Kungenzeka ukuthi uke wabona nendaba yezindaba yakamuva mayelana ne-Human Growth Hormone, noma i-HGH. Ukuzwa ukuthi le hormone ingabangela isifo i-Alzheimer kumele ukuthi kukwenze wesaba futhi wakhathazeka kancane, akunjalo? Lokhu kwesaba kungaba kukhulu nakakhulu uma udokotela ekunike lo muthi we-hormone wena noma ingane yakho. Ngakho ake sixoxe ngalokhu ngokuningiliziwe namuhla, liyini iqiniso kule ndaba, futhi masiqonde ngokucacile ukuthi kufanele sesabe noma cha.
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Le ndaba yaqala kanjani?
Le ndaba ivele ngokuzumayo ocwaningweni olwenziwe yiqembu labacwaningi eBrithani ngonyaka ka-2024. Bathole ukuthi kudala, phakathi kuka-1959 no-1989, abantu abaningana abathola uhlobo olukhethekile lwe-HGH olunikezwa izingane ezikhubazekile kamuva baba nesifo i-Alzheimer's.
Kodwa into ebaluleke kakhulu lapha uhlobo lwe-HGH olwalusetshenziswa ngaleso sikhathi. Lubizwa ngokuthi i-cadaveric growth hormone . Kalula nje, lawo ma-hormone ayethathwa emizimbeni yabantu abafileyo, ikakhulukazi e-pituitary gland ebuchosheni. Cabanga ngakho njengokuphatha omunye umuntu ngengxenye yomzimba wakhe.
Cishe ngo-1985, umuntu owayethathe le hormone yakudala waba nesifo sobuchopho esiyingozi esibizwa ngokuthi isifo se-Creutzfeldt-Jakob (CJD) . Yisifo esibangela ukulahlekelwa yinkumbulo okufana ne-Alzheimer's. Ukuhlolwa kwakamuva kwaqinisekisa ukuthi lesi sifo se-CJD sibangelwa ukukhubazeka kwama-hormone athathwe kulabo bantu abashonile. Ngalesi sigameko, i-HGH kubantu abashonile yamiswa ngokuphelele emhlabeni wonke.
Ucwaningo olusha lusanda kuthola ukuthi lapho kuhlolwa ubuchopho babantu abaningana eqenjini elifanayo abashone ngenxa ye-CJD, babune-deposit yeprotheni ebizwa ngokuthi i-beta-amyloid ebuchosheni babo. Lena yiprotheni efanayo efakwa ebuchosheni babantu abanesifo i-Alzheimer's. Abaningana balaba bantu babenezimpawu ze-Alzheimer's besebancane kakhulu, beneminyaka engama-30 nama-40.
Ngakho-ke lolu cwaningo lusikisela ukuthi ukungcola okuthile ku-HGH endala, eneminyaka engamashumi eminyaka ethathwe kubantu abafileyo kungenzeka ukuthi kwaholela ekutheni amaprotheni ahlobene nesifo i-Alzheimer amuncwe emzimbeni.
Ngakho-ke ingabe i-HGH enikezwa namuhla iyingozi kangako?
Nansi into ebaluleke kakhulu okudingeka uyiqonde kahle. Cha. I-HGH enikezwa namuhla ayiyona ingozi kangako.
Sekungamashumi eminyaka odokotela emhlabeni wonke benikeza imithi yokwenziwa i-HGH . Okusho ukuthi, i-hormone ekhiqizwa elabhorethri ngendlela ehlanzekile kakhulu, ephephile, futhi eyenziwe. Ayinazo izicubu zomuntu. Ngakho-ke, awekho amathuba okuthi i-CJD, noma iphrotheni ye-Alzheimer, njengoba ucwaningo oludala lusikisela, ingadluliselwa kusuka komunye umuntu iye komunye.
Ake sibone ngokucacile umehluko phakathi kwalezi zindlela ezimbili.
| Isici | I-HGH endala (i-Cadaveric - ngaphambi kuka-1989) | I-HGH Yesimanje (Eyenziwe - Yamanje) |
|---|---|---|
| Ungayithola kanjani | Kutholakala ezindlala ze-pituitary zabantu asebeshonile. | Kukhiqizwe ngokwenziwa nangokuhlanzekile elabhorethri. |
| Ukuphepha kanye nengozi | Kwakukhona ingozi yokudlulisa amaprotheni ahlobene nezifo ezifana ne-CJD kanye ne-Alzheimer's. | Ngenxa yokuthi ayinazo izicubu zomuntu , akukho nhlobo ingozi yokudluliselwa okunjalo. |
| Ukusetshenziswa kwamanje | Akukaze kusetshenziswe ndawo emhlabeni wonke amashumi eminyaka manje. | Lolu uhlobo olulodwa kuphela lwe-HGH olusetshenziswa njengamanje kudokotela. |
Ake sifunde futhi ngezinguquko zemvelo emazingeni e-HGH.
Kunezifundo eziphakamisa ukuthi amazinga aphezulu ngokwemvelo e-HGH emzimbeni (isib., izimo ezifana ne -acromegaly ) noma amazinga aphansi angaba nemiphumela ethile enkumbulo kamuva empilweni. Kodwa lokho kuhluke ngokuphelele ekuthatheni i-HGH ngesilinganiso esifanele njengokwelashwa ngaphansi kokuqondisa kukadokotela. Eqinisweni, uma umuntu onesifo se-HGH engelashwa kahle, ukwehla kwengqondo kungenzeka.
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Check Availability →Ingabe isifo sika-Alzheimer siyathelelana?
Lokhu kuyinkinga nakubantu abaningi. Cha. Isifo i-Alzheimer's asithelelani. Awusitholi lesi sifo ngoba nje unakekele umuntu one-Alzheimer's, ubunaye, usebenzise into ayisebenzisile. Asithelelani njengomkhuhlane.
Okwenzekile kuleso sigameko esidala se-HGH kwaba ukujova izinto eziphilayo ezingcolisiwe emzimbeni. Lokho kuyingqayizivele kakhulu futhi kuyinto engasakwenzeka.
Izici zangempela eziyingozi zokuthuthukisa isifo i-Alzheimer's yilezi:
- Ukuguga: Ingozi iyanda njengoba iminyaka ikhula.
- Umlando womndeni: Ingozi iphezulu uma othile emndenini eke waba nayo.
- Ukulimala okukhulu ekhanda.
- Izimo ezithile zezokwelapha: umfutho wegazi ophakeme, isifo sikashukela, i-cholesterol ephezulu.
- Indlela Yokuphila: Ukudla okungenampilo, ukukhuluphala ngokweqile, ukuntuleka kokuzivivinya umzimba, kanye nokungalali ngokwanele.
Ngakho-ke kufanele ngiyeke ukwelashwa nge-HGH?
Cha, akunjalo neze. Uma wena noma ingane yakho nithola ukwelashwa kwe-HGH ngesincomo sikadokotela, ningesabi futhi niyeke ukwelashwa ngokushesha ngemva kokubona izindaba ezinjengalezi. Ukwenza kanjalo kuzokwenza umonakalo omkhulu kunokuhle.
Kulezi zinsuku, ukwelashwa kwe-HGH kunikezwa ngezizathu zezokwelapha ezicacile. Isibonelo:
- Ukuntuleka kwe-hormone yokukhula
- Ukushoda okubangelwa yizimo zofuzo ezifana ne -Turner syndrome kanye ne-Prader-Willi syndrome .
- Ukulahlekelwa yimisipha okubangelwa ukutheleleka yi-HIV.
- Isifo samathumbu amafushane.
Ukwelashwa nge-HGH kuyindlela yokwelapha ebaluleke kakhulu futhi ephephile kubantu abanalezi zimo. Ngakho-ke, into engcono kakhulu ongayenza ukuxoxa ngokukhululekile nganoma yikuphi ukungabaza noma ukwesaba onakho nodokotela wakho okwelaphayo. Uzokuchazela lokhu ngokuningiliziwe futhi anciphise ukwesaba kwakho.
Uma wena noma ingane yakho ninikezwe ukwelashwa nge-HGH ngudokotela, qiniseka ukuthi nikhuluma nayo ngaphambi kokuyiyeka. I-HGH yokwenziwa esetshenziswa njengamanje ayibeki ingozi ye-Alzheimer's.
Umlayezo Wokuya Nawe Ekhaya
- Muva nje, kube nenkulumo ngohlobo lwe-HGH oluthathwe kubantu asebeshonile olwasetshenziswa emashumini eminyaka edlule (1959-1989). Alusasetshenziswa ndawo.
- I-HGH esetshenziswa njengamanje iyi-hormone ephephile kakhulu ekhiqizwa elabhorethri (eyenziwe). Ayinawo umngcipheko wokudlulisa izifo ezifana ne-Alzheimer's noma i-CJD.
- Isifo i-Alzheimer's akusona isifo esidluliselwa kusuka komunye umuntu kuya komunye empilweni evamile yansuku zonke.
- Uma udokotela wakho ekuncomile ukwelashwa kwe-HGH, qhubeka nakho ngaphandle kokwesaba. Uma ungabaza, qiniseka ukuthi ukhuluma nodokotela wakho ngaphambi kokuyeka ukwelashwa.
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