Ake sifunde ngoshintsho emaseli omzimba wethu. Kuyini i-Squamous Metaplasia?

Wake wacabanga ukuthi ngisho namaseli amancane kakhulu emizimbeni yethu angashintsha ngezinye izikhathi? Lokhu kungaba yinto evamile, futhi ngezinye izikhathi kungaba yinto okufanele sikhathazeke ngayo. Olunye ushintsho olunjalo lwamaseli lubizwa ngokuthi `(Squamous Metaplasia)`. Namuhla, sizokhuluma ngalokhu kalula, ngendlela ongayiqonda.

Kuyini ngempela `(Squamous Metaplasia)`?

Kalula nje, i-Squamous Metaplasia iwushintsho olungenabungozi, olungenalo umdlavuza emangqamuzaneni e -epithelium yomzimba wakho. Cabanga ngakho ukuthi le epithelium ifana nesikhumba sethu, ulwelwesi oluvikelayo olumboza izindlala nezitho zethu zomzimba.

Manje sekulula ukubheka izincazelo zala magama amabili ngokwehlukana:

• I-Squamous: Lawa amaseli amancane, ayisicaba afana nezikali. Lawa yiwo akha i-epithelium.
• `(Metaplasia)`: Lokhu kusho ukuthi uhlobo olulodwa lweseli luyashintsha futhi lube uhlobo oluhluke ngokuphelele lweseli. Into ekhethekile ukuthi lolu hlobo olusha lweseli olwakhayo yilolo olungatholakali njalo kulolo hlobo lwezicubu.

Ngakho-ke, ku-`(Squamous Metaplasia)`, amaseli ajwayelekile `(squamous)` athathelwa indawo amaseli `(squamous)`. Kodwa isikhathi esiningi lokhu akuwona umdlavuza. Kodwa kwezinye izimo ezingavamile, lesi simo singaba umdlavuza `(oyingozi).`

Ingabe kukhona izinhlobo ze-`(Squamous Metaplasia)`?

Yebo, odokotela bahlukanisa la maseli ngokuthi "i-Squamous Metaplasia" ngokusekelwe endleleni ashintsha ngayo. Kunezinhlobo ezimbili eziyinhloko:

1. `I-Keratinizing Squamous Metaplasia` noma `(Leukoplakia)`:

• Kulolu hlobo, amangqamuzana akho akhiqiza iphrotheni ebizwa ngokuthi i-keratin njengoba ehamba esuka kolunye ungqimba lwe-epithelium aye kolunye.
• Kumaseli ajwayelekile anempilo aqinile, le phrotheni ebizwa ngokuthi i-keratin isiza ekwakheni izicubu zethu, izinwele, isikhumba, kanye nezinzipho. Yakha futhi ulwelwesi lwezitho kanye nezindlala.
• Kodwa kulolu hlobo, i-`(keratin)` eningi kakhulu iyaqongelela.

2. `I-Non-keratinizing Squamous Metaplasia`:

• Okwenzekayo kulokhu ukuthi, njengoba kushiwo ngaphambili, inani elikhulu lamaprotheni (okungukuthi, `(keratin)`) aliqongelelani ngaphakathi kwamaseli. I-Keratinization ayenzeki.

Kulezi zinhlobo ezimbili, eyodwa ifanelwe ukunakwa.

Ngakho-ke ingabe lokhu kuyimbangela yomdlavuza? Ingabe isimo "esingaphambi komdlavuza"?

Lena yinto ebaluleke kakhulu.

• I-Nonkeratizing Squamous Metaplasia ayiyona inkinga yomdlavuza. Lokhu kusho ukuthi ngeke iphenduke umdlavuza. Ngakho-ke akukho okufanele ukhathazeke ngakho.
• Kodwa-ke, i-'Keratinizing Squamous Metaplasia'Lolu hlobo ngezinye izikhathi lungaba "olungaphambi komdlavuza". Lokhu kusho ukuthi uma lungelashwa kahle, lungase lukhule lube umdlavuza ngokuhamba kwesikhathi.

Yingakho odokotela benaka kakhulu uma bethola `(i-Keratinizing Squamous Metaplasia)'.

Kwenzekani uma i-Squamous Metaplasia iba nomdlavuza?

Umbuzo omuhle. Uma isimo okukhulunywe ngaso ngaphambilini, i-"Keratinizing Squamous Metaplasia", singelashwa, sizoqala sibe yisimo esibizwa ngokuthi i-"Dysplasia ." I-"Dysplasia" iwukwanda okungavamile kwenani lamaseli ezicutshini noma ezithweni zomzimba. Cabanga ngakho njengeqembu lamaseli asebenza ngaphandle komthetho.

Uma lesi simo se-`(Dysplasia)` singelashwa, singaba yi -`(Neoplasia)` (neoplasia) . Ngemuva kwalokho, okwenzekayo ukuthi lawo maseli angajwayelekile akhula ngokushesha ngaphandle kokulawulwa, akha i-`(neoplasm)` (neoplasm), okungukuthi, i-`(tumor).` Lesi simila singaba umdlavuza noma singabi umdlavuza.

