Kuyini i-Spindle Cell Sarcoma? Ake sixoxe ngakho kalula!

Wake wakhathazeka ngento engavamile, njengobuhlungu noma ukuvuvukala emathanjeni akho noma izindawo ezithambile njengemisipha yakho? Ngezinye izikhathi lokhu kungaba okuvamile. Kodwa, akuvamile, lezi zimpawu zingaba uphawu lwento engathi sína. Ngakho-ke, namuhla sizokhuluma ngohlobo lomdlavuza olungavamile kancane, kodwa okubalulekile ukwazi ngalo. Lokho kubizwa ngokuthi i-Spindle Cell Sarcoma.

Iyini ngempela i-Spindle Cell Sarcoma?

Kalula nje, i-Spindle Cell Sarcoma uhlobo lomdlavuza olungavamile oluvela emathanjeni nasezicutshini ezithambile zomzimba wethu. Ubuwazi ukuthi igama elithi 'sarcoma' libhekisela ezinhlayiyeni zamangqamuzana ezingavamile, noma izimila, ezikhula kulawo mathambo nasezicutshini ezixhumene nawo?

Manje, into ekhethekile nge-Spindle Cell Sarcoma ukuthi uma ubheka lawo maseli angajwayelekile ngaphansi kwe-microscope, abukeka 'njenge-spindle'. I-spindle iyisimo esifana nekhandlela, izinhlangothi zincane kanti phakathi nendawo zinobukhulu obuncane. Yingakho yaqanjwa igama layo.

Ngenxa yokuhlolwa kwelebhu okuthuthukisiwe, odokotela bakwazile ukuhlonza izinhlobo ezingaphezu kuka-75 ze-sarcoma. I-Spindle cell sarcoma ingenye yalezi zinhlobo. Eqinisweni, igama elithi 'spindle cell sarcoma' lisetshenziselwa ukuchaza ama-sarcoma angenakuhlukaniswa ngokunembile ngezivivinyo ezithile zelebhu, njengezibazi noma izici zofuzo. Ngakho-ke, igama elibanzi kancane.

Zivame ukuvela kuphi lezi zimila?

I-Spindle Cell Sarcoma ivame ukuvela emathanjeni amade emizimba yethu. Isibonelo:

• Ithambo lakho lethanga (`femur`)
• Ithambo lesifuba (i-tibia)
• Ithambo lengalo engenhla (i-humerus)

Kodwa-ke, akuzona lezi zindawo kuphela. Abanye abantu bane-spindle cell sarcomas ethangeni, ekhanda nasentanyeni, nakwezinye izingxenye zomzimba.

Yiziphi izinhlobo eziyinhloko ze-Spindle Cell Sarcoma?

Manje, bheka, wonke ama-sarcoma aqala ezicutshini ezithambile. Okusho ukuthi, ezintweni ezinjengamafutha, imisipha, imithambo yegazi, imizwa, kanye nezicubu ezizungeze amathambo. Odokotela bahlukanisa ama-sarcoma e-spindle cell ngokusekelwe ohlotsheni lweseli lapho umdlavuza uqala khona.

Ngokuqonda uhlobo lweseli kanye nezici zalo ngale ndlela, odokotela bangahlola ukuthi umdlavuza ungasakazeka kangakanani. Lokhu kubasiza futhi ukuthi bathole izindlela zokwelapha ezingcono kakhulu.

Nakuba igama elithi 'spindle cell sarcoma' liyigama elibanzi, kunezinhlobo eziningana eziyinhloko:

• I-Sarcoma ye-Pleomorphic engahlukaniseki:Njengoba igama lisho, amangqamuzana akulolu hlobo lomdlavuza 'awahlukanisiwe'. Lokhu kusho ukuthi akucaci ukuthi umdlavuza waqala kuluphi uhlobo lweseli. Amangqamuzana anesifo esimilayo 'ayi-pleomorphic', okusho ukuthi eza ngezimo nobukhulu obuhlukahlukene. Ngamanye amazwi, isimila siyiqoqo lamangqamuzana avela ezinhlotsheni ezahlukene.
• I-Fibrosarcoma: Lokhu kuvela kumaseli abizwa ngokuthi ama-fibroblast. Ama-Fibroblast ayizakhi eziyinhloko zezicubu ezixhumene emizimbeni yethu.
• I-Leiomyosarcoma: Lokhu kuqala kumaseli emisipha abushelelezi. Lawa ahlukile kumaseli asezicutshini zemisipha yamathambo, esiwasebenzisa ukuhambisa imizimba yethu nokuthola amandla. Amaseli emisipha abushelelezi atholakala ezithweni zethu zangaphakathi, emigodini yomzimba, nakwamanye amathambo njengezicubu ezithambile.

Sivame kangakanani lesi simo?

Njengezinye izinhlobo ze-sarcoma, i-spindle cell sarcoma ayivamile kakhulu . Eqinisweni, ibangela ngaphansi kuka-10% wabo bonke umdlavuza wamathambo nezicubu ezithambile. Khumbula, akuvamile kangangokuthi udokotela wakho angase angasoli lolu hlobo lomdlavuza ekuqaleni. Kungase kudingeke uye kodokotela abaningana, ubone ochwepheshe abaningana, futhi wenze izivivinyo eziningana ngaphambi kokuba uthole ukuxilongwa.

I-spindle cell sarcoma ingakhula kunoma ubani. Kodwa-ke, ivame kakhulu kubantu abangaphezu kweminyaka engama-40. Abantu abahlakulela i-pleomorphic sarcoma engahlukanisiwe ngaphambilini bavame ukuba phakathi kweminyaka engama-60 nengama-70.

Ziyini izimpawu zalokhu?

Izimpawu ze-spindle cell sarcoma zingahluka. Ziya ngobukhulu besimila, inani lezimila, kanye namathambo (noma ezinye izingxenye zomzimba) amangqamuzana omdlavuza akuwo. Nazi ezinye izimpawu okufanele uziqaphele ngokukhethekile :

• Ubuhlungu bamathambo: Lobuhlungu bungaba njalo noma bufike budlule. Bungazwakala sengathi othile ukugwaza ngaphakathi.
• Ukuphuka kwethambo endaweni ebuthaka ngenxa yomdlavuza: Lokhu kubizwa ngokuthi 'ukuphuka kwethambo okubangelwa yisifo.' Ithambo lingaphuka ngisho noma liwile kancane.
• Ubuhlungu noma ukuvuvukala uma ucindezelwa endaweni lapho kukhona khona isimila: Kungase kube nesimila esikhulu ngokwanele ukuba singabanjwa esandleni.
• Ukungakwazi ukuhambisa ilunga eduze kwesimila kahle: Cabanga uma idolo liseduze, kungaba nzima ukugoba noma ukwelula idolo.
• Ukukhathala: Lokhu akusikho nje ukukhathala okuvamile. Kuwukukhathala okukhulu okungapheli kungakhathaliseki ukuthi ulala noma uphumule kangakanani.
• Ubuhlungu: Ukuzizwa ungaphilile , ngaphandle kwesizathu esibonakalayo, njengokungathi awunawo amandla noma intshisekelo kunoma yini.

Yini ebangela i-spindle cell sarcoma?

Njengazo zonke ezinye izinhlobo zomdlavuza, i-spindle cell sarcoma iqala lapho amangqamuzana aphilile eba yingozi. Lawa maseli anobungozi akhula engalawuleki, akhe izimila. Lawa mathumba angalimaza izicubu ezinempilo ezizungezile. Into eyingozi kakhulu ukuthi lawa maseli omdlavuza angahlukana nesimila sokuqala futhi asakazeke emzimbeni wonke, alimaze ezinye izicubu nezitho zomzimba. Lokhu yilokho esikubiza ngokuthi i-metastasis, noma umdlavuza we-metastatic.

Kodwa, nansi into okufanele uyazi. Ngokuvamile, amaseli e-spindle (uma ekhula kahle) empeleni ayinto enhle. Amaseli e-spindle akheka lapho izicubu zonakaliswe khona. Ngakho-ke, ukuba namaseli e-spindle kuyisibonakaliso sokuthi inxeba lakho liyaphola. Lawa maseli ayanyamalala lapho inxeba liphola.

Kodwa-ke, ku-spindle cell sarcoma, lawa maseli e-spindle ayaqhubeka nokukhula nokwanda. Ososayensi abakatholi isizathu esisodwa esiqondile sokuthi kungani lawa maseli eba yingozi kangaka.

Kodwa-ke, abacwaningi bathole ukuthi izinguquko ezithile zofuzo zingandisa ingozi yomuntu yokuthola lo mdlavuza. 'Ukuguqulwa' kuyiphutha ezakhiweni zethu zofuzo, uhlelo olutshela amangqamuzana ethu ukuthi asebenze kanjani. Endabeni ye-spindle cell sarcoma, lezi zinguquko zivame ufuzo, okusho ukuthi zingasebenza emindenini.

Yiziphi izinto ezibangela ingozi yokuthuthukisa lo mdlavuza?

Kunezici eziningana ezingandisa ingozi yokuthola i-spindle cell sarcoma. Ake sibheke ukuthi ziyini:

• Ukuvuvukala Kwamathambo: Lokhu kwenzeka lapho izicubu zamathambo zifa ngoba azitholi igazi elanele. Njengoba wazi, izicubu zamathambo zidinga igazi ukuze ziphile, yilokho okwenziwa umoya-mpilo.
• I-Fibrous Dysplasia: Kulesi simo, izicubu zamathambo ezinempilo zithathelwa indawo yizicubu ezifana nethambo ezine-fibrous. Lokhu kwandisa ingozi yokuqhekeka futhi (kancane kakhulu) kungaholela ekukhuleni kwe-fibrosarcomas.
• I-Osteomyelitis: Lokhu ukutheleleka okuthinta izicubu ezithambile ngaphakathi kwamathambo athile, okubizwa ngokuthi umongo wamathambo. Lokhu kungenzeka uma amabhaktheriya noma amanye amagciwane ehamba esuka egazini lakho eya ethanjeni futhi athelele amaseli lapho.
• Isifo sethambo sikaPaget: Lesi yisimo sesikhathi eside (esingamahlalakhona). Sibangela ukuba amathambo abe buthakathaka futhi aphuke kalula. Lokhu kungandisa ingozi yokuba nomdlavuza wamathambo, okuhlanganisa ne-spindle cell sarcoma.
• Njengoba ngithole ukwelashwa ngemisebe yomdlavuza ngaphambilini:Ukwelashwa ngemisebe kusebenzisa imisebe enamandla aphezulu (ngokuvamile ama-X-ray anamandla aphezulu) ukubhubhisa amangqamuzana omdlavuza. Akuvamile ukuthi ama-sarcoma e-spindle cell akheke ezindaweni eziphathwe ngemisebe. Uma lokhu kwenzeka, i-sarcoma ivame ukukhula eminyakeni eminingana ngemva kokwelashwa (iminyaka eyisikhombisa kuya kwengamashumi amabili). Kodwa khumbula, abantu abangaphansi kuka-1% abathola ukwelashwa ngemisebe bathola lolu hlobo lomdlavuza ohlobene nemisebe.

Yiziphi izinkinga ze-spindle cell sarcoma?

Lo mdlavuza wenza amathambo akho abe sengozini enkulu yokuphuka (ukuphuka) endaweni yesimila. Uma ithambo liphuka, amangqamuzana omdlavuza avela kulesi simila angahamba aye ezindaweni eziseduze.

Kodwa-ke, kusenempikiswano mayelana nokuthi lolu hlobo lokuphuka kwamathambo luyawenza yini umehluko esibikezelweni esiphelele (okungukuthi, umphumela ongaba khona) womdlavuza, noma ukuthi umphumela uhlobene kuphela nokusabalala okude komdlavuza (ukusabalala kwe-metastatic).

I-sarcoma ye-spindle cell itholakala kanjani?

Ngaphambi kokuba udokotela wakho akwazi ukuxilonga nokuhlola umdlavuza wakho, cishe uzoba nezivivinyo nezinqubo eziningana. Ukuhlola umdlavuza kuvumela odokotela ukuthi bahlukanise ubukhulu bomdlavuza ngokusekelwe kubukhulu besimila, indawo yaso, nokuthi ngabe sisabalale yini. Lapho behlola umdlavuza wamathambo, babheka nokuthi ngabe isimila 'sisezingeni eliphezulu' noma 'sisezingeni eliphansi'. Izimila zezinga eliphezulu zinamaseli abukeka engajwayelekile . Amathuba amaningi okukhula nokusabalala ngokushesha.

Ama-sarcoma amaningi e-spindle cell asezingeni eliphezulu.

Ukuhlolwa kwezithombe

Nakuba ukuhlolwa kwezithombe kungakwazi ukutshela uhlobo lomdlavuza, kungabonisa ubukhulu nendawo yesimila. Kungabonisa nokuthi umdlavuza ususakazeke ngale kwesimila esiyinhloko.

• Ama-X-ray: Ama-X-ray angabonisa izimila noma ezinye izinkinga emathanjeni akho. I-X-ray yesifuba ingabona ukuthi umdlavuza ususakazekele emaphashini. I-Metastatic spindle cell sarcoma ivame ukusakazekela emaphashini kuqala.
• I-MRI Scan: I-MRI isebenzisa i-magnet enkulu, amaza omsakazo, kanye nekhompyutha ukuthatha izithombe zezinto ezingaphakathi emzimbeni. Ngokungafani ne-X-ray, i-MRI ingabonisa izicubu ezithambile ngemininingwane eminingi. Lokhu kuwusizo kakhulu kodokotela ukuthola amaqhubu ezicubu ezithambile abasola ukuthi angaba yi-sarcomas.
• Ama-CT Scan: Ama-CT scan asebenzisa ama-X-ray kanye nekhompyutha ukwenza izithombe zamathambo nezicubu ezithambile ezinezinhlangothi ezintathu (3D). Endabeni ye-spindle cell sarcoma, ama-CT scan angabonisa ukuthi umdlavuza ususakazekele yini ezicutshini ezithambile. Angcono kakhulu futhi ekutholeni ama-fracture noma izindawo lapho amathambo ebuthaka khona.
• Ukuskena Kwe-PET: Ukuskena kwe-PET kusebenzisa into ebizwa ngokuthi i-tracer ukuthola amangqamuzana omdlavuza kuwo wonke umzimba. Kungasiza ekutholeni i-metastasized spindle cell sarcoma. Ungase futhi wenze i-PET scan ukuze ubone ukuthi ukwelashwa kwakho kusebenza kanjani. Kodwa-ke, ukuskena kwe-PET akusetshenziselwa zonke izinhlobo ze-sarcoma. Udokotela wakho uzonquma ukuthi ukuskena kwe-PET kukufanele yini.

Ukuhlolwa kwegazi

Akukho ukuhlolwa kwegazi okuqondile okungabona i-spindle cell sarcoma. Kodwa-ke, ukuhlolwa kwegazi kunikeza ulwazi olubalulekile mayelana nempilo yakho, futhi kubalulekile ukuthi udokotela wakho azi lolo lwazi. Ngokuvamile, ukuhlolwa kwegazi kungakunikeza ulwazi ngezinto ezifana nalezi:

• Amaseli akho egazi
• Umsebenzi wesitho
• Amazinga e-enzyme (ama-enzyme angamakhemikhali asiza izitho zomzimba ukuthi zenze izinqubo ezibalulekile)

Ukuhlolwa kwebhayoloji

Indlela engcono kakhulu yokwazi ngokuqinisekile ukuthi iqhubu linomdlavuza yini ukwenza i-biopsy. Futhi kuyindlela kuphela yokwazi uhlobo lomdlavuza kanye nezinga lawo. Ngesikhathi se-biopsy, udokotela uthatha isampula yezicubu ezivela eqhubuni alithumele elebhu ukuze lihlole amangqamuzana.

Iningi labantu abane-spindle cell sarcoma bahlolwa ngenaliti. Odokotela bavala izicubu ezizungeze isimila bese besebenzisa inaliti encane, engenalutho ukuthatha isampula. Ukuze usize udokotela azi kahle ukuthi kufanele afake inaliti kuphi emzimbeni wakho, ungadinga ne-X-ray noma i-CT scan.

Iphathwa kanjani i-spindle cell sarcoma?

Ukwelashwa okutholayo kuzoncika empilweni yakho, indawo, usayizi, ibanga, nezinye izici. Kuncike futhi ekutheni uthola ukwelashwa okokuqala noma ukuthi umdlavuza ubuyile yini ngemuva kokwelashwa (okuphindayo).

Ukuhlinzwa

Umgomo wokuhlinzwa ukususa isimila ngenkathi kulondolozwa ithambo lakho eliningi ngangokunokwenzeka. Uma yonke iminonjana yomdlavuza esimila esiyinhloko kanye nezimila zesibili ingasuswa, umdlavuza ungelapheka. Kodwa-ke, uma umdlavuza ususakazeke ngale kwesimila sokuqala, kunzima kakhulu ukuwususa ngokuphelele.

Ukwelashwa ngamakhemikhali

Ukwelashwa ngamakhemikhali kuyindlela yokwelapha esebenzisa imithi ukubulala amangqamuzana omdlavuza emzimbeni wonke. Unganikwa i-chemotherapy ngaphambi kokuhlinzwa ukuze unciphise isimila futhi kube lula ukusisusa. Noma, unganikwa i-chemotherapy ukuze ubulale noma yimaphi amangqamuzana omdlavuza asele ngemva kokuhlinzwa. Ukwelashwa ngamakhemikhali nakho kusetshenziswa 'njengokunakekelwa kobuhlungu'. Nakuba kungenakuphulukisa umdlavuza, i-chemotherapy ingabulala amangqamuzana omdlavuza ukuze kuncishiswe izimpawu ezifana nobuhlungu emathanjeni.

Abantu abaningi banikezwa inhlanganisela yemithi ye-chemotherapy ukuze ukwelashwa kuphumelele kakhudlwana. Kuye ngokuthi uthola ukwelashwa okokuqala, awusabeli kahle kweminye yemithi ye-chemotherapy, noma uma umdlavuza ubuyile ngemva kokungena "ekukhululweni," ungase unikezwe imithi ye-chemotherapy ehlukene. "Ukukhululwa" kusho ukuthi umdlavuza usungcono noma usuphelile ngokuphelele ngemva kokwelashwa.

Ukwelashwa Ngemisebe

Ukwelashwa Ngemisebe Yangaphandle (i-EBRT) kusebenzisa umshini ukuqondisa ama-X-ray esimila ukuze kubulawe amangqamuzana omdlavuza. Uma ungakwazi ukuhlinzwa, ukwelashwa ngemisebe kungase kunikezwe ukuze kubhujiswe isimila. Ngezinye izikhathi, udokotela ohlinzayo angase angakwazi ukufinyelela isimila ngokuhlinzwa. Kungase kube kujule kakhulu ezicutshini noma kusondele kakhulu ezithweni ezibalulekile ukuba kususwe ngokuphephile. Ezimweni ezinjalo, ungase unikezwe ukwelashwa ngemisebe esikhundleni salokho.

Njengokwelashwa ngamakhemikhali, ukwelashwa ngemisebe nakho kunganciphisa izimpawu uma umdlavuza ungelapheki.

Yiziphi izinkinga noma imiphumela emibi yokwelashwa?

Kuvamile ukuba nemiphumela emibi evela ku-chemotherapy kanye nokwelashwa ngemisebe ngesikhathi sokwelashwa komdlavuza. Lokhu kungase kuqhubeke isikhathi esithile ngemva kokuphela kokwelashwa. Kubalulekile ukubuza udokotela wakho ngemiphumela emibi engaba khona, kuye ngokuthi uthola ukwelashwa ini.

Kufanele ngimbone nini udokotela wami?

Udokotela wakho uzokutshela ukuthi udinga ukuza kangaki ukuzokwelashwa, noma ukuhlolwa ukuze kubonakale ukuthi umdlavuza "usaphilile." Abantu abaningi abanomdlavuza abaphilile kuzodingeka baye kudokotela kaningi ezigabeni zokuqala. Njengoba uhlala ungenawo umdlavuza isikhathi eside, inani lama-aphoyintimenti okulandelela ukuze kuhlolwe ukuthi awuphinde ubuye yini lizoncipha.

Hlobo luni lokwelashwa okulandelayo engiludingayo?

Kuye ngokuthi ithambo elingakanani okwakudingeka lisuswe udokotela ohlinzayo, ungase udinge izinqubo ezengeziwe. Lezi zinqubo zisiza ekugcineni ukusebenza kwethambo. Isibonelo, ungase udinge ukufakelwa kwethambo. Ukufakelwa kwethambo kuhilela ukufaka esikhundleni izicubu ezisusiwe ngezicubu ezivela kwenye ingxenye yomzimba wakho noma ezivela kumnikeli. Ungase udinge nesitho sokwenziwa. Ungase udinge ukwelashwa okwengeziwe ukuze kukusize uvumelane nalezi zinguquko.

Yimiphi imibuzo okufanele ngiyibuze udokotela wami mayelana ne-spindle cell sarcoma?

Nazi ezinye zemibuzo ebalulekile okufanele uyibuze udokotela wakho:

• Uphi umdlavuza?
• Iyini isigaba/izinga lomdlavuza?
• Leso sigaba/ibanga lithinta kanjani uhlelo lwami lokwelashwa?
• Yimiphi imiphumela emibi yokwelashwa okufanele ngiyilindele?
• Ingabe umdlavuza wami ungelapheka?
• Iyini imigomo yokwelashwa?
• Ungangixhumanisa nezinsizakalo zokunakekelwa kobuhlungu ukuze zingisize ngibhekane nokuxilongwa kwami ​​komdlavuza?

Ingabe i-spindle cell sarcoma ingelapheka? Ingakanani ingozi?

Uma zonke izimpawu zomdlavuza zingasuswa, odokotela bangelapha i-spindle cell sarcoma. I-spindle cell sarcoma engakasabalali ngaphezu kwendawo yayo yokuqala kulula kakhulu ukuyilapha. Kodwa-ke, ukwelapha ama-sarcoma asesakazekile kuyinselele kakhulu . Ama-Metastatic Spindle Cell Sarcomas awavamile ukwelapheka.

Lolu hlobo lomdlavuza luvame ukuba 'lusezingeni eliphezulu'. Lokhu kusho ukuthi lukhula ngokushesha futhi lusakazeka ngokushesha. Ngemva kokuphumula, kungenzeka kakhulu ukuthi lubuye, ngezinye izikhathi endaweni efanayo lapho kwakukhona khona isimila sokuqala, ngezinye izikhathi endaweni ehlukile.

Kodwa khumbula, ukuxilongwa ngakunye komdlavuza kuhlukile. Udokotela wakho angakutshela umphumela ongaba khona wokwelashwa (ukubikezela) ngokusekelwe kuhlobo oluthile lomdlavuza onalo, isigaba salo, impilo yakho iyonke, impendulo yakho ekwelashweni, kanye nezinye izici ezahlukahlukene. Udokotela wakho ungumuntu ongcono kakhulu wokukweluleka ngokuthi lokhu kuxilongwa kuzokuthinta kanjani.

Izinto okufanele sizikhumbule kule ndaba (Umyalezo Ohamba Nawo Ekhaya)

Ukuxilongwa nge-Spindle Cell Sarcoma kungaba yinto ekucindezelayo. Lesi simo singakwenza uzizwe ukhathele futhi ungakhululekile. Ukwelashwa kuvame ukuba nzima, futhi ungase ubhekane nezinselele ezifana nokujwayela ukufakelwa kwamathambo noma isitho sokwenziwa.

Ngakho-ke, kubaluleke kakhulu ukuba nengxoxo eqotho nevulekile nodokotela wakho kusukela ekuqaleni. Ngale ndlela, ungaqonda ukuthi unesifo esingakanani, izinga umdlavuza wakho ongalapheka ngalo, ukuthi yiziphi izinhloso zokwelashwa kwakho, nokuthi yiziphi izinguquko zendlela yokuphila okuzodingeka uzenze ngesikhathi sokwelashwa nokululama.

I-Spindle cell sarcoma ingumdlavuza oyingozi, okhula ngokushesha. Kodwa-ke, kunezindlela zokwelapha ezingalawula ukukhula kwawo, futhi kwezinye izimo, ziwuphulukise ngokuphelele. Khuluma nodokotela wakho ngalokho ongakulindela. Ungalokothi ulahle ithemba. Ukulandela iseluleko sezokwelapha esifanele nokuhlala unethemba kubaluleke kakhulu kule mpi.

I-Spindle Cell Sarcoma, I-Spindle Cell Sarcoma, Umdlavuza, Umdlavuza Wamathambo, Umdlavuza Wezicubu Ezithambile, Isimila, Izimpawu, Ukwelashwa