Uke wezwa ngalo mdlavuza ongavamile wendlala yakho yegilo? (Hürthle Cell Carcinoma) – Ake sixoxe ngokuningiliziwe!

Wake wazizwa uneqhubu ngaphambili kwentamo yakho, ngaphansi nje kwethambo lakho lentamo? Noma uzizwa izinto ezifana nokushintsha kwezwi lakho, ubunzima bokugwinya, noma ukuphelelwa umoya? Nakuba singase singazinaki kakhulu lezi zinto, zingaba izimpawu zohlobo lomdlavuza olungavamile kodwa oluvame kakhulu . Namuhla sizokhuluma ngomdlavuza ongavamile kodwa ophathelene nomdlavuza okhula endlaleni yethu ye-thyroid. Lowo yi-Hürthle Cell Carcinoma.

Kuyini i-Hürthle Cell Carcinoma?

Kalula nje, lolu uhlobo lomdlavuza olungavamile nolukhula ngokushesha oluvela endlaleni ye-thyroid . Uyazi, i-thyroid iyindlala encane, efana novemvane engaphambili entanyeni yethu. Ama-hormone ayikhiphayo asiza ukulawula imisebenzi eminingi ebalulekile emzimbeni wethu, ikakhulukazi i-metabolism.

Ngakho-ke, lapho kuvela le Hürthle Cell Carcinoma, izinto ezifana namaqhubu e-thyroid zingakheka. Lapho la maqhubu ekhula, angenza kube nzima ngathi ukukhuluma noma ngisho nokuphefumula. Uma engelashwa kahle, lo mdlavuza ungasakazekela kwezinye izingxenye zomzimba, njenge-lymph node, amaphaphu, namathambo . Odokotela bavame ukwelapha lo mdlavuza ngokwenza ukuhlinzwa ukuze kususwe yonke noma ingxenye ye-thyroid gland.

Lesi simo sithinta kanjani umzimba wami?

Cabanga nje, abanye abantu bangase bangaboni noma yiziphi izinguquko emizimbeni yabo ezigabeni zokuqala ngisho noma bene-Hürthle Cell Carcinoma. Ngezinye izikhathi itholakala ngengozi ngesikhathi sokuhlolwa kwesinye isifo.

Kodwa uma izimpawu ziqala ukubonakala, zingase ziqale zibonakale njengezigaxa ezincane ngaphambili kwentamo, lapho kukhona khona indlala yegilo. Njengoba lezi zigaxa zikhula, zingacindezela umphimbo wethu, zenze kube nzima ukugwinya ukudla, kanye nomphimbo wethu, okwenza kube nzima ukuphefumula. Futhi, uma lezi zigaxa zicindezela izintambo zethu zezwi, kungase kube noshintsho ezwini lethu. Kungase kuzwakale sengathi izwi lakho liyasha uma unomkhuhlane .

Ingabe Ama-tumor e-Hürthle Cell Ahlala Engumdlavuza?

Nasi iphuzu elibalulekile. Amathumba eseli le-Hürthle angaba angewona umdlavuza noma abe umdlavuza . Ngokumangazayo, izimpawu zazo zombili izinhlobo zingafana kakhulu. Ngakho-ke, ngezinye izikhathi kunzima ngodokotela ukusho ngokuqinisekile ukuthi isimila sinomdlavuza noma cha ngokusibuka nje. Ukuze baqiniseke, kumele bahlole amaseli avela ku-tumor ngaphansi kwe-microscope .

Ubani onamathuba amaningi okuthola lesi sifo?

Empeleni, noma ubani angaba ne-Hürthle Cell Carcinoma. Kodwa-ke,Kuvame kakhulu kubantu abaneminyaka engaphezu kwengu-55. Kuthiwa futhi abesifazane banamathuba amaningi okuthola lesi sifo kunabesilisa.

Ingabe lesi yisimo esivamile?

Cha, lesi akusona isimo esivamile kakhulu . Ngokwesilinganiso, cishe abantu abayi-14 kwabayi-100,000 kubikwa ukuthi banesifo somdlavuza we-thyroid njalo ngonyaka. Phakathi kwazo zonke lezi zimo zomdlavuza we-thyroid, le Hürthle Cell Carcinoma itholakala ngephesenti elincane kakhulu, cishe u-3% . Lokho kusho ukuthi ayivamile.

Ziyini izimpawu ze-Hürthle Cell Carcinoma?

Ngokuvamile, abantu abanalesi simo ababi nezimpawu kuze kube yilapho umdlavuza usukhule ngokwanele ukuthi uthinte ezinye izingxenye zomzimba . Isibonelo, ushintsho lwezwi luyenzeka lapho isimila sicindezela izintambo zezwi. Ezinye izimpawu zingafaka:

• Ubunzima bokuphefumula noma ukugwinya (dysphagia) . Kungase kuzwakale sengathi kukhona okubambeke emphinjeni wakho.
• Ukuzizwa sengathi umphimbo wakho uvalekile.
• Iqhubu elibuhlungu ngaphambili kwentamo, ngaphansi kwe-apula lika-Adam.
• Ama-lymph node avuvukele.
• Ukuzizwa ukhathele ngaso sonke isikhathi (Ukukhathala).
• Ukuba mncane ngaphandle kwenhloso noma isizathu .

Yini ebangela lo mdlavuza?

Abacwaningi bezokwelapha abakakwazi ukuthola imbangela eqondile yalesi simo. Kodwa-ke, bathole ezinye izinto eziyingozi ezandisa ingozi yokuthola lesi sifo. Lezi zifaka:

• Ukuba nomlando womndeni womdlavuza we-thyroid : Lokhu kusho ukuthi umama wakho, ubaba wakho, noma izingane zakini bake baba nomdlavuza we-thyroid.
• Ukuntuleka kwe-iodine isikhathi eside : I-iodine iyiminerali ebalulekile edingwa yimizimba yethu ukuze yenze ama-hormone e-thyroid. Siyithola ekudleni esikudlayo.
• Ukuchayeka emisebeni : Odokotela abaningi bakholelwa ukuthi ukuchayeka emisebeni ye-X noma ukwelashwa ngemisebe ezintweni ezinjengomdlavuza kwandisa nengozi yokuthola i-Hürthle Cell Carcinoma.

Odokotela basithola kanjani lesi sifo?

Odokotela baxilonga lesi simo ngokukuhlola kuqala, babuze ngezimpawu zakho, umlando wakho wezokwelapha, kanye nomlando wezokwelapha womndeni wakho. Bangase benze izivivinyo ezifana nalezi:

• Ukuhlolwa kwegazi : Indlala yegilo enempilo ikhiqiza iphrotheni ebizwa ngokuthi i-thyroglobulin. Odokotela bazohlola izinga lale thyroglobulin egazini lakho. Uma leli zinga liphezulu, kungaba uphawu lwe-Hürthle Cell Carcinoma.
• Ukuskena kokungenisa i-thyroid: Lokhu kuhlolwa kusetshenziselwa ukuhlola amangqamuzana omdlavuza endlaleni yakho yegilo. Kulesi sivivinyo, inani elincane le-iodine enemisebe lifakwa egazini lakho. Le iodine iqoqana ezicutshini zomdlavuza endlaleni yakho yegilo. Ngemuva kwalokho, kwenziwa i-positron emission tomography scan (i-PET scan) ukuthola izindawo zamangqamuzana omdlavuza.
• I-Laryngoscopy : Lokhu kuhlolwa kuvumela odokotela ukuthi bahlole izintambo zakho zezwi.
• Ukufuthwa kwenaliti encane (i-FNA) : Kule nqubo, udokotela usebenzisa inaliti encane kakhulu, ukuze asuse isampula yezicubu endlaleni yakho ye-thyroid. Izicubu zibe sezihlolwa ngaphansi kwe-microscope ukuze kuhlolwe izimpawu zomdlavuza. Lokhu ngezinye izikhathi kubizwa ngokuthi i-needle biopsy .
• Ukususwa kwe-Lobectomy : Ngezinye izikhathi, imiphumela yokuhlolwa kwe-FNA ayanele ukuba odokotela bafinyelele esiphethweni esiqondile. Uma kunjalo, bazokwenza ukuhlinzwa ukuze basuse ingxenye ye-thyroid abacabanga ukuthi inomdlavuza bese beyihlola.
• I-CT scan : Uma ukuhlolwa kuqinisekisa ukuthi une-Hürthle Cell Carcinoma, odokotela bazokwenza ezinye izivivinyo zezithombe, njenge-CT scan, ukuze babone ukuthi umdlavuza ususakazekele kwezinye izindawo.

Ingabe zikhona izigaba ze-Hürthle Cell Carcinoma?

Yebo, impela. Odokotela basebenzisa lezi zinhlelo zokulinganisa umdlavuza ukuhlela ukwelashwa komdlavuza. Basebenzisa uhlelo lokulinganisa i-TNM ukuhlukanisa i-Hürthle Cell Carcinoma. (U-T umele i-Tumor. U-N umele i-Lymph Node Involvement. U-M umele i-Metastasis.) Kunezigaba zalo mdlavuza kusukela ku-I (eyodwa) kuya ku-IV (ezine).

Odokotela baphinde bacabangele iminyaka yesiguli lapho benquma lezi zigaba. Abantu abatholakale benalesi sifo beneminyaka engu-55 noma ngaphansi, kungakhathaliseki ukuthi singakanani isimila, uma sithinte ama-lymph node, futhi uma singasakazekelanga ezindaweni ezikude, bahlukaniswa njengesigaba I (esokuqala). Kodwa-ke, uma isimila sisakazekele kuma-lymph node akude noma kwezinye izitho zomzimba, abantu abaneminyaka engu-55 noma ngaphansi bahlukaniswa njengesigaba II (esibili).

Kalula nje:

Usayizi wesimila (T - Isimila)

Lokhu kukutshela ukuthi umdlavuza mkhulu kangakanani nokuthi ngabe usakazeke ngale kwendlala yegilo. Lokhu kuyahlukahluka kusukela ezimilaneni ezincane (isb., ezingaphansi kwamasentimitha amabili - `TI`) kuya ezimilaneni ezinkulu (`TIVa`, `TIVb`) ezisakazeke ezicutshini eziseduze entanyeni, ku-trachea, noma ku-esophagus.

Umphumela kuma-lymph node (N - Lymph Node)

Lokhu kubheka ukuthi umdlavuza ususakazeke yini kuma-lymph node aseduze (`N0` - awasakazekanga,`NI` - usakazeke). Uma ususakazeke, kubheka nokuthi usephakathi nentamo (`NIa`) noma emaceleni (`NIb`).

Ukusabalala komdlavuza (M - Metastasis)

Lokhu kukutshela ukuthi umdlavuza ususakazeke ngale kwendlala yegilo kanye nama-lymph node aseduze yini ezithweni ezikude emzimbeni (isib. amaphaphu, amathambo) . (`M0` - akukho ukusabalala okukude,` MI` - ukusabalala okukude).

Udokotela usebenzisa lolu lwazi "(TNM)" ukuze anqume isigaba sokugcina somdlavuza wakho (Isigaba I, II, III, noma IV). Lokhu kubaluleke kakhulu ekuhleleni ukwelashwa.

Odokotela bakuphatha kanjani lokhu?

Ukwelashwa okuyinhloko nokuvame kakhulu kwalesi simo ukuhlinzwa . Kuye ngesimo sakho, odokotela abahlinzayo bangasusa yonke noma ingxenye yendlala yakho yegilo. Bangasusa nama-lymph node lapho umdlavuza ususakazeke khona. Lokhu kuhlinzwa kwegilo yegilo kungasusa umdlavuza ngokuphelele.

Ngemva kokuhlinzwa, unganikezwa imithi yokuvimba i-thyroid gland yakho ekukhiqizeni ama-hormone ukunciphisa amathuba okuba umdlavuza uphinde ubuye . Ngaphezu kwalokho, kunezinye izindlela zokwelapha, ezifana nalezi:

• Ukwelashwa ngama-hormone : Lokhu kubhubhisa amangqamuzana omdlavuza noma kuwavimbele ekukhuleni kwawo.
• Ukwelashwa nge-iodine enomsebe : Lokhu kwelashwa kubhubhisa amangqamuzana omdlavuza we-thyroid.

Ingabe i-Hürthle Cell Carcinoma ingelapheka ngokuphelele?

Yebo, lesi yisimo esingelapheka . Ukuhlinzwa kokususa yonke noma ingxenye yendlala yegilo kuzoqeda umdlavuza. Kodwa-ke, uma wenza lokhu kuhlinzwa, kuzodingeka uthathe imithi impilo yakho yonke ukuze wenze ama-hormone egilo anele umzimba wakho.

Ungayinciphisa kanjani ingozi yokuthola lesi sifo?

Ayikho indlela eqondile yokunciphisa ingozi yakho yokuthola lesi simo. Abanye abantu bathola lesi simo ngoba umndeni wabo unomlando womdlavuza we-thyroid. Uma unalesi simo, kungcono ukukhuluma nodokotela wakho ngezimpawu ezingaba yizimpawu ze-Hürthle Cell Carcinoma.

Lingakanani izinga lokusinda kulesi sifo?

Ucwaningo lwamuva nje lubonise ukuthi abantu abangu-95% abanalesi simo basaphila eminyakeni emihlanu ngemva kokuxilongwa . Futhi ucwaningo olufanayo lubonise ukuthi abangu-93% basaphila eminyakeni eyishumi kamuva . Lokho kuyaduduza ngempela, akunjalo?

Ngizinakekela kanjani? / Kwenzekani ngemva kokwelashwa?

Kuye ngokwelashwa kwakho, kungadingeka ukuthi uthathe imithi yokushintsha ama-hormone e-thyroid impilo yakho yonke . Futhi, i-Hürthle Cell Carcinoma ingabuya ngezinye izikhathi. Ngakho-ke, buza udokotela wakho ukuthi yiziphi izimpawu ezingase zibonise ukuphinda kwesifo .

I-Hürthle Cell Carcinoma uhlobo olungavamile lomdlavuza we-thyroid. Uma unezimpawu, udokotela wakho kungadingeka ukuthi ahlinze i-thyroid ukuqinisekisa ukuthi unalesi simo. Ezimweni eziningi, ukuhlinzwa ukuze kutholakale lesi simo kuzoxazulula inkinga . Kodwa-ke, ukuhlinzwa kukodwa ngeke kuxazulule zonke izinkinga ezibangelwa yi-Hürthle Cell Carcinoma.

Abantu abake bahlinzwa i-thyroid kuzodingeka bathathe imithi yama-hormone impilo yabo yonke. Futhi, lo mdlavuza ungabuya ngemva kokwelashwa. Uma unalesi simo, sicela ukhumbule ukuthi odokotela bakho bahlala bekhona ukukusiza nokukusekela , ikakhulukazi uma lesi sifo siphinde sibuye.

Izinto ezibaluleke kakhulu okufanele uzikhumbule kulesi sihloko

Kulungile, ake sifingqe ezinye zezinto ezibaluleke kakhulu okudingeka uzikhumbule kulokho esikhulume ngakho:

• I-Hürthle Cell Carcinoma uhlobo lomdlavuza we-thyroid olungavamile, kodwa olunolaka kancane .
• Kubalulekile ukufuna iseluleko sezokwelapha uma unezimpawu ezifana nezigaxa zentamo, izinguquko zezwi, noma ubunzima bokugwinya.
• Kudingeka i-biopsy ukuze wazi ngokuqinisekile ukuthi lokhu kungumdlavuza noma cha.
• Ukwelashwa okuyinhloko ukususwa kwendlala yegilo ngokuhlinzwa .
• Ngemva kokuhlinzwa, kungase kudingeke ukuthi uphuze amaphilisi e-thyroid hormone impilo yakho yonke .
• Kukhona ithuba lokuthi umdlavuza uzophinde ubuye, ngakho-ke udinga ukuqaphela lokho futhi .
• Ithimba lakho lezokwelapha lihlala likulungele ukukusekela .

Ngiyethemba ukuthi lolu lwazi luzokusiza. Uma unemibuzo noma ukukhathazeka, sicela ungangabazi ukukhuluma nodokotela wakho.

I- Hürthle Cell Carcinoma, Umdlavuza We-Thyroid, Izimila Zentamo, Ukuhlinzwa Kwe-Thyroid, Izimpawu Zomdlavuza, Ukwelashwa Komdlavuza, I-Hürthle Cell Carcinoma