Ingabe une-asthma? Kungenzeka ukuthi usebenzisa i-inhaler yakho njengoba uyalelwe futhi uthatha eminye imithi, kodwa izimpawu zakho ze-asthma azibi ngcono. Uma uzwa ukuphefumula njalo, ukuqina kwesifuba, kanye nokukhwehlela, ungase ube ne-asthma ephakathi kuya kwenzima. Le ndlela entsha yokwelapha ethuthukisiwe, ebizwa ngokuthi 'i-Biologic Therapy', isetshenziselwa izimo ze-asthma ezinzima ukuzilawula.
Kalula nje, kuyini i-Biologic Therapy?
Lokhu kuyindlela yokwelapha yesimanje, eqondiswe ngqo yesifo sofuba esibi. Nakuba ama-inhaler avamile andisa okwesikhashana imigudu yokuphefumula futhi enze ukuphefumula kube lula, ukwelashwa ngebhayoloji kuyajula.
Cabanga nje, isizathu esiyinhloko esenza sibe ne-asthma ukuvuvukala emigwaqweni yomoya okubangelwa omunye umsebenzi wesimiso somzimba sokuzivikela. Ngakho-ke lokho okwenziwa yile mithi yezinto eziphilayo ukuhlasela ama-antibodies athile, amaseli noma ama-molecule emzimbeni afaka isandla kulokho kuvuvukala futhi amise umsebenzi wawo. Ngenxa yalokhu, i-asthma ilawulwa ezingeni eliyisisekelo.
Lokhu kwelashwa kunikezwa ngezindlela ezimbili eziyinhloko. Eyokuqala iwukujova ngaphansi kwesikhumba (umjovo ongaphansi kwesikhumba) kanti enye iwukujova ngemithambo yegazi (IV infusion).
Into ebalulekile ukuthi lokhu akuyona indlela yokwelapha yodwa. Kufanele isetshenziswe kanye ne-inhaler yakho ekhona kanye neminye imithi ye-asthma.
Ubani ofanele lolu hlobo lokwelashwa?
Ukwelashwa nge-biologic akuyona indlela yokwelapha bonke abaguli be-asthma. Udokotela wakho uzocabangela izici eziningana ngaphambi kokuncoma lokhu kwelashwa. Ithebula elingezansi lizokunikeza umbono omuhle.
| Izimo lapho ungathunyelwa khona ukuze uthole i-Biologic Therapy | |
|---|---|
| Akulawulwa ngemithi enqunyiwe | Uma izimpawu zakho ze-asthma zingalawulwa naphezu kokusebenzisa i-inhaler yakho oyinikezwe kanye neminye imithi ngendlela efanele. |
| Imiphumela yokuhlolwa kwegazi | Uma unezinga eliphezulu lama-Eosinophils (iseli elimhlophe legazi elibangela ukuvuvukala emaphashini) noma i-IgE (i-antibody ehlobene nokungezwani komzimba) egazini lakho. |
| Izimbangela ezenza lesi sifo sibe sibi kakhulu | Uma wazi ukuthi yini ebangela i-asthma yakho futhi uyigweme, kodwa izimpawu ziyaqhubeka. |
| Izimpawu ezivamile | Uma uvuka phakathi nobusuku ukhwehlela, noma uma usebenzisa i-rescue inhaler yakho izikhathi ezingaphezu kwezimbili ngesonto. |
| Ukubhebhetheka okuvamile | Uma kufanele uphuze amaphilisi e-corticosteroid izikhathi ezingaphezu kwezimbili ngonyaka noma kufanele uye e-ETU (Emergency Treatment Unit). |
| Ukulaliswa esibhedlela | Uma kufanele uhlale esibhedlela futhi uthole ukwelashwa ngenxa yesifo sofuba. |
Yiziphi izinhlobo zemithi yebhayoloji ezitholakalayo ze-asthma?
Kunezinhlobo eziningana zemithi yebhayoloji esezivunyiwe kuze kube manje. Ngayinye yazo isebenza ngendlela ehlukile kancane. Udokotela wakho uzokhetha umuthi ofanele kakhulu kuwe ngokusekelwe kuhlobo lwakho lwe-asthma kanye nemiphumela yokuhlolwa kwegazi.
| Igama lomuthi | Indlela yokusebenza kanye nokulethwa | Imiphumela emibi evamile |
|---|---|---|
| I-Omalizumab (Xolair®) | Yelapha i-asthma ebangelwa ukungezwani komzimba. Ifakwa ngaphansi kwesikhumba njalo emavikini ama-2-4. | Ubuhlungu bemisipha, ubuhlungu bamalunga, ukukhathala okukhulu, ukuvuvukala/ubuhlungu endaweni yokujova. |
| I-Mepolizumab (Nucala®) | Yelapha i-asthma ye-eosinophilic. Ijovwa ngaphansi kwesikhumba njalo emavikini ama-4. | Ikhanda elibuhlungu, ubuhlungu bomhlane, ubuthakathaka, ukukhathala, ukuvuvukala/ubuhlungu endaweni yokujova. |
| I-Reslizumab (Cinqair®) | Yelapha i-asthma ye-eosinophilic. Inikezwa nge-intravenously (IV) njalo emavikini ama-4. | Umphimbo obuhlungu, ubuhlungu bemisipha. |
| I-Benralizumab (i-Fasenra®) | Yelapha i-asthma ye-eosinophilic. Imithamo yokuqala emi-3 inikezwa njalo emavikini ama-4, bese kuba njalo emavikini ayi-8. | Ikhanda elibuhlungu, umphimbo obuhlungu. |
| I-Dupilumab (i-Dupixent®) | Yelapha i-asthma ye-eosinophilic kanye nezinye izimo ezibangelwa ukuvuvukala. Ijovwa njalo emavikini ama-2. | Umphimbo obuhlungu, ukuvuvukala/ubuhlungu endaweni yokujova, ukwanda kwenani lamaseli amhlophe egazi. |
| I-Tezepelumab (Tezspire®) | Umuthi omusha we-asthma enzima. Unciphisa ukuvuvukala. Ujovwa njalo emavikini ama-4. | Umphimbo obuhlungu, ubuhlungu bomhlane, ubuhlungu bamalunga. |
Kuthatha isikhathi esingakanani lokhu kwelashwa?
Lokhu kuvame ukuba ukwelashwa kwesikhathi eside. Kungathatha okungenani izinyanga ezingu-4-6 ukwazi ngokuqinisekile ukuthi lo muthi uyasebenza yini kuwe. Ngakho-ke kubalulekile ukuba nesineke ngokwelashwa kwakho.
Ingabe ngidinga ukuqhubeka nokusebenzisa i-inhaler yami?
Yebo, nakanjani.Lena yinto ebaluleke kakhulu. Ngisho nangemva kokuqala ukwelashwa nge-biologic, ungalokothi uyeke ukuthatha ama-inhaler akho neminye imithi oyinikezwe udokotela wakho. Ngokuhamba kwesikhathi, uma i-asthma yakho ilawulwa kahle, udokotela wakho angase anqume ukunciphisa umthamo wakho we-inhaler. Kodwa lokhu kufanele kwenziwe kuphela ngaphansi kweseluleko sikadokotela.
Yiziphi izinzuzo nezingozi zalokhu kwelashwa?
Njenganoma yikuphi ukwelashwa, lokhu kunezinzuzo kanye nezingozi ezincane.
Izinzuzo eziyinhloko:
- Kunciphisa ukuvuvukala endleleni yokuphefumula futhi kulawula ngempumelelo izimpawu ze-asthma.
- Umkhuhlane nokukhwehlela okuvamile kuzoncipha.
- Uzokwazi ukuzivocavoca nokuqeda imisebenzi yansuku zonke ngaphandle kokusebenza kanzima njengakuqala.
- Inani lezikhathi ovuka ngazo ebusuku liyancipha.
- Isidingo sokuya e-ETU (Emergency Treatment Unit) sizoncipha kancane.
- Izinga lempilo liyathuthuka kakhulu.
Izingozi ezingaba khona:
- Ukusabela okukhulu kokungezwani komzimba: Akuvamile kakhulu, abanye abantu bangase babe nokusabela okukhulu kokungezwani komzimba (i-anaphylaxis). Yingakho imithamo embalwa yokuqala inikezwa esibhedlela noma emtholampilo ngaphansi kokuqashwa kwezokwelapha.
- Ingozi yokutheleleka yizilokazane: Imithi enciphisa ama-eosinophil inganciphisa kancane ikhono lomzimba lokulwa nezilokazane, ikakhulukazi i-helminth. Ngakho udokotela wakho uzokucabangela lokho ngaphambi kokuqala lokhu kwelashwa.
Okubalulekile: Ungayeki ukuthatha lo muthi ngokuzumayo nganoma yisiphi isizathu ngaphandle kweseluleko sikadokotela wakho. Ukwenza kanjalo kungenza izimpawu zakho ze-asthma zibe zimbi kakhulu.
Nini ukukhuluma nodokotela wakho
Ezimweni ezilandelayo, qiniseka ukuthi uthintana nodokotela wakho futhi umazise.
- Uma izimpawu ze-asthma zingathuthuki noma zingabi zimbi ngemva kwezinyanga eziningana zokwelashwa.
- Uma kuvela izimpawu ezintsha zokungezwani komzimba (isib. ukuqubuka kwesikhumba, ukulunywa).
- Uma unemibuzo noma ukukhathazeka mayelana nokwelashwa.
Lokhu kwelashwa kungatholakala ngokunconywa udokotela ochwepheshe, eyunithi ekhethekile yesibhedlela (isikhungo sokufaka umuthi) noma emtholampilo kadokotela ochwepheshe. Lokhu kwelashwa kungabiza kancane. Kodwa ungakhuluma nodokotela wakho ngakho futhi uthole imininingwane eyengeziwe.
Umlayezo Wokuya Nawe Ekhaya
- Ukwelashwa nge-Biologic kuyindlela yokwelapha ethuthukisiwe esetshenziselwa izimo ezinzima ze-asthma okunzima ukuzilawula ngemithi ejwayelekile.
- Lokhu akulona ikhambi le-asthma, kodwa kusiza ukulawula lesi sifo kahle kakhulu.
- Ngesikhathi uthola lokhu kwelashwa, kubalulekile ukuqhubeka nokusebenzisa i-inhaler yakho kanye nayo yonke eminye imithi enikezwe udokotela wakho.
- Ukuthi lokhu kwelashwa kukufanele yini noma cha kuzonqunywa ngemva kokucabangela izimpawu zakho kanye nemibiko ethile yokuhlolwa kwegazi.
- Njengoba kungathatha izinyanga eziningana ukuthi imiphumela yokwelashwa ibonakale, kubaluleke kakhulu ukuba nesineke nokulandela imiyalelo yezokwelapha ngesikhathi sokwelashwa.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho