Uma wena noma othandekayo wakho kutholakala ukuthi unomdlavuza, kuyinto evamile ukuzizwa unelukuluku kakhulu, futhi mhlawumbe novalo, mayelana nokwelashwa okuzonikezwa. Ikakhulukazi uma unikezwe umuthi othize njenge-Ivosidenib (Tibsovo), kubaluleke kakhulu ukwazi kahle ukuthi uyini. Ngakho-ke namuhla, ake sixoxe ngalo muthi obizwa ngokuthi i-Ivosidenib, kalula kakhulu, ngolimi ongaluqonda.
Uhlobo luni lomuthi i-Ivosidenib?
Kalula nje, lolu uhlobo "lokwelashwa okuqondiwe." Luhlasela amaprotheni athile kumaseli omdlavuza futhi luwavimbele ekukhuleni. Lo muthi usetshenziswa kakhulu ukwelapha izimo ezimbili.
1. I-Acute Myelogenous Leukemia (AML): Lona umdlavuza okhula egazini nasemongweni wamathambo.
2. I-Cholangiocarcinoma: Lona umdlavuza okhula ohlelweni lwe-bile duct emzimbeni wethu.
Udokotela wakho angase futhi akunike lo muthi kwezinye izimo. Uma unemibuzo ngalokhu, buza udokotela wakho.
Yini okufanele ngiyitshele udokotela ngaphambi kokuqala lo muthi?
Ngaphambi kokuba udokotela wakho akunike lo muthi, kufanele umtshele nakanjani uma unanoma yiziphi zalezi zimo. Lolu lwazi lubaluleke kakhulu ekuphepheni kwakho.
- Uma unesifo sezinzwa esibizwa ngokuthi i-Guillain-Barre syndrome .
- Uma unomlando wesifo senhliziyo noma ukushaya kwenhliziyo okungajwayelekile.
- Uma unesifo sezinso noma isifo sesibindi.
- Uma utshelwe ukuthi amazinga akho e-sodium, potassium, noma magnesium egazini aphansi.
- Uma uke waba nokusabela kokungezwani komzimba ne-ivosidenib noma yimuphi omunye umuthi, ukudla, noma idayi.
- Uma ukhulelwe noma uzama ukukhulelwa. (Lokhu kubaluleke kakhulu)
- Uma ungumama oncelisayo.
Ungayisebenzisa kanjani imithi ngendlela efanele?
Ukulandela imiyalelo eqondile yokusebenzisa lo muthi kubalulekile ukuze ukwelashwa kuphumelele.
- Leli iphilisi oliphuza ngomlomo. Lithathe njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanayo nsuku zonke .
- Ungaliphuli, ulichoboze, noma ulihlafune. Gwinya lonke iphilisi ngamanzi.
- Ungakuthatha lokhu ngaphambi noma ngemva kokudla, kodwa uma uzwa ubuhlungu besisu, kungcono ukukuthatha kanye nokudla.
- Khumbula! Ungawuthathi lo muthi kanye nokudla okunamafutha amaningi.
- Enye into ebalulekile! Ungalokothi uthathe lo muthi kanye nejusi yamagilebhisi.
- Qhubeka uthatha umuthi kuze kube yilapho udokotela ekutshela ukuthi uyeke.
Wenzani uma uphuza umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, ungalibali. Shayela ngokushesha iNational Poisons Information Centre eColombo National Hospital , noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Kuthiwani uma ngiphuthelwa umthamo wemithi?
Uma ukhohlwa ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula, kuphela uma sekudlule amahora angaphezu kwangu-12 ngaphambi komthamo wakho olandelayo. Uma sekuseduze nesikhathi somthamo wakho olandelayo (ngaphansi kwamahora angu-12), yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.
Uma uhlanza ngemva kokuthatha iphilisi, ungalithathi elinye iphilisi. Thatha umthamo wakho olandelayo ngesikhathi esibekiwe.
Eminye imithi engase ihlangane nalo muthi (Ukusebenzisana Kwezidakamizwa)
I-Ivosidenib iyisidakamizwa esingasebenzisana neminye imithi, ngakho tshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini kanye nemithi yamakhambi).
