Uyalwazi yini lolu hlobo lwesimila (i-Granulosa Cell Tumor) olwakheka emaqanda?

Kungenzeka ukuthi awukaze uzwe ngaleli gama elithi 'Granulosa Cell Tumor'. Empeleni lolu uhlobo olungavamile lwesimila oluvela emaqanda. Kodwa kubaluleke kakhulu ukwazi ngalo, ngoba lungathinta namanye ama-hormone emzimbeni wethu, ikakhulukazi empilweni yabesifazane. Ake sixoxe ngalokhu ngokuningiliziwe.

Kuyini i-Granulosa Cell Tumor?

Kalula nje, lesi yisisu esikhethekile esikhula ema-ovari. Odokotela basibiza ngokuthi ``Sex Cord-Stromal Tumor''. La ma-tumor akhula ezicutshini ezizungeze ama-ovari. La ma-tumor angabangela umzimba ukuthi ukhiqize i-hormone yocansi yabesifazane eningi kakhulu ``(i-Estrogen)''. Sivame ukutholakala sineminyaka engaba ngu-50, kodwa singakhula kunoma yimuphi ubudala.

La maqhubu akheka kuphi?

Lokhu `(Granulosa Cell Tumor)` kukhulela ngqo ngaphakathi kwama-ovari. Njengoba wazi, ama-ovari ayingxenye ebaluleke kakhulu yesistimu yokuzala yabesifazane. Ngaphezu kokukhiqiza amaqanda, ama-ovari akhiqiza nama-hormone amabili okuzala `(Ova)` kanye `(Estrogen)` kanye `(Progesterone)`.

Zivame kangakanani lezi zinto?

Empeleni lezi zibizwa ngokuthi "ama-Granulosa Cell Tumors" futhi azivamile kangako. Zakha cishe u-5% kuphela wazo zonke "ama-Primary Ovarian Tumors". Lelo yiphesenti eliphansi kakhulu.

Ingabe la maqhubu ayingozi noma ayingozi?

Esikhathini esiningi, la maqhubu, abizwa ngokuthi "ama-Granulosa Cell Tumors", abhekwa njengezimo eziyingozi. Kodwa izindaba ezinhle ukuthi avame ukukhula kancane. Yingakho odokotela bekwazi ukuwathola esiteji sokuqala. Khona-ke imiphumela yokwelashwa nayo mihle kakhulu.

Uyini umehluko phakathi kwe-Granulosa Cell Tumor kubantu abadala kanye nakubantu abasha?

Lezi zimila zivame ukubonakala kwabesifazane asebekhulile. Eqinisweni, amacala angu-95% abikwe kwabesifazane asebekhulile abakhule kahle. Kodwa-ke, uma kuvela kumuntu ongaphansi kweminyaka engu-30, sikubiza ngokuthi ``i-Juvenile GCT''. Le ``Juvenile GCT'' ingabuya ngokushesha kunokuba ivele kumuntu omdala. Futhi, uma isakazeke ngaphandle kwesibeletho futhi itholakale kamuva, ingaba yingozi kakhulu.

Kungani lokhu (i-Granulosa Cell Tumor) kuvela? Iyini imbangela?

Odokotela abakakatholi ukuthi yini ngempela ebangela ama-Granulosa Cell Tumors. Kodwa-ke, iningi labantu abanalezi zimila linoguquko ku-gene ebizwa ngokuthi i-FOXL2 gene. Le gene ye-FOXL2 yiyo evame ukusiza amaseli e-granulosa ukuba akhule kahle.

Ziyini izimpawu? Wazi kanjani?

Uma lesi sigaxa sikhona, uphawu oluyinhloko ukwanda kwamazinga e-estrogen emzimbeni.

• Entombazaneni encane, lokhu kungabangela ukuthi ifinyelele ebusheni isencane.
• Abesifazane asebekhulile bangase babe nezimpawu ezifana nalezi:
• Ukopha okungavamile kwesibeletho (AUB) noma ukopha ngemva kokunqamuka kokuya esikhathini.
• Indawo yesisu iyavuvukala futhi ikhule.
• Imijikelezo yokuya esikhathini ayivamile noma iyeke ngokuphelele.
• Ubuhlungu bebele kanye nokuqina kwalo.
• Ngezinye izikhathi, uma iqhubu liqhuma, kungabangela ubuhlungu esiswini.

Yiziphi izinkinga ezingaba khona uma zingelashwa?

Uma lesi `(i-Granulosa Cell Tumor)` singelashwa ngesikhathi, ingozi yokuthola ezinye izinkinga zempilo inganda. Isibonelo:

• I-Endometrial hyperplasia ukuqina okungajwayelekile kodonga lwangaphakathi lwesibeletho.
• Umdlavuza Wesibeletho.
• Umdlavuza webele.
• Ubunzima bokuthola abantwana (Ukungazali).

Ukuthola kanjani lokhu?

Odokotela bavame ukusebenzisa amasu ahlukahlukene okuthwebula izithombe ukuze bathole i-Granulosa Cell Tumor. Kungadingeka ukuthi wenze izivivinyo ezinjengalezi:

• I-CT scan.
• I-MRI.
• Ukuhlolwa kwe-ultrasound okwenziwa ngesitho sangasese sowesifazane (i-Transvaginal ultrasound).

Ngaphezu kwalokho, udokotela wakho angase futhi acele ukuhlolwa kwegazi. Ngokukhethekile, bazofuna okuthile okubizwa ngokuthi ``Ama-Tumor Markers``. ``I-Inhibin`` uhlobo ``I-Tumor Marker`` olukhiqizwa yi-``Granulosa Cell Tumor``. Kungase kudingeke nokuhlolwa kwegazi ukuqinisekisa ukuthi azikho ezinye izimo zezokwelapha.

Iphathwa kanjani?

Ukwelashwa kokuqala kwalesi "Granulosa Cell Tumor" ukuhlinzwa. Udokotela ohlinzayo uzama ukususa isimila esiningi ngangokunokwenzeka ngenkathi egcina izicubu ezinempilo.

Uma ungahleli ukuba nezingane ezengeziwe, noma uma usudlulile eminyakeni yokuzala, udokotela wakho angase akuncome ukuthi kususwe i-oophorectomy (ukususwa kwama-ovari) noma kususwe i-hysterectomy (ukususwa kwesibeletho kanye nama-ovari). Kungadingeka ukuthi kususwe i-oophorectomy ngokuphelele ukuze kususwe i-GCT.

Odokotela bahlukanisa lesi sithi "Granulosa Cell Tumor" ngokuya ngokuthi sitholakala kuphi nokuthi sisakazeke yini, besebenzisa inqubo ebizwa ngokuthi "Staging." Lena yindlela abanquma ngayo ukuthi umdlavuza usakazeke noma cha.

• Isigaba 1 se-GCT yilawo angakasabalali ngale kwama-ovari.
• Isigaba sesi-2 kuya kwesi-4 se-GCT yilawo asakazeke (asakazeke) kwezinye izingxenye zomzimba.

Cabanga ngalokhu: 9 kwabayi-10 balezi GCTs batholakala kuphela esibelethweni. Ukuhlinzwa kuvame ukunconywa kulezi zinhlobo zamathumba, futhi ngezinye izikhathi lokho kuphela kunganele.

Kodwa-ke, kuye ngobukhulu besimila kanye nezici zakho ezingabangela ukuphinda kwaso, kungase kube nezinye izindlela zokwelapha ezingasiza ekuvimbeleni isimila ukuthi singabuyi. Udokotela wakho angase asikisele izinto ezifana nalezi:

• Ukwelashwa ngamakhemikhali.
• Ukwelashwa ngama-hormone.
• Ukwelashwa ngemisebe.

Ingabe ikhona indlela yokuvimbela lokhu (i-Granulosa Cell Tumor) ukuthi kungakhuli?

Akukho siqinisekiso sokuthi uzokwazi ukuvimbela ukuthuthukiswa kwe-Granulosa Cell Tumor. Kodwa-ke, ungasiza ngokwamukela indlela yokuphila enempilo kanye nokunciphisa ingozi yakho yokuthola izifo ezingamahlalakhona :

• Ukugcina isisindo esinempilo esifanele uhlobo lomzimba wakho, ubulili kanye nobudala.
• Ukugwema ukubhema.
• Ukudla ukudla okunomsoco.
• Ukuvivinya umzimba njalo ukuze kuthuthukiswe impilo yenhliziyo nemithambo yegazi.
• Ukunciphisa utshwala kanye ne-caffeine.
• Ukusebenzisa izindlela ezinempilo njengokuthi "Ukuqaphela" noma "Ukuzindla" ukuze ulawule ukucindezeleka.
• Ukulala amahora ayisikhombisa kuya kwayisishiyagalombili ubusuku ngabunye.

Unganciphisa kanjani ingozi yezinkinga?

Uma unezimpawu ezibonisa ukuthi ungase ube ne-GCT, bona udokotela ngokushesha. Uma unesifo sokopha okungajwayelekile, ubuhlungu bebele, noma ukopha ngemva kokunqamuka kokuya esikhathini, qiniseka ukuthi ubona udokotela. I-GCT inemiphumela engcono kakhulu uma yelashwa kusenesikhathi.

Ingabe i-Granulosa Cell Tumor ingelapheka ngokuphelele?

Yebo. Ama-GCT angelapheka ngokuhlinzwa, ikakhulukazi uma esuswa kusenesikhathi.

Kodwa-ke, uma kutholakala ngemuva kokuba sekusakazekele kwezinye izingxenye zomzimba, amathuba okululama aphansi. Ngakho-ke, uma unezimpawu ze-GCT, bona udokotela ngokushesha.

Yini ongayilindela ngemva kokwelashwa?

Ngemva kokususwa kwesigaxa, kuzodingeka ubone udokotela wakho njalo ukuze akulandelele iminyaka eminingana. Lokhu kungenxa yokuthi lezi zigaxa zingabuya ngisho nangemva kweminyaka eminingi. Udokotela wakho uzokwenza okulandelayo ukuhlola ukuthi isigaxa sesibuyile yini:

• Ukuhlolwa kwe-pelvic.
• Ukuhlolwa kwegazi ukuze kubhekwe izimpawu zokuthi umdlavuza ungase ubuye.
• Ukuhlolwa kwezithombe.

Iyini inhloso yokululama?

Umbono we-GCT uncike esigabeni sesifo lapho sitholakala. Uma i-GCT itholakala ngaphambi kokuba isakazeke (isakazeke) kwezinye izingxenye zomzimba, umbono uba ngcono kakhulu.

Yini enye okufanele ngiyibuze udokotela?

Ungabuza nodokotela wakho imibuzo efana nale:

• Yini okungenzeka kakhulu ukuthi iyimbangela yalezi zimpawu?
• Yiziphi izivivinyo okudingeka ngizenze ukuze ngithole ukuthi ngine-`(Granulosa Cell Tumor)`?
• Yiziphi izindlela zokwelapha ezikhona?
• Liyini ithuba lokuthi i-GCT ibuye ngemva kokwelashwa?
• Iyini iphrojekthi yokululama ngemva kokususwa kwe-`(Granulosa Cell Tumor)`?

Okokugcina, izinto ezimbalwa okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, nansi eminye yemicikilisho okufanele uyikhumbule mayelana ne-`(Granulosa Cell Tumor)` esikhulume ngayo:

• Lezi uhlobo lwesimila olungavamile, oluvame ukukhula kancane olwakheka eduze kwama-ovari.
• Lokhu kungabangela ukukhiqizwa ngokweqile kwe-hormone ethi "(i-Estrogen)," okungabangela izimpawu ezifana nokopha okungavamile kanye nomjikelezo wokuya esikhathini ongavamile.
• Ukwelashwa okuyinhloko ukususwa kwesimila ngokuhlinzwa.
• Uma kunengozi yokuthi isimila sibuye, udokotela angase ancome ukwelashwa ngamakhemikhali, ukwelashwa ngamahomoni, noma ukwelashwa ngemisebe.
• Uma i-GCT itholakala kusenesikhathi, amathuba okululama mahle kakhulu. Ngakho-ke uma unezimpawu, bona udokotela ngokushesha okukhulu.

Isimila se - Granulosa cell, umdlavuza wesibeletho, i-estrogen, impilo yabesifazane, izimpawu zomdlavuza, ukuhlinzwa, izinkinga zamahomoni