Ingabe uzwa ukuvuvukala, ukuqina, kanye nobuhlungu ngaphansi kwesikhumba sakho? Ake sixoxe nge-Eosinophilic Fasciitis!

Wake wazizwa ngokuzumayo iqhubu, ukuvuvukala, noma ubuhlungu ngaphansi kwesikhumba sengalo noma umlenze wakho? Mhlawumbe kwenzeke ngemva kokuzilolonga kahle. Wake wabhekana nento efana nale? Ngakho-ke, nansi isimo esingakaziwa kakhulu esingaba sibalulekile kuwe.

Kuyini i-Eosinophilic Fasciitis?

Kalula nje, i-Eosinophilic Fasciitis yisimo lapho izicubu ezimboza imisipha nezicubu zethu ngaphansi kwesikhumba sethu - esikubiza ngokuthi i-fascia ngokwezokwelapha - ngokuzumayo ziyavuvukala, zijiye, futhi ziqine. Cabanga ngakho njenge-mesh ebamba isikhumba nemisipha yethu ndawonye futhi izisize zihambe, njenge-mesh esiyifaka ebhuthini yemoto yethu lapho siyothenga.

Lokhu kuhlukaniswa ngokuthi 'isifo esizivikela ngokuzenzakalelayo '. Lokhu kusho ukuthi uhlelo lokuzivikela lomzimba wethu, uhlelo lokuzivikela, luqala ngephutha ukuhlasela izingxenye zomzimba wethu ezinempilo. Kufana nokuhlasela amalungu omndeni wethu lapho ecabanga ukuthi aphangiwe.

Uma kungatholakali futhi kwelashwe kusenesikhathi, kungabangela izinguquko zesikhumba ezihlala njalo kanye nokulahlekelwa ukunyakaza kwamalunga . Ngakho-ke, kubaluleke kakhulu ukufuna iseluleko sezokwelapha ngokushesha nje lapho kuvela izimpawu.

Lesi simo sithinta kanjani kakhulu? Sithinta bani?

I-Eosinophilic Fasciitis ingathinta i-fascia noma kuphi emzimbeni, kodwa ivame ukuthinta izandla nezinyawo . Kubantu abaningi, izimpawu, njengobuhlungu noma ukuvuvukala, zingase zivele okokuqala ngemva kokuzivocavoca okunzima noma umsebenzi odinga ukuma usuku lonke.

Lezi zimpawu, njengobuhlungu bemisipha nokuvuvukala, zingafana nezezinye izifo ezivamile, ngakho-ke kubalulekile ukubona udokotela ngokushesha uma ubona noma yiziphi izinguquko ezintsha noma ubuhlungu esikhumbeni sakho, emisipheni, noma emalungeni. Kungase kudingeke futhi ukuthi ubonane nodokotela wamathambo, udokotela ogxile emalungeni nezinye izifo zokuvuvukala.

Okwamanje akukho ukwelashwa kwalesi sifo. Kodwa-ke, izindaba ezinhle ukuthi kubantu abaningi, izimpawu ziyaphela phakathi neminyaka embalwa, okusho ukuthi lesi sifo siya 'ekuphumuleni', noma sibe sesimeni sokulala. Kodwa-ke, abanye abantu bangase babhekane nokuphindaphinda kwezimpawu.

Umehluko Phakathi kwe-Eosinophilic Fasciitis ne-Scleroderma

Uma bekhuluma ngalezi zifo ezimbili, abanye abantu bangase bazididanise nesinye isifo esibizwa ngokuthi i-'Scleroderma'. I-'Eosinophilic Fasciitis' kanye ne-'Scleroderma' zombili ziyizifo ezingavamile kakhulu ze-'autoimmune'. Futhi, kuzo zombili lezi zifo, izicubu zomzimba ziyaqina futhi ziqine.

Ngakho-ke umehluko uyini? Umehluko usezinhlotsheni zezicubu ezithintekile.

• Ku-Eosinophilic Fasciitis, njengoba sixoxile ngaphambili, i-fascia, izicubu ezincane nezinwebekayo ezingaphansi kwesikhumba, iyathinteka. Ngokuhamba kwesikhathi, le fascia iyaqina futhi ikhule, okwenza kube nzima ukuhambisa ingxenye yomzimba ethintekile.
• Kodwa ku-'Scleroderma', isimiso somzimba sokuzivikela sivuselela amanye amaseli ukuthi akhiqize iphrotheni ebizwa ngokuthi 'i-collagen' (into enika isikhumba nezicubu zethu amandla). Le collagen eningi ifakwa esikhumbeni nasezithweni zangaphakathi, okwenza zibe ziqinile futhi ziqine, njengesibazi esidala. Kodwa esikhundleni sokwelapha inxeba, le collagen eningi ingalimaza nezicubu ezinempilo.

I-Eosinophilic Fasciitis kanye ne-COVID-19

Abantu abanezifo zokuzivikela komzimba njenge-Eosinophilic Fasciitis babhekwa njengabasengozini enkulu kancane yokuthola i-COVID-19 kunabantu abaningi.

Ochwepheshe basangaqiniseki ukuthi abantu abanalesi simo banamathuba amaningi okuba nezimpawu ezinzima ze-COVID-19. Ngakho-ke, kungcono ukulandela izincomo zeziphathimandla zezempilo, njenge-Centers for Disease Control and Prevention (CDC), ukuze uzivikele ekuthelelekeni.

Ubani onamathuba amaningi okuthola lesi sifo?

I-Eosinophilic Fasciitis ingathinta noma ubani, kodwa ivame ukuthinta abantu abaneminyaka ephakathi kuka-30 no-60.

Ngaphezu kwalokho, abantu abanezinkinga ezithile zempilo ezingamahlalakhona banamathuba amaningi okuthola lesi sifo. Ezinye zalezi zimo zifaka:

• I-Aplastic anemia (i-aplastic anemia - i-anemia lapho ukukhiqizwa kwamaseli egazi kuncipha khona)
• I-Hemolytic anemia (i-anemia lapho amangqamuzana abomvu egazi ewohloka khona ngokushesha)
• I-Lymphoma (umdlavuza wesistimu ye-lymphatic)
• I-leukemia (umdlavuza wamaseli egazi)
• Ezinye izinhlobo 'zesifo se-thyroid'

Kuvamile kangakanani lokhu?

I-Eosinophilic Fasciitis empeleni iyisifo esingavamile kakhulu . Kuze kube manje, inani elincane kakhulu lamacala, cishe angu-300, abikwe emaphephandabeni esayensi emhlabeni jikelele. Kodwa-ke, mhlawumbe ngenxa yokungaxilongwa kahle noma ukungabikwa kahle, inani lamacala lingase libe phezulu kakhulu.

I-Eosinophilic Fasciitis ithinta kanjani umzimba wami?

Njengoba sesixoxile ngaphambili, lesi simo sibangelwa ukuvuvukala kwe-fascia, izicubu ezincane neziguquguqukayo ezingaphansi kwesikhumba. Lolu ngqimba lwe-fascia lumboza futhi luvikele imisipha yethu kanye nezinye izitho zangaphakathi. Luphinde lubambe isikhumba kanye nemisipha endaweni yayo futhi luyisekele lapho inyakaza.

Cabanga ngakho, le fascia isiza ukugcina izitho zethu ziguquguquka, kodwa hhayi nje ukulenga phansi. Kodwa kumuntu one-'Eosinophilic Fasciitis', le fascia membrane iyavuvukala, iqine kancane kancane, futhi iqine. Ekugcineni, lokhu kuvuvukala kwenza kube nzima ukuhambisa isikhumba nemisipha ezungezile. Uma ingelashwa, le fascia inganamathela endaweni eyodwa futhi iqine. Lokhu ngezinye izikhathi kubizwa ngokuthi 'i-contracture'. Okusho ukuthi, isimo lapho ilunga lingenakunwetshwa noma ligobeke.

Esikhundleni sokuqina okuvamile kwe-fascia, izingxenye zomzimba ezithintekile ziba buhlungu noma kube nzima ukuzinyakazisa.

Izingxenye zomzimba ezivame ukuthinteka yilezi:

• Izandla (ikakhulukazi intende yesandla, okungukuthi, ingaphakathi lesandla)
• Imilenze (ikakhulukazi ngaphambili, ngakwesokudla ethanjeni lesinqe)
• Izindawo ezizungezile noma ezizungezile

Nakuba kungavamile, lesi simo singathinta nesikhumba ebusweni, esifubeni kanye nasesiswini.

Ezinye iziguli ezine-Eosinophilic Fasciitis zingase zibe nokuvuvukala kwamalunga okufana ne-Rheumatoid Arthritis. Uma lokhu kuvuvukala kwamalunga kungalawulwa, i-cartilage emalungeni ingonakala, okuholela ekuqaqambeni kwamalunga isikhathi eside.

