Kunezifo ezithile okunzima ukuzilawula ngemithi ejwayelekile. Ikakhulukazi izimo ezifana ne-arthritis ezibangelwa izinkinga ezithile ohlelweni lwethu lokuzivikela komzimba, noma ezinye izifo ezingavamile ezibangela umkhuhlane ovamile, ziwela kulesi sigaba. Ngakho-ke, ezikhathini ezinjengalezi, odokotela basebenzisa imithi ekhethekile nenamandla kakhulu. Omunye wemithi enjalo yi-Canakinumab. Lona unikezwa njengomjovo.
Iyini i-Canakinumab?
Kalula nje, i-canakinumab umuthi oshintsha indlela amasosha omzimba wethu asebenza ngayo ngezinga elithile futhi ulawule izimpawu. Akuyona ikhambi, kodwa ingakusiza ukulawula lesi sifo futhi uphile impilo evamile.
Lo muthi usetshenziswa kakhulu kulezi zimo ezilandelayo:
- Ezinye izinhlobo ze-arthritis ezinganeni nakubantu abadala: Isibonelo, izimo ezifana nesifo sikaStill.
- Izimpawu Zomkhuhlane Ovamile: Lezi zaziwa ngamagama ayinkimbinkimbi kancane. Isibonelo:
- Izifo Ezihambisana Nezikhathi Ezihambisana Ne-Cryopyrin (CAPS)
- I-Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
- I-Hyperimmunoglobulin D syndrome (HIDS)
- Umkhuhlane WaseMedithera Womndeni (FMF)
Into ebaluleke kakhulu ukuthi uchwepheshe kuphela ohlola isimo sakho onganquma ukuthi uzowusebenzisa yini lo muthi noma cha nokuthi uzowuthatha isikhathi esingakanani.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala lokhu kwelashwa
Njengoba lo muthi unamandla kakhulu, kubalulekile ukuthi wazise udokotela wakho ngomlando wakho wezempilo ophelele ngaphambi kokuqala ukwelashwa. Ungawushayi indiva, ucabanga ukuthi kuyinto encane. Ngoba ngisho naleyo nto encane ingathinta ukwelashwa kwakho.
| Tshela udokotela wakho uma unezinye zezimo ezilandelayo: | Kungani lokho kubalulekile? |
|---|---|
| Ukutheleleka kwamanje noma kwakamuva (isb., i-chickenpox, i-herpes, izilonda zomkhuhlane) | Ngenxa yokuthi lo muthi unciphisa amasosha omzimba, ukutheleleka kungaba kubi kakhulu. |
| Isifo sofuba , ukuhlolwa kwesikhumba okubonakalayo kwesifo sofuba, noma ukuxhumana eduze nomuntu onesifo sofuba. | Ngaphambi kokuqala imithi, kufanele uhlolwe isifo sofuba futhi, uma kudingeka, uqale ukwelashwa. |
| Ezinye izinkinga zamasosha omzimba , i-HIV noma i-AIDS. | Kufanele uqaphele kakhulu uma usebenzisa lo muthi ezimweni ezinjalo. |
| Ukuba nomlando womdlavuza . | Udokotela wakho kufanele aqaphele lokhu. |
| Izimo ezifana nenani eliphansi lamaseli amhlophe egazi . | Lesi simo singathinteka kakhulu ngemithi. |
| Ukukhulelwa noma ukuzama ukukhulelwa. | Khuluma nodokotela wakho ngemiphumela yalo muthi ngesikhathi sokukhulelwa. |
| Ukuncelisa umntwana. | Kufanele uxoxe nodokotela wakho ukuthi lo muthi uzothinta yini ingane ngobisi lwebele. |
| Njengoba usanda kuthola umuthi wokugoma noma uhlelelwe ukuwuthola esikhathini esizayo. | Ikakhulukazi, imijovo yegciwane eliphilayo ayikwazi ukuthathwa nalomuthi. |
| Ukuba ne-allergy kweminye imithi, ukudla noma izinto ezithile. | Lokhu kubalulekile ukuqinisekisa ukuthi une-allergy ku-canakinumab noma kunoma yiziphi izithako zayo. |
Uyisebenzisa kanjani le mithi?
Lona akuwona umuthi ongawuthatha ekhaya uzinike wona. Lona umjovo ngaphansi kwesikhumba. Ngokuvamile unikezwa udokotela noma umhlengikazi oqeqeshiwe esibhedlela noma emtholampilo .
Ngaphambi kokwelashwa ngakunye, uzonikezwa incwajana yolwazi ekhethekile (i-MedGuide) ngalo muthi. Kubalulekile ukuwufunda nokuwuqonda ngokucophelela isikhathi ngasinye.
Ingabe lo muthi kufanele unikezwe izingane?
