Yala i bɛ to ka i farikolo nɛ ta wa? Yala a bɛ kɛ bilen ye wa? An ka nin bana in dɔn min man ca (Mastocytose systémique) .

Yala aw fana bɛ nɛ bɔ aw fari fan bɛɛ la tuma ni tuma wa? Yala aw ɲɛda ni aw kɔ bɛ bilen yɔrɔnin kelen ani a bɛ kɛ i n’a fɔ aw bɛ funteni sɔrɔ wa? Yala kɔnɔdimi bɛ i la, ɲɛnamini bɛ i la, ani dusukun bɛ girin wa? Hali n’aw b’a miiri ko nin fɛn ninnu ye faritanabana dɔrɔn de ye, tuma dɔw la, bana wɛrɛ bɛ se ka kɛ nin kɔfɛ, an ma caman mɛn min ko la. Bi an bɛ kuma o bana sugu dɔ kan min man ca, n’o ye Systemic Mastocytosis ye. Aw kana aw hakili ɲagami, an ka nin faamuya cogo nɔgɔman na.

Mastocytose systémique ye mun ye?

N’an y’a fɔ cogo nɔgɔman na, nin ye bana ye min bɛ sɔrɔ farikolokisɛ suguya dɔ caya cogo la min tɛ bɛn a ma, n’o bɛ wele ko ‘mast cells’ an fari la. Mast cellules ye joli kuru finman suguya dɔ ye. Aw ye miiri o masɔrɔlifɛnw na i n’a fɔ sɔrɔdasi minnu bɛ an ka farikolo tangacogo la. u ka baara kunba ye k' an tanga banaw ma ani k' an dɛmɛ ka kɛnɛya ni an jogin na . Nka nin bana in na, o masɔrɔsiraw bɛ dalajɛ ka tɛmɛ ani cogo la min tɛ bɛn farikolo yɔrɔ suguya caman ma i n’a fɔ an fari, kolotugudaw , kolotugudaw, ani banakɔtaa. Mun bɛ kɛ o tuma na? K’a sababu kɛ fɛn dɔw ye minnu bɛ mɔgɔ bila ka wale kɛ, o masɔrɔsira tɛmɛnenw bɛ barika sɔrɔ ka baara kɛ ani ka furakisɛ caman bɔ farikolo la i n’a fɔ ‘histamine’ . O waati de la ne ye taamasiɲɛ minnu fɔ ka tɛmɛ, i n’a fɔ ɲɛnamini, nɛ, ani ŋɛɲɛ , olu bɛ bɔ kɛnɛ kan.

Mun de bɛ nin bana in lase mɔgɔ ma?

Mɔgɔ caman b’u yɛrɛ ɲininka ni nin ye bana ye min bɛ sɔrɔ cɛya la. Nka a ka c’a la, o tɛ bana ye min bɛ sɔrɔ cɛya la. A ka c’a la, a bɛ kɛ jɛnɛya dɔ la min bɛ wele ko KIT, o min bɛ sɔrɔ an ka masɔrɔsiraw la.A bɛ sɔrɔ fɛn dɔ Changement random (mutation) fɛ. O jɛnɛya bɛ dɛmɛ ka farikolojɔlifɛn dɔ dilan min bɛ farikolokisɛw falenni kɔlɔsi. O la ni o fɛn caman Changé, mast cellules bɛ daminɛ ka bonya u yɛrɛ ma. Hali ni nin taamasiɲɛ ninnu bɛ se ka ye si hakɛ bɛɛ la, u ka teli ka kɛ mɔgɔkɔrɔbaw la, kɛrɛnkɛrɛnnenya la san 40 ni san 50 cɛ .

Fɛn minnu bɛ kɛ sababu ye ka bana taamasiɲɛw juguya

Nin bana in bɛ mɔgɔ o mɔgɔ la, a taamasiɲɛw tɛ kelen ye. Ani fana, fɛn minnu bɛ bana taamasiɲɛw bila mɔgɔ la, olu bɛ se ka ɲɔgɔn ta mɔgɔ kelen-kelen bɛɛ la. Nka, fɛn minnu bɛ kɛ sababu ye ka mɔgɔw bila ka wale kɛ, olu dɔw bɛ sɔrɔ ja in kɔnɔ min bɛ duguma. A nafa ka bon ka o kow dɔn. A nafa ka bon fana ka aw hakili to a la ko tuma dɔw la, bana taamasiɲɛw bɛ se ka bɔ kɛnɛ kan k’a sɔrɔ kun kɛrɛnkɛrɛnnen si tɛ.

Nin bana in suguya ni a taamasiɲɛ kunbabaw ye jumɛnw ye?

Mastocytosis sistémique suguya belebele duuru bɛ ​​yen. Aw ka dɔgɔtɔrɔ bɛna aw sɛgɛsɛgɛ ka a fɔ aw ye suguya min bɛ aw la.

• Indolent Systemic Mastocytosis (ISM): Nin ye suguya ye min ka teli ka kɛ, wa a man jugu. Bana bɛ taa ɲɛ dɔɔni dɔɔni, a tɛ farikolo yɔrɔw tiɲɛ kosɛbɛ.
• Smoldering Systemic Mastocytosis (SSM): A ka jugu dɔɔni ka tɛmɛ ISM kan. A taamasiɲɛw ka jugu ka tɛmɛ, wa u bɛ se ka farikolo yɔrɔw minɛ waati tɛmɛnen kɔfɛ.
• Mastocytose systémique avec un neoplasme associé hématologique (SM-AHN): O cogo la, mastocytose bɛ taa ni bana wɛrɛ ye min bɛ sɔrɔ joli fɛ (misali la jolidɛsɛ ).
• Mastocytosis systémique aggressive (ASM): Nin suguya in bɛ taa ɲɛ joona, wa a bɛ se ka farikolo yɔrɔw tiɲɛ i n’a fɔ sugunɛ, ɲɛgɛnɛsira ani kolotugudaw.
• Mast Cell Leukemia (MCL): Nin ye suguya ye min man teli ka sɔrɔ ani a ka jugu kosɛbɛ. Masɔrɔsiraw ka ca kolotugudaw ni joli la.

Aw bɛ taamasiɲɛ minnu sɔrɔ, olu bɛ bɔ bana suguya la min bɛ aw la ani aw farikolo la, masɔrɔsiraw bɛ sɔrɔ yɔrɔ min na kosɛbɛ. A taamasiɲɛ minnu ka teli ka ye, olu dɔw filɛ nin ye:

• Nɔgɔ, kurukuru , ɲɛnamini
• Kɔnɔdimi, funu, kɔnɔboli
• Dusukunnata walima fɔɔnɔ
• Kungolodimi ni sɛgɛn
• Dusukun tantanni teliya
• Tansiyɔn jiginni, ɲɛnamini, hakiliɲagami
• Sugunɛ, sɔgɔsɔgɔninjɛ ani sɔgɔsɔgɔninjɛ funu
• Jolidɛsɛ ni jolidɛsɛ cogoyaw
• Kolow fanga dɔgɔyali (Osteoporose) .
• Hakilila ta fan fɛ, cogoyaw i n’a fɔ a ka gɛlɛn ka a hakili to a la, ka to ka jɔrɔ, walima ka degun.

Bana in bɛ se ka sɛgɛsɛgɛ cogo di? (Sɛgɛsɛgɛli) .

Aw ka dɔgɔtɔrɔ bɛna aw ɲininka fɔlɔ aw ka bana taamasiɲɛw la ani ka farikolo sɛgɛsɛgɛli kɛ. O kɔ, u bɛ se ka sɛgɛsɛgɛli caman kɛ walasa ka bana in sɛgɛsɛgɛ:

• Fari biyopisi : Fari yɔrɔ fitini dɔ bɛ bɔ yɔrɔ la min bananen don, ka a lajɛ ni mikroskɔpu ye walasa ka a dɔn ni masɔrɔsiraw caman bɛ yen.
• Kolotuguda biyopisi : Jolilabaarakɛla bɛ pikirijikɛlan finman dɔ kɛ ka aw ka kolotugudaw ta ka a sɛgɛsɛgɛ.
• Joli ni sugunɛ sɛgɛsɛgɛli:Joli jate dafalen (CBC) fana bɛ se ka kɛ ka bana wɛrɛw lajɛ, i n’a fɔ jolidɛsɛ.
• Jɛnɛya sɛgɛsɛgɛli : Joli walima farikolo yɔrɔ dɔ bɛ sɛgɛsɛgɛ walasa ka a dɔn ni fɛn dɔw bɛ KIT jamu la min kofɔra ka tɛmɛ.
• Jaa sɛgɛsɛgɛliw: X-ray, ultrasound ani CT scan bɛ se ka dɛmɛ don ka kolo fanga dɔgɔya ani ka farikolo yɔrɔw funu i n’a fɔ sugunɛ ni sugunɛ.
• Endoskopi walima kolosinsinnan : Tubabu finman min kamera nɔrɔlen don a la, o bɛ kɛ ka kɔnɔbara kɔnɔna walima banakɔtaa sɛgɛsɛgɛ walasa ka a lajɛ ni fɛn dɔ tɛ a la, i n’a fɔ kirinni.

Furakɛliw ye jumɛnw ye?

Dɔgɔtɔrɔ bɛna furakɛli bolodacogo dɔn ka kɛɲɛ ni aw ka bana taamasiɲɛw ye, farikolo yɔrɔ minnu banana, ani bana suguya.

• Histaminiw : Nin fura ninnu bɛ dɛmɛ ka fɛnw kunbɛn i n’a fɔ fariŋɛɲɛ, bilenni, ani kɔnɔdimi.
• Epinephrine : O ye ɔrimɔni ye min bɛ kɛ ni faritanabana jugumanba dɔ kɛra (anaphylaxie).
• Proton Pump Inhibitors : Aw bɛ kɔnɔbara asidi kɔlɔsi ani ka fɛnw dɔgɔya i n’a fɔ kɔnɔboli.
• Mast Cell Stabilizers : Fura minnu bɛ histamine bɔli dabila ka bɔ mast cellules la.
• Stɛroyidiw : A bɛ se ka fari ni ninakili taamasiɲɛw dɛmɛ.
• Furakɛcogo min ɲɛsinnen don a ma: Fura minnu bɛ kɛ sababu ye ka jamu walima farikolojɔlifɛn kɛrɛnkɛrɛnnen dɔ laɲini min sen bɛ bana in na. Ninnu bɛ se ka kɛ mɔgɔ minnu na, bana taamasiɲɛ jugumanw bɛ minnu na.
• Simifura : Nin furakɛli in bɛ se ka kɛ wajibi ye ni bana bɛ ka jɛnsɛn joona ani ka farikolo yɔrɔw tiɲɛ kosɛbɛ.
• Stem Cell Transplant: Furakɛli fɛɛrɛ min bɛ jateminɛ a ka dɔgɔn kosɛbɛ.

Mastocytose systémique, mastosi, farikolojidɛsɛ, farikolojidɛsɛ, anafilakisi, KIT jamu, histamine