Uma unesifo sikashukela sohlobo 1, ungase uzibuze, "Ingabe ingane yami izosithola naso?" Noma uma umama noma ubaba wakho enaso, ungase uzibuze, "Kungenzeka yini ukuthi nami ngisithole?" Le mibuzo inengqondo ngempela, futhi iyinkinga abantu abaningi abanayo. Ngakho ake sixoxe ngalokhu ngemininingwane eyengeziwe futhi namuhla.
Akuzona izakhi zofuzo kuphela, kodwa nendawo ezungezile iyathinta
Uma kukhulunywa ngesifo sikashukela sohlobo 1, akusona isifo sofuzo kuphela. Kalula nje, kuyinhlanganisela yezakhi zofuzo esizithola kubazali bethu (imvelo) kanye nendawo esikhulela kuyo (ukukhula) .
Cabanga ngale ndlela. Izakhi zethu zofuzo zifana nokubeka isiteji. Okusho ukuthi, zakha ukuthambekela okuthile, isikhala esithile emzimbeni wethu sokuthuthukiswa kwalesi sifo. Kodwa izici zemvelo nazo zidlala indima enkulu ekunqumeni ukuthi ngabe umdlalo uzodlalwa kuleso sigaba noma cha. Izinto eziningi zingabangela lokhu, njengendawo okhulela kuyo, lokho okudlayo nokuphuzayo, kanye nezifo ezithile ezibangelwa amagciwane ozitholayo. Kodwa abacwaningi basathola ukuthi ziyini ngempela lezi zici zemvelo nokuthi zikuthinta kangakanani. Ngakho-ke , noma ngabe kukhona ukuthambekela kofuzo, akunakushiwo ukuthi lesi sifo sizokhula nakanjani.
Yiziphi izakhi zofuzo ezithinta lokhu?
Abantu abaningi bacabanga ukuthi kukhona i-gene ekhethekile ebizwa ngokuthi 'i-diabetes gene', ukuthi uma 'ivuliwe', isifo siyakhula, futhi uma 'isiphelile', asiveli. Kodwa iqiniso liyinkimbinkimbi kakhulu kunalokho.
Isifo sikashukela sohlobo 1 sibangelwa yiqembu lezakhi zofuzo, hhayi elilodwa kuphela . Phakathi kwazo, i-HLA gene idlala indima ebalulekile. Lezi zakhi zofuzo zinomthwalo wokukhiqiza amaprotheni adingwa yisimiso sethu sokuzivikela komzimba. Manje, bheka, isifo sikashukela sohlobo 1 siyisifo esizimele . Okusho ukuthi, isimiso sokuzivikela somzimba esivikela umzimba wethu ngephutha siqala ukuhlasela amangqamuzana ethu anempilo. Kusifo sikashukela, lokhu kuhlasela kwenzeka kumaseli ase-pancreas akhiqiza i-hormone i-insulin . I-insulin iyi-hormone ebalulekile ekuguquleni ushukela esiwudlayo ube amandla. Ngakho-ke, lapho la maseli akhiqiza i-insulin ebhujiswa, kuvela isifo sikashukela sohlobo 1.
Kunezinhlobo eziningi ezahlukene zalezi zakhi zofuzo ze-HLA echibini lethu lezakhi zofuzo. Ngakho-ke kuye ngokuthi yiziphi izinhlobo zezakhi zofuzo ozizuza njengefa kubazali bakho, ungase ube sengozini yokuba nesifo sikashukela. Ezinye izakhi zofuzo zandisa ingozi, kanti ezinye zihlinzeka ngesivikelo ngokuvimbela lesi sifo ukuthi singabi khona.
Naphezu kwethonya lezakhi zofuzo, kunezimo lapho oyedwa kuphela kumawele amabili afanayo eba nesifo sikashukela kanti omunye uhlala ephilile. Lokhu kubonisa ithonya lezici zemvelo.
Yiziphi amathuba okuba nesifo sikashukela?
Lezi zinombolo zingadida kancane, kodwa kubalulekile ukuba nombono oqondile. Ithebula elingezansi libonisa amathuba okuba ingane ibe nesifo sikashukela sohlobo 1 ngezikhathi ezahlukene.
| Ilungu lomndeni kanye nesimo | Amathuba okuba ingane ibe nesifo sikashukela sohlobo 1 |
|---|---|
| Ubaba unesifo sikashukela sohlobo 1 | 1 kwabayi-17 (1 kwabayi-17) |
| Umama unesifo sikashukela sohlobo 1 (uma ingane yazalwa ingakafiki eminyakeni engama-25) | 1 kwabangu-25 (1 kwabangu-25) |
| Umama unesifo sikashukela sohlobo 1 (uma ingane yazalwa eneminyaka engu-25 noma ngemva kwalokho) | Umuntu oyedwa kwabayi-100 (oyedwa kwabayi-100) - Kufana nengozi evamile |
| Ukuba nabazali bobabili abanesifo sikashukela sohlobo 1 | Ingafinyelela kubantu aba-1 kwaba-4 (o-1 kwaba-4) |
| Ukuba nomfowenu noma udadewenu onesifo sikashukela sohlobo 1 (ngaphandle kwabazali) | Ingozi engaba ngu-5% (efana nengozi yokuba nobaba) |
| Amawele Afanayo Anesifo | Ingozi ifinyelela ku-50% (1 kwababili) |
| Umzali one-Type 2 Polyglandular Autoimmune Syndrome ngaphezu kwesifo sikashukela sohlobo 1 | Ingozi engu-50% (1 kwababili) |
Ungakhathazeki ngalezi zibalo. Into ebaluleke kakhulu okufanele uyikhumbule ukuthi iningi labantu abanesifo sikashukela sohlobo 1 abanawo umlando womndeni walesi sifo. Lokhu kusho ukuthi ezimweni eziningi, lesi sifo singavela ngokuzumayo, ngaphandle komlando womndeni.
Ngakho-ke kufanele ngenzeni?
Awukwazi ukushintsha izakhi zofuzo zakho. Kuyiqiniso lokho. Kodwa ungakuqaphela lokhu.
- Ukwazisa: Uma othile emndenini wakho enesifo sikashukela sohlobo 1, kubalulekile ukuqaphela.
- Qaphela izimpawu: Ikakhulukazi ezinganeni, qaphela izimpawu ezifana nokoma ngokweqile, ukuchama njalo, ukwehla kwesisindo ngokuzumayo, kanye nokukhathala okukhulu.
- Funa iseluleko sezokwelapha: Uma unokungabaza, ungesabi, bonana nodokotela wakho ngokushesha okukhulu. Ukuxilongwa kusenesikhathi kanye nokwelashwa kubaluleke kakhulu.
Ekugcineni, izakhi zofuzo ziyingxenye nje yendaba. Ngakho-ke, kuwukuhlakanipha ukugwema ukwesaba ngokungadingekile ngomlando womndeni, ukwaziswa, ukwamukela indlela yokuphila enempilo, nokufuna iseluleko sezokwelapha uma kudingeka.
Umlayezo Wokuya Nawe Ekhaya
- Ukukhula kwesifo sikashukela sohlobo 1 akuthonywa nje yizakhi zofuzo, kodwa futhi nayindawo esihlala kuyo.
- Akukho 'gene yesifo sikashukela' eyodwa ethize. Kuyinhlanganisela yezakhi zofuzo eziningana ezihilelekile, ikakhulukazi izakhi zofuzo (i-HLA) .
- Ngisho noma othile emndenini wakho enesifo sikashukela sohlobo 1, akusho ukuthi wena noma ingane yakho nizosithola nakanjani. Ingozi iphansi kakhulu.
- Iningi labantu abanesifo sikashukela sohlobo 1 abanawo amanye amalungu omndeni analesi sifo, ngakho-ke singaba semindenini.
- Uma unomlando womndeni noma usola noma yiziphi izimpawu, kungcono ukukhuluma nodokotela wakho ngaphandle kokwesaba.
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