Ingabe umjikelezo wakho wokuya esikhathini usuvele ungajwayelekile? Noma uzizwa nje uvuvukele, uzizwa unzima esiswini sakho esingezansi? Ngezinye izikhathi sicabanga ukuthi lezi yizinto ezivamile, kodwa namuhla sikhuluma ngesizathu esingase sikhathazeke kancane. Lesi yisimo esibizwa ngokuthi i-Granulosa Cell Tumor (GCT). Ungesabi uma uzwa leli gama, kubaluleke kakhulu ukuqaphela lokhu.
Kalula nje, iyini i-Granulosa Cell Tumor (GCT)?
I-Granulosa Cell Tumor (GCT) uhlobo lwesimila esikhula emaqanda abesifazane. Njengoba wazi, amaqanda ayingxenye ebaluleke kakhulu ohlelweni lwethu lokuzala lwabesifazane. Ngaphezu kokukhiqiza amaqanda, la maqanda akhiqiza nama-hormone amabili abesifazane abizwa ngokuthi i-estrogen ne-progesterone.
Okukhethekile ngalezi zimila ze-GCT ukuthi zikhiqiza inani elikhulu le-hormone i-estrogen . Yingakho kuvela izinguquko nezimpawu ezahlukahlukene emzimbeni. Nakuba lezi zimila zingakhula kunoma yimuphi ubudala, zivame ukubonakala cishe eminyakeni engu-50.
I-GCT yisimo esingavamile kakhulu. Sibangela u-5% kuphela wazo zonke izimila zesibeletho. Kodwa kubalulekile ukuqaphela lokhu ngenxa yempilo yakho.
Ingabe lezi zimila ziyingozi?
Yebo, i-Granulosa Cell Tumor uhlobo lwesimila esivame ukuwela esigabeni esibulalayo . Kodwa into ebaluleke kakhulu okudingeka uyikhumbule lapha ukuthi iningi lala mathumba likhula kancane kakhulu . Ngenxa yalokhu, kunamathuba amaningi okuwathola ezigabeni zokuqala. Uma etholakala kusenesikhathi, imiphumela yokwelashwa nayo mihle kakhulu. Ngakho-ke asikho isidingo sokukhathazeka.
Ingabe ukhona umehluko phakathi kwe-GCTs ekhula kubantu abadala kanye nabantu abasebasha?
Yebo, kunomehluko omncane. Lesi simo sivame ukubonakala kwabesifazane asebekhulile. Ama-95% eziguli ezitholakale zinegciwane angabesifazane asebekhulile abakhule kahle.
Kodwa-ke, uma lesi simila sikhula kumuntu osemusha ongaphansi kweminyaka engama-30, kungaba uhlobo olubizwa ngokuthi i-Juvenile GCT . Ngezinye izikhathi lolu hlobo lwe-Juvenile GCT lungakhula ngokushesha kunohlobo olukhula kubantu abadala, futhi lungase lube maningi amathuba okuthi luphinde lubuye eminyakeni embalwa ngemva kokwelashwa.
Yini ebangela ukuthi kwakheke i-GCT?
Ochwepheshe abasazi kahle ukuthi yini ebangela lokhu, kodwa isikhathi esiningi, la mathumba abangelwa ukuguquka kwezakhi zofuzo okuthiwa i-FOXL2., okungukuthi, kukhona ushintsho olubonakalayo. Umsebenzi oyinhloko walesi sakhi sofuzo ukusiza ukukhula okunempilo kwamaseli e-granulosa. Ngakho-ke uma kukhona ushintsho kulesi sakhi sofuzo, amaseli angakhula ngendlela engavamile futhi akhe izimila ezinjengalezi.
Ingabe nawe unalezi zimpawu?
Uphawu oluyinhloko lwe-GCT ukwanda kwamazinga e-estrogen emzimbeni. Izimpawu ezibangelwa yilokhu zingahluka kuye ngeminyaka yakho.
- Intombazane encane ingabonisa izimpawu zokuthomba isencane.
- Kwabesifazane asebekhulile , izimpawu ezilandelayo zivamile.
| Isibonakaliso | Incazelo |
|---|---|
| Ukopha okungajwayelekile | Ukopha okuphindaphindiwe kwabesifazane asebeqede umjikelezo wabo wokuya esikhathini (ngemuva kokunqamuka kokuya esikhathini) noma ukopha okungavamile kwesibeletho kwabesifazane abasebasha. |
| Ukuqunjelwa kwesisu | Ukuvuvukala noma umuzwa wokuvuvukala esiswini esingezansi. |
| Izinguquko emjikelezweni wokuya esikhathini | Ukuyeka ukuya esikhathini okungajwayelekile noma okuphelele. |
| Ubuhlungu bebele | Ubuhlungu noma ukuqaqamba kwebele. |
| Ubuhlungu besisu esingezansi | Lokhu kuvame ukwenzeka kuphela uma i-cyst iqhuma, okungadala ubuhlungu obungazelelwe nobunzima. |
Yiziphi izinkinga ezingaba khona uma zingelashwa?
