Kungenzeka ukuthi uke wabona nendaba yezindaba yakamuva mayelana ne-Human Growth Hormone, noma i-HGH. Ukuzwa ukuthi le hormone ingabangela isifo i-Alzheimer kumele ukuthi kukwenze wesaba futhi wakhathazeka kancane, akunjalo? Lokhu kwesaba kungaba kukhulu nakakhulu uma udokotela ekunike lo muthi we-hormone wena noma ingane yakho. Ngakho ake sixoxe ngalokhu ngokuningiliziwe namuhla, liyini iqiniso kule ndaba, futhi masiqonde ngokucacile ukuthi kufanele sesabe noma cha.
Le ndaba yaqala kanjani?
Le ndaba ivele ngokuzumayo ocwaningweni olwenziwe yiqembu labacwaningi eBrithani ngonyaka ka-2024. Bathole ukuthi kudala, phakathi kuka-1959 no-1989, abantu abaningana abathola uhlobo olukhethekile lwe-HGH olunikezwa izingane ezikhubazekile kamuva baba nesifo i-Alzheimer's.
Kodwa into ebaluleke kakhulu lapha uhlobo lwe-HGH olwalusetshenziswa ngaleso sikhathi. Lubizwa ngokuthi i-cadaveric growth hormone . Kalula nje, lawo ma-hormone ayethathwa emizimbeni yabantu abafileyo, ikakhulukazi e-pituitary gland ebuchosheni. Cabanga ngakho njengokuphatha omunye umuntu ngengxenye yomzimba wakhe.
Cishe ngo-1985, umuntu owayethathe le hormone yakudala waba nesifo sobuchopho esiyingozi esibizwa ngokuthi isifo se-Creutzfeldt-Jakob (CJD) . Yisifo esibangela ukulahlekelwa yinkumbulo okufana ne-Alzheimer's. Ukuhlolwa kwakamuva kwaqinisekisa ukuthi lesi sifo se-CJD sibangelwa ukukhubazeka kwama-hormone athathwe kulabo bantu abashonile. Ngalesi sigameko, i-HGH kubantu abashonile yamiswa ngokuphelele emhlabeni wonke.
Ucwaningo olusha lusanda kuthola ukuthi lapho kuhlolwa ubuchopho babantu abaningana eqenjini elifanayo abashone ngenxa ye-CJD, babune-deposit yeprotheni ebizwa ngokuthi i-beta-amyloid ebuchosheni babo. Lena yiprotheni efanayo efakwa ebuchosheni babantu abanesifo i-Alzheimer's. Abaningana balaba bantu babenezimpawu ze-Alzheimer's besebancane kakhulu, beneminyaka engama-30 nama-40.
Ngakho-ke lolu cwaningo lusikisela ukuthi ukungcola okuthile ku-HGH endala, eneminyaka engamashumi eminyaka ethathwe kubantu abafileyo kungenzeka ukuthi kwaholela ekutheni amaprotheni ahlobene nesifo i-Alzheimer amuncwe emzimbeni.
Ngakho-ke ingabe i-HGH enikezwa namuhla iyingozi kangako?
Nansi into ebaluleke kakhulu okudingeka uyiqonde kahle. Cha. I-HGH enikezwa namuhla ayiyona ingozi kangako.
Sekungamashumi eminyaka odokotela emhlabeni wonke benikeza imithi yokwenziwa i-HGH . Okusho ukuthi, i-hormone ekhiqizwa elabhorethri ngendlela ehlanzekile kakhulu, ephephile, futhi eyenziwe. Ayinazo izicubu zomuntu. Ngakho-ke, awekho amathuba okuthi i-CJD, noma iphrotheni ye-Alzheimer, njengoba ucwaningo oludala lusikisela, ingadluliselwa kusuka komunye umuntu iye komunye.
Ake sibone ngokucacile umehluko phakathi kwalezi zindlela ezimbili.
| Isici | I-HGH endala (i-Cadaveric - ngaphambi kuka-1989) | I-HGH Yesimanje (Eyenziwe - Yamanje) |
|---|---|---|
| Ungayithola kanjani | Kutholakala ezindlala ze-pituitary zabantu asebeshonile. | Kukhiqizwe ngokwenziwa nangokuhlanzekile elabhorethri. |
| Ukuphepha kanye nengozi | Kwakukhona ingozi yokudlulisa amaprotheni ahlobene nezifo ezifana ne-CJD kanye ne-Alzheimer's. | Ngenxa yokuthi ayinazo izicubu zomuntu , akukho nhlobo ingozi yokudluliselwa okunjalo. |
| Ukusetshenziswa kwamanje | Akukaze kusetshenziswe ndawo emhlabeni wonke amashumi eminyaka manje. | Lolu uhlobo olulodwa kuphela lwe-HGH olusetshenziswa njengamanje kudokotela. |
Ake sifunde futhi ngezinguquko zemvelo emazingeni e-HGH.
Kunezifundo eziphakamisa ukuthi amazinga aphezulu ngokwemvelo e-HGH emzimbeni (isib., izimo ezifana ne -acromegaly ) noma amazinga aphansi angaba nemiphumela ethile enkumbulo kamuva empilweni. Kodwa lokho kuhluke ngokuphelele ekuthatheni i-HGH ngesilinganiso esifanele njengokwelashwa ngaphansi kokuqondisa kukadokotela. Eqinisweni, uma umuntu onesifo se-HGH engelashwa kahle, ukwehla kwengqondo kungenzeka.
Ingabe isifo sika-Alzheimer siyathelelana?
Lokhu kuyinkinga nakubantu abaningi. Cha. Isifo i-Alzheimer's asithelelani. Awusitholi lesi sifo ngoba nje unakekele umuntu one-Alzheimer's, ubunaye, usebenzise into ayisebenzisile. Asithelelani njengomkhuhlane.
Okwenzekile kuleso sigameko esidala se-HGH kwaba ukujova izinto eziphilayo ezingcolisiwe emzimbeni. Lokho kuyingqayizivele kakhulu futhi kuyinto engasakwenzeka.
Izici zangempela eziyingozi zokuthuthukisa isifo i-Alzheimer's yilezi:
- Ukuguga: Ingozi iyanda njengoba iminyaka ikhula.
- Umlando womndeni: Ingozi iphezulu uma othile emndenini eke waba nayo.
- Ukulimala okukhulu ekhanda.
- Izimo ezithile zezokwelapha: umfutho wegazi ophakeme, isifo sikashukela, i-cholesterol ephezulu.
- Indlela Yokuphila: Ukudla okungenampilo, ukukhuluphala ngokweqile, ukuntuleka kokuzivivinya umzimba, kanye nokungalali ngokwanele.
Ngakho-ke kufanele ngiyeke ukwelashwa nge-HGH?
Cha, akunjalo neze. Uma wena noma ingane yakho nithola ukwelashwa kwe-HGH ngesincomo sikadokotela, ningesabi futhi niyeke ukwelashwa ngokushesha ngemva kokubona izindaba ezinjengalezi. Ukwenza kanjalo kuzokwenza umonakalo omkhulu kunokuhle.
Kulezi zinsuku, ukwelashwa kwe-HGH kunikezwa ngezizathu zezokwelapha ezicacile. Isibonelo:
- Ukuntuleka kwe-hormone yokukhula
- Ukushoda okubangelwa yizimo zofuzo ezifana ne -Turner syndrome kanye ne-Prader-Willi syndrome .
- Ukulahlekelwa yimisipha okubangelwa ukutheleleka yi-HIV.
- Isifo samathumbu amafushane.
Ukwelashwa nge-HGH kuyindlela yokwelapha ebaluleke kakhulu futhi ephephile kubantu abanalezi zimo. Ngakho-ke, into engcono kakhulu ongayenza ukuxoxa ngokukhululekile nganoma yikuphi ukungabaza noma ukwesaba onakho nodokotela wakho okwelaphayo. Uzokuchazela lokhu ngokuningiliziwe futhi anciphise ukwesaba kwakho.
Uma wena noma ingane yakho ninikezwe ukwelashwa nge-HGH ngudokotela, qiniseka ukuthi nikhuluma nayo ngaphambi kokuyiyeka. I-HGH yokwenziwa esetshenziswa njengamanje ayibeki ingozi ye-Alzheimer's.
Umlayezo Wokuya Nawe Ekhaya
- Muva nje, kube nenkulumo ngohlobo lwe-HGH oluthathwe kubantu asebeshonile olwasetshenziswa emashumini eminyaka edlule (1959-1989). Alusasetshenziswa ndawo.
- I-HGH esetshenziswa njengamanje iyi-hormone ephephile kakhulu ekhiqizwa elabhorethri (eyenziwe). Ayinawo umngcipheko wokudlulisa izifo ezifana ne-Alzheimer's noma i-CJD.
- Isifo i-Alzheimer's akusona isifo esidluliselwa kusuka komunye umuntu kuya komunye empilweni evamile yansuku zonke.
- Uma udokotela wakho ekuncomile ukwelashwa kwe-HGH, qhubeka nakho ngaphandle kokwesaba. Uma ungabaza, qiniseka ukuthi ukhuluma nodokotela wakho ngaphambi kokuyeka ukwelashwa.
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