Koj puas muaj qog nqaij hlav ntawm koj lub qog pituitary? (Pituitary Adenoma) Cia peb kawm txog nws!

Koj puas muaj mob taub hau yam tsis muaj laj thawj? Los yog koj puas xav tias koj lub qhov muag tsis pom kev zoo, thiab koj tsis pom tej yam los ntawm sab nraud zoo? Los yog, koj puas muaj kev tsis xis nyob los ntawm qee qhov kev hloov pauv hauv koj lub cev cov tshuaj hormones? Tej zaum qhov laj thawj tom qab tej yam no yog ib qho qog me me uas loj hlob hauv koj lub qog pituitary. Hnub no, peb yuav tham txog qhov mob no hu ua 'Pituitary Adenoma' . Tsis txhob txhawj, qhov no tsis yog mob qog noj ntshav.

Lub qog pituitary adenoma yog dab tsi?

Hais yooj yim xwb, tus mob pituitary adenoma yog ib qho mob qog uas tsis yog mob qog (benign) uas loj hlob hauv koj lub qog pituitary. Nws tsis kis mus rau lwm qhov ntawm lub cev zoo li mob qog. Qhov ntawd yog qhov tseem ceeb tshaj plaws. Txawm li cas los xij, thaum tus mob adenoma no loj hlob, nws tuaj yeem nias rau ntawm cov hlab ntsha thiab cov hlab ntsha nyob ib puag ncig nws. Qhov ntawd yog thaum cov tsos mob pib tshwm sim.

Yog li, qhov no yog dab tsi pituitary caj pas?

Xav txog, tom qab peb lub qhov ntswg, txuas nrog lub hauv paus ntawm lub hlwb, "Hypothalamus", muaj ib lub qog me me li lub taum pauv. Qhov ntawd yog qhov nws hu ua lub qog pituitary. Txawm hais tias nws me me, nws ua lub luag haujlwm tseem ceeb heev hauv peb lub cev. Lub qog no muaj ob feem tseem ceeb:

• Lub Lobe pem hauv ntej
• Posterior Lobe

Ob qho tib si no tsim thiab tso tawm ntau hom tshuaj hormones rau hauv cov ntshav. Cov tshuaj hormones zoo li cov tshuaj xa xov uas tswj thiab sib koom tes ntau yam haujlwm hauv peb lub cev. Lawv mus ncig los ntawm cov ntshav thiab xa cov lus tsim nyog rau peb cov kabmob, cov leeg, thiab lwm yam nqaij. Nov yog qee cov tshuaj hormones tseem ceeb uas lub qog pituitary tsim tawm:

• Adrenocorticotropic hormone (ACTH los yog Corticotropin)
• Cov tshuaj hormones antidiuretic (ADH lossis Vasopressin)
• Cov tshuaj hormones txhawb nqa follicle ( FSH )
• Cov tshuaj hormones loj hlob ('GH')
• Cov tshuaj hormones Luteinizing (LH)
• Oxytocin ( Oxytocin )
• Prolactin
• Cov tshuaj hormones txhawb cov thyroid (TSH)

Tsis yog qhov no xwb, lub qog pituitary kuj "qhia" lwm cov qog endocrine hauv peb lub cev kom tsim cov tshuaj hormones. Yog li koj tuaj yeem nkag siab tias yog tias muaj teeb meem nrog lub qog pituitary no, xws li adenoma, kev ua haujlwm ntawm ib qho tshuaj hormones lossis ntau yam tshuaj hormones tuaj yeem cuam tshuam.

Yuav ua li cas cais cov hom adenoma no?

Cov kws kho mob faib cov pituitary adenomas ua ob hom tseem ceeb: 1. Raws li seb lawv puas tsim cov tshuaj hormones lossis tsis tsim:

• Kev Ua Haujlwm / Kev Tso Tawm adenoma:Ntxiv mus, cov hom adenomas no tsim ib lossis ntau cov tshuaj hormones pituitary. Yog li ntawd, cov tsos mob thiab cov mob sib txawv tuaj yeem tshwm sim nyob ntawm cov tshuaj hormones uas tsim ntau dhau.
• Cov adenomas tsis ua haujlwm/tsis tso tawm: Cov adenomas no tsis tsim cov tshuaj hormones. Txawm li cas los xij, yog tias lawv loj hlob tuaj, lawv tuaj yeem ua rau muaj cov tsos mob los ntawm kev nias rau thaj chaw ze ntawm lub hlwb lossis cov hlab ntsha . Qhov no yog hom adenoma uas cov kws kho mob feem ntau ntsib.

