Inā ua ʻike ʻia ʻoe a i ʻole kekahi āu i ʻike ai me ka maʻi ʻaʻai umauma, ua lohe paha ʻoe i ka huaʻōlelo 'hormone therapy'. ʻO ka lohe ʻana i kēia inoa hiki iā ʻoe ke makaʻu iki a hoihoi. He aha ke ʻano maoli? He mea weliweli anei? He aha kāna hana? E kamaʻilio kākou e pili ana i kēia mau mea a pau ma ke ʻano maʻalahi a aloha hoʻi i kēia lā.
He aha kēia ʻano hoʻōla hormone?
I ka ʻōlelo maʻalahi, he lāʻau lapaʻau maikaʻi loa ka lāʻau lapaʻau hormone no kekahi mau ʻano maʻi ʻaʻai umauma. Eia naʻe, ʻaʻole ia e hāʻawi ʻia no nā maʻi ʻaʻai umauma āpau. He mea nui loa ia no nā maʻi ʻaʻai i loaʻa ka hormone receptor-positive (HR+) .
E noʻonoʻo e pili ana i ia mea, aia ʻelua ʻano hormones i hana maoli ʻia i loko o ko kākou kino i kapa ʻia ʻo Estrogen a me Progesterone. Ua like kekahi mau hunaola maʻi umauma me kahi mea kanu liʻiliʻi. E like me ka mea kanu e pono ai ka wai, pono kēia mau hunaola maʻi i kēia mau hormones ʻelua e ulu a laha. Kāhea mākou i kēia he maʻi HR+. Ma ke ʻano maʻamau, ʻelua o ʻekolu mau maʻi maʻi umauma i loaʻa i kēia ʻano maʻi.
Ua ʻike paha ʻoe i nā mea e like me kēia ma kāu hōʻike maʻi kanesa:
- Loaʻa ka loaʻa ʻana o ka estrogen (ER+)
- Loaʻa ka progesterone maikaʻi (PR+)
Hiki i ka maʻi kanesa ke maikaʻi no kekahi a i ʻole nā mea ʻelua. ʻO ER+ ke ʻano maʻamau.
No laila, he maʻalahi loa ka hana a kēia lāʻau lapaʻau hormone. Hana ia ma nā ʻano nui ʻelua:
1. Ke ālai nei ia i nā hormones (estrogen a me progesterone) e pono ai nā hunaola kanesa. Ua like ia me ke ālai ʻana i ka paipu wai e hoʻolako ana i ka mea kanu.
2. Hoʻemi i nā pae estrogen i loko o ke kino. Hoʻonele kēia i nā hunaola kanesa i ka "meaʻai" e pono ai lākou e ulu a hoʻōki iā lākou mai ka ulu ʻana.
ʻO ka mea nui, ʻokoʻa loa ka lāʻau lapaʻau hormone no ka maʻi ʻaʻai umauma mai ka lāʻau lapaʻau hormone no nā hōʻailona menopausal, kahi e hana ai ma ka hoʻonui ʻana i nā pae hormone. Hana ka lāʻau lapaʻau kanesa i ka ʻaoʻao ʻē aʻe.
No ke aha i hāʻawi ʻia ai kēia lāʻau hormone?
Hoʻomaopopo nā kauka Oncology i kēia lāʻau lapaʻau i nā kūlana like ʻole.
- No ka hōʻemi ʻana i ka pilikia o ka maʻi kanesa: Hāʻawi ʻia kēia lāʻau lapaʻau i ka poʻe i loaʻa ka pilikia nui o ka loaʻa ʻana o ka maʻi kanesa o ka umauma, no ka laʻana, ka poʻe me nā hoʻololi genetic e like me `BRCA1` a me `BRCA2`, e pale aku i ka ulu ʻana o ka maʻi kanesa.
- I ke ʻano o DCIS: Kāohi i ka ulu ʻana o ka maʻi ʻaʻai umauma mua i kapa ʻia ʻo `Ductal Carcinoma In Situ (DCIS).`
- Ma mua o ke ʻoki kino (Neoadjuvant Therapy):Hāʻawi ʻia kēia lāʻau ma mua o ke ʻoki ʻana e hoʻēmi i ka puʻupuʻu a maʻalahi i ke ʻoki ʻana.
- Lapaʻau Hoʻohui: ʻO kēia ke ʻano lapaʻau maʻamau. Hāʻawi ʻia ma hope o ke ʻoki ʻana e wehe i ke kanesa, e pale i ka hoʻi hou ʻana mai o ke kanesa a i ʻole e pale i ka ulu ʻana o ke kanesa ma ka umauma ʻē aʻe.
- Ke pālahalaha ke kanesa (Metastatic Breast Cancer): Inā ua pālahalaha ke kanesa i nā ʻāpana ʻē aʻe o ke kino, hoʻohana ʻia kēia lāʻau lapaʻau e kāohi i ka ulu ʻana o kēlā mau cell.
He aha nā ʻano nui o ka lāʻau lapaʻau hormone?
Aia kekahi mau ʻano lāʻau lapaʻau hormone. Na kāu kauka e hoʻoholo i ka lāʻau lapaʻau maikaʻi loa iā ʻoe ma muli o nā mea e like me kou makahiki, inā ua hala ʻoe i ka menopause, a me ke ʻano o ke kanesa. E nānā kākou i nā ʻano nui.
| ʻAno o ka Lapaʻau | Pehea e hana ai a me nā laʻana |
|---|---|
| Nā mea pale ʻala | Hāʻawi nui ʻia kēia mau mea i nā wahine post-menopausal . Hoʻōki lākou i ke kino mai ka hana ʻana i ka estrogen. Nā laʻana: Letrozole, Anastrozole, Exemestane. |
| Nā SERM (Nā Modulators Receptor Estrogen Koho) | Hoʻopau kēia mau lāʻau i ka pilina o ka hormone estrogen i nā hunaola kanesa. Hiki ke hoʻohana ʻia e nā wahine ma mua a me ka postmenopausal . ʻO ka lāʻau i hoʻohana pinepine ʻia ʻo Tamoxifen . |
| Ka Hoʻopau ʻana i ka Hana Ovarian | Hāʻawi ʻia kēia mau mea i nā wahine ma mua o ka menopause . Hoʻōki lākou i ka hana ʻana o ka estrogen mai nā ovaries no kekahi manawa. Hāʻawi pinepine ʻia kēia mau mea ma ke ʻano he inikini. Nā laʻana: Goserelin, Leuprolide. |
| Nā SERD (Nā Hoʻohaʻahaʻa Hoʻokipa Estrogen Koho) | Ua like kēia me nā SERM, akā ʻoi aku ka ikaika o ka pale ʻana a me ka luku ʻana i nā mea loaʻa estrogen. Laʻana: Fulvestrant. |
Pehea e loaʻa ai kēia lāʻau lapaʻau?
ʻO ka hapa pinepine, hāʻawi ʻia kēia lāʻau lapaʻau ma ke ʻano he pila āu e lawe ai i kēlā me kēia lā. Loaʻa kekahi mau lāʻau lapaʻau ma ke ʻano he wai. ʻO kekahi, e like me nā lāʻau lapaʻau e hoʻōki i ka hana ʻana o nā ovaries, hāʻawi ʻia ma ke ʻano he inikini ma ke keʻena o kāu kauka i hoʻokahi manawa i ka mahina. Ma muli o kou kūlana, pono paha e lawe ʻia kēia lāʻau lapaʻau no ka manawa lōʻihi, e like me 5 a 10 mau makahiki paha .
Aia kekahi mau hopena ʻaoʻao i kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau a pau, hiki ke loaʻa kekahi mau hopena ʻaoʻao me kēia lāʻau lapaʻau. Eia naʻe , ʻaʻole loaʻa i nā kānaka a pau, a ʻaʻole like ka manaʻo o nā kānaka a pau . ʻAʻole paha e ʻike kekahi poʻe i kekahi ʻeha. ʻO nā hopena ʻaoʻao maʻamau:
- Manaʻo luhi a pau loa.
- Nā ʻā wela.
- ʻEha a ʻoʻoleʻa paha nā hono a me nā ʻiʻo.
- Ua emi ka makemake i ka moekolohe.
- Nā loli pinepine o ka naʻau.
- Ka luaʻi a me ka luaʻi.
- Maloʻo ka ʻōpū.
- Piʻi ke kaumaha.
Inā ʻoe e ʻike nei i kekahi o kēia mau ʻano ʻeha, mai hilahila a makaʻu paha e kamaʻilio me kāu kauka . Aia nā ala a me nā lāʻau lapaʻau e hiki ke kōkua i ka hoʻokele ʻana i nā hopena ʻaoʻao he nui. No laila, mai ʻeha hoʻokahi.
Nā pono a me ka holomua o ka lāʻau lapaʻau hormone
ʻO kekahi o nā pono nui o kēia lāʻau lapaʻau, ʻo ia ke kuhikuhi ʻana i ke ʻano maʻamau o ka maʻi ʻaʻai umauma (ER+). Eia kekahi, hiki ke hāʻawi ʻia kēia lāʻau lapaʻau me nā lāʻau lapaʻau ʻē aʻe e like me ka chemotherapy a me ka lāʻau lapaʻau i kuhikuhi ʻia.
Ua hōʻike maopopo ʻia ka noiʻi e hōʻemi nui ana ka lāʻau lapaʻau hormone i ka pilikia o ka hoʻi hou ʻana o ka maʻi kanesa a hoʻolōʻihi i ke ola o nā maʻi, e lilo ia i koho lapaʻau holomua a koʻikoʻi loa.
He ʻoi aku ka maikaʻi o ka chemotherapy a i ʻole ka hormone therapy?
Ua like kēia me ka nīnau ʻana, "ʻO wai ka mea ʻoi aku ka maikaʻi, he screwdriver a he hāmare paha?" He ʻelua mau mea hana like ʻole i hoʻohana ʻia no nā kumu like ʻole. He lāʻau lapaʻau ikaika ka Chemotherapy e pepehi ana i nā cell e māhele wikiwiki ana. ʻO ka hormone therapy kahi lāʻau lapaʻau e kuhikuhi wale ana i nā cell kanesa e hilinaʻi ana i ka hormone. I kekahi manawa pono paha ʻoe i nā mea ʻelua, a i kekahi manawa hoʻokahi wale nō kāu e pono ai. Na kāu kauka e hoʻoholo i ka mea maikaʻi loa iā ʻoe.
He aha inā ʻaʻole wau makemake i kēia lāʻau lapaʻau?
He nīnau koʻikoʻi loa kēia. E hoʻomanaʻo, he mea nui loa kou mau makemake a me kou mau manaʻo i ka wā e pili ana i ka mālama ʻana. E paipai kāu kauka i kahi hoʻolālā mālama e pili ana i nā mea āpau mai ke ʻano o ka maʻi kanesa āu, kou olakino holoʻokoʻa, kou nohona, a me kāu mau makemake.
Inā he mau makaʻu, kānalua, a makemake ʻole paha ʻoe e pili ana i ka lāʻau lapaʻau hormone, mai kānalua e kamaʻilio ākea me kāu kauka e pili ana i ia mea . ʻO ka mea nui loa, ʻo ia ke kamaʻilio e pili ana i nā pono a me nā hemahema o ka lāʻau lapaʻau, ka mea e hana ai inā he mau hopena ʻaoʻao, a inā he mau koho ʻē aʻe, a hana i kahi hoʻoholo naʻauao e kūpono iā ʻoe.
Leka Lawe-Home
- He lāʻau lapaʻau kūpono loa ka hormone therapy no ka maʻi ʻaʻai umauma e pili ana i ka hormone (estrogen, progesterone) (HR+).
- Hoʻopili kēia i nā hunaola kanesa mai ka loaʻa ʻana o nā hormones a i ʻole e hōʻemi ana i nā pae hormone i loko o ke kino.
- Hiki ke hoʻohana ʻia kēia ma mua a ma hope paha o ke ʻoki ʻana e hōʻemi i ka pilikia o ka maʻi kanesa a i ʻole e kāohi i ka maʻi kanesa i laha.
- Hiki ke loaʻa nā hopena ʻaoʻao, akā hiki ke mālama ʻia. He mea nui e kamaʻilio me kāu kauka e pili ana i kekahi ʻeha.
- E kūkākūkā me kāu kauka i kekahi mau nīnau a hopohopo paha āu e pili ana i ka mālama ʻana a e hana pū i ka hoʻoholo maikaʻi loa.
💬 Comments (0)
ʻAʻohe manaʻo i kau ʻia. Hoʻohui i kāu manaʻo ma ʻaneʻi no ka manawa mua.
Hoʻohui i kāu manaʻo