Wake wanikezwa imithi ngudokotela ngenxa yesimo esifana nokucindezeleka noma ukukhathazeka? Uma kunjalo, kungenzeka ukuthi wake wezwa ngemithi ebizwa ngokuthi 'iCelexa' noma 'iLexapro'. Lena yimibili yemithi evame kakhulu yalezi zimo emhlabeni wonke nasezweni lethu. Ngakho-ke, umbuzo abantu abaningi abanawo ukuthi uyini umehluko phakathi kwalezi ezimbili, ingabe ziyafana, nokuthi iyiphi efanele mina. Ake sixoxe ngalokhu namuhla ukuze sisuse konke ukungabaza onakho engqondweni yakho.
Okokuqala, ake sibone ukuthi iCelexa neLexapro ziyini.
Kalula nje, yomibili le mithi ingeyeqembu elibizwa ngokuthi ama-antidepressants . Uma sikhuluma iqiniso, ivela eqenjini elithile lemithi ebizwa ngokuthi "ama-SSRI" (ama-Selective Serotonin Reuptake Inhibitors). Nakuba igama lingase lizwakale liyinkimbinkimbi kancane, inqubo ilula kakhulu.
Ake sithi kukhona izithunywa ngaphakathi kobuchopho bethu ezithwala ulwazi emuva naphambili. Lezi zithunywa sizibiza ngokuthi ama-neurotransmitters. I-Serotonin iyisithunywa esibaluleke kakhulu esilawula izinto ezifana nemizwa yethu, ukuziphatha, kanye nenkumbulo. Ezimweni ezifana nokucindezeleka, leli zinga le-Serotonin lingancipha.
Lokho okwenziwa yi-SSRI ukuvimba le serotonin yesithunywa ukuthi ingamuncwa ngokushesha ngemva kokuba isiqediwe. Ngemuva kwalokho i-serotonin ihlala emangqamuzaneni ezinzwa zobuchopho isikhathi eside. Lokho kusho ukuthi umyalezo "ojabulisayo" uhlala usebenza isikhathi eside. Yilapho isimo sethu sengqondo siqala ukuthuthuka.
I-Celexa igama lomkhiqizo womuthi i-Citalopram . I-Lexapro igama lomkhiqizo womuthi i -Escitalopram . Zombili zivunyelwe ukwelapha isifo sokucindezeleka okukhulu (MDD) kubantu abadala, kanti i-Lexapro nayo ivunyelwe ukwelapha isifo sokukhathazeka esijwayelekile (GAD).
Kulungile, pho umehluko omkhulu phakathi kwalokhu okubili uyini?
Leli iqiniso elithakazelisayo kakhulu. I-'Citalopram' (i-Celexa) kanye ne-'Escitalopram' (i-Lexapro), ngokwesayensi yamakhemikhali, ziyizithombe ezibukwayo ze-molecule efanayo. Njengesandla sethu sobunxele nesandla sethu sokudla. Zombili ziyizandla, kodwa zihlukile. Kumakhemikhali, lezi zibizwa ngokuthi 'ama-enantiomers'.
- I-Citalopram (i-Celexa) iyinhlanganisela yezinhlobo "zokusebenzisa isandla sobunxele" kanye "nesandla sokudla" ozikhulumile.
- I-Escitalopram (Lexapro) iyona esebenza kakhulu kulezo ezimbili, okusho ukuthi iyisidakamizwa esenziwe ngengxenye eyinhloko kuphela, njengesandla "sokunene".
Yingakho kunomehluko omncane endleleni le mithi emibili esebenza ngayo emizimbeni yethu.
Kalula nje, i-Escitalopram (Lexapro) ifana nenguqulo ehlanjululwe kakhulu ye-Citalopram (Celexa).
Ake sibheke eminye yemibono eyinhloko:
- Ukusetshenziswa Okuvunyelwe: Nakuba i-'Citalopram' ivunyelwe kuphela ukucindezeleka kubantu abadala, i-'Escitalopram' ivunyelwe ukucindezeleka kubantu abadala nezingane ezingaphezu kweminyaka eyi-12 ubudala, kanye nokukhathazeka kubantu abadala nezingane ezingaphezu kweminyaka eyi-7 ubudala.
- Ukusebenza kahle: Ezinye izifundo zikhombisile ukuthi i-Escitalopram isebenza kangcono kune-Citalopram ekulawuleni izimpawu zokucindezeleka.
- Ingozi yokushaya kwenhliziyo: Yomibili le mithi ingaba nomthelela omncane emsebenzini kagesi wenhliziyo. Lokhu kubizwa ngokuthi 'i-QT prolongation'. Lokhu kunengozi encane yokushaya kwenhliziyo okungavamile. Kodwa-ke, le ngozi iphakeme kancane nge-'Citalopram' kune-'Escitalopram', ikakhulukazi ngemithamo ephezulu.
Imiphumela emibi nezinto okufanele uziqaphele
Njengoba zombili lezi zidakamizwa zisemndenini owodwa, imiphumela emibi nayo ifana kakhulu. Akuwona wonke umuntu oyitholayo, kodwa ivame ukuphela ngemva kwesikhathi esithile njengoba umzimba usujwayele imithi.
| Imiphumela emibi evamile ye-Celexa ne-Lexapro | |
|---|---|
| Imiphumela emibi evamile | |
| Izinkinga zokulala | Ukuzizwa ulele emini noma ungakwazi ukulala ebusuku |
| Ukukhathala komzimba | Ukukhathala, isiyezi |
| Ezinye izici ezivamile | Isiyezi, ikhanda elibuhlungu, ukujuluka ngokweqile, umlomo owomile |
| Izinkinga zesistimu yokugaya ukudla | Isicanucanu, ukuhlanza, ukuqunjelwa, noma isifo sohudo |
| Izinkinga zokusebenza kocansi | Ukuncipha kwesifiso sobulili, ubunzima bokufinyelela ekufikeni kokuvuthwa, ukuphuphuma kokukhipha isisu okuphuzile |
| Imiphumela emibi engavamile kodwa engaba yingozi | |
| Izinguquko ekushayeni kwenhliziyo | Isimo se-'QT Prolongation' esishiwo ngenhla (kunengozi ephezulu kancane nge-Citalopram) |
| Ukwehla kwamazinga e-sodium egazini | Kungabangelwa yisimo esibizwa ngokuthi "i-SIADH", ikakhulukazi kubantu abangaphezu kweminyaka engama-65. |
'I-Serotonin Syndrome' yisimo esidinga ukunakwa okukhethekile.
Lokhu kuyinto okufanele uyazi nakanjani . I-Serotonin Syndrome iyizinga eliphezulu kakhulu le-serotonin emzimbeni. Lokhu kungenzeka kakhulu uma uqala ukuthatha umuthi, uma ukhulisa umthamo, noma uma uwuthatha kanye neminye imithi ethinta amazinga e-serotonin (isib. eminye imithi ye-migraine, eminye imithi yokucindezeleka).
Uma wena noma othile omaziyo eba nalezi zimpawu ngesikhathi esifanayo, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela ngokushesha.
- Ukungahlaliseki, ukungahlaliseki
- Isicanucanu, ukuhlanza, isifo sohudo
- Abafundi abavulekile
- Ukuthuthumela, ukudikiza kwemisipha, ukuqina
- Ukujuluka ngokweqile, ukubanda, nokuthuthumela
- Ukudideka okukhulu, ukulahlekelwa ukwazi
- Ukwanda kwesilinganiso senhliziyo, ukwanda komfutho wegazi
- Umkhuhlane, ukuquleka, ukulahlekelwa ukwazi
Qaphela imicabango yokuzibulala.
Lokhu nakho kubaluleke kakhulu. Ingozi yokucabanga ngokuzibulala inganda kancane emasontweni ambalwa okuqala okuqala kokusebenzisa imithi yokucindezeleka noma lapho kushintsha umthamo, ikakhulukazi kubantu abasha nezingane ezingaphansi kweminyaka engama-24. Qaphela kakhulu izimpawu ezilandelayo.
- Ukucindezeleka kuya ngokuya kuba kubi.
- Ukucabanga ngokuqeda impilo yakho.
- Ukuhlaselwa uvalo.
- Ukungalali.
- Ukungahlaliseki, ulaka, ukucasuka.
- Ukwenza ngaphandle kokucabanga nokujabula ngendlela engavamile.
Uma wena noma ingane yakho nizwa noma yiziphi zalezi zimpawu, khuluma nodokotela wakho ngokushesha .
Ungaba umlutha walo muthi?
Cha. Lezi azibhekwa njengezidakamizwa eziluthayo njengezidakamizwa. Kodwa-ke, kunenkinga.Uma uyeka ngokuzumayo ukuthatha lo muthi isikhathi esingaphezu kwamasonto ayisithupha, ungase uzizwe ungakhululekile ngokomzimba. Lokhu kubizwa ngokuthi 'i-antidepressant discontinuation syndrome'. Izimpawu ezifana nokushintshashintsha kwemizwelo, isiyezi, nokukhathazeka zingase zibe khona.
Ngakho-ke, ungalokothi, nganoma yisiphi isizathu, uyeke ukuthatha lo muthi ngokuzumayo ngaphandle kokubonisana nodokotela wakho. Ukuwuyeka kufanele kwenziwe ngaphansi kweseluleko sikadokotela wakho, ngokunciphisa kancane kancane umthamo.
Okunye ukusetshenziswa kwe-Celexa ne-Lexapro (Ukusetshenziswa okungekho ku-label)
"Ukusetshenziswa okungekho ku-label" kubhekisela ekunikezeni umuthi wesimo esingavunyelwe ngokusemthethweni saleso simo, kodwa odokotela bazi ngokuhlangenwe nakho ukuthi umuthi uwusizo kuleso simo. Yomibili imithi isetshenziselwa ezinye izimo eziningana, okuhlanganisa:
- Ezinye izimo lapho i-Citalopram (i-Celexa) ingasetshenziswa khona:
- Isifo Sokucindezeleka Okungapheli (OCD)
- Isifo Sokwethuka
- Isifo Sokukhathazeka Komphakathi
- Isifo sokucindezeleka ngemva kokucindezeleka (PTSD)
- Ukuphuma komchamo ngaphambi kwesikhathi
- Ezinye izimo lapho i-Escitalopram (Lexapro) ingasetshenziswa khona:
- Isifo Sokukhathazeka Komphakathi
- Isifo sokuzikhukhumeza ngokweqile (OCD)
- Isifo Sokwethuka
- Izimpawu ezihambisana nokunqamuka kokuya esikhathini (isib. ukushisa okukhulu)
Ngakho-ke, iyiphi okufanele uyikhethe phakathi kwalezi ezimbili?
Lona umbuzo obaluleke kakhulu. Lesi yisinqumo udokotela wakho azosenza ngemva kokukuhlola nokucabangela izici eziningi, njengezimpawu zakho, ubudala, nezinye izimo zezokwelapha.
- Uma unenkinga yokukhathazeka nokucindezeleka, i-Lexapro ingaba yisinqumo esingcono.
- Uma unomlando wesifo senhliziyo, i-Lexapro ingaba yindlela engcono ngoba inezingozi eziphansi.
- Kwabanye abantu, i-'Celexa' isebenza kahle. Kwabanye, i-'Lexapro' ifaneleka kakhulu.
Ngakho-ke, kungcono ukukhuluma ngokukhululekile nodokotela wakho ngalokhu. Ungenzi izinqumo ngokusekelwe kulokho okufundayo ku-inthanethi. Udokotela wakho uzokhetha umuthi ofanele futhi ophephile kakhulu kuwe.
Umlayezo Wokuya Nawe Ekhaya
- I-Celexa (Citalopram) kanye ne-Lexapro (Escitalopram) yimithi ye-SSRI elapha ukucindezeleka nokukhathazeka ngokulinganisela amazinga e-serotonin ebuchosheni.
- I-Lexapro iyinguqulo ye-Celexa ehlanjululwe kakhulu futhi eqondiwe, ngakho-ke kunomehluko omncane ekusetshenzisweni kwayo kanye nemiphumela emibi ethile.
- Kubaluleke kakhulu ukuqaphela imicabango yokuzibulala lapho uqala lo muthi, ikakhulukazi kulabo abangaphansi kweminyaka engama-24. Uma ubona noma yiziphi izinguquko, tshela udokotela wakho ngokushesha.
- Qaphela izimpawu zesimo esibi esibizwa ngokuthi 'i-Serotonin Syndrome'. Uma uhlangabezana nezimpawu ezinjalo, hamba esibhedlela ngokushesha.
- Ungalokothi uyeke ukuthatha lo muthi ngokuzumayo ngaphandle kweseluleko sikadokotela. Ukwenza kanjalo kungabangela ukungakhululeki emzimbeni.
- Tshela udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nezimo zezokwelapha ozisebenzisayo.
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