2. Los ntawm qhov loj me:

• Microadenomas: Cov no yog cov qog me dua 10 millimeters (uas yog, 1 centimeter).
• Macroadenomas: Cov no yog cov qog nqaij hlav loj dua 10 millimeters. Macroadenomas muaj li ob npaug ntawm microadenomas. Lawv kuj muaj feem ntau dua los ua rau muaj ib lossis ntau cov tshuaj hormones pituitary qis (ib qho mob hu ua hypopituitarism).

Qhov no puas suav tias yog qog hauv hlwb?

Lub qog pituitary yog ib qho qauv uas koom nrog lub endocrine system, thiab tsis yog ib feem ntawm lub hlwb. Nws txuas nrog lub hauv paus ntawm lub hlwb. Txawm li cas los xij, cov kws kho mob xav tias pituitary adenomas yog ib hom qog hauv hlwb . Pituitary adenomas tsuas yog suav txog 10% ntawm cov qog hauv hlwb thawj zaug.

Leej twg tau cov no ntau zaus dua? Nws tshwm sim ntau npaum li cas?

Cov qog pituitary adenomas tuaj yeem tshwm sim thaum twg los tau lub hnub nyoog. Txawm li cas los xij, lawv feem ntau tshwm sim rau cov neeg hnub nyoog 30 thiab 40 xyoo . Cov poj niam kuj muaj feem yuav tshwm sim ntau dua li cov txiv neej. Lawv tshwm sim ntau heev uas lawv suav txog 10% txog 15% ntawm tag nrho cov qog uas loj hlob hauv lub taub hau. Raws li kev suav txheeb, kwv yees li 77 ntawm 100,000 tus neeg muaj tus mob no. Txawm li cas los xij, cov kws tshawb fawb ntseeg tias ntau tus neeg ntxiv, tej zaum txog li 20%, yuav tshwm sim ib qho ntawm qee lub sijhawm hauv lawv lub neej. Ntau zaus, tshwj xeeb tshaj yog cov neeg uas muaj microadenomas ('microadenomas'), tsis muaj tsos mob dab tsi, yog li lawv tsis pom.

Cov tsos mob ntawm tus kab mob pituitary adenoma yog dab tsi?

Cov tsos mob ntawm pituitary adenoma yuav txawv ntawm ib tus neeg mus rau ib tus neeg. Nws feem ntau nyob ntawm ntau yam:

• Seb qhov adenoma loj hlob tuaj thiab ua puas rau lub qog pituitary nws tus kheej, lossis nws puas ua rau muaj "kev cuam tshuam loj heev" rau cov qauv ib puag ncig.
• Puas yog ib qho adenoma uas tso tawm cov tshuaj hormones ('ua haujlwm')? Yog tias yog, cov tsos mob yuav nyob ntawm hom tshuaj hormones uas nws tsim tawm.

Cov tsos mob ntawm 'Mass Effect' uas tshwm sim los ntawm 'Macroadenomas' (cov qog nqaij loj)

Cov adenomas loj ('Macroadenomas') ua rau muaj cov tsos mob feem ntau yog vim muaj kev nias rau ntawm cov nqaij ib puag ncig.

Xav txog seb, yog koj muab ib yam khoom loj tso rau hauv ib chav me me, zoo li tsis muaj chaw txaus rau lwm yam khoom thiab nws puv nkaus.

• Teeb meem pom kev:

Kwv yees li 40% txog 60% ntawm cov neeg uas muaj cov pituitary adenoma lojQhov muag tsis pom kev (pom tsis meej, pom ob sab). Qhov no tshwm sim vim tias cov adenoma nias rau ntawm optic chiasm, uas txuas ob lub qhov muag thiab lub hlwb. Qhov no tuaj yeem ua rau pom tsis meej, tshwj xeeb tshaj yog nyob rau sab. Nws zoo li tus nees pom tsis meej ob sab.

