Wake waphawula ukuthi othile emndenini wakho, mhlawumbe umama wakho othandekayo, ubaba, ugogo noma umkhulu, ukhohlwa izinto kancane kancane? Ekuqaleni, izinto ezincane, kodwa lapho bekhohlwa izinto ezibalulekile, sonke siyasaba kancane. Lesi simo yilokho esivame ukukubiza ngokuthi i-Alzheimer's Disease. Kuyisimo esiyinkimbinkimbi kakhulu nesicindezelayo. Kodwa izindaba ezinhle ukuthi odokotela nososayensi emhlabeni wonke basebenza imini nobusuku ukuthola ikhambi lalesi sifo. Namuhla, ake sixoxe ngethemba elisha esilinikezwe lolu cwaningo.
Kungani ucwaningo lwe-Alzheimer lubaluleke kangaka?
Kalula nje, isifo i-Alzheimer's yisifo esibhubhisa kancane kancane amangqamuzana obuchopho, okuholela ekukhumbuleni, ekucabangeni, kanye nekhono lokwenza imisebenzi yansuku zonke. Lokhu kubangelwa ukunqwabelana kwamaprotheni angajwayelekile abizwa ngokuthi ama-amyloid beta plaques ebuchosheni. Cabanga ngakho njengokunqwabelana kwamaprotheni nezinsalela ezindleleni ezithwala ulwazi phakathi kwamangqamuzana ezinzwa ebuchosheni bethu, okuvimba lezo zindlela. Yilokho okwenzeka kula maprotheni.
Kuze kube manje, akukho khambi elitholakale lalesi sifo. Yingakho ucwaningo luyithemba lethu elikhulu . Izinkampani zemithi ezihamba phambili emhlabeni, izikhungo ezifana nohulumeni waseMelika, kanye nezinhlangano ezifana ne-Alzheimer's Association zitshale imali eningi kulolu cwaningo. Zinezinhloso ezintathu eziyinhloko:
1. Ukuthola izindlela zokwelapha ezinciphisa izimpawu.
2. Ukuthola izindlela zokuvimbela lesi sifo ukuthi singabi khona.
3. Ukunikeza ukwelashwa okuphelele kulabo asebevele benesifo.
Amaphuzu abalulekile okugxila ocwaningweni
Abacwaningi babheka lesi sifo ngezindlela eziningi ezahlukene. Njengokuxazulula iphazili enkulu, bahlanganisa ulwazi oluvela kuzo zonke izinhlangothi ukuze bakhe isithombe esiphelele.
Izinto ezandisa ingozi yokuthola lesi sifo
Abanye abantu banamathuba amaningi okuthola isifo i-Alzheimer's kunabanye. Abacwaningi bafunda kabanzi ngalezi zici eziyingozi ngoba ukuthola ukuthi yini ezibangela kungasiza ekuvimbeleni lesi sifo.
| Isici Sengozi | Incazelo elula |
|---|---|
| Ukuguga | Lesi yisona sici esiyinhloko sengozi. Ingozi iyanda kancane kancane ngemva kweminyaka engu-65. Kodwa-ke, akuwona wonke umuntu okhula eba nalesi sifo. |
| Umlando womndeni kanye nezakhi zofuzo | Uma umama wakho, ubaba, noma umfowenu noma umfowenu babenalesi sifo, nawe ungase ube sengozini. Izakhi zofuzo ezithile ziyasithinta. |
| Ukulimala okukhulu ekhanda | Ukulimala okukhulu ekhanda (ikakhulukazi okubangela ukulahlekelwa ingqondo) ngesikhathi sobusha noma nganoma yisiphi isikhathi kungandisa ingozi esikhathini esizayo. |
| Izinga lemfundo eliphansi | Imfundo kanye nomsebenzi ojwayelekile odinga ubuchopho obuningi kudala inethiwekhi eqinile yokuxhumana phakathi kwamangqamuzana obuchopho. Lokhu kuholele ekutholakaleni kokuthi abantu abanemfundo encane bangase babe sengozini enkulu kancane. |
Ukwelashwa okusha okuvunyiwe
Lena yindawo ethembisayo kakhulu. Muva nje, i-US Food and Drug Administration (FDA) ivumile imithi emibili ehlose futhi isuse ama-amyloid beta plaque ebuchosheni, esikhulume ngawo ngaphambili, okuyimbangela eyinhloko yesifo i-Alzheimer's.
1. I-Aducanumab-avwa (i-Aduhelm)
2. I-Lecanemab-irmb (Leqembi)
Esikhundleni sokwelapha lesi sifo ngokuphelele, le mithi isiza ekunciphiseni ukuqhubeka kwalesi sifo futhi isuse amaprotheni ayingozi ebuchosheni. Lokhu kubhekwa njengesinyathelo esikhulu sokuqhubekela phambili emkhakheni wokwelashwa kwe-Alzheimer's.
Lo muthi kungenzeka ukuthi awukatholakali eSri Lanka, kodwa ngemiphumela yocwaningo olufana nalolu, singathemba ukuthi kuzovela ukwelashwa okuphumelelayo maduze nje.
Izinto ezisiza ekuvikeleni ezifweni
Ucwaningo alugcini nje ngokubheka izinto eziyingozi, kodwa futhi 'nezici zokuzivikela' ezisiza ekuvikeleni lesi sifo.
- Ukusetshenziswa kwama-NSAID: Imithi elwa nokuvuvukala engeyona eye-steroidal (ama-NSAID) imithi esiyisebenzisayo ukunciphisa ubuhlungu nokuvuvukala, njenge-ibuprofen ne-diclofenac. Izifundo zibonise ukuxhumana phakathi kokusetshenziswa kwayo kanye nengozi encishisiwe ye-Alzheimer's. Kodwa lokhu kubaluleke kakhulu: ngaphandle kwesizathuUngasebenzisi lolu hlobo lomuthi ukuvimbela i-Alzheimer's ngaphandle kweseluleko sikadokotela. Kungabangela eminye imiphumela emibi.
- Ama-Antioxidants: Lezi yizinto ezilwa nama-free radicals, alimaza amangqamuzana emizimbeni yethu. Atholakala ngobuningi ezithelweni, emifinweni, kanye nasemajikijolweni amnyama. Yingakho ukudla okulinganiselayo kubaluleke kangaka.
- Ukugcina ubuchopho busebenza: Ukuthola imfundo ephakeme, ukusebenza emsebenzini oyinkimbinkimbi, ukufunda okuthile okusha (ulimi, insimbi yomculo), ukuxazulula amaphazili, njll. kugcina ubuchopho busebenza. Lokhu kwandisa 'ukugcinwa kwengqondo' kobuchopho futhi kungalibazisa ukuqala kwezimpawu.
Singazifaka kanjani lezi zinto ekuphileni kwethu?
Kungakhathaliseki ukuthi ucwaningo lwenziwa kuphi emhlabeni, ulwazi olulethayo lungasetshenziswa ezimpilweni zethu. Uma ukhathazekile ngempilo yobuchopho bakho noma yomuntu omthandayo, cabanga ngalezi zinto.
- Indlela yokuphila enempilo: Gwema ukubhema. Lawula umfutho wegazi, i-cholesterol, nesifo sikashukela. Lezi yizinto ezibangela isifo senhliziyo kanye nesifo i-Alzheimer's.
- Ukudla okulinganiselayo: Nciphisa uwoyela, ushukela, nosawoti, bese ufaka izinto ezifana nemifino, izithelo, ubhontshisi kanye nenhlanzi ekudleni kwakho.
- Ukuzilolonga: Ngisho nento elula njengokuhamba nsuku zonke ingasiza ekugcineni igazi lihamba kahle ebuchosheni.
- Yiba ngumuntu okhuthele engqondweni: Funda iphephandaba, funda incwadi, xazulula amaphazili, xoxa nabangani, yiba nobudlelwano nabantu. Konke lokhu kuyindlela enhle yokuzivocavoca ubuchopho.
Into ebaluleke kakhulu ukuthi uma usola ukuthi wena noma othile emndenini wakho unenkinga yokukhumbula, ungakuthathi njengento "efana nendlela izinto ezenzeka ngayo ngokweminyaka" bese ubona udokotela ngokushesha . Uma lesi sifo sitholakala ngokushesha, imiphumela emihle ongayithola ekwelashweni. Uzokuhlola kahle futhi, uma kudingeka, akuthumele kudokotela wezinzwa.
Umlayezo Wokuya Nawe Ekhaya
- Isifo i-Alzheimer's siyisifo sobuchopho esiqhubekayo, kodwa kunocwaningo oluningi olusha oluthembisayo.
- Imithi esanda kuvunyelwa njenge -Aduhelm ne -Leqembi ibhekwa njengesinyathelo esikhulu sokuqhubekela phambili ngoba ihlasela imbangela yalesi sifo.
- Nakuba singenakukwazi ukushintsha izici eziyingozi njengobudala nomlando womndeni, singanciphisa ingozi yethu ngokuphila impilo enempilo, ukudla ukudla okunempilo, ukuzivocavoca, nokugcina ubuchopho bethu busebenza.
- Uma wena noma othile oseduze nawe enezinkinga zokukhumbula, ungakushayi indiva lokho bese ubona udokotela womndeni wakho ngokushesha.Ukuxilongwa kusenesikhathi kubaluleke kakhulu.
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