Cabanga ukuthi bekuzokwenzekani uma ibutho lethu, isimiso sethu sokuzivikela komzimba , okufanele sivikele imizimba yethu ezifweni , singaqondanga ngokuzumayo bese siqala ukuhlasela izitho zethu ezinhle? Leso yisimo esingavamile kodwa esibi kakhulu esibizwa ngokuthi i-Goodpasture Syndrome. Kulesi sifo, isimiso sethu sokuzivikela komzimba silimaza kakhulu izitho ezimbili ezibaluleke kakhulu emzimbeni wethu, amaphaphu nezinso . Kubaluleke kakhulu ukuqaphela lokhu ngoba kungaba yingozi empilweni uma kungaqashelwa futhi kwelashwe ngokushesha.
Iyini ngempela i-Goodpasture Syndrome?
Kalula nje, i-Goodpasture Syndrome iyisifo esibangelwa ukuzivikela komzimba . Okusho ukuthi, uhlelo lokuzivikela lomzimba wethu, uhlelo lokuzivikela komzimba, luyaphazamiseka futhi luhlasele amangqamuzana nezicubu zethu.
Kulesi sifo, amasosha omzimba enza ama-antibodies ngokumelene neprotheni ekhethekile ebizwa ngokuthi i-collagen , etholakala emaphashini nasezinso zethu. Cabanga ngale collagen njengeglue ebamba izingxenye zomzimba wethu ndawonye. Ngakho-ke lapho la ma-antibodies ehlasela leyo collagen, amaphaphu nezinso ziqala ukulimala kakhulu.
Nakuba lesi kuyisifo esingavamile kakhulu, kubalulekile ukuqaphela nokuqala ukwelashwa ngokushesha nje lapho kuvela izimpawu, ngaphandle kwalokho imiphumela ingaba mibi kakhulu.
Yini ebangela lesi simo?
Odokotela abakaqondi ngokugcwele ukuthi kungani amasosha ethu omzimba ehlasela izitho zawo ngephutha ngale ndlela. Kodwa-ke, kunezici eziningana okucatshangwa ukuthi zidlala indima.
- Ithonya lezakhi zofuzo : Njengoba lesi sifo singena kweminye imindeni, kukholelwa ukuthi kungenzeka ukuthi kukhona ukuthambekela kwezakhi zofuzo kuso.
- Izici zemvelo: Ukuchayeka kumakhemikhali athile, njengezinyibilikisi ze-hydrocarbon kanye nemithi yokubulala ukhula efana ne-paraquat.
- Uthuli lwensimbi: Ukuchayeka njalo othulini lwensimbi.
- Izidakamizwa: Ukusetshenziswa kwezidakamizwa ezifana ne-cocaine.
- Ukubhema: Ukubhema ugwayi kuyimbangela enkulu yalokhu.
- Ukutheleleka ngegciwane: Lesi simo singavela ngemva kokutheleleka ngegciwane.
Lesi sifo sivame ukubonakala kwabesilisa abasebasha, ikakhulukazi labo abaneminyaka ephakathi kuka-20 no-30 kanye nalabo abaneminyaka engaphezu kuka-60.
Ziyini izimpawu? Ukubona kanjani lokhu?
Izigaba zokuqala zalesi sifo zibonisa izimpawu ezijwayelekile nezingaqondakali. Ngakho-ke ngezinye izikhathi kungase kungabonakali sengathi kuyinto engathi sína. Kodwa lesi simo siqhubeka ngokushesha okukhulu.
Bheka ithebula elingezansi ukuze uthole ukuthi lezi zimpawu ziyini.
| Uhlobo oluyisici | Izimpawu ezingabonakala |
|---|---|
| Izici zokuqala nezivamile |
|
| Uma amaphaphu ethintekile | |
| Uma izinso zithinteka |
Nakuba lesi sifo singabangela ukuphuma kwegazi emaphashini okusongela ukuphila, umonakalo wamaphaphu wesikhathi eside uvame ukuba mncane kakhulu. Kodwa-ke, umphumela onzima kakhulu walesi sifo ukwehluleka kwezinso . Uma lokhu kwenzeka, ungadinga i-dialysis yempilo yakho yonke noma ukufakelwa izinso.
Udokotela usithola kanjani lesi sifo?
Uma uhlangabezana nesinye noma ngaphezulu sezimpawu esixoxe ngazo, ungalibali . Bonana nodokotela ngokushesha okukhulu. Ikakhulukazi uma ukhwehlela igazi, unenkinga yokuphefumula, noma ukhipha igazi emchameni wakho, kuyisimo esiphuthumayo.