Futhi, uma lesi sifo sithinta i-fascia esandleni sakho noma esihlakaleni, ukuvuvukala kungabangela ukuthi i-median nerve, enye yemizwa eyinhloko esandleni, icindezelwe, okubangela isimo esibizwa ngokuthi i-Carpal Tunnel Syndrome (ukuba ndikindiki, ubuhlungu, kanye nobuthakathaka esandleni).

Into ebalulekile ukuthi i-Eosinophilic Fasciitis yisimo esingashintsha futhi sikhule ngokushesha okukhulu. Ungaqala ukuqaphela imiphumela ebonakalayo esikhathini esifushane, njengamasonto ambalwa. Ngakho-ke, uma ubona noma yiziphi izimpawu noma izinguquko emzimbeni wakho, bona udokotela ngokushesha.

Ziyini izimpawu ze-Eosinophilic Fasciitis?

Ngakho-ke, kufanele usole kanjani lesi sifo? Nazi ezinye zezimpawu eziyinhloko:

• Ubuhlungu bemisipha .
• Isikhumba esithambile .
• Ukuvuvukala noma ukuvuvukala .
• Izimpawu ze-'Carpal Tunnel Syndrome' (njengokungazweli, ubuhlungu, ubuthakathaka esandleni).
• I-Arthritis (i-arthritis - ukuvuvukala kwamalunga, ubuhlungu, ukuqina kwasekuseni).
• Isikhumba sizwakala sikhulu futhi siqinile kunokujwayelekile.
• Kwezinye izindawo, isikhumba sibukeka sinamaqhubu futhi siqinile, njengesikhumba se-orenji (isikhumba esinamaqhubu noma ukubukeka "kwe-peau d'orange").

Iyini imbangela yalokhu?

Uma ngikhuluma iqiniso, ochwepheshe abakayazi imbangela eqondile ye-Eosinophilic Fasciitis. Njengezifo eziningi zokuzivikela komzimba, ingavela ngokuzumayo, ngezinye izikhathi ngaphandle kwesizathu esibonakalayo.

Kodwa-ke, ezinye izifundo zithole ukuthi lezi zifo zokuzivikela komzimba zingabangelwa "yizinto ezithile". Okusho ukuthi, lesi sifo singakhula ngenxa yento ethile. Isibonelo:

• Ezinye izinhlobo zokutheleleka .
• Ezinye izimo zokungezwani komzimba .
• Ukusebenzisa imithi ethile.
• Ukusebenzisa imithi ethile.

Abanye abantu abane-Eosinophilic Fasciitis bathi izimpawu zabo zokuqala zenzeka ngemva kokusebenza kanzima ngokomzimba , njengokugijima, ukuphakamisa izinsimbi, noma ukuzivocavoca, noma ngenkathi benza umsebenzi odinga umzamo omkhulu ezingalweni noma emilenzeni yabo.

Kungumqondo omuhle ukukhuluma nodokotela wakho ngezinto ezingabangela ukuhlaselwa yisifo sokuzivikela komzimba njengalesi.

Odokotela basithola kanjani lesi sifo? (Ukuxilongwa)

Uma unalezi zimpawu, udokotela angenza izivivinyo eziningana ukuze athole ukuthi une-Eosinophilic Fasciitis:

1. I-Fascia Biopsy: I-biopsy yilapho udokotela wakho ethatha isampula encane yezicubu zakho bese eyithumela elabhorethri ukuze ayibheke ngaphansi kwe-microscope. Lokhu kuhilela ukuthatha ingxenye encane yesikhumba esithintekile kanye ne-fascia engaphansi kwayo bese uyihlola. Ezimweni eziningi, lena yindlela ethembekile kakhulu yokuthola lesi simo.

2. Ukuhlolwa kwegazi: Uma une-Eosinophilic Fasciitis, ungase ube namazinga aphezulu ohlobo lweseli elimhlophe legazi elibizwa ngokuthi ama-Eosinophils egazini lakho (yilapho lesi sifo sithola khona igama laso). Kodwa-ke, ukuhlolwa kwegazi kuphela akukwazi ukuqinisekisa lesi sifo. Ngokuvamile, kudingeka i-biopsy.

3. Ukuhlolwa kwezithombe: Ukuhlolwa okufana ne-MRI (Magnetic Resonance Imaging) kungasiza ekuboneni ukuvuvukala emzimbeni, ikakhulukazi e-fascia nasezicutshini ezizungezile. Kodwa-ke, njengokuhlolwa kwegazi, akucaci njengokuhlolwa kwegazi ukuze kutholakale isifo.

Ukwelashwa kwe-Eosinophilic Fasciitis

Akuvamile kakhulu ukuthi izimpawu ziphele zodwa ngaphandle kokwelashwa. Kodwa esikhathini esiningi, odokotela belapha i-Eosinophilic Fasciitis ngohlobo lomuthi olubizwa ngokuthi ama-corticosteroids . Lolu uhlobo lwe-steroid.

Ama-corticosteroids asebenza ngokunciphisa ukuvuvukala emzimbeni kanye nokucindezela isimiso somzimba sokuzivikela esisebenza ngokweqile. I-Prednisone iyi-corticosteroid evame kakhulu ukunikezwa.

Ngaphezu kwe-corticosteroids, udokotela wakho angase anikeze nezinye izindlela zokwelapha, njenge:

• `Ama-NSAID`: Imithi elwa nokuvuvukala engeyona i-steroidal (ama-NSAID) etholakala ekhemisi – isibonelo, i-ibuprofen kanye ne-diclofenac – inganciphisa izimpawu ezifana nobuhlungu nokuvuvukala. Kodwa-ke, uma usuvele uthatha 'ama-corticosteroids', khuluma nodokotela wakho ngaphambi kokuthatha 'ama-NSAID'. Ungathathi 'ama-NSAID' izinsuku ezingaphezu kweziyi-10 ngesikhathi ngaphandle kwemvume kadokotela wakho.
• Imithi yokucindezela amasosha omzimba: Kuye ngokuthi isimo sakho sibucayi kangakanani, udokotela wakho angase akunikeze eminye imithi (isib. i-Methotrexate) ecindezela amasosha omzimba asebenza ngokweqile abangela i-Eosinophilic Fasciitis.
• Ukwelashwa ngokomzimba: Ukwelashwa ngokomzimba kungasiza ukwelula nokukhulula i-fascia yakho uma iqinile, futhi kusize ekugcineni ukunyakaza kwamalunga. Udokotela wakho noma uchwepheshe wezokwelapha ngokomzimba uzokufundisa ukuzivocavoca kanye nokulula okuhambisana nezimpawu zakho.
• Ukwelapha ezinye izimo: Ungase uzizwe ukhululekile ngokwelapha izimpawu zezinye izimo, njenge-carpal tunnel syndrome noma i-arthritis.
• Ukuhlinzwa: Uma i-Eosinophilic Fasciitis yakho inzima ngokwanele ukubangela ukuqunjelwa, kungadingeka ukuthi uhlinzwe ukuze ukhulule noma ususe ingxenye ye-fascia yakho (ukukhululwa kwe-fascial). Lokhu kuvame ukuba yindlela yokugcina.

Ungazilawula kanjani izimpawu?

• Kubaluleke kakhulu ukuthatha umuthi njengoba nje udokotela esho, isikhathi esinqunyiwe.
• Uma udokotela wakho noma uchwepheshe wezokwelapha umzimba ekunika ukwelula noma ezinye izivivinyo, zenze kaningi ngangokunokwenzeka njengoba zikutshela ukuze usize ukwelula i-fascia ethintekile. Nakuba lokhu kungaba nzima, kungaba wusizo uma uqhubeka nokukwenza.
• Uma une-Carpal Tunnel Syndrome, kungadingeka ugqoke i-brace ukuze ugcine isihlakala sakho sisendaweni yaso ngenkathi ulele. Sisebenzise njengoba kuqondiswe udokotela wakho.

Ngizozizwa ngingcono ngokushesha kangakanani ngemva kokwelashwa?

Ukuvuvukala okubangelwa yi-Eosinophilic Fasciitis kufanele kuqale ukuncipha zingakapheli amahora ambalwa kusukela kuthathwe umthamo wokuqala we-corticosteroids. Lokhu kukhululeka kungaba okwesikhashana, futhi izimpawu zingase zibuye njengoba umuthi uphela. Ngakho-ke, kubalulekile ukuthatha umuthi isikhathi esigcwele esinqunywe udokotela wakho.

Ingabe i-Eosinophilic Fasciitis ingavinjelwa?

Ngeshwa, ayikho indlela eqondile yokuvimbela lesi sifo. Ochwepheshe abazi kahle ukuthi yini ebangela izifo ezibangelwa amasosha omzimba noma ukuthi zibangelwa kanjani, ngakho abakwazi ukusho ukuthi uzoqala nini noma kungani.