• Mob taub hau :

Muaj coob tus neeg uas muaj cov qog pituitary adenomas yws tias lawv mob taub hau ntau zaus. Qhov no tej zaum yog vim cov qog nqaij hlav nias rau ntawm cov nqaij ib puag ncig. Txawm li cas los xij, vim tias feem ntau cov mob taub hau yog los ntawm ntau yam, lawv kuj tuaj yeem yog los ntawm lwm yam.

• Kev tsis txaus ntawm cov tshuaj hormones:

Cov adenomas loj ('Macroadenomas') tuaj yeem ua rau cov nqaij ntawm lub qog pituitary puas tsuaj thiab txo qhov tsim ib lossis ntau cov tshuaj hormones hauv lub qog pituitary. Qhov mob no hu ua 'Hypopituitarism'. Cov tsos mob uas tshwm sim thaum txhua cov tshuaj hormones raug txo kuj sib txawv.

• Thaum cov tshuaj hormones LH thiab FSH txo qis ('Hypogonadism'): Cov theem ntawm ' Oestrogen' hauv cov poj niam thiab ' Testosterone' hauv cov txiv neej txo qis. Qhov no tuaj yeem ua rau muaj cov tsos mob xws li hws ntau dhau, qhov chaw mos qhuav ntawm cov poj niam, ' Erectile Dysfunction' hauv cov txiv neej, cov plaub hau ntawm lub ntsej muag thiab lub cev tsis loj hlob, kev hloov pauv ntawm tus txiv neej, kev ntshaw kev sib deev tsawg dua, thiab qaug zog heev.
• Thaum TSH cov tshuaj hormones txo qis ('Hypothyroidism'): Cov tshuaj hormones uas cov qog thyroid tsim tawm txo qis. Qhov no tuaj yeem ua rau muaj cov tsos mob xws li qaug zog, cem quav, lub plawv dhia qeeb, tawv nqaij qhuav, o ntawm ob txhais ceg, thiab cov reflex tsis zoo.
• Thaum ACTH hormone qis ('Adrenal Insufficiency'): Lub cev tsim cov hormone 'Cortisol' txo qis. Qhov no tuaj yeem ua rau muaj cov tsos mob xws li ntshav siab qis, xeev siab, ntuav, mob plab, thiab tsis xav noj mov.
• GH (Kev Tsis Txaus Hormone Loj Hlob): Cov tsos mob sib txawv nyob ntawm hnub nyoog. Cov neeg laus yuav muaj kev qaug zog thiab poob cov leeg nqaij.

Cov tsos mob ntawm kev ua haujlwm ntawm adenomas

Ntxiv rau kev tso tawm ib lossis ntau cov tshuaj hormones, ib qho adenoma ua haujlwm tuaj yeem ua rau muaj ntau yam tsos mob thiab mob ntsig txog txhua yam tshuaj hormones.

• Prolactinomas (tseem hu ua Lactotroph Adenomas):

Cov adenomas no tsim cov tshuaj hormones prolactin ntau dhau. Qhov mob no hu ua hyperprolactinemia. Tsuas yog li ntawm 4 ntawm 10 tus qog pituitary yog hom no. Qhov no yog hom pituitary adenoma uas feem ntau pom.Thaum cov tshuaj prolactin nce ntxiv, kev ua haujlwm ntawm lub cev yug me nyuam hauv cov poj niam thiab cov txiv neej tuaj yeem raug cuam tshuam.

• Kev tsis muaj menyuam yog ib qho mob uas cov txiv neej thiab cov poj niam muaj teeb meem xeeb tub.
• Muaj cov kua mis tawm ntawm lub mis txawm tias tsis tau xeeb tub los xij ('Galactorrhea').

• Cov tsos mob ntawm Somatotrophic Adenoma:

Cov adenomas no tsim cov tshuaj hormones loj hlob ('Growth Hormone' lossis 'Somatotropin') ntau dhau. Kwv yees li 2 ntawm 10 tus qog pituitary yog hom no. Cov tsos mob tshwm sim los ntawm qhov no sib txawv raws li hnub nyoog.

