Ua ʻike paha ʻoe he maʻi hoʻonāwaliwali iki ka Ankylosing Spondylitis (AS) no ke ola holoʻokoʻa. Ua ʻike ʻoe i ka paʻakikī o ka hele ʻana i ka lā me ka ʻeha hope a me ka ʻoʻoleʻa o ke kakahiaka. Akā, aia ka nūhou maikaʻi. ʻOiai ʻaʻole hiki ke ho'ōla piha ʻia kēia maʻi, hiki iā mākou ke kāohi i kona mau hōʻailona me ka lāʻau lapaʻau kūpono, ka hoʻoikaika kino, a me ke ʻano ola kino olakino. Hiki i kēia mau lāʻau lapaʻau ke kōkua i ka hoʻōki a hoʻopaneʻe paha i ka holomua o nā pilikia hope.
Ka Papa Hana ʻEkahi: NSAIDs - no ka ʻeha a me ka pehu
Ke hele ʻoe i ke kauka, ʻo kēia ke ʻano lāʻau lapaʻau mua a lākou e hoʻāʻo ai e hāʻawi iā ʻoe no kēia maʻi. Kāhea mākou i kēia mau lāʻau Nonsteroidal Anti-inflammatory, a i ʻole (NSAID) no ka pōkole. ʻOiai hiki ke kūʻai ʻia kekahi o kēia mau mea ma ke kūʻai aku ma ka hale kūʻai lāʻau lapaʻau, pono kekahi i kahi kauoha mai ke kauka.
I ka ʻōlelo maʻalahi, hana kēia mau lāʻau lapaʻau ma ka hoʻōki ʻana i ka hana ʻana o nā kemika i kapa ʻia ʻo prostaglandins i loko o ko mākou kino e hoʻoulu ai i ka mumū. Hoʻemi kēia i kou ʻeha a me ka pehu. ʻO ka lawe ʻana i kēia mau lāʻau lapaʻau i ka pō, ʻoi aku hoʻi, hiki ke kōkua iā ʻoe e hiamoe maikaʻi a hōʻemi i ka ʻoʻoleʻa o ke kua i ke kakahiaka.
ʻO ka mea nui loa, ʻo ia ka lawe ʻana i kēia lāʻau lapaʻau ma ka nui i kuhikuhi ʻia a no ka manawa i kuhikuhi ʻia e like me ke kauoha a kāu kauka . Mai hoʻōki a hoʻololi paha i ka nui i ka makemake.
| ʻAno lāʻau lapaʻau (NSAID) | Nā hopena ʻaoʻao a me nā mea e pono ai ke ʻike |
|---|---|
| Hiki i kēia lāʻau lapaʻau ke hoʻonāukiuki i ka ʻōpū ke hoʻohana ʻia no ka manawa lōʻihi. Eia kekahi laʻana:
No laila, hiki i kāu kauka ke kuhikuhi i nā lāʻau lapaʻau ʻē aʻe (e like me nā antacids) e pale i kou ʻōpū me kēia lāʻau lapaʻau. Inā he moʻolelo kou o ka maʻi puʻuwai, pono ʻoe e haʻi aku i kāu kauka. Hiki i kekahi mau NSAID ke hoʻonui iki i ka pilikia o ka hōʻeha puʻuwai a i ʻole ka hahau ʻana. |
KaʻAnuʻu Hana ʻElua: DMARDs - Nā Lāʻau Lapaʻau Anti-Rheumatic e hoʻololi ana i ka maʻi
I kekahi manawa, ʻaʻole lawa paha nā NSAID wale nō e kāohi i kāu mau hōʻailona. Inā pēlā, hiki i kāu kauka ke kuhikuhi iā ʻoe i kahi ʻano lāʻau i kapa ʻia ʻo (DMARDs) , ʻo ia hoʻi ka Disease-Modifying Antirheumatic Drugs . ʻOiai ke kani paʻakikī paha ka inoa, he maʻalahi kāna hana. Hana ia ma ka hoʻopaʻa ʻana i ka hōʻino ʻia o kou mau hono a me nā ʻiʻo i hoʻokumu ʻia e ka mumū. Hoʻolohi kēia i ka holomua o ka maʻi.
| ʻAno lāʻau lapaʻau (DMARD) | Nā mea e ʻike pono ai |
|---|---|
| ʻO Sulfasalazine | Lawe ʻia kēia ma ke ʻano he pila. Hiki i kekahi poʻe ke loaʻa i ke poʻo ʻeha, ka pehu ʻana, ka luaʻi, a me nā ʻeha waha. He mea kākaʻikahi loa, hiki ke hoʻopilikia ʻia ka iwi iwi, no laila e nānā pinepine kāu kauka i kou koko i ka wā e hāʻawi ai iā ʻoe i kēia lāʻau lapaʻau. |
| ʻO Methotrexate | Hiki mai kēia ma ke ʻano he pila a i ʻole he inikini hiki iā ʻoe ke hāʻawi iā ʻoe iho. Pono ʻoe e lawe i kahi pila folic acid me kēia. ʻO kēia ke pale aku i nā hopena ʻaoʻao e like me nā ʻeha waha a me ka nausea. ʻOiai he lāʻau ikaika kēia, e nānā pinepine kāu kauka i kou koko a me ka hana o ke akepaʻa. ʻAʻole kūpono kēia lāʻau no nā wahine hāpai a i ʻole ka poʻe e hoʻāʻo nei e hāpai. |
ʻO Corticosteroids - hoʻomaha wikiwiki no nā hono ʻeha
He ʻano steroid kēia. Hiki i kāu kauka ke hāʻawi iā ʻoe i kahi inikini steroid, e like me ka "Prednisone", pololei i loko o kou hui ʻeha a pehu. E hāʻawi koke kēia i ka hōʻoluʻolu mai ka ʻeha a me ka pehu.
Akā e hoʻomanaʻo, ʻaʻole kēia he lāʻau lapaʻau i hāʻawi ʻia i ke kino holoʻokoʻa. Eia kekahi, ʻaʻole hiki ke hāʻawi pinepine ʻia kēia mau inikini. ʻO ka maʻamau, hāʻawi ke kauka i kēia mau inikini i kekahi mau manawa wale nō i ka makahiki, me kahi manawa o kekahi mau mahina.
ʻO Biologics - ke ʻano lapaʻau hou loa a ikaika loa
Inā ʻaʻole holo pono nā lāʻau ʻē aʻe iā ʻoe, e haʻi aku paha kāu kauka iā ʻoe e pili ana i kēia lāʻau hou. Ua kapa ʻia kēia mau mea he biologics . Hana ʻia lākou mai nā ʻāpana ola. ʻO ke kikoʻī, ke ālai nei kēia mau lāʻau i nā protein i kapa ʻia ʻo cytokines e hoʻoulu ai i ka mumū i loko o kā mākou ʻōnaehana pale. He lāʻau lapaʻau i kuhikuhi ʻia kēia. Hele mai kēia mau mea ma ke ʻano he injections. Hiki iā ʻoe ke hāʻawi iā ʻoe iho ma ka home.
Nā mea hoʻopaʻa TNF
He ʻano biologic kēia i hoʻohana pinepine ʻia no AS. ʻO TNF ke kū nei no kahi protein i kapa ʻia ʻo "Tumor Necrosis Factor". Hoʻōla kēia mau lāʻau i ka mumū ma ka iwi kuamoʻo, nā hono, nā maka, a me nā ʻōpū. Hiki iā lākou ke hoʻolohi i ka holomua o AS.
- ʻAdalimumab (Humira)
- ʻO Certolizumab pegol (Cimzia)
- ʻEtanercept (Enbrel)
- ʻO Golimumab (Simponi)
- ʻO Infliximab (Remicade)
Nā mea pale o Interleukin (IL-17)
Inā hana ʻole nā mea hoʻopaʻa TNF, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kēia ʻano.
- ʻIxekizumab (Taltz)
- ʻO Secukinumab (Cosentyx)
He mau lāʻau lapaʻau ikaika loa nā biologics. ʻO ia ke kumu he mau hopena ʻaoʻao ko lākou e makaʻala ai. E wehewehe kāu kauka i kēia mau mea āpau iā ʻoe ma mua o kou hoʻomaka ʻana i ka lāʻau.
| Nā pilikia nui a me nā hopena ʻaoʻao o nā biologics | |
|---|---|
| Ka pilikia o ka maʻi | Ma muli o ke kāohi ʻana o kēia mau lāʻau i ka ʻōnaehana pale i kekahi ʻano, hoʻonui lākou i ka pilikia o ka loaʻa ʻana o nā maʻi, ʻoiai ka maʻi puʻupuʻu (TB). No laila, he mea nui e hoʻāʻo ʻia no ka TB ma mua o ka hoʻomaka ʻana i kēia mau lāʻau. |
| Nā pilikia ʻē aʻe | - He piʻi iki loa o ka pilikia o ka maʻi ʻaʻai ʻili. - Hoʻonui ʻia ka pilikia o ka maʻi kanesa lymphoma i nā keiki. - Inā loaʻa iā ʻoe ka maʻi ʻōpū mumū (IBD), e ʻoi aku ka ʻino o kāu mau hōʻailona. |
Inā ʻaʻole ʻoe e ʻoi aku ka maikaʻi ma hope o 3 mau mahina o kēia lāʻau lapaʻau, e hoʻoholo kāu kauka e hoʻōki i ka lāʻau lapaʻau a hoʻololi paha iā ʻoe i kahi biologic ʻē aʻe.
Manaʻolana no nā lāʻau lapaʻau e hiki mai ana
Ke hana nei nā kānaka ʻepekema i kēia manawa e ʻimi i nā lāʻau lapaʻau hou e hiki ke hoʻohuli i ka AS. Ke aʻo pū nei lākou pehea e hoʻopilikia ai ko mākou mau genes i ka maʻi. Hiki i kēia noiʻi ke alakaʻi i nā lāʻau lapaʻau ʻoi aku ka maikaʻi e pili pono ana iā ʻoe i ka wā e hiki mai ana.
Leka Lawe-Home
- He maʻi ia no ke ola holoʻokoʻa o ka Ankylosing Spondylitis (AS), akā hiki ke hoʻomalu maikaʻi ʻia me ka mālama kūpono a me ke ʻano o ka nohona.
- Hoʻomaka pinepine ka lāʻau lapaʻau me nā NSAID. Inā ʻaʻole kēia mau mea e kāohi i ke kūlana, hoʻohana ʻia nā lāʻau lapaʻau e like me DMARDs a i ʻole biologics.
- E hilinaʻi i kāu kauka. E hahai pono i kāna mau kuhikuhi. E hele i nā keʻena lapaʻau i ka manawa kūpono a e hoʻāʻo ʻia.
- Mai ho'ōki i ka lawe ʻana i kāu lāʻau lapaʻau a hoʻololi paha i ka nui o ka lāʻau ma kāu iho. Inā he mau hopohopo kāu, e kamaʻilio me kāu kauka.
- Me ka lāʻau lapaʻau, ka hoʻoikaika kino kūpono a me ka ʻai olakino ʻelua mau mea nui e kaohi ai i kēia maʻi.
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