Yini okufanele ilindelwe umuntu onalesi sifo?

Uma kutholakala ukuthi une-Eosinophilic Fasciitis, kufanele ulindele ukuthi izimpawu zakho zizohlala isikhathi esithile. Uma ubona noma yiziphi izinguquko ezimpawu zakho, ikakhulukazi uma ziba zimbi kakhulu, khuluma nodokotela wakho ngokushesha.

Njengoba sesishilo ngaphambili, ayikho ikhambi lalokhu. Abantu abaningi baphila nakho iminyaka embalwa, bese izimpawu ziyanyamalala (ziye 'ekukhululweni'). Abanye abantu abaphinde bakuthole, kodwa abanye bangase babe nezimpawu ezibuya kamuva ('eziphinde zibuye').

Ngeke ukwazi ukuya emsebenzini noma esikoleni?

Uma ungakwazi ukwenza umsebenzi wakho noma umsebenzi wesikole ngaphandle kokucindezela kakhulu i-fascia yakho ethintekile, kufanele ukwazi ukubuyela emsebenzini noma esikoleni uze ululame kwi-Eosinophilic Fasciitis. Kodwa-ke, udokotela wakho uzokutshela ukuthi yimiphi imisebenzi okufanele uyigweme uze ululame. Kubalulekile ukulandela le miyalelo.

Qiniseka ukuthi ukhuluma nodokotela wakho futhi uthole imvume ngaphambi kokuqala imisebenzi enzima yomzimba njengokugijima, ukuphakamisa izinsimbi, noma ukuzivocavoca.

Kufanele ubonane nini nodokotela?

• Uma ubona noma yiziphi izimpawu ezintsha ezandleni zakho, ezinyaweni, noma emalungeni – ikakhulukazi uma unobuhlungu noma ukuvuvukala okungapheli ngemva kwezinsuku ezimbalwa zokuphumula – bona udokotela ngokushesha.
• Uma usuvele utholakale une-Eosinophilic Fasciitis, tshela udokotela wakho ngokushesha uma izimpawu zakho ziba zimbi kakhulu, noma uma ubona noma iyiphi ingxenye yomzimba wakho iba lukhuni noma indikindiki.

Kufanele uye nini e-Emergency Treatment Unit (ETU) ?

Uma ngokuzumayo ungakwazi ukunyakaza noma ukusebenzisa ingxenye yomzimba wakho, noma uma uzwa ubuhlungu obungabekezeleleki, hamba uye ekamelweni lezimo eziphuthumayo eliseduze ngokushesha .

Yimiphi imibuzo okufanele uyibuze udokotela?

Uma uya kudokotela, ungabuza imibuzo efana nale:

• Ingabe ngine-Eosinophilic Fasciitis, noma kukhona okunye?
• Izimpawu zami zingaba zimbi kangakanani ngokushesha?
• Ngidinga uhlobo luni lokwelashwa? Ngizodinga ukwelashwa isikhathi esingakanani?
• Ingabe ngizodinga ukuhlinzwa?
• Ngingaphinde ngiqale nini ukwenza umsebenzi ojwayelekile womzimba?
• Lesi simo sithinta kanjani impilo yami yansuku zonke?

Ezinye zezinto ezibaluleke kakhulu okudingeka sizikhumbule kule ndaba yilezi:

I-Eosinophilic fasciitis yisimo esingavamile kodwa esibi kakhulu esingakuthinta ngokushesha. Uma ubona ubuhlungu obusha, ukuvuvukala, noma ukuqina ezandleni noma ezinyaweni zakho, ikakhulukazi uma kungapheli ezinsukwini ezimbalwa, ungalibali ukubona udokotela. Njengoba lesi simo singakhula ngokushesha kakhulu , lapho usheshe uhlolwe izimpawu zakho, kulapho udokotela wakho engathola khona imbangela ngokushesha futhi aqale ukwelashwa okudingekayo.

Udokotela wakho uzokwengeza ama-corticosteroids kanye nezinye izindlela zokwelapha uma kudingeka ukusiza ukulawula izimpawu zakho. Ungesabi, kodwa qaphela izimpawu zakho bese ulandela imiyalelo kadokotela wakho ngokucophelela. Ngikufisela ukululama okusheshayo!

I- Eosinophilic Fasciitis, i-Eosinophilic Fasciitis, Izifo Zesikhumba, i-Fascia, Ubuhlungu Bamalunga, Ubuhlungu Bemisipha, Izifo Zokuzivikela Ezizimele