Ðe nènye amesi ŋu nulɔdɔ le zi geɖea? Ðe wòdzea ʋuʋu gɔme le gbɔgbɔ si me ke le megbea, ɖe wò lãme ʋuʋuna le nuɖuɖu ɖuɖu vɔ megbea, alo ɖeko nèƒoa wò ŋutilã ɣeaɖewoɣia? Egbea míele nu ƒom tso asrafo sue aɖe si le vevie ŋutɔ si le megbe na nusiawo katã ŋu. Ðewohĩ èkpɔ nya ‘Basophils’ le wò ʋu ŋuti nyatakakawo dometɔ ɖeka me, si fia be le ‘Ʋu Xexlẽme Blibo’ me. Eyata nukae nye basophil siawo ? Nukatae míaƒe ŋutilã hiã wo? Mina míaƒo nu tso esia ŋu le mɔ bɔbɔe aɖe si gɔme sese le bɔbɔe nu.
Nuka tututue nye basophil?
Kpuie ko la, basophils nye ʋumenugbagbevi ɣi ƒomevi aɖe (`White Blood Cell` - WBC) le míaƒe ʋu me. Tsɔe be míaƒe ŋutilã le abe dukɔ ene. Ekema ʋumenugbagbevi ɣiwoe nye dukɔ sia takpɔha. Ŋusẽ vovovowo le ŋusẽ sia me. Eyata, ʋumenugbagbevi ɣi ƒomevi atɔ̃e li. Basophils ye nye esiwo mesɔ gbɔ boo o le ƒomevi atɔ̃awo dome, si fia be wonye ŋusẽ si mebɔ kura o.
Basophil lãmenugbagbevi siawo me la, lãmenugbagbevi suesuesuewo le wo me. Atike vevi aɖe ŋutɔ si woyɔna be histamine yɔa nuku siawo me fũ. Histamine siae nana ŋku siwo le ʋuʋum, siwo biã, kple ŋɔti me tsi si le dodom le ŋuwò ne nulɔdɔ aɖe le ŋuwò. Basophils kpena ɖe mía ŋu hã be míakpɔ míaƒe ŋutilã ta tso dɔlékuiwo si me eye wodaa abiwo .
Basophils ƒe dzɔdzɔme kple nɔnɔmewo
Basophils ƒe nɔnɔme siawo le vevie ŋutɔ na ɖɔktawo be woate ŋu anya dɔléle aɖewo. Mina míalé ŋku ɖe asrafo sue sia ŋuti nyatakaka aɖewo ŋu.
| Ŋutinu | Nuɖᴐɖᴐ |
|---|---|
| Lolome | Esiawo le sue ŋutɔ, woƒe lolome anɔ abe micrometer 5-10 (μm). |
| Dzedzeme kple amadede | Ne wotsɔ amadede tɔxɛ aɖe (Wright-Giemsa ƒe amadede) de eme la, lãmenugbagbevi siwo me histamine yɔ fũu la dzena abe aŋutiɖiɖi dzẽ ene. Woate ŋu ade dzesi nusiawo bɔbɔe le nusuekpɔmɔ̃ me. |
| Lãmenugbagbeviwo ƒe titina (Nucleus) . | Zi geɖe la, lãmenugbagbevi la ƒe titina ƒe nɔnɔme nɔa abe ŋɔŋlɔdzesi ‘S’ ene. |
| Agbenɔƒe kple vidzidzi | Wowɔa basophils le ƒumeŋuɖui si le míaƒe ƒuwo me la me. Ne wonya wɔ wo le afima ko la, anɔ agbe abe gaƒoƒo 60 ene le ʋua me yiyi vɔ megbe. |
| Dzesi Siwo Le Anyigba Dzi | Protein tɔxɛ aɖewo siwo le lãmenugbagbevi siawo ƒe anyime (abe `CD-123`, `CD-193`) kpena ɖe ɖɔktawo ŋu wokpɔa dɔlélewo abe ʋumenugbagbeviɣidɔ aɖewo (`Leukemia`) ene. |
Subɔsubɔdɔ kae basophils wɔna na míaƒe ŋutilã?
Dɔ vevitɔ si basophils wɔnae nye be wòaɖe histamine si ŋu míeƒo nu tsoe va yi la ɖa. Gake tsɔ kpe ɖe eŋu la, lãmenugbagbevi sue siawo wɔa dɔ gã aɖe na míaƒe ŋutilã.
- Takpɔkpɔ tso Nulɔdɔlékuiwo Me : Ne nuwo abe ke kple aŋɔ ene ge ɖe ŋutilãa me la, ewɔa avu kpli wo.
- Avuwɔwɔ kple dɔlékuiwo: Esiawo wɔa dɔ le dɔlékuiwo ƒe dɔlékuiwo abe pinworms ene me.