• Cov Neeg Laus: Muaj ib qho mob uas tsis tshua muaj tab sis loj heev hu ua 'Acromegaly' tshwm sim. Hauv qhov no, cov pob txha thiab cov nqaij ntawm lub cev loj hlob tsis zoo. Raws li lub sijhawm dhau mus, tes, taw, thiab lub taub hau yuav loj dua, thiab cov duab ntawm lub ntsej muag hloov pauv. Nws kuj tseem cuam tshuam rau kev tswj cov ntshav qab zib, thiab cov leeg plawv kuj tuaj yeem loj hlob.
• Cov menyuam yaus thiab cov hluas: Muaj ib qho mob hu ua gigantism tshwm sim. Lawv loj hlob siab txawv txawv vim yog cov tshuaj hormones loj hlob ntau dhau.

• Corticotroph adenoma:

Cov adenomas no tsim ACTH (adrenocorticotropic hormone) ntau dhau. Kwv yees li 1 ntawm 10 tus qog pituitary yog hom no. Cov tshuaj ACTH ua rau cov qog adrenal tsim cov tshuaj steroid ntau dua xws li cortisol. Qhov no ua rau Cushing's Syndrome (cortisol ntau dhau).

• Ntshav siab.
• Cov leeg tsis muaj zog.
• Mob tawv nqaij yooj yim.
• Muaj kab txaij xim av dav (ntau tshaj 1 cm) ("Stretch Marks") tshwm sim rau ntawm lub plab.
• Kab mob pob txha.
• Cov pob txha tawg.
• Mob ntshav qab zib hom 2.

• Cov tsos mob ntawm thyrotrophic adenoma:

Cov adenomas no tsim cov TSH (thyroid stimulating hormone) ntau dhau. Cov no tsis tshua muaj. TSH ua rau lub qog thyroid tsim cov tshuaj hormones thyroid ntau dua. Qhov no ua rau 'Hyperthyroidism' (mob thyroid ua haujlwm ntau dhau), uas ua rau lub cev ua haujlwm sai dua.

• Lub plawv dhia ceev dua.
• Poob phaus yam tsis muaj laj thawj.
• Cov quav xoob ntau zaus.
• Tawm hws.
• Kev tshee hnyo tes.
• Kev ntxhov siab.

Tseem Ceeb: Muaj ntau lwm yam ua rau mob hyperthyroidism. Mob pituitary adenoma yog ib qho ua rau mob tsawg heev.

• Cov tsos mob ntawm cov gonadotrophs:

Cov adenomas no tsim cov gonadotropins ntau dhau (piv txwv li, cov tshuaj hormones LH thiab FSH). Qhov no kuj tsis tshua muaj.

• Qhov no tuaj yeem ua rau cov poj niam muaj kev hloov pauv tsis tu ncua thiab muaj cov mob xws li Ovarian Hyperstimulation Syndrome (OHSS).
• Cov txiv neej yuav muaj cov tsos mob xws li cov noob qes loj hlob, lub suab tob zuj zus, plaub hau poob (tom qab pob ntseg), thiab cov plaub hau ntawm lub ntsej muag loj hlob sai.
• Cov menyuam yaus kuj tseem tuaj yeem muaj kev laus ua ntej lub sijhawm.

Dab tsi yog cov ua rau muaj pituitary adenoma?

Cov kws tshawb fawb tseem tsis tau paub meej tias yog dab tsi ua rau cov adenomas no. Txawm li cas los xij, qee cov adenomas raug xav tias muaj feem cuam tshuam nrog kev hloov pauv tsis tu ncua ('mutations') hauv cov noob caj noob ces ('DNA') hauv peb cov hlwb. Cov kev hloov pauv caj ces no ua rau cov hlwb hauv lub qog pituitary loj hlob sai thiab tsim ua pawg. Cov kev hloov pauv caj ces no qee zaum tuaj yeem tau txais los ntawm niam txiv mus rau cov menyuam (genetic), lossis lawv tuaj yeem loj hlob tsis tu ncua. Tsis tas li ntawd, pituitary adenomas kuj tseem tuaj yeem txuas nrog qee yam mob caj ces tsis tshua muaj . Qee qhov piv txwv yog:

• "Ntau yam Endocrine Neoplasia hom 1 (MEN1)"
• "Ntau yam Endocrine Neoplasia hom 4 (MEN4)"
• 'Carney complex'
• 'X-LAG syndrome'
• "Succinate dehydrogenase-related familial pituitary adenoma"
• Kab mob Neurofibromatosis hom 1
• Kab mob Von Hippel-Lindau

Ib tug neeg uas muaj tus mob caj ces no muaj feem yuav mob qog pituitary adenoma ntau dua. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov neeg uas tsis muaj tus mob caj ces zoo li no kuj tuaj yeem mob qog no tau.

Cov kws kho mob kuaj mob li cas?

Cov txheej txheem ntawm kev kuaj mob pituitary adenoma sib txawv nyob ntawm hom adenoma uas koj muaj thiab seb nws puas ua rau muaj cov tsos mob. Feem ntau, ib tus neeg uas muaj adenoma uas tso cov tshuaj hormones ('Functioning Adenoma') thawj zaug kuaj pom tias muaj kev tsis sib npaug ntawm cov tshuaj hormones (piv txwv li 'Cushing's Syndrome', 'Acromegaly') raws li cov tsos mob. Tsuas yog tom qab ntawd thiaj li pom adenoma thaum tshawb nrhiav qhov ua rau. Qhov no yog vim tias ntau yam mob uas tshwm sim los ntawm cov tshuaj hormones ntau dhau tuaj yeem muaj lwm yam ua rau tsis suav nrog pituitary adenomas. Tib yam tuaj yeem hais txog pituitary hormone deficiency ('Hypopituitarism'). Qee zaum, pituitary adenoma raug pom tias yog 'Kev Tshawb Pom Tsis Tau' thaum lub sijhawm luam theej duab taub hau ('Imaging Test') rau lwm yam mob. Feem ntau cov adenomas uas pom zoo li no feem ntau me me thiab tsis ua haujlwm.

Yuav ua li cas thiaj kuaj tau qhov no?

Yog koj tus kws kho mob xav tias koj muaj ib qho pituitary adenoma, nws yuav saib xyuas koj cov tsos mob, keeb kwm kev kho mob, thiab kuaj lub cev. Tsis tas li ntawd, lawv yuav pom zoo kom koj kuaj ib lossis ntau qhov kev kuaj hauv qab no:

• Kev Kuaj Ntshav: Nyob ntawm koj cov tsos mob, kev kuaj ntshav yuav raug txiav txim kom kuaj xyuas cov qib ntawm ntau yam tshuaj hormones pituitary.
• Kev Ntsuas Duab: Kev ntsuas MRI (Magnetic Resonance Imaging) ntawm lub taub hau lossisIb qho kev ntsuas 'CT (Computed Tomography)' tuaj yeem tsim cov duab meej ntawm cov qauv hauv lub taub hau. Cov kev kuaj no tuaj yeem lees paub seb puas muaj pituitary adenoma thiab nws loj npaum li cas. Kev kuaj 'MRI' yog qhov kev kuaj uas tsim nyog thiab rhiab heev tshaj plaws rau qhov no.
• Kev Kuaj Qhov Muag: Yog tias koj muaj teeb meem pom kev, koj tus kws kho mob yuav hais kom kuaj qhov muag. Qhov kev kuaj no tseem ceeb vim tias cov qog pituitary loj tuaj yeem ua rau muaj teeb meem pom kev los ntawm kev nias cov hlab ntsha optic, uas txuas lub qhov muag mus rau lub hlwb.

Yuav kho tus mob pituitary adenoma li cas?

Muaj peb txoj kev kho mob pituitary adenomas: phais, tshuaj, thiab kev kho mob hluav taws xob. Qee zaum ib lossis ntau txoj kev no yuav siv ua ke. Vim tias txhua tus neeg lub adenoma thiab mob txawv, koj thiab koj pab neeg kho mob tuaj yeem ua haujlwm ua ke los txiav txim siab txoj kev kho mob uas zoo tshaj plaws rau koj.

