Uyazazi yini amaphilisi e-Bosutinib? Lezi zinto zibaluleke kakhulu ekwelapheni umdlavuza!

Ingabe wena noma othile oseduze nawe unikezwe umuthi i-'Bosutinib' ngudokotela wakho? Noma unesithakazelo sokufunda okwengeziwe ngalo muthi? Ngakho-ke namuhla, ake sixoxe ngalo muthi i-'Bosutinib' ngokuningiliziwe nangendlela elula kakhulu. Ukuqonda kahle imithi enjalo kusiza kakhulu ekwenzeni ukwelashwa kuphumelele.

Uyini lomuthi? Uyini iBosutinib?

Kalula nje, i-Bosutinib umuthi ohlasela amaprotheni athile kumaseli omdlavuza futhi uwavimbele ukukhula kwawo . Ngokukhethekile, uvame ukusetshenziswa kakhulu ukwelapha uhlobo lomdlavuza wegazi olubizwa ngokuthi i-Chronic Myelogenous Leukemia (CML). Ungowesigaba semithi ebizwa ngokuthi i-Targeted Therapy. Lokhu kusho ukuthi lo muthi awuthinti nje kuphela amaseli ngokujwayelekile, kodwa uthinta ngqo amaseli omdlavuza.

Ungase ukwazi ukuthola udokotela ukuthi akunike lo muthi ngaphansi kwegama lomkhiqizo elithi ``BOSULIF.'' Lelo igama lomkhiqizo elidumile lalo muthi.

Kodwa khumbula, ngezinye izikhathi odokotela bangasebenzisa lo muthi nakwezinye izimo. Ngakho-ke kungcono ukubuza udokotela wakho noma usokhemisi ukuthi kungani unikezwe lo muthi.

Yini okufanele uyitshele udokotela wakho ngaphambi kokuqala lo muthi?

Lokhu kubaluleke kakhulu. Ngaphambi kokuqala i-Bosutinib, kubalulekile ukwazisa udokotela wakho nganoma yiziphi izimo zempilo ongase ube nazo. Lokhu kuzobasiza ukuthi banqume ukuthi lo muthi ukulungele yini nokuthi yiziphi izinyathelo zokuphepha okufanele uzithathe.

Nazi ezinye izinto okufanele uzisho ngokuqinisekile:

• Uma unesifo sikashukela ( amazinga aphezulu kashukela egazini).
• Uma unesifo senhliziyo .
• Uma une -'High Blood Pressure' .
• Uma unesifo sezinso .
• Uma unesifo sesibindi .
• Uma uke waba nokusabela okungavamile kokungezwani komzimba ne-Bosutinib, eminye imithi, ukudla, udayi, noma izithasiselo.
• Uma ukhulelwe noma uzama ukukhulelwa , lokhu kubaluleke kakhulu!
• Uma ungumama oncelisayo .

Kubaluleke kakhulu ukuze uphephe ukutshela udokotela ngaphandle kokufihla lolu lwazi, kulungile?

Ngingawusebenzisa kanjani lo muthi?

Kulungile, manje ake sibone ukuthi la maphilisi e-`Bosutinib` asetshenziswa kanjani ngqo. Into ebaluleke kakhulu ukuphuza umuthi njengoba udokotela ekutshela.

• Leli philisi kufanele liphuzwe ngomlomo kanye nengilazi yamanzi .
• Landela imiyalelo ebhalwe ilebula kadokotela ngqo.
• Lo muthi kufanele uthathwe kanye nokudla. Ungawuthathi esiswini esingenalutho. Ukuwuthatha kanye nokudla kusiza umuthi ukuthi umunceke kangcono futhi kunganciphisa eminye yemiphumela emibi.
• Ungalisiki, ulichoboze, noma ulihlafune. Gwinya lonke iphilisi.
• Ungawuthathi lo muthi kanye nejusi likagrapefruit. I-Grapefruit iyisithelo esifana ne-orange enkulu. Ijusi elenziwe ngalesi sithelo lingasabela kulo muthi futhi lithinte indlela osebenza ngayo. Ngakho-ke qaphela kakhulu ngalokhu.
• Uma uthatha ama-H2 blockers (isib. i-cimetidine, i-famotidine, i-ranitidine) noma ama-antacid (isib. i-Digene, i-Gelusil) ngenxa yesilungulela noma i-gastritis , kufanele uwathathe amahora ama-2 ngaphambi noma amahora ama-2 ngemva kwe-bosutinib. Lokhu kusho ukuthi kufanele kube okungenani igebe lamahora ama-2 phakathi kokuthatha le mithi emibili. Buza udokotela wakho noma usokhemisi ukuthola ulwazi olwengeziwe.
• Thatha umuthi wakho ngezikhathi ezithile nangesikhathi. Ungathathi ngaphezu kwesilinganiso esinqunywe udokotela wakho, noma uwuthathe kaningi.
• Ungayeki ukuthatha lo muthi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.