- Abi ƒe dɔyɔyɔ : Ekpena ɖe abi ƒe dɔyɔyɔ ŋu.
- Mɔxexe ɖe ʋu ƒe sisi nu: Lãmenugbagbevi siawo hã ɖea atike aɖe si woyɔna be heparin, si kpena ɖe ame ŋu be ʋuka siwo melɔ̃ o la ƒuna.
Ƒomedodo si le nulɔdɔwo kple basophils dome
Kpɔe ɖa le susu me be nudzodzoe aɖe le wò asi ɖum. Le ɣeyiɣi aɖe megbe la, teƒea biãna, vuvuna, eye wònɔa ʋuʋum ŋutɔ, alo? Nu mae histamine, si dona le basophils me la wɔna.
Nusi histamine wɔnae nye be ʋu sina yia teƒea dzina ɖe edzi. Emegbe esia hea ʋu geɖe vaa teƒea, "klɔa"e doa goe, si kpena ɖe ame ŋu be wòakɔ nulɔdɔlékui la ɖa. Le nyateƒe me la, abi kple abi sia nye dɔyɔyɔ ƒe akpa aɖe.
Ne nulɔdɔ aɖe ge ɖe amesi ŋu nulɔdɔ le ƒe ŋutilã me la, dɔlélenutsiŋutete wɔa dɔlékuiwutike ƒomevi aɖe si woyɔna be Immunoglobulin E (IgE). IgE sia yia eye wòléna ɖe nusi nana ŋutilãa mewɔa nu ɖe ame ŋu o la ŋu. Emegbe basophils va dzea IgE-allergen complex sia dzi, eye woɖea histamine siwo katã le wo me la ɖe go. Ɣemaɣie nèkpɔa nulɔdɔ ƒe dzesiwo.
- No me tsi si le dodom, aɖuɖɔɖɔɖɔ
- Ŋku dzĩ siwo le ʋuʋum
- Kɔ ƒe ʋuʋu
- Ŋutilã ƒe ʋuʋudedi, ʋuʋudedi
- Yagbɔgbɔ sesẽ na asrãdɔlélawo
Aleke nèwɔna léa ŋku ɖe basophil ƒe agbɔsɔsɔ si le wò ʋu me ŋu?
Ne wò ɖɔkta de se na wò be woado `Ʋu Xexlẽme Blibo (CBC)` kpɔ, alo abe alesi míeyɔnae ene la, `ʋu ƒe xexlẽme blibo` la, woaŋlɔ basophil xexlẽme hã ɖe nyatakaka ma dzi. Woate ŋu ade esia nyatakakaa me le mɔ eve nu.
1. Abe alafa memamã (%) ene: Ʋumenugbagbevi ɣiwo katã ƒe alafa memamã nenie nye basophils? Zi geɖe la, esia nyea asixɔxɔ sue aɖe ŋutɔ, anɔ abe 0.5% - 1% ene.
2. Xexlẽme Blibo: Basophils ƒe xexlẽme ŋutɔŋutɔ le ʋu mililita ɖeka me.
Nu vevitɔ enye be nàtsɔ wò asixɔxɔwo asɔ kple ‘Normal Range’ alo ‘Reference Range’ ƒe kɔlam si le wò dodokpɔxɔ ƒe nyatakaka me, elabena asixɔxɔ siawo siwo sɔ ate ŋu ato vovo vie le mɔ̃ si wozã le dodokpɔxɔ ɖesiaɖe me nu.
| Gbadzaa | Gɔmeɖeɖe |
|---|---|
| Xexlẽme si sɔ | Ʋumenugbagbevi ɣiwo ƒe 0.5% - 2% dome. Zi geɖe la, asixɔxɔ bliboa ate ŋu atso 0.01 x 109/L va ɖo 0.08 x 109/L. |
| Agbɔsɔsɔ si dzi ɖe edzi (Basophilia) . | Basophil ƒe agbɔsɔsɔ sɔ gbɔ wu alesi wòle dzɔdzɔmee. |
| Agbɔsɔsɔme si le bɔbɔe (Basopenia) . | Basophil ƒe agbɔsɔsɔ si le ɖiɖim ɖe anyi wu alesi wòle. |
Ðe basophils (basophilia) ƒe dzidziɖedzi nye afɔkua?
Woyɔa basophil ƒe agbɔsɔsɔ ƒe dzidziɖedzi le atikewɔwɔ me be ``Basophilia.'' Susu geɖewo ateŋu anɔ esia ta.
- Nulɔdɔwo: Nulɔdɔwo abe nuɖuɖu, atike, ke, kple bubuawo ene.
- Dɔlékuiwo: Dɔlékui aɖewo abe koklozi kple dzamezã ene.
- Lãmetsiŋusẽ ƒe kuxiwo: Lãmetsiŋusẽ si mebɔ o (`Hypothyroidism`).
- Ŋutilãmedɔlélewo: Ŋutilã ƒe nɔnɔme siwo le abe eczema ene abe atopic dermatitis ene.
- Ʋumedɔlélewo: Nɔnɔmewo abe polycythemia vera ene.
- Kansa ƒe nɔnɔme aɖewo: Ʋu me kansa abe chronic myeloid leukemia (CML) ene.
Mègavɔ̃ le xexlẽdzesi sia ta o. Zi geɖe la, basophil ƒe xexlẽme si dzi ɖe edzi vie ate ŋu atso nane si le bɔbɔe abe nulɔdɔ si bɔ ene gbɔ. Gake ele be nàgblẽe ɖe wò ɖɔkta si me be wòakpɔ nusi tututu gbɔ wòtso. Awɔ dodokpɔ bubuwo ne ehiã be woatsɔ aɖo kpe nusi gbɔ wòtso dzi.
Nukae nye basopenia?
Woyɔa basophil ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ be ``Basopenia.`` Esia mebɔ vie wu ``Basophilia.`` Esia ateŋu atso susu geɖewo hã gbɔ.
- Dɔlékui aɖewo.
- Lãmetsiŋusẽ si woyɔna be thyroid hormone (`Hyperthyroidism`) ƒe wɔwɔ fũ akpa.
- Nulɔdɔ sesẽ aɖe si dzɔna enumake (`Anaphylaxis`).
- Dɔlélenutsiŋutete ƒe dɔléle aɖewo, le kpɔɖeŋu me `Systemic Lupus Erythematosus (SLE)`.
Basophils ƒe ɖiɖi ate ŋu akpɔ ŋusẽ ɖe míaƒe ŋutilã ƒe abi ƒe dɔyɔyɔ hã dzi.
Ɣekaɣie wòle be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo enumake
Togbɔ be afɔku mele nulɔdɔ si sɔ me o hã la, ɣeaɖewoɣi dɔlélenutsiŋutete te ŋu wɔa nu wògbɔa eme. Woyɔa esia be `Anaphylaxis`.
Anaphylaxis nye atikewɔwɔ kpata si ate ŋu ade ame ƒe agbe afɔku me. Ne wò alo ame bubu aɖe kpɔ dzesi siwo gbɔna la dometɔ aɖe la, yi kɔdzi ƒe dɔwɔƒe si te ɖe ŋuwò kpata (ETU) enumake.
- Nuyi, aɖe, alo mo ƒe vuvu
- Yagbɔgbɔ sesẽ
- Nu mimi sesẽ
- Ŋutilã ƒe ʋuʋu alo biã le ŋutilã bliboa me
- Dɔgbo ƒe veve, ʋuʋudedi, alo aɖuɖɔtoe
- Akɔta ƒe tete alo ʋuʋudedi ƒe gbeɖiɖi
- Sese le eɖokui me be taɖuame alo yeƒe tagbɔ le gbegblẽm
Le ɣeyiɣi siawo tɔgbe me la, ele vevie ŋutɔ be míagatsi dzodzodzoe ahadi atike enumake o.
Gbedasi si Wotsɔ Yi Aƒeme
- Basophils nye ʋumenugbagbevi ɣi ƒomevi vevi aɖe le míaƒe dɔlélenutsiŋutete me si wɔa avu kple nulɔdɔwo kple dɔlékui siwo tsoa dɔlékuiwo gbɔ.
- Histamine, si woɖena doa goe, gbɔe nusiwo ŋu nulɔdɔ le ƒe dzesi geɖe, abe ʋuʋudedi kple vuvu ene, tsona.
- Ne basophil ƒe agbɔsɔsɔ si le wò ʋu me le agbɔsɔsɔ si sɔ me la, mègatsi dzodzodzoe eye nàƒo nu kple wò ɖɔkta o. Zi geɖe la, nusi gbɔ wòtso ate ŋu anye nu bɔbɔe aɖe.
- Ne èkpɔ nulɔdɔ ƒe dzesi sesẽwo abe gbɔgbɔ sesẽ kple mo ƒe vuvu ene la, ke enye nusi dzɔ kpata. Yi kɔdzi aɖe ƒe Dɔwɔƒe si Kpɔa Nudzɔdzɔ Kpatawo Gbɔ (ETU) enumake.
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Womeɖo nya aɖeke ɖe amewo haɖe o. Tsɔ wò nyaŋuɖoɖo kpe ɖe afisia zi gbãtɔ.
Tsɔ wò nyaŋuɖoɖo kpee