| Uhlobo lwesidakamizwa | Amanothi nezibonelo |
|---|---|
| Imithi okungafanele ithathwe | I-Cisapride, i-Dronedarone, i-Pimozide, i-Thioridazine |
| Eminye imithi yokulwa namagciwane ye-HIV noma i-Hepatitis | Lokhu kungashintsha imiphumela ye-Ivosidenib. |
| Imithi yokutheleleka kwesikhunta | Isibonelo: I-Fluconazole, i-Itraconazole, ne-Ketoconazole |
| Imithi yokushaya kwenhliziyo okungajwayelekile | Isibonelo: i-Amiodarone, i-Quinidine, i-Propafenone |
| Imithi yokwelapha isithuthwane/ ukuquleka | Isibonelo: i-Carbamazepine, i-Phenobarbital, i-Phenytoin |
| Ama-hormone abesifazane namaphilisi okulawula ukuzalwa | Ukusebenza kahle kwamaphilisi okuvimbela inzalo kungancipha. |
| I-wort kaSt. John | Nakuba lokhu kungumkhiqizo wezitshalo, kungase kuhlangane nemithi. |
| Eminye imithi enweba isikhathi se-QT sokushaya kwenhliziyo | Lokhu kungabangela ushintsho oluyingozi lwesigqi senhliziyo. |
Izinto okufanele uziqaphele kakhulu lapho uthatha umuthi
- Imiphumela emibi evamile: Kuvamile ukuzizwa unekhanda elincane noma udidekile ngenkathi uthatha lo muthi. Lokhu kungenxa yokuthi ukwelashwa komdlavuza kungathinta kokubili amangqamuzana omdlavuza kanye namaseli anempilo. Uma uhlangabezana nanoma yimiphi imiphumela emibi, tshela udokotela wakho. Qhubeka uthatha umuthi kuze kube yilapho udokotela wakho ekutshela ukuthi uyeke.
- Ukuhlolwa kwegazi: Udokotela wakho uzokuyala ukuhlolwa kwegazi okuvamile ngenkathi uthatha lo muthi. Kubalulekile ukuthi ungakweqi.
- Ukukhulelwa kanye nokuzala: Lena indaba ebaluleke kakhulu.
Kufanele ugweme ukukhulelwa ngenkathi uthatha lo muthi. Uma ungowesifazane, uzama ukukhulelwa, noma usola ukuthi ukhulelwe, tshela udokotela wakho ngokushesha. Uma uyindoda, kufanele ugweme ukuba nguyise wengane ngenkathi uthatha lo muthi. Lokhu kungadala umonakalo omkhulu enganeni engakazalwa.
- Ukulawula ukubeletha: Amaphilisi okulawula ukubeletha angase angasebenzi kahle ngenkathi uthatha lo muthi, ngakho qiniseka ukuthi ukhuluma nodokotela wakho mayelana nokusebenzisa uhlobo olwengeziwe lokulawula ukubeletha (isib. amakhondomu).
- Ukuncelisa: Gwema ukuncelisa ingane yakho ngenkathi uthatha lo muthi futhi inyanga eyodwa ngemuva komthamo wokugcina.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, i-Ivosidenib ingabangela imiphumela emibi. Eminye mincane, kanti eminye idinga ukunakekelwa okusheshayo.
| Ukuhlukaniswa kwemiphumela emibi | |
|---|---|
| Imiphumela emibi okufanele uyibike kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Ukuvuvukala | Ukukhuluphala okungazelelwe; ukuvuvukala kwamaqakala, izinyawo, izandla; ubunzima bokuphefumula. |
| Izinguquko ekushayeni kwenhliziyo | Ubunzima bokuphefumula, ubuhlungu besifuba, isiyezi, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukuquleka. |
| Ezinye izimpawu ezinkulu | Umkhuhlane, ukushintsha kombono, ubunzima bokuchama, izilonda emlonyeni, ubuhlungu noma ukungakhululeki ezithweni, ukukhathala okukhulu. |
| Imiphumela emibi okufanele ibikwe kudokotela uma iqhubeka noma ikhathaza | |
| Izinkinga zesistimu yokugaya ukudla | Ukuqunjelwa, uhudo, isicanucanu, ukuhlanza, ubuhlungu besisu. |
| Ezinye izici ezincane | Ukulahlekelwa yisifiso sokudla, ubuhlungu bamalunga, ubuhlungu bemisipha. |
Ugcina kanjani imithi yakho iphephile?
- Gcina kude nezingane nezilwane ezifuywayo.
- Gcina endaweni yokushisa yegumbi (phakathi kwama-degrees Celsius angu-20-25).
- Lahla imithi ephelelwe yisikhathi. Buza udokotela wakho ngendlela efanele yokuyilahla. Ungase ukwazi ukuthola ulwazi mayelana nezinhlelo zokuthatha imithi.
Umlayezo Wokuya Nawe Ekhaya
- Gwinya iphilisi le-Ivosidenib liphelele, ngaphandle kokuliphula, ukulichoboza, noma ukulihlafuna. Lithathe ngesikhathi esifanayo nsuku zonke.
- Gwema ukuthatha lo muthi kanye nejusi yamagilebhisi kanye nokudla okunamafutha ngokuphelele.
- Tshela udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nemikhiqizo yamakhambi oyithathayo.
- Gwema ukukhulelwa ngenkathi uthatha lo muthi. Sebenzisa enye indlela yokuvimbela inzalo.
- Funa usizo lwezokwelapha ngokushesha uma uhlangabezana nemiphumela emibi efana nobuhlungu besifuba, ubunzima bokuphefumula, noma ukuvuvukala.
- Lo muthi ungowakho wedwa. Ungalokothi wabelane ngawo nabanye.
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