Uma unikeza izingane lo muthi, kufanele ukhulume nodokotela wezingane ngakho futhi ulandele iseluleko sakhe. Kungadingeka ukunakekelwa okukhethekile.

Uma ucabanga ukuthi uphuze kakhulu lo muthi ngephutha, shayela i-Poison Control Center noma i-Offside Room eseduze ngokushesha.

Okubaluleke kakhulu: Lo muthi ungowakho kuphela. Unganiki omunye umuntu lo muthi nganoma yisiphi isizathu, noma ngabe lowo muntu unezimpawu ezifanayo nezakho.

Yini okufanele uyenze uma uphuthelwa umthamo wemithi?

Ukulahlekelwa umthamo owodwa wemithi kungenzeka kunoma ubani. Uma lokho kwenzeka, ungakhathazeki.

• Thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula.
• Kodwa-ke, uma kungaphansi kwamahora ayi-12 ngaphambi komthamo wakho olandelayo, ungawuthathi umthamo ongawusebenzisi. Yeqa bese uthatha umthamo olandelayo ngesikhathi esihleliwe.
• Ungalokothi uthathe umthamo ophindwe kabili wemithi. Ukwenza kanjalo kwandisa ingozi yemiphumela emibi.

Yiziphi ezinye izinto ezingasebenzisana nalo muthi?

I-Bosutinib ingasebenzisana neminye imithi, ukudla, kanye nezithasiselo zamakhambi ongase uzithathe. Lokhu kusebenzisana kunganciphisa ukusebenza kwe-Bosutinib noma kwandise ingozi yemiphumela emibi.

I-Bosutinib ingasebenzisana nalokhu okulandelayo:

• Amanye ama-antibiotic (isib. i-ciprofloxacin, i-clarithromycin, i-erythromycin)
• Ezinye izidakamizwa zokulwa ne-fungus (isib. i-fluconazole, i-ketoconazole, i-itraconazole)
• Eminye imithi yokulwa nesifo sokuwa (isib. i-carbamazepine, i-phenobarbital, i-phenytoin)
• `Eminye imithi yezinkinga zesisu` (isib. `Ama-Proton Pump Inhibitors` kanye nama-`H2 blockers` afana ne-`cimetidine`, `famotidine`, `ranitidine`, `omeprazole`, `pantoprazole`)
• Eminye imithi esetshenziswa ukwelapha ukutheleleka nge-HIV (isib. i-amprenavir, i-atazanavir, i-ritonavir)
• Ijusi le-Grapefruit (Ngikushilo lokhu ngaphambili, kodwa ngizokusho futhi!)
• Izithasiselo ezenziwe ngekhambi i-St. John's Wort (abanye abantu basebenzisela lokhu impilo yengqondo).
• Eminye imithi eminingi (isib., i-amiodarone, i-diltiazem, i-verapamil, i-rifampin).

Lolu hlu aluphelele. Kungase kube neminye imithi. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo (imithi kadokotela, ethengiswa ngaphandle kwemithi kadokotela, imithi yamakhambi, amavithamini, noma izithako zokudla). Futhi, tshela udokotela wakho uma ubhema, uphuza utshwala, noma usebenzisa ezinye izidakamizwa. Angabe esehlela ukwelashwa kwakho ngokufanele.

Yini okufanele ngiyiqaphele lapho ngithatha lo muthi?

Kubalulekile ukunaka noma yiziphi izinguquko emzimbeni wakho ngenkathi uthatha i-Bosutinib.

• Kuzodingeka ukuthi uhlolwe igazi njalo . Lokhu kuzosiza udokotela wakho ukuthi abone ukuthi umuthi uwuthinta kanjani umzimba wakho, ukuthi izitho zakho ezifana nesibindi sakho nezinso zisebenza kahle yini, nokuthi ngabe kukhona yini izinguquko ezingxenyeni zegazi lakho.
• Lomuthi ungakwenza ube namathuba amaningi okuphuka noma ukuphuma kwegazi. Uma ubona noma yikuphi ukuphuka okungajwayelekile, ukuphuma kwegazi ezinsinini, ukuphuma kwegazi ekhaleni, noma ukuphuma kwegazi, tshela udokotela wakho ngokushesha.
• Uma unomkhuhlane, ukubanda, umphimbo obuhlungu , noma izimpawu zokutheleleka njengomkhuhlane noma ukukhwehlela, ungaziniki imithi. Shayela udokotela wakho ngokushesha ukuze uthole iseluleko. Lo muthi ungase wehlise amandla omzimba wakho okulwa nokugula. Ngakho-ke, zama ukuhlala kude nabantu abagulayo.
• Ukunakwa okukhethekile mayelana nokukhulelwa:
• Ungakhulelwa ngenkathi uthatha lo muthi.
• Gwema ukukhulelwa okungenani amasonto amabili ngemva kokuyeka iphilisi.
• Abesifazane abahlela ukukhulelwa noma abacabanga ukuthi bakhulelwe kufanele batshele udokotela wabo ngokushesha. Lo muthi ungabangela imiphumela emibi kakhulu enganeni engakazalwa. Buza udokotela wakho noma usokhemisi ukuze uthole ulwazi olwengeziwe.
• Ngokuphathelene nokuncelisa: Ungancelisi ingane yakho ngenkathi uthatha lo muthi futhi okungenani amasonto amabili ngemva kokuyeka umuthi.
• Ukuzala: Lo muthi ungathinta ikhono lakho lokuthola abantwana. Uma ukhathazekile ngalokhu, khuluma nodokotela wakho.

Yimiphi imiphumela emibi engaba khona yalo muthi?

Njenganoma yimuphi umuthi, i-Bosutinib ingabangela imiphumela emibi. Kodwa-ke, akuwona wonke umuntu oyitholayo. Eminye imiphumela emibi iyingozi futhi kufanele utshele udokotela wakho ngokushesha uma uyibona. Eminye ayibi kakhulu futhi ingase iphele ngemva kwezinsuku ezimbalwa.

Imiphumela emibi okufanele uyibike kudokotela wakho ngokushesha:

• Ukusabela kokungezwani komzimba: Ukuqubuka kwesikhumba, ukulunywa, amaqhubu, ukuvuvukala kobuso, izindebe, noma ulimi. Uma kuvela lezi zimpawu, funa usizo lwezokwelapha ngokushesha.
• Ubuhlungu emhlane ( obukhulu, obungavamile).
• Indle ephuzi enegazi noma emnyama . Lokhu kungaba uphawu lokopha ngaphakathi.
• Uhudo olubi kakhulu .
• Isiyezi (esinzima, esivame ukwenzeka).
• Ikhanda elibuhlungu (elibi kakhulu, elingabekezeleleki).
• Izimpawu zokuhlaselwa yinhliziyo: Ukuphefumula okunzima, ubuhlungu noma ukuqina esifubeni, entanyeni, emhlane, noma ezingalweni.
• Izimpawu zokwehluleka kwenhliziyo: Ukuphefumula kanzima, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukukhuluphala ngokuzumayo; ukuvuvukala kwamaqakala, izinyawo, izandla.
• `Izimpawu zokutheleleka`: umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, ubuhlungu noma ubunzima bokuchama.
• Ubuhlungu bamalunga ( obukhulu).
• `Izimpawu zokulimala kwezinso`: Ushintsho enanini lomchamo okhiqizwayo (wehle kakhulu noma wanda kakhulu).
• `Isitulo esinombala okhanyayo` .
• Izimpawu zokulimala kwesibindi: Umchamo ophuzi noma onsundu omnyama, umuzwa wokugula ojwayelekile noma izimpawu ezifana nomkhuhlane, ukulahlekelwa yisifiso sokudla, ubuhlungu besisu esingenhla kwesokudla, ukuphuzi kwamehlo noma isikhumba (i-jaundice).
• `Inani lamaseli abomvu egazi aphansi - I-Anemia`: Ubunzima bokuphefumula, ukuquleka, ukuzizwa udidekile, uzizwa sengathi uzowa njalo, uzizwa ukhathele noma ubuthakathaka ngendlela engajwayelekile.
• Isicanucanu (esinzima, esiqhubekayo).
• `Umchamo obomvu noma onsundu omnyama` .
• Ubuhlungu besisu ( obukhulu).
• `Ukuphuma kwegazi noma ukuklwebheka okungavamile`.
• `Ukuvuvukala okungavamile` .
• Ukuhlanza (okunzima, okuqhubekayo).

