Hāʻawi ʻo Jynarque (Tolvaptan) i ka hōʻoluʻolu no ADPKD, kahi maʻi puʻupaʻa e hoʻoulu ai i nā cysts i loko o nā puʻupaʻa

Ua haʻi aku anei kāu kauka iā ʻoe a i ʻole kekahi o kou ʻohana he maʻi kou e hoʻoulu ai i nā cysts piha i ka wai e hana i loko o kou mau puʻupaʻa? Ua ʻike ʻia kēia ma ke ʻano lapaʻau ʻo 'Autosomal Dominant Polycystic kidney disease ', a i ʻole ADPKD no ka pōkole. He mea maʻamau ke manaʻo iki i ka makaʻu ke lohe ʻoe i kēia, no ka mea, i ka hala ʻana o ka manawa, hiki i kēia ke alakaʻi i ka hāʻule ʻana o ka puʻupaʻa. Akā, mai hopohopo. Aia nā lāʻau lapaʻau e hiki ke hoʻolohi i ke ala o kēia maʻi a kōkua i ka pale ʻana i kou mau puʻupaʻa. I kēia lā, ke kamaʻilio nei mākou e pili ana iā Jynarque , ʻo ia wale nō ka lāʻau i ʻae ʻia no kēia maʻi.

Pehea e kōkua ai kēia lāʻau lapaʻau ʻo Jynarque i nā poʻe maʻi ADPKD?

I ka ʻōlelo maʻalahi, ʻo ADPKD kahi maʻi genetic i hoʻoili ʻia mai kēlā hanauna a i kēia hanauna . He ʻano kēia kahi e nui ai nā cysts i piha i ka wai (cysts) i loko o nā puʻupaʻa. I ka hala ʻana o ka manawa, ulu kēia mau cysts, e hoʻololi ana i ke ʻano o nā puʻupaʻa a lilo i mea nui loa ma mua o ka maʻamau. I ka hopena, ʻaʻole hiki i nā puʻupaʻa ke hana i kā lākou hana o ka kānana pono ʻana i ke koko. ʻO ka hapa nui, ʻaʻole ʻike ʻia kēia mau hōʻailona i nā poʻe ʻōpio, akā ma waena o 30 a me 50 mau makahiki. ʻO kahi hōʻailona maʻamau ka koko kiʻekiʻe . Hiki ke loaʻa ka ʻeha i nā puʻupaʻa. Hiki ke hana ʻia kēia e nā maʻi i loko o nā puʻupaʻa a i ʻole ke ala urinary, nā cysts i haki, a i ʻole nā ​​​​pōhaku puʻupaʻa. ʻO ka hapa nui o nā mea me ADPKD e loaʻa i ka maʻi puʻupaʻa mau loa (CKD). He ʻano kēia e lilo mālie i mea ʻino. E nānā kākou i nā pae. ʻO ka pahuhopu nui o ka mālama ʻana iā ADPKD, ʻo ia ka hoʻolohi ʻana i ka hōʻino ʻana i nā puʻupaʻa i ka hiki. ʻO kahi ala e hana ai i kēia, ʻo ia ke kāohi i kou koko kiʻekiʻe. ʻO kekahi, ʻo ka inu ʻana i ka wai he nui i ka lā a kaupalena i kāu lawe ʻana i ka caffeine (kī, kofe). Eia kekahi, hiki i kāu kauka ke paipai i nā hoʻololi ʻana i ke ʻano o ka nohona e like me ka hoʻoikaika kino, ka hōʻemi ʻana i ka paʻakai i kāu meaʻai, a me ka haʻalele ʻana i ka puhipaka.

ʻAʻole anei kūpono kēia lāʻau lapaʻau no nā kānaka a pau?

ʻAe, ʻaʻole kūpono ʻo Jynarque no nā maʻi āpau. He mea nui e haʻi i kāu kauka e pili ana i kou mau kūlana olakino i hala a me kēia manawa , ʻoiai hoʻi:

• Inā he mau pilikia kou i ke akepaʻa.
• Inā he haʻahaʻa a kiʻekiʻe paha kou mau pae sodium i loko o kou koko.
• Inā pilikia ʻoe i ka mimi ʻana (e like me nā pōhaku puʻupaʻa , ke ālai ʻana o ke ala mimi).
• Inā ʻaʻole ʻoe e make wai a pilikia paha i ka inu wai i ka lā a pau.

He mea nui loa ke kamaʻilio ʻana me kāu kauka e pili ana i nā mea e like me kēia no kou palekana.

Pehea e hoʻohana ai i ka lāʻau lapaʻau?

He pila ʻo Jynarque i lawe ʻia i ʻelua manawa i ka lā. Hiki ke lawe ʻia ma mua a ma hope paha o ka ʻai ʻana. He mea nui loa ka manawa e lawe ai i kēia. Ke hoʻomaka ʻoe e lawe i ka lāʻau lapaʻau, e hāʻawi kāu kauka iā ʻoe i kahi mahele haʻahaʻa. Inā ʻaʻohe ou pilikia nui no 1-2 mau pule, e hoʻonui iki lākou i ka mahele. Ma hope o kēlā, inā ʻaʻohe ou pilikia, hiki iā ʻoe ke hoʻonui hou i ka mahele. Inā ʻoe e poina i kahi mahele lāʻau, mai lawe. E hōʻalo i ka mahele lāʻau i poina a lawe i kāu mahele lāʻau aʻe i ka manawa i hoʻonohonoho ʻia. He mea nui e hahai pololei i ka papa kuhikuhi, i kou ala ʻana i ke kakahiaka a ma hope o 8 mau hola. He manaʻo maikaʻi e hoʻonohonoho i kahi alarm ma kāu kelepona e hoʻomanaʻo i ka lua o ka mahele lāʻau.

He aha ka ʻōlelo a nā hoʻokolohua e pili ana i ka holomua o kēia lāʻau lapaʻau?

Ua mālama ʻia ʻelua mau haʻawina nui e nānā i ka palekana a me ka pono o ka lāʻau lapaʻau ʻo Jynarque.

Nā poʻe maʻi CKD pae mua (pae 1 a i ʻole 2)

Ma kēia noiʻi, ua emi nui ka nui o ka hoʻonui ʻia ʻana o nā puʻupaʻa i ka poʻe i lawe iā Jynarque i hoʻohālikelike ʻia me ka poʻe i lawe i ka placebo. I ka pololei, ua emi ka nui o ka hoʻonui ʻia ʻana o nā puʻupaʻa i ka poʻe i lawe iā Jynarque ma kahi o 49% i hoʻohālikelike ʻia me ka poʻe i lawe i ka placebo. ʻO ke ʻano kēia ua kāohi nui ʻia ka hōʻino ʻana i nā puʻupaʻa. Eia kekahi, ua emi pū ka ʻeha o ka poʻe i lawe iā Jynarque.

Nā poʻe maʻi CKD pae hope loa (pae 3 a i ʻole 4)

I loko o kēia hui o nā maʻi, ua lohi iki ka nui o ka hōʻino ʻana o ka hana o nā puʻupaʻa i ka poʻe i lawe iā Jynarque ma mua o nā poʻe ʻē aʻe. ʻO ke ʻano kēia, hiki i kēia lāʻau ke kōkua i ka mālama ʻana i ka hana o ko lākou mau puʻupaʻa no kekahi manawa lōʻihi, ʻoiai i ka poʻe i lilo i mea koʻikoʻi.

Nā hopena ʻaoʻao a pehea e mālama ai iā lākou?

Aia kekahi mau hopena ʻaoʻao i ka wā e hoʻohana ai iā Jynarque, a he mea nui e ʻike iā lākou.

• Ka mimi pinepine ʻana: ʻO kēia ka hopena ʻaoʻao maʻamau. Hiki i kēia ke kumu iā ʻoe e pono ai e hele pinepine i ka lua, i ke ao a me ka pō. No ka hōʻemi ʻana i ka ʻeha i ka pō, e lawe i ka lua o ka mahele i ka manawa like, ʻaʻole ma hope o ke ahiahi.
• Ka maloʻo ʻana o ka wai: Aia kahi pilikia o ka maloʻo ʻana o ka wai no ka mea ua nalowale ke kino i ka nui o ka wai. No ka pale ʻana i kēia, e inu i ka wai nui i ka lā a pau, me ke kali ʻole a hiki i kou make wai ʻana . E inu koke i ka wai ke make wai ʻoe. Hiki i ka maloʻo ʻana ke hoʻonui i nā pae sodium i loko o ke koko. Inā ʻike ʻoe i nā hōʻailona e like me ka poniuniu, ka nāwaliwali , ka luhi nui, ka hāʻule ʻana, a i ʻole ka puʻuwai puʻuwai kūpono ʻole , e hoʻomaopopo koke i kāu kauka.

ʻAʻole wale kēia mau mea, akā hiki ke loaʻa nā hopena ʻaoʻao ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i nā hōʻailona e hoʻopilikia nei iā ʻoe.

Hiki paha ke loaʻa nā pilikia me nā lāʻau lapaʻau a meaʻai ʻē aʻe?

ʻAe, he mea nui loa nō hoʻi kēia.

• Nā lāʻau lapaʻau ʻē aʻe: Hiki iā Jynarque ke launa pū me kekahi mau lāʻau lapaʻau ʻē aʻe. Hiki i kekahi mau lāʻau lapaʻau ke hoʻonui i nā hopena ʻaoʻao o Jynarque, aʻo kekahi e hōʻemi paha i ka pono o Jynarque. No laila, e hōʻoia e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora a me nā lāʻau lapaʻau lāʻau).
• ʻAi: Mai ʻai i ka pomelo a inu paha i ka wai pomelo i ka wā e lawe ana i kēia lāʻau lapaʻau. Hoʻonui ka pomelo i ka pae o Jynarque i loko o ke kino, e hoʻonui ana i ka pilikia o nā hopena ʻaoʻao. Hiki ke hana ʻia kēia hopena ʻoiai inā ʻoe e ʻai i ka pomelo i kekahi manawa ʻē aʻe o ka lā, ʻaʻole i ka wā e lawe ana i ka lāʻau lapaʻau, no laila e pale loa i ka pomelo.

Aia kekahi ala kūikawā e loaʻa ai kēia lāʻau lapaʻau?

He lāʻau lapaʻau ʻo Jynarque nona ka hiki ke hōʻino i ke akepaʻa. Ma muli o kēia pilikia, loaʻa wale kēia lāʻau lapaʻau ma lalo o kahi papahana kūikawā i kapa ʻia ʻo REMS Program . Pono ʻoe e kākau inoa i kēia papahana ma mua o kou hoʻomaka ʻana e lawe i ka lāʻau lapaʻau. Pono nō hoʻi ʻoe e loaʻa nā hoʻāʻo koko e nānā i ka hana o kou akepaʻa. Pono ʻoe e hoʻomau i ka loaʻa ʻana o kēia mau hoʻāʻo koko i nā manawa maʻamau ma hope o kou hoʻomaka ʻana e lawe i ka lāʻau lapaʻau. He mea nui e hoʻomau ʻoe i ka lawe ʻana i kēia mau hoʻāʻo inā makemake ʻoe e hoʻomau i ka lawe ʻana i ka lāʻau lapaʻau. E wehewehe hou aku kāu kauka e pili ana i kēia. ʻO Jynarque, Tolvaptan, ADPKD, Maʻi Kidney Polycystic, Maʻi Kidney, Kidney Cysts, CKD, Kidney Failure, Maʻi Kidney Mau, Jambola