Udokotela angase acele ukuhlolwa okuningana ukuqinisekisa ukuxilongwa:
- Ukuhlolwa komchamo: Lokhu kuhlolwa kuhlola amazinga aphezulu amaprotheni namaseli abomvu egazi emchameni. Lokhu kungasiza ekunqumeni ukuthi izinso zonakele yini.
- Ukuhlolwa kwegazi: Igazi lakho lihlolwa ama-antibodies athile ahlasela amaphaphu nezinso.
- I-X-ray yesifuba: Lokhu kungabheka umonakalo emaphashini, njengezindawo ezimhlophe ezingavamile ezibangelwa ukopha.
- I-Biopsy: Ngezinye izikhathi ingxenye encane yezicubu ithathwa enso noma emaphashini bese ihlolwa ngaphansi kwe-microscope. Lokhu kungaqinisekisa ukuthi akhona yini ama-antibodies e-Goodpasture Syndrome nokuthi umonakalo owenzekile ezinso ungakanani.
Yiziphi izindlela zokwelapha lokhu?
Uma lesi sifo sesitholakele, ukwelashwa kufanele kuqale ngokushesha okukhulu nangokujulile. Imigomo eyinhloko yokwelashwa yile:
- Ukulwa nama-antibodies ayingozi.
- Ukulawula ukuqongelela koketshezi oluningi emzimbeni.
- Ukulawula umfutho wegazi ophakeme.
- Ukuvimba umonakalo emaphashini nasezinso.
Ukwelashwa kuvame ukuhilela okulandelayo:
1. Imithi yokucindezela amasosha omzimba: Imithi efana ne-cyclophosphamide kanye ne-corticosteroids iyanikezwa. Le mithi isebenza ngokunciphisa ukusebenza kwesimiso sethu sokuzivikela komzimba kanye nokuvimba ukukhiqizwa kwama-antibodies ayingozi. Ngezinye izikhathi imithamo ephezulu yama-steroid kungadingeka inikezwe ngemithambo yegazi ukuze kulawulwe ukopha emaphashini.
2. I-Plasmapheresis: Lena inqubo eyinkimbinkimbi kancane. Kalula nje, ihilela ukuthatha inani elincane legazi lakho, ulifake emshinini okhethekile, bese uhlukanisa ingxenye ewuketshezi, ebizwa ngokuthi i-plasma, equkethe ama-antibodies ayingozi. Ngemuva kwalokho, izingxenye ezinhle ezisele zegazi (amangqamuzana egazi abomvu namhlophe) zixutshwa nenye indawo ye-plasma bese zibuyiselwa emzimbeni wakho. Lokhu kususa ama-antibodies ayingozi egazini. Lokhu kwelashwa kungadinga ukwenziwa nsuku zonke amasonto amaningana.
Lokhu kwelashwa kungathatha izinyanga eziyi-6 kuya kweziyi-12. Kungathatha noma yikuphi kusukela emavikini ambalwa kuya eminyakeni emibili ukuze kuphole ngokuphelele. Phakathi nalesi sikhathi, ezinye iziguli zingadinga umoya-mpilo owengeziwe noma ngisho nomshini wokuphefumula. Kungadingeka futhi ukumpontshelwa igazi.
Umlayezo Wokuya Nawe Ekhaya
- I-Goodpasture Syndrome iyisimo esingavamile kodwa esibi kakhulu lapho amasosha ethu omzimba ehlasela khona amaphaphu nezinso.
- Izimpawu ezinjengokukhwehlela igazi, ubunzima bokuphefumula, igazi emchameni, kanye nokuvuvukala komzimba ziyizibonakaliso eziyisixwayiso ezibaluleke kakhulu.
- Uma unezinye zalezi zimpawu, ungalibali bese ubona udokotela ngokushesha . Uma ukwelashwa kuqalwa ngokushesha, imiphumela iba ngcono.
- Ukwelashwa kuhlanganisa imithi elawula amasosha omzimba kanye nezindlela ezifana ne-plasmapheresis, ehlanza igazi.
- Uma wena noma othile omaziyo enokungabaza noma imibuzo ngalokhu, khuluma ngokukhululekile nodokotela wakho ngakho.
I-Goodpasture Syndrome IsiSinhala, isifo samaphaphu, isifo sezinso, amasosha omzimba, isifo sokuzivikela komzimba esiSinhala, ukukhwehlela igazi, igazi emchameni
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