Imiphumela emibi evame ukungadingi ukwelashwa (kodwa kufanele ibikwe kudokotela uma iqhubeka noma ikhathaza):

• `Ukuqunjelwa` .
• `Ukukhathala` .

Khumbula, lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma ubona noma yini engavamile noma ehlukile, tshela udokotela wakho ngayo.

Ngingayigcina kanjani imithi yami?

Kubaluleke kakhulu futhi ukugcina imithi yakho ngendlela efanele.

• Gcina kude nezingane nezilwane ezifuywayo.
• Gcina ekamelweni lokushisa. Okungukuthi, phakathi kwama-degree Celsius angu-20 no-25 (ama-degree Fahrenheit angu-68 no-77). Ungabeki endaweni eshisayo kakhulu, ebanda, noma enomswakama.
• Ungasebenzisi imithi esiphelelwe yisikhathi. Yilahle.

Uyilahla kanjani imithi engasetshenziswanga nephelelwe yisikhathi?

Akukuhle ngaso sonke isikhathi ukumane ulahle imithi ephelelwe yisikhathi, engasetshenziswanga emgqonyeni kadoti noma ukuyilahla endlini yangasese. Ingaba yingozi emvelweni.

• Into engcono kakhulu ongayenza ukuhambisa le mithi "ohlelweni lokubuyisela imithi." Ungabuza ikhemisi lakho noma iziphathimandla zezempilo zasendaweni ukuthi zinazo yini izinhlelo ezinjalo.
• Uma ungalutholi uhlelo olunjalo, hlola iphakethe lemithi noma incwajana engaphakathi kwalo ukuze ubone ukuthi linemiyalelo yokuthi ungalilahla kanjani emgqonyeni kadoti noma endlini yangasese. Uma ungaqiniseki, buza udokotela wakho noma usokhemisi.
• Uma uqiniseka ukuthi kuphephile ukufaka udoti, susa umuthi ebhodleleni noma ephaketheni ofike kulo, uwuxube nento efana nekhofi esetshenzisiwe, udoti wekati, noma inhlabathi, bese uwufaka esikhwameni noma esitsheni esivalwe kahle bese uwufaka kudoti.

Leli pheshana liyisifinyezo kuphela. Uma uneminye imibuzo mayelana neBosutinib, sicela ukhulume nodokotela wakho, usokhemisi, noma omunye umhlinzeki wezempilo.

Izinto ezibaluleke kakhulu okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ake sikukhumbuze futhi ngezinye zezinto esikhulume ngazo okudingeka uzikhumbule.

• I-Bosutinib umuthi okhethekile onikezwa umdlavuza onjenge-chronic myelogenous leukemia (CML).
• Lo muthi kufanele uthathwe kanye nokudla . Akufanele unqunywe, uchotshozwe, noma uhlafunwe. Ungawusebenzisi kanye nojusi we-grapefruit.
• Kufanele utshele udokotela wakho ngayo yonke eminye imithi oyithathayo, noma yiziphi ezinye izifo onazo, nokuthi ukhulelwe noma uncelisa.
• Ungakhulelwa ngesikhathi uthatha iphilisi. Qaphela amasonto amabili ngemva kokuyeka.
• Uma uzwa ukopha okungajwayelekile, umkhuhlane, ukuqubuka kwesikhumba, ubunzima bokuphefumula, noma izimpawu ze-jaundice, tshela udokotela wakho ngokushesha.
• Thola ukuhlolwa kwegazi ngesikhathi.
• Ungayeki ukuthatha imithi ngaphandle kweseluleko sikadokotela wakho.

Ngikufisela ukululama okusheshayo! Ngiyethemba ukuthi lolu lwazi luzokusiza.

I- Bosutinib, i-Bosulif, i-CML, i-Chronic Myelogenous Leukemia, Ukwelashwa Komdlavuza, Imithi Yomdlavuza, Imiphumela Engemihle