Kev phais kom tshem tawm cov adenoma

Yog tias koj muaj ib lub adenoma uas ua rau muaj kev tsis sib npaug ntawm cov tshuaj hormones lossis cuam tshuam rau koj qhov muag pom kev, koj tus kws kho mob yuav pom zoo kom phais kom tshem tawm tag nrho lossis ib feem ntawm lub adenoma. Nyob ntawm qhov loj ntawm lub adenoma thiab qhov hnyav ntawm koj cov tsos mob, ntau dua ib qho kev phais yuav tsum tau ua. Cov kws phais feem ntau ua qhov txheej txheem no siv cov txheej txheem phais hu ua 'Transsphenoidal Surgery' . Qhov no suav nrog kev nkag mus rau hauv lub qhov ntswg thiab hla lub sphenoid sinus (qhov chaw khoob tom qab lub qhov ntswg, hauv qab lub hlwb) kom mus txog lub qog pituitary thiab tshem tawm lub adenoma. Kwv yees li 95% ntawm cov qog pituitary raug tshem tawm li no. Nws yog ib qho txheej txheem muaj kev nyab xeeb. Txawm li cas los xij, yog tias lub adenoma loj dhau los tshem tawm los ntawm lub qhov ntswg lossis nyob rau hauv qhov chaw nyuaj, tus kws phais yuav tsum tau ua phais transcranial. Qhov no yog ib qho txheej txheem tsis tshua muaj rau cov pituitary adenomas.

Kev kho mob nrog tshuaj

Qee hom pituitary adenomas, tshwj xeeb tshaj yog prolactinomas , tuaj yeem tswj thiab ua kom me dua nrog tshuaj. Cov neeg uas muaj prolactinomas (cov no yog hom feem ntau) raug kho thawj zaug nrog cov tshuaj dopamine agonist, xws li Cabergoline (Dostinex®) lossis Bromocriptine (Cycloset®), rau ob peb lub hlis.

Qhov xov xwm zoo yog tias kwv yees li ntawm 80% ntawm cov neeg mob, cov tshuaj no ua rau cov prolactinoma me dua thiab rov qab cov tshuaj hormones prolactin mus rau qhov qub.

Yog tias cov tshuaj tsis ua haujlwm lossis yog tias nws yog lwm hom adenoma, koj tus kws kho mob yuav pom zoo kom phais.

Kev Kho Mob Hluav Taws Xob

Kev kho mob siv hluav taws xob siv cov duab xoo hluav taws xob muaj zog heev los rhuav tshem cov hlwb adenoma, ua rau lub qog me dua lossis tiv thaiv nws kom tsis txhob loj hlob. Kev phais mob Stereotactic Radiosurgery rau Pituitary Adenomas(piv txwv li `Gamma Knife`®) Siv txoj kev kho mob hluav taws xob tshwj xeeb thiab raug heev. Hauv qhov no, ntau lub teeb hluav taws xob raug tsom mus rau adenoma los ntawm ntau qhov kev taw qhia, txo qhov kev puas tsuaj rau cov nqaij ntshiv noj qab haus huv ib puag ncig. Txoj kev no yog siv rau cov chaw seem tom qab phais lossis thaum phais tsis tau.

Cov kev mob tshwm sim ntawm kev kho mob yog dab tsi?

Ib yam li kev kho mob twg los xij, kev kho mob rau pituitary adenoma tuaj yeem muaj qee qhov kev mob tshwm sim.

• Tom qab phais thiab/lossis kho mob hluav taws xob, kwv yees li 60% ntawm cov neeg uas muaj cov qog pituitary adenomas yuav muaj 'Hypopituitarism' (tso zis ib lossis ntau cov tshuaj hormones hauv pituitary tsawg dua). Txawm hais tias qhov no yog ib qho mob uas yuav tshwm sim mus ib txhis, cov tshuaj hloov tshuaj hormones tuaj yeem pab tib neeg ua neej nyob li qub.
• Tej yam teeb meem uas yuav tshwm sim los ntawm kev phais:
• Los ntshav.
• Cov kua dej hauv lub hlwb (CSF) xau (cov kua dej tawm ntawm lub qhov ntswg).
• Kab mob meningitis (kev kis kab mob ntawm cov ntaub so ntswg uas npog lub hlwb).
• Kab mob ntshav qab zib insipidus (tso zis ntau dhau thiab nqhis dej ntau dhau vim tsis muaj cov tshuaj antidiuretic hormone).
• Cov kev mob tshwm sim ntawm cov tshuaj dopamine agonist rau prolactinoma suav nrog: mob taub hau, xeev siab, ntuav, kiv taub hau, thiab qee zaum kev coj cwj pwm tsis zoo.
• Tej zaum yuav muaj tej yam tshwm sim ntawm kev kho mob hluav taws xob:
• Tsis muaj zog ntawm cov tshuaj hormones pituitary (tej zaum yuav tshