Ðe iron sɔ gbɔ ɖe wò ŋutilã me akpaa? Mina míaƒo nu tso Hemochromatosis ŋu!

Ðe ɖeɖi tea ŋuwò le mɔ si mebɔ o nu ɣeaɖewoɣi le susu aɖeke manɔmeea? Ðe wò ƒunukpeƒewo, vevietɔ wò klowo kple afɔbidɛwo, le veve sem, eye wò ŋutigbalẽ dzena ɣie alo akɔbli viea? Zi geɖe la, míeɖea nu siawo ɖa be "alesi míetsina ko." Gake esiawo ate ŋu anye nɔnɔme aɖe si me iron ƒe agbɔsɔsɔ si le míaƒe ŋutilã me dzina ɖe edzi afɔkutɔe ƒe dzesiwo. Woyɔa dɔléle sia le atikewɔwɔ me be Hemochromatosis . Esiae nye nusi ŋu míele nu ƒom tsoe egbea.

Kpuie ko la, nukae nye Hemochromatosis?

Hemochromatosis nye nɔnɔme si me wò ŋutilã ƒoa iron nu ƒu akpa . Ame aɖewo hã yɔnɛ be " gayibɔ ƒe agba si gbɔ eme ."

Zi geɖe la, iron agbɔsɔsɔme si míehiã tso nuɖuɖu si míeɖuna me koe míaƒe ŋutilã xɔana. Gake le amesiwo ŋu ʋumenugbagbeviɣidɔ le gome la, ŋutilãa xɔa iron geɖe wu alesi wòhiã. Kuxiae nye be mɔ aɖeke meli si dzi woato aɖe gayibɔ sia si sɔ gbɔ ɖe ŋutilãa me ɖa o.

Eyata afikae ŋutilãa dzraa gayibɔ sia si sɔ gbɔ ɖo ɖo? Wodzrae ɖo ɖe wò ƒunukpeƒewo, kpakple ŋutinu veviwo abe wò aklã , dzi , ŋutigbalẽ, lãkusi, kple dɔgbo ene me. Le ɣeyiɣi aɖe megbe la, gayibɔ sia si ƒo ƒu la tea nu gblẽm le ŋutinu mawo ŋu. Ne womewɔ atike na ŋutinu siawo o la, ate ŋu adzudzɔ dɔwɔwɔ gɔ̃ hã.

Dɔléle sia ƒomevi vevi evee li.

Woate ŋu ama nɔnɔme sia ɖe hatsotso eve me koŋ.

1. Ʋumenugbagbeviɣidɔ Gbãtɔ: Esiae nye ƒomevi si bɔ wu. Domenyinu mee wònye. Kpuie ko la, hafi dɔléle sia nadze ŋuwò la, ele be nànyi domenyiŋusẽfianu si gblẽ la ƒe dome tso dawò kple fofowò siaa gbɔ. Ne dzila ɖeka koe nyi wò dome la, màxɔ dɔlélea o, gake àte ŋu anye domenyiŋusẽfianu la tsɔla.

2. Secondary Hemochromatosis: Esia dzɔna le susu bubuwo ta. Le kpɔɖeŋu me, nɔnɔme sia ate ŋu ado mo ɖa le amesi hiã be woado ʋu enuenu le nɔnɔme aɖe abe ʋusɔgbɔdɔ sesẽ ene ta.

Nukae hea nɔnɔme sia vɛ?

Na míakpɔ nu siwo tae wòle alea ɖo.

Nusiwo gbɔ domenyiŋusẽfianu tso (Primary Hemochromatosis) .

Domenyiŋusẽfianu aɖe le míaƒe ŋutilã me si woyɔna be `HFE`. Esiae kpɔa ŋusẽ ɖe iron agbɔsɔsɔme si míexɔna le nuɖuɖu si míeɖuna me dzi. Dzɔdzɔmenugbagbevi eve siwo va le `HFE` domenyiŋusẽfianu sia me, siwo nye `C282Y` kple `H63D`, gbɔe domenyiŋusẽfianu ƒe ʋumenugbagbeviɣidɔléla akpa gãtɔ tsona.

Gakpe ɖe eŋu la, domenyiŋusẽfianu bubuwo abe `HJV` kple `HAMP` ƒe tɔtrɔ hã ateŋu ahe dɔléle sia vɛ le ame ʋɛ aɖewo me (anɔ abe 10%-15%). Zi geɖe la, amesiwo ŋu domenyiŋusẽfianu siawo gblẽ nu le la ƒe dzesiwo dzena le woƒe ɖevime.

Atikewɔwɔ ƒe nɔnɔme bubuwo gbɔe wòtsona (Secondary Hemochromatosis) .

Zi geɖe la, ʋudodo enuenu le nɔnɔmewo abe ʋusɔgbɔdɔ sesẽ (abe ʋusɔgbɔdɔ si woyɔna be sickle cell anemia ene) alo ƒumeŋuɖui ƒe dɔmawɔmawɔ nyuie gbɔe wòtsona ƒomevi sia. Iron sɔ gbɔ ɖe ʋumenugbagbevi dzĩ siwo wonana ne èdo ʋu la me. Esi mɔ aɖeke mele ŋutilãa si dzi wòato aɖe gayibɔ sia ɖa o ta la, wodzea ƒoƒo ƒu gɔme.

Azɔ hã, aklã ƒe gbegblẽ, le kpɔɖeŋu me, le aklãdɔ si me ami le ( cirrhosis ) alo aklãdɔléle B alo C si nɔa anyi didi ta, ate ŋu ana iron naƒo ƒu ɖe ŋutilãa me.

Amekawoe le afɔku gã me be woaxɔ dɔléle sia?

Togbɔ be ʋumenugbagbeviɣidɔ ate ŋu axɔ ame sia ame hã la, ame aɖewo ate ŋu adze afɔku wu.

Ðe dzesi siawo hã le ŋuwòa?

Ame siwo ŋu ʋumenugbagbeviɣidɔ le la dometɔ siwo ade afã mekpɔa dzesi aɖeke o. Zi geɖe la, ŋutsuwo ƒe dzesiwo dzena le woƒe ƒe 30 va ɖo ƒe 50 dome, gake zi geɖe la, nyɔnuwo ya ƒe dzesiwo dzena le woƒe ƒe 50 xɔxɔ alo le woƒe dzinukpɔkpɔ megbe.

Aleke nèwɔ kpɔ esia, Ðɔkta?

Esi wònye be woate ŋu akpɔ dzesi siawo le dɔléle bubuwo me ta la, ate ŋu asesẽ ɣeaɖewoɣi be woakpɔ wo. Wò ɖɔkta abia wò ƒomea ƒe atikewɔwɔ ŋutinya eye wòado wò ŋutilã hã kpɔ.

Tsɔ kpe ɖe eŋu la, woate ŋu awɔ dodokpɔ siawo:

• Ʋudodokpɔ: Wowɔa dodokpɔ vevi eve le afisia.
• Transferrin Saturation: Esia dzidzea iron agbɔsɔsɔme si bla ɖe protein (transferrin) si tsɔa iron yia ʋu me ŋu.
• Serum Ferritin: Esia dzidzea protein (ferritin) si dzraa iron ɖo ɖe ʋua me ƒe agbɔsɔsɔme.

Ne dodokpɔ siawo ɖee fia be iron sɔ gbɔ ɖe mewò la, wò ɖɔkta ate ŋu awɔ domenyiŋusẽfianu ƒe dodokpɔ hã atsɔ akpɔe ɖa be domenyiŋusẽfianu si nana ʋumenugbagbeviɣidɔ le ŋuwò hã.

• Aklãdɔ: Ðɔktaa ɖea lãkusi sue aɖe tso aklãa me hedoa ekpɔ le nusuekpɔmɔ̃ me be yeakpɔe ɖa be nu gblẽ le aklãa ŋu hã.

• MRI scan: Esia ate ŋu aɖe wò ŋutinuwo ƒe nɔnɔmetata siwo me kɔ eye woakpɔe ɖa be iron le wo me hã.

Nukawoe nye atikewɔmɔnuawo?

Ne Primary Hemochromatosis le ŋuwò la, atikewɔwɔa le bɔbɔe ŋutɔ. Ebia be nàɖe ʋu le wò ŋutilã me le ɖoɖowɔɖi aɖe koŋ dzi. Woyɔa esia be Phlebotomy.

Phlebotomy ƒe dɔwɔwɔ

Esia sɔ kple ʋudodo. Ðɔkta alo dɔnɔdzikpɔla si xɔ hehe dea aŋe ɖe ʋuka aɖe me le wò alɔnu eye wòhea ʋu yia ʋukotoku me.

• Atikewɔwɔ gbãtɔ: Le gɔmedzedzea me la, ahiã be nàyi kɔdzi zi ɖeka alo zi eve le kwasiɖa me be woaɖe ʋu vaseɖe esime wò iron ƒe agbɔsɔsɔ atrɔ ava nɔ abe tsã ene. Esia ate ŋu axɔ ɣleti geɖe alo ƒe ɖeka.
• Atikewɔwɔ si woatsɔ alé be na ame: Ne iron ƒe agbɔsɔsɔ gaɖo eƒe nɔnɔme si sɔ me ko la, woɖea ʋudodo zi gbɔ zi geɖe dzi kpɔtɔna, eye zi geɖe la, va ɖoa zi eve va ɖo zi ene le ƒea me.

Atikewo zazã (Chelation Therapy) .

Ne ʋumenugbagbeviɣidɔ evelia le ŋuwò, alo ne wò ʋukawo mesẽ ale gbegbe be woate ŋu axɔ ʋu o la, wò ɖɔkta ate ŋu aŋlɔ atike aɖe si woyɔna be `Chelation Therapy.` Le esia me la, wonaa atike aɖe wò si kpena ɖe wò ŋutilã ŋu wòɖea iron si sɔ gbɔ wu ɖa to wò aɖuɖɔ kple aɖuɖɔ me.

Ðe woate ŋu akpɔ nɔnɔme sia gbɔ le aƒemea?

Zi geɖe la, mehiã be amesi wole ʋukawo ɖeɖeɖa ƒe atike wɔm na nawɔ tɔtrɔ gã aɖeke le eƒe nuɖuɖu ŋu o, elabena atikewɔwɔa ŋutɔ kpɔa iron ƒe agbɔsɔsɔ dzi. Gake àte ŋu awɔ nu siwo gbɔna be nàɖe kuxi siwo ate ŋu ado mo ɖa dzi akpɔtɔ:

• Ƒo asa na ahanono keŋkeŋ. Aha gblẽa nu le aklãa ŋu, si wɔnɛ be wòzua afɔku gã aɖe le dɔléle sia ŋu.
• Ƒo asa na tɔmelã ƒuƒu alo ƒumelã ƒuƒu ɖuɖu. Dɔlékui siwo le esiawo me ate ŋu ahe dɔlékui sesẽwo vɛ na amesiwo me iron sɔ gbɔ ɖo.
• Ƒo asa na vitamin C ƒe kpeɖeŋutɔ nono. Gake kuxi aɖeke mele atikutsetse kple amagbe siwo me vitamin C le ɖuɖu me o.
• Ƒo asa na iron-tike alo vitamin geɖe siwo me iron le nono.
• Ƒo asa na ŋdi me nuku siwo me gayibɔ le.