Kwezinye izimo ezikhethiwe, lo muthi unganikezwa izingane ezineminyaka engu-2 ubudala. Kodwa-ke, lesi sinqumo senziwa udokotela wezingane. Uma unikeza ingane lo muthi, qiniseka ukuthi uxoxa ngawo ngokugcwele nodokotela wakho.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Lokhu akunakwenzeka ukuthi kwenzeke njengoba kunikezwa esibhedlela. Kodwa-ke, uma ucabanga ukuthi usuthathe lo muthi omningi kakhulu, shayela ngokushesha i-National Poisons Information Centre e-Colombo National Hospital noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Eminye imithi engase ihlangane nalo muthi
Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini nemithi yendabuko), njengoba eminye imithi ingathintana nalena.
| Ungayithathi nhlobo i-canakinumab nalezi. | |
|---|---|
| Imithi yezinto eziphilayo | Isib: adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab |
| Imithi yokugomela igciwane ephilayo | Isib. Isimungumungwane, ugonyo, i-rubella (MMR), umuthi wokugomela i-chickenpox |
| Tshela udokotela wakho ngoba kungase kube nokuxhumana nalokhu. | |
| Eminye imithi ecindezela amasosha omzimba | i-abatacept, i-baricitinib, i-rilonacept, i-rituximab, i-sarilumab, i-tocilizumab, i-tofactinib |
| I-Warfarin | Umuthi onikezwa ukuvimbela ukujiya kwegazi |
Izinto okufanele uzikhumbule lapho uthatha imithi
- Qaphela izifo: Lo muthi ucindezela amasosha omzimba wakho, okwenza ube namathuba amaningi okuthola izifo. Ngakho-ke, uma uzwa izimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, noma impumulo egobhozayo , ungaziphathi nje kuphela. Shayela udokotela wakho ngokushesha ukuze uthole iseluleko. Zama ukuhlala kude nabantu abagulayo.
- Ukuhlolwa kwesifo sofuba (TB): Uzohlolwa isifo sofuba (TB) ngaphambi kokuqala ukwelashwa. Uma udokotela wakho ekunike imithi yesifo sofuba, kuzodingeka uqale ukuthatha lowo muthi ngaphambi kokuqala i-canakinumab. Futhi kuzodingeka uthathe umuthi isikhathi esiphelele esinqunyiwe.
- Ukuqashwa kwezokwelapha: Udokotela wakho uzoqhubeka nokuqapha isimo sakho ngenkathi uthatha lo muthi. Uzophinde akucele ukuhlolwa kwegazi uma kudingeka. Uma izimpawu zakho zingathuthuki noma zingabi zimbi kakhulu, tshela udokotela wakho .
Yimiphi imiphumela emibi engingayithola?
Njenganoma yimuphi umuthi, lo ungaba nemiphumela emibi. Eminye iyingozi, eminye ivamile. Into ebalulekile ukuqaphela lokhu futhi uthathe isinyathelo ngokushesha uma kudingeka.
| Imiphumela emibi kakhulu okufanele uyibike kudokotela wakho ngokushesha | |
|---|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Ubunzima bokuphefumula | Ukuphefumula kanzima, ukuqina kwesifuba. |
| Izinguquko ekushayeni kwenhliziyo | Ukuzizwa sengathi inhliziyo yakho ishaya ngokushesha noma ngokungajwayelekile. |
| Isiyezi noma ukuquleka | Ukuzizwa udidekile, uzizwa ungaphili, uyawa. |
| Izimpawu zokutheleleka | Umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, ubuhlungu lapho uchama. |
| Ukuvuvukala kwesikhumba, ukubomvu, noma ukufudumala | Ikakhulukazi kwenye indawo ngaphandle kwendawo yokujova. |
| Imiphumela emibi evame ukungabi mibi kakhulu, kodwa okufanele ibikwe kudokotela wakho uma iqhubeka: | |
| Uhudo | Ikhanda elibuhlungu |
| Isicanucanu nokuhlanza | Impumulo egobhozayo, njengomkhuhlane |
| Isiyezi | Ubuhlungu, ukubomvu, noma ukuvuvukala okuncane endaweni yokujova |
Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma uhlangabezana nanoma yini engavamile, ungesabi ukukhuluma nodokotela wakho ngayo.
Umlayezo Wokuya Nawe Ekhaya
- I-Canakinumab iwumuthi wokugomela onamandla osetshenziselwa ukwelapha izifo ezihlobene nokuzivikela komzimba ezifana ne-arthritis kanye nezinye izimo zokuvuvukala ezingavamile.
- Ngaphambi kokuqala lokhu kwelashwa, kubalulekile ukuthi wazise udokotela wakho ngazo zonke izimo zakho zezokwelapha kanye nayo yonke imithi oyithathayo.
- Lo muthi wandisa ingozi yokutheleleka, ngakho-ke qaphela njalo izimpawu ezifana nomkhuhlane, ukukhwehlela kanye nomphimbo obuhlungu.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi kakhulu, njengobunzima bokuphefumula noma ukusabela okukhulu kokungezwani komzimba, funa iseluleko sezokwelapha ngokushesha.
- Hlala uxhumana nodokotela wakho njalo. Ungayeki ukuya emithini. Xoxa naye nganoma yiziphi izinkinga.
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