Uma lesi simo singelashwa ngesikhathi, ingozi yezinye izinkinga zempilo iyanda njengoba amazinga e-estrogen emzimbeni ehlala ephezulu.
| Inkinga engaba khona | Kalula nje... |
|---|---|
| I-Hyperplasia ye-Endometrial | Ukuqina okungavamile kodonga lwangaphakathi lwesibeletho. |
| Umdlavuza Wesibeletho | Ingozi eyengeziwe yokuthuthukisa amangqamuzana omdlavuza wesibeletho. |
| Umdlavuza Webele | Ingozi yomdlavuza webele nayo inganda kancane. |
| Ukungazali | Umthelela ekhonweni lokuba nezingane. |
Odokotela basithola kanjani lesi sifo?
Uma utshela udokotela wakho ngezimpawu ezingenhla, uzokuhlola bese eyalela ukuhlolwa okuningana ukuqinisekisa isimo.
- Ukuthwebula izithombe: Lokhu kungase kuhilele ukuskena kwe-CT , ukuskena kwe-MRI , noma, ngokuvamile , i-ultrasound ye-transvaginal , okuyi-scan eyenziwa ngesitho sangasese sowesifazane.
- Ukuhlolwa Kwegazi: Lokhu kuhlolwa kuhlola izimpawu ezithile zesimila, njenge -Inhibin, ekhiqizwa yi-GCTs. Kuhlola nezinye izimo.
Yiziphi izindlela zokwelapha?
Ukwelashwa kokuqala nokuyinhloko kwe-GCT ukuhlinzwa.Lapha, udokotela ohlinzayo uzama ukususa isimila esiningi ngangokunokwenzeka ngaphandle kokulimaza izicubu ezinempilo.
Uma usemncane, ungahleli ukuba nezingane, noma usuqedile ukuya esikhathini, udokotela wakho angase akuncome ukuthi uhlinzwe nge-oophorectomy , okuhilela ukususa lonke iqanda eliqukethe isimila. Kwezinye izimo, ukuhlinzwa nge-hysterectomy nakho kungadingeka.
Ukunquma isigaba somdlavuza (ukulinganisa)
Ngemva kokuhlinzwa, "isigaba" sinqunywa ukuze kubonakale ukuthi umdlavuza ususakazeke yini.
- Isigaba 1: Isimila sigcinelwe emaqanda futhi asikasabalali.
- Izigaba 2 kuya ku-4: Umdlavuza ususakazeke (ususakazeke) kwezinye izingxenye zomzimba.
Izindaba ezinhle ukuthi iziguli ezingu-9 kwezingu-10 ze-GCT zitholakala esigabeni soku-1 , lapho umdlavuza utholakala kuphela emaqanda. Ezimweni ezinjalo, ukuhlinzwa kuphela kunganele.
Kuye ngobukhulu besimila kanye nengozi yokuphinda sivele, ezinye izindlela zokwelapha zingase zinconywe ngaphezu kokuhlinzwa.
- Ukwelashwa ngamakhemikhali
- Ukwelashwa ngama-hormone
- Ukwelashwa ngemisebe
Kwenzekani ngemva kokwelashwa?
Ngemva kokususwa kwesimila, kuzodingeka ube ngaphansi kokuqashwa kwezokwelapha isikhathi eside, njengoba lezi zimila zingaphinde zibuye ngisho nangemva kweminyaka eminingi . Ngakho-ke, udokotela wakho uzokuhlola ngezikhathi ezithile ukuqinisekisa ukuthi isimila asikabuyi.
- Ukuhlolwa kwe-pelvic
- Ukuhlolwa kwegazi kwezimpawu zomdlavuza
- Izinto ezifana nokuskena zisetshenziselwa lokhu.
Kungenzeka yini ukululama ngokuphelele kulesi simo?
Yebo, nakanjani. I-Granulosa Cell Tumor ingelapheka ngokuphelele, ikakhulukazi uma itholakale kusenesikhathi futhi isuswe ngokuhlinzwa.
Uma umdlavuza utholakala ngemuva kokuba ususakazekele kwezinye izingxenye zomzimba, amathuba okwelashwa angancipha. Yingakho sincoma ukuthi uma unezimpawu ze-GCT, bona udokotela ngokushesha .
Umlayezo Wokuya Nawe Ekhaya
- I-Granulosa Cell Tumor (GCT) iyisimila esingavamile, esivame ukukhula kancane esikhula emaqanda.
- Lokhu kubangela ukukhiqizwa ngokweqile kwe-hormone i-estrogen, okubangela izimpawu ezifana nokopha okungajwayelekile kanye nokuqunjelwa.
- Uma umuntu omjikelezo wakhe wokuya esikhathini umile ephinda ephuma igazi, noma enezinye izimpawu ezingavamile, ungalibali. Bonana nodokotela ngokushesha.
- Uma itholakale ezigabeni zokuqala, ingelapheka ngokuphelele ngokuhlinzwa.
- Ukuqapha isikhathi eside kwezokwelapha kubaluleke kakhulu, njengoba lezi zimila zingaphinde zivele ngisho nangemva kokwelashwa.
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