. Ucwaningo luthole ukuthi ezinye izici zofuzo nazo zingadlala indima.

Ziyini izimpawu ze-acromegaly?

Lezi zimpawu zivame ukubonakala kancane kancane, ngakho-ke kungathatha isikhathi ukuthi uqaphele umehluko.

Ungasithola kanjani lesi sifo?

Kubalulekile ukuqaphela lesi simo ngokushesha okukhulu. Uma ubona udokotela ngenxa yalezi zimpawu, uzokubuza imibuzo efana nalokhu:

• Yiziphi izinguquko ozibonayo?
• Uqale nini ukuqaphela lezi zinguquko?
• Uzizwa kanjani manje?

Ngemuva kwalokho, kwenziwa izivivinyo eziningana ukuqinisekisa ukuxilongwa.

Ukuhlolwa okuyinhloko

• Ukuhlolwa kwegazi: Ukuhlolwa kwegazi kwenziwa ukuze kubonakale ukuthi amazinga akho e-IGF-1 aphakeme yini ngokweminyaka yakho.
• Ukuhlolwa Kokubekezelela I-glucose: Lapha, unikezwa isiphuzo esinoshukela bese amazinga kashukela egazini lakho kanye nama-hormone e-GH alinganiswa amahora amabili. Ngokuvamile, amazinga e-GH kufanele ehle ngemva kokuphuza ushukela. Uma engakwenzi lokho, futhi ehlala ephezulu, kuwuphawu lwe-acromegaly.

Ezinye izivivinyo

• I-MRI noma i-CT scan: Lezi skeni zisiza ekutholeni isimila se-pituitary.
• Ukuhlolwa kwe-X-ray: Hlola ukuthi amathambo ayaqina yini.
• I-Echocardiogram: Ukuhlolwa kwenhliziyo nge-ultrasound ukuze kubonakale ukuthi inhliziyo ithintekile yini.
• I-Colonoscopy: Hlola impilo ye-colon.
• Ucwaningo Lokulala: Bheka ukuthi une-Sleep Apnea yini.

Yiziphi izindlela zokwelapha?

Udokotela wakho uzonquma uhlelo lokwelashwa olufanele kakhulu kuwe ngokusekelwe eminyakeni yakho, isimo sempilo, kanye nobunzima besimo sakho. Kunezindlela ezintathu zokwelapha eziyinhloko.

1. Ukuhlinzwa:

Ngokuvamile, ukwelashwa kokuqala ukuhlinzwa ukuze kususwe isimila se-pituitary. Lokhu kubaluleke kakhulu uma isimila sicindezela imizwa ethinta umbono. Udokotela ohlinzayo ususa isimila ngokusikwa okuncane ngekhala noma ngaphakathi kodebe olungaphezulu. Izimpawu zingase ziqale ukuthuthuka zingakapheli izinsuku ezimbalwa ngemva kokuhlinzwa.

2. Imithi:

Uma kukhona izingcezu ezisele zesimila ngemva kokuhlinzwa noma uma udinga usizo olwengeziwe lokulawula amazinga akho ama-hormone, udokotela wakho uzokunikeza imithi. Le mithi yehlisa amazinga akho e-GH noma ivimbele imiphumela yayo emzimbeni.

• Ama-analogue e-Somatostatin (isb. i-lanreotide, i-octreotide)
• Ama-addict hormone receptor antagonists (isb. i-pegvisomant)
• Ama-agonist e-dopamine (isb. i-cabergoline)

3. Ukwelashwa Ngemisebe:

Uma kusenezingxenye zesimila ezisele ngemva kokuhlinzwa kanye nemithi, noma uma amazinga e-GH edinga ukuncishiswa kakhulu, kusetshenziswa ukwelashwa ngemisebe. Lokhu kuvimbela isimila ukuthi singakhuli futhi kunciphisa ukukhiqizwa kwe-GH. Amasu esimanje afana nokuhlinzwa ngemisebe ye-stereotactic angaletha imithamo ephezulu yemisebe esimila ngaphandle kokulimaza izicubu ezinempilo.

Izinkinga ezingase zenzeke uma zingelashwa

I-Acromegaly ingabangela izinkinga ezinkulu zempilo uma ingelashwa kahle, ngakho ungasinaki lesi simo.

• Isifo senhliziyo
• Isifo sikashukela
• Umfutho wegazi ophakeme
• Isifo Samathambo (i-Osteoarthritis)
• I-Carpal Tunnel Syndrome
• Ukuphelelwa Yisikhathi Kokulala
• Ukulahlekelwa umbono
• Ingozi eyengeziwe yomdlavuza wamathumbu amakhulu
• Ukucindezelwa kwemizwa yomgogodla

Lesi simo singaba yingozi empilweni uma singelashwa, ngakho-ke kubalulekile ukufuna iseluleko sezokwelapha ngokushesha uma unezimpawu.