Uma amangqamuzana e-squamous eba umdlavuza, siwubiza ngokuthi i-squamous cell carcinoma . Kungenzeka ukuthi uke wezwa leli gama njengohlobo lomdlavuza wesikhumba. Kodwa umdlavuza wesikhumba uhlobo olulodwa kuphela. Lawa maseli e-squamous atholakala nasezingxeni zomlomo wethu, ekhaleni, emigudwini yomoya, kanye nasesibelethweni.

Kuyini i-Cervical Squamous Metaplasia?

Nakuba lesi simo, esibizwa ngokuthi i-Squamous Metaplasia, singavela noma kuphi ku-epithelium yethu, sivame ukubonakala emangqamuzaneni akha ama-mucus e-endocervix, ingxenye yesistimu yokuzala yabesifazane. I-endocervix iyindlela yokungena ngaphakathi komlomo wesibeletho exhumanisa isibeletho nesitho sangasese sowesifazane.

Okubalulekile, i-Nonkeratinizing Cervical Squamous Metaplasia ivame kakhulu kwabesifazane. Kubhekwa njengoshintsho olujwayelekile. Cishe abesifazane abayisishiyagalombili kwabayishumi abaseminyakeni yokuzala banalesi simo. Sibonakala nakwabesifazane abathathu kwabane abaye badlula esikhathini sokunqamuka kokuya esikhathini. Lokhu kushintsha okuvamile kwamaseli akukhulisi ingozi yomdlavuza.

Kodwa-ke, abanye abantu abangenwe yi -Human Papillomavirus (HPV) bangaba nesimo esibizwa ngokuthi i-Squamous Metaplasia, esingaba yisandulela somdlavuza. Njengoba wazi, i-HPV iyisifo esivame kakhulu esidluliselwa ngocansi (STD). I-Squamous Metaplasia, ebangelwa yi-HPV, ingakhula ibe yisimo esibizwa ngokuthi i-Cervical Dysplasia noma i-Cervical Intraepithelial Neoplasia. Uma ingelashwa, lezi zinguquko zamaseli zingaholela kumdlavuza wesibeletho.

Yingakho odokotela behlala betshela abesifazane ukuthi benze izivivinyo ezifana ne-"Pap Smear". Uma lezi zinguquko zitholakala kusenesikhathi, kulula ukuzelapha.

Kuphi lapho i-Squamous Metaplasia ingenzeka khona?

I-Squamous Metaplasia ingakhula nakwezinye izindawo:

• Isistimu yesinye kanye nomchamo
• Uhlelo lokugaya ukudla
• Amathonsi emlonyeni, olimini, nasemphinjeni
• Uhlelo lokuphefumula
• Isikhumba

Yiziphi izimbangela ze-Squamous Metaplasia?

Ochwepheshe abakakazi kahle ukuthi kungani amanye amangqamuzana eshintsha ngale ndlela, okubangela `(Squamous Metaplasia)`. Kodwa-ke, kunezici eziningana eziye zatholakala ezikhulisa ingozi yokuthuthukisa izinhlobo ezithile ze `(Squamous Metaplasia).` Isibonelo:

• Ukwelashwa ngama-hormone kanye nokwelashwa ngemisebe yomdlavuza we-prostate kwabesilisa kungabangela i-squamous metaplasia ku-urethra (ithubhu elithwala umchamo usuka kwesinyeni uye ngaphandle komzimba).
• Ukutheleleka kwe-HPV kungabangela i-metaplasia ye-cervical squamous.
• Abantu asebenesikhathi eside besebenzisa i-catheterization yomchamo, abanezifo ezivamile zomgudu womchamo (UTIs), noma abanamatshe ezinso bangaba ne-bladder squamous metaplasia.
• Abantu ababhemayo kanye nalabo abanesifo samaphaphu esibizwa ngokuthi i-Chronic Obstructive Pulmonary Disease (COPD) basengozini enkulu yokuthola i-bronchial squamous metaplasia.
• Ukuntuleka kweVithamini A kungabangela i-Squamous Metaplasia endleleni yokuphefumula.

Kungase kube nezizathu eziningana zalokhu, kodwa akunakushiwo ukuthi zonke zibangelwa yilezi zizathu.

Ziyini izimpawu ze-`(Squamous Metaplasia)`?

Izimpawu zalesi simo ziyahlukahluka kuye ngengxenye yomzimba ethintekile yilesi simo (i-Squamous Metaplasia). Abantu abaningi bangase bangabi nazimpawu ezibonakalayo. Lokhu kusho ukuthi lesi simo singaba khona emzimbeni ngaphandle kokubangela ukungakhululeki.

Kodwa abanye abantu bangase babe nezimpawu.

• Abantu abane-metaplasia ye-bladder squamous bangase babe nesidingo sokungalawuleki (isidingo sokuchama ngokuzumayo).
• I-Cervical Squamous Metaplasia ingabangela ukuvuvukala komlomo wesibeletho, okwaziwa ngokuthi i-cervicitis. Lesi simo asihlali sibangela izimpawu. Kodwa-ke, uma kuvela izimpawu, zingase zihlanganise:
• Uketshezi oluphuma esithweni sangasese sowesifazane olunuka kabi noma ukulunywa noma ukusha esithweni sangasese sowesifazane.
• Ubuhlungu ngesikhathi socansi (i-dyspareunia).

Ngakho-ke uyabona, izimpawu zingahluka kumuntu nomuntu, futhi ngezinye izikhathi kungase kungabi nazimpawu nhlobo.

Ungasithola kanjani lesi simo?

Indlela yokuhlola i-Squamous Metaplasia nayo iyahlukahluka kuye ngengxenye yomzimba ethintekile.

• Odokotela basebenzisa ama-Pap smears ukuze babheke izinguquko emaseli esibelethweni kanye ne-endocervix. Baphinde bahlole i-HPV ukuze babone ukuthi uke waba nokutheleleka nge-HPV ngaphambilini. Uma imiphumela yalezi zivivinyo ikhombisa ingozi yokuba nomdlavuza wesibeletho, ungathunyelwa ku -colposcopy . Lokhu kuhilela ukuhlola okwengeziwe amaseli esibelethweni.

• Kwezinye izinhlobo ze-squamous metaplasia, udokotela wakho angathatha isampula yamaseli endaweni ethintekile bese enza i-biopsy . Uchwepheshe (obizwa ngokuthi i-pathologist) uzobe esebheka lawa maseli ngaphansi kwe-microscope ukuze ahlole noma yiziphi izinguquko noma izimpawu zesifo.

Ngakho-ke uma unenkinga yokungakhululeki, noma udokotela esola isimo esinjengalesi, uzokwenza izivivinyo ezifanele.

Iphathwa kanjani i-Squamous Metaplasia?

Uyakhumbula sikhulume ngohlobo olubizwa ngokuthi ``Nonkeratinizing Squamous Metaplasia''? Lolu hlobo aludingi ukwelashwa ngoba aluguquki lube umdlavuza.

Kodwa-ke, uhlobo olubizwa ngokuthi `(Keratinizing Squamous Metaplasia)` lungandisa ingozi yomdlavuza, ngakho-ke kudingeka uqaphele ngakho.

Udokotela wakho uzokwenza izivivinyo njalo ukuhlola noma yiziphi izimpawu zomdlavuza. Uma noma yiluphi ushintsho lweseli lubonisa inkinga, udokotela wakho uzonquma ukuthi iyiphi indlela yokwelapha engcono kakhulu ngokusekelwe engxenyeni yomzimba ethintekile.

Indlela yokwelapha incike ekutheni isimo sibi kangakanani, ukuthi sikuphi, kanye nempilo yakho iyonke.

Yini okufanele ngiyibuze udokotela wami?

Uma kutholakale ukuthi une-Squamous Metaplasia, ungase ube nemibuzo eminingi. Lokhu kuvamile. Nazi ezinye izinto ongazibuza udokotela wakho:

• Yini engaba yimbangela yokuthi ngithuthukise le `(Squamous Metaplasia)`?
• Ingabe ngisengozini yokuthola umdlavuza?
• Yini engingayenza ukuze nginciphise le ngozi?
• Ingabe ngidinga ukwelashwa? Uma kunjalo, hlobo luni?
• Kufanele ngihlolwe kangaki?
• Ingabe kukhona izinkinga okufanele ngikhathazeke ngazo?

Ungesabi ukubuza le mibuzo. Kubaluleke kakhulu ukuthi uqonde kahle isimo sakho.

Umlayezo Wokuya Nawe Ekhaya

I-Squamous Metaplasia ushintsho olungeyona umdlavuza emaseli e-epithelium, izicubu ezimboza izitho zethu kanye nezindlala. Abantu abaningi, ikakhulukazi abesifazane, banohlobo olubizwa ngokuthi i-Nonkeratinizing Cervical Squamous Metaplasia. Lokhu akukhulisi ingozi yomdlavuza.

Kodwa-ke, uhlobo olubizwa ngokuthi ``Keratinizing Squamous Metaplasia'' lungaphenduka ``Dysplasia'' futhi mhlawumbe ngisho nomdlavuza. Ngakho udokotela wakho uzohlola njalo amangqamuzana akho ukuze abone izinguquko ukuze abheke izimpawu zomdlavuza.

Into ebaluleke kakhulu ukuthi uma unokungabaza noma ukungakhululeki, noma uma udokotela ekhuluma ngalokhu, ungesabi ukubuza, uthole ulwazi olufanele, bese uthola ukuhlolwa nokwelashwa okudingekayo (uma kudingeka). Landela njalo iseluleko sikadokotela wakho.

I- Squamous Metaplasia, ushintsho lwamaseli, i-epithelium, i-keratin, i-precancerous, umlomo wesibeletho, i-HPV