Ingabe uzizwa ubuhlungu? Ingabe izitho zakho zomzimba ziyaba ndikindiki? Lokhu kungaba yi-Inclusion Body Myositis (IBM)!

Ingabe ngezinye izikhathi uzizwa sengathi unenkinga yokubamba izinto, ukuchofoza inkinobho, noma ngisho nokuhamba? Ungase ucabange, "O, lokhu kuyinto eyenzekayo uma ukhula." Kodwa ngezinye izikhathi, lezi zinto azilula kangako. Namuhla, sizokhuluma ngesimo esingavamile kodwa esibaluleke kakhulu okufanele usiqaphele. Lokho kubizwa ngokuthi 'Inclusion Body Myositis', okwaziwa nangokuthi '(IBM)' ngamafuphi.

Kuyini i-'Inclusion Body Myositis (IBM)'? Ake sikuqonde kalula!

Kalula nje, i-'Inclusion Body Myositis' yisimo esenza imisipha yakho ibe buthaka kancane kancane, kodwa asibangeli ubuhlungu obukhulu. Ngokuvamile siqala ngemva kweminyaka engu-50. Cabanga ngakho, ungase ube nobunzima 'bokuncinza' into encane, ube nobunzima 'bokubamba' into ethile, noma uze ukhubeke futhi uwe uma uhamba nje. Lezi yizimpawu zokuqala ongase uzibone.

Lesi simo, esibizwa ngokuthi 'i-IBM', sikhula kancane kancane eminyakeni eminingi. Akusona isimo esisongela ukuphila. Lokhu kusho ukuthi ngeke sikubulale. Kodwa-ke, ngokuhamba kwesikhathi, singenza kube nzima ukwenza imisebenzi yansuku zonke, okungaholela ekukhubazekeni okuthile. Ngezinye izikhathi, uhlangothi olulodwa lomzimba wakho luthinteka kakhulu. Cishe ingxenye yabantu abanalesi simo bangase babe 'nobunzima bokugwinya'.

Ngeshwa, alikho ikhambi le-IBM okwamanje. Kodwa ungakhathazeki! Ukwelashwa ngokomzimba kungakusiza ukuthi ugcine amandla emisipha yakho isikhathi eside ngangokunokwenzeka.

Sivame kangakanani lesi simo 'se-IBM'?

I-Inclusion Body Myositis yisimo esiseqenjini lezifo ezibuthakathaka imisipha ezibizwa ngokuthi i-myopathies. I-Myopathies yizifo ezihlasela futhi zenze buthaka imisipha yakho. Ucwaningo lubonisa ukuthi i-IBM ithinta abantu abadala abaphakathi kuka-5 no-9 kwabayisigidi. Futhi ivame kakhulu ngokuphindwe kathathu kwabesilisa kunabesifazane (3:1).

Yiziphi izimpawu ze-'Inclusion Body Myositis (IBM)'? Ake sithole ukuthi ziyini ngempela!

Ubuthakathaka bemisipha obubangelwa yi-IBM buqala kancane kakhulu. Buvame ukuqala ezithweni. Ungase uqale uqaphele ubuthakathaka emilenzeni, emathangeni, noma ezandleni, ezihlakaleni, noma eminweni. Cabanga ngalokhu: abanye abantu banenkinga yokufaka izinkinobho zehembe, noma amapeni abo awabhali kahle. Abanye banenkinga yokukhuphuka izitebhisi, noma bayakhubeka bawe besahamba nje.

Njengoba izimpawu ziba zimbi kancane kancane, ungase ubone izinto ezifana nalezi:

• Imisipha ezingalweni, emilenzeni, emahlombe, endaweni yesinqe, ezintendeni zezandla, naseminweni iba buthakathaka kancane kancane. Cabanga nje, awukwazi ukuphakamisa izinto owawukwazi ukuziphakamisa kalula, futhi unenkinga yokuvuka esihlalweni.
• Ubuthakathaka bemisipha entanyeni noma emqaleni. Lokhu kungenza kube nzima ukubamba ikhanda liqonde, kwenze kube nzima ukugwinya ukudla, futhi kungabangela nokuba ukudla kubhajwe.
• Ukuwohloka kwemisipha kubonakala kahle. Lokhu kusho ukuthi imisipha isinciphile futhi iba mncane kakhulu.
• Ubuhlungu bemisipha obuncane, obuvame ukwenzeka (`myalgia`). Kodwa-ke, lobu buhlungu abukho kuwo wonke umuntu, futhi noma ngabe bukhona, abububi kakhulu.

Isibonelo, ake sithi unomngane ogama lakhe linguSunil. Usengakwazi ukubamba indebe yakhe yetiye kahle isikhathi esithile manje, ilokhu isuka esandleni sakhe. Lapho eya kofunda iphephandaba, isandla sakhe sizwakala sengathi siyathuthumela. Ekuqaleni, wayecabanga ukuthi ukukhathala nje. Kodwa kamuva, waqaphela ukuthi lokhu kungaba uphawu lokuqala lwe-'IBM'.

Kungani kwenzeka lokhu `Inclusion Body Myositis (IBM)`? Iyini imbangela?

Eqinisweni, lesi simo esibizwa ngokuthi 'i-Inclusion Body Myositis' asisona i-idiopathic. Okusho ukuthi, kubonakala sengathi senzeka ngaphandle kwesizathu esithile. Njengezinye izinhlobo ze-'myositis', kulokhu, ukuvuvukala kwesikhathi eside emisipheni ('ukuvuvukala okungapheli') kuyimbangela eyinhloko yobuthakathaka bemisipha. Kodwa-ke, abacwaningi abasazi kahle ukuthi kungani lokhu kuvuvukala kwenzeka. Basola ukuthi kungenzeka ukuthi kungenxa yenkinga ngohlelo lokuzivikela komzimba ('isifo sokuzivikela komzimba') . Okusho ukuthi, amangqamuzana avikela umzimba wethu ahlasela ngephutha amangqamuzana ethu emisipha.

`Imizimba yokufakwa` ihlobene futhi ne-`IBM`. Lezi yizinqwaba zamaprotheni ezingavamile ezifakwa ngaphakathi kwamaseli emisipha. Zingabangelwa ukutheleleka ngegciwane, umonakalo wamangqamuzana, noma ukuguquka kwezakhi zofuzo . `Le mizimba yokufakwa` iyabonakala nasezifweni eziwohlokayo zemizwa njenge-`ALS`. Zingaphazamisa ukusebenza okuvamile kwamaseli.

Umehluko phakathi kwe-'Inclusion Body Myopathy' kanye ne-'Inclusion Body Myositis'

Ngezinye izikhathi i-'Inclusion Body Myositis' ibizwa nangokuthi i-'sporadic inclusion body myositis (sIBM)'. I-'Sporadic' isho ukuthi yenzeka ngokungahleliwe, noma ngaphandle kwesizathu esithile. Lokhu kwenzelwa ukuhlukanisa nezimo ezifanayo ezizuzwa njengefa. Lezo ezizuzwa njengefa zibizwa ngokuthi i-'hereditary inclusion body myopathies (hIMB)'. Uma sithi 'inclusion body myopathies', zombili lezi zinhlobo zingezakho. Manje sikhuluma nge-'sIBM' eyenzeka ngokungahleliwe.

I-'Inclusion Body Myositis' ihlolwa kanjani? Yiziphi izivivinyo ezenziwayo?

Ukuze athole ukuthi une-IBM, udokotela uzoqala akubuze ngezimpawu zakho futhi ahlole imisipha yakho. Izimpawu ze-inclusion body myositis zingafana nezezinye izimo, njenge-polymyositis kanye ne-myasthenia gravis. Udokotela wakho uzofuna izinto ezithile ezifana nalezi:

• Yimiphi imisipha ethintekayo? (isib., eminweni noma emathangeni?)
• Ingabe uhlangothi olulodwa kuphela lomzimba oluthinteke kakhulu?
• Ingabe ukuwohloka kwemisipha kubonakala kahle?
• Wawuneminyaka emingaki lapho izimpawu ziqala? (Ngokuvamile ngemva kweminyaka engu-50)

Ngemuva kwalokho, kungase kwenziwe izivivinyo eziningana ukuze "kukhishwe ezinye izimo", njenge:

• Ukuhlolwa kwe-Creatine Kinase (CK): Lokhu kulinganisa izinga le-enzyme ekhethekile egazini. Leli zinga le-'CK' linganda uma kukhona umonakalo emisipheni.
• Ukuhlolwa kwegazi kwamagciwane kanye nezifo ezahlukahlukene zokuzivikela komzimba.
• I-Electromyogram (EMG): Lokhu kulinganisa umsebenzi kagesi emisipheni yakho. Kwenziwa ngokufaka izinaliti ezincane emisipheni.
• Ucwaningo Lokuqhutshwa Kwezinzwa (NCS): Lokhu kulinganisa isivinini lapho umfutho kagesi uhamba khona ngemizwa (imizwa yokunyakaza) elawula imisipha yakho.

Ukuhlolwa kwe-biopsy yemisipha

Indlela engcono kakhulu yokuqinisekisa ukuthi une-inclusion-body myositis ukuthatha ingxenye encane yezicubu (i-biopsy) emisipheni ethintekile. Udokotela wezifo uzobheka le sampula yezicubu ngaphansi kwe-microscope. Uma une-IBM, uzokwazi ukubona imizimba ye-inclusion (ama-protein clumps angajwayelekile, ama-bubble, noma ama-vacuoles) kusampula.

Ingabe kukhona ukwelashwa okuphumelelayo kwe-'Inclusion Body Myositis'?

Ngeshwa, ayikho indlela yokwelapha ephumelelayo ye-inclusive body myositis. Ngokungafani nezinye izimo zokuvuvukala kanye nezifo ezizimele, ayiphenduli kuma-corticosteroids noma emithini yokucindezela amasosha omzimba.

Kodwa ungalilahli ithemba! Ukwelashwa ngokomzimba kanye nokuzivocavoca njalo kubalulekile ukuze ugcine amandla emisipha yakho isikhathi eside ngangokunokwenzeka. Ukuzivocavoca kungasiza ekuvimbeleni ubuthakathaka bemisipha obengeziwe.

Njengoba lesi sifo siqhubeka futhi kuba nzima ukwenza imisebenzi yansuku zonke, kungadingeka ufunde izindlela ezintsha zokwenza izinto. Yilapho ukwelashwa ngokomsebenzi kungasiza khona. Isibonelo, bangakufundisa ukuthi ungasebenzisa kanjani amadivayisi ahlukahlukene ukukusiza ukuthi ugqoke, udle, futhi ubhale. Abanye abantu kungadingeka futhi bafunde ukuthi ungasebenzisa kanjani isihlalo sabakhubazekile. Uma unenkinga yokugwinya, i-Speech-Language Pathologist (SLP) ingakusiza. Bangakufundisa ukuthi ungagwinya kanjani ngokuphephile futhi wenze izivivinyo zokugwinya.

Uma ngine-'Inclusion Body Myositis', yini okufanele ngiyilindele?

Uma une-'IBM', izokhula kancane kancane. Njengoba ngishilo ngaphambili,Lokhu ngeke kuthinte isikhathi sakho sokuphila. Kodwa-ke, kungase kube nomthelela ezingeni lempilo yakho. Kungase kudingeke uthembele kwabanye noma ufunde izindlela ezintsha zokwenza izinto. Iningi labantu alilahlekelwa ikhono labo lokuhamba ngokuphelele, kodwa abanye bangadinga isihlalo sabakhubazekile ngemva kweminyaka eyi-10-15.

Ngingazinakekela kanjani ngenkathi ngiphila ne-inclusive-body myositis?

Kuzodingeka uphile `ne-Inclusion body myositis` isikhathi eside, futhi kungaba yinselele kancane ngokuhamba kwesikhathi. Indlela engcono kakhulu yokubhekana nalokhu ukwenza uhlelo lwesikhathi eside lokunakekela impilo yakho engokomzimba nengokwengqondo. Lokho kusho ukuqhubeka nokuzijwayeza imikhuba emincane ekusiza ukuthi uhlale uphilile. Isibonelo:

• Qhubeka nohlelo lwakho lokuzivocavoca. Ungase ube sekwelashweni ngokomzimba, noma kungenzeka ukuthi usushintshele ohlelweni lokuzivocavoca ekhaya. Ukuqhubeka nalo mkhuba kuzosiza ukugcina imisipha yakho iqinile ngangokunokwenzeka.
• Landela "indlela yokuphila yempilo enhle." Uma udla kahle, ulala kahle, ulawula ukucindezeleka, futhi ulondoloza ubuhlobo bakho obubalulekile, uzozizwa ungcono kakhulu.
• Joyina amaqembu okusekelana. Ungathola amandla amaningi engqondo kanye nezeluleko ezisebenzayo kwabanye abantu abake badlula noma abadlula kuleso simo obhekene naso. Kuhle futhi ukuzizwa sengathi "Angingedwa engidlula kulesi simo."
• Bheka izindlela zokuzivumelanisa nezimo ekhaya nasemsebenzini. Kunezinsiza eziningi zokuhamba kanye namadivayisi okusiza angasiza abantu abakhubazekile ngokomzimba ukwenza imisebenzi yansuku zonke ibe lula.
• Bona udokotela wakho njalo. Hlala uthintana nodokotela wakho. Tshela udokotela wakho ngokushesha uma ubona noma yiziphi izimpawu ezintsha, njengobunzima bokugwinya, noma uma uphawu olukhona luba lubi kakhulu.
• Hlola izivivinyo zemitholampilo. Abacwaningi bahlala befuna izindlela ezintsha zokwelapha ezingasiza nge-inclusive body myositis. Ungahlanganyela futhi kulezi zivivinyo.

Lesi simo, esibizwa ngokuthi 'i-Inclusion body myositis', sivame ukwenzeka phakathi neminyaka yobudala, lapho kungekho themba. Akekho olindele ukuthi avele ngokuzumayo abe nesifo esingelapheki nesiqhubekayo. Kungaba nzima kancane ukubhekana naso nokuchazela labo abakukhathalelayo, ikakhulukazi uma bengakaze bezwe ngalesi sifo ngaphambili.

Kodwa khumbula, lesi yisifo esikhula kancane kakhulu. Ngakho-ke, kunesikhathi esanele sokucabanga ngezinguquko ezizayo nokwenza izinguquko ngokufanele. Akekho ongasho ngokuqinisekile ukuthi lokhu kuzokuthinta kanjani. Kodwa,Ngendlela enethemba, kunezinto eziningi ongazenza ukuze ulondoloze impilo yakho yonke kanye nenhlalakahle yakho eminyakeni ezayo.

Izinto ezibaluleke kakhulu okudingeka sizikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ngakho-ke sesikhulume kakhulu nge-'Inclusion Body Myositis (IBM)'. Okokugcina, nazi izinto ezibaluleke kakhulu okudingeka uzikhumbule:

• I-IBM yisifo sobuthakathaka bemisipha esiqhubekayo esivame kakhulu ngemva kweminyaka engu-50. Ubuhlungu buncane, kodwa ngokuhamba kwesikhathi bungathinta imisebenzi yansuku zonke.
• Akukho ukwelashwa kwalokhu , kodwa ukwelashwa ngokomzimba kanye nokuzivocavoca kungasiza ekugcineni amandla emisipha isikhathi eside ngangokunokwenzeka.
• Izimpawu zingase zihlanganise ubunzima bokubamba izinto, ukukhubeka ngenkathi uhamba, kanye nobunzima bokugwinya ukudla .
• Imbangela eqondile ayaziwa (`idiopathic`), kodwa kungaba yinkinga ngesimiso somzimba sokuzivikela.
• Lesi sifo siqinisekiswa kuphela ngokuhlolwa kwemisipha.
• Lokhu akusongeli impilo , kodwa kungathinta ikhwalithi yokuphila.
• Kubaluleke kakhulu ukuhlala unethemba, ulandele iseluleko sezokwelapha, futhi uthole ukwesekwa okudingekayo.

Uma wena noma othile omaziyo ebhekene nalezi zimpawu, kungcono ukufuna iseluleko sezokwelapha. Khumbula, awuwedwa, baningi abantu abangakusiza!

Ubuthakathaka bemisipha , isifo se-IBM, ukwelashwa ngokomzimba, izifo zemisipha, impilo yabantu asebekhulile, ubunzima bokugwinya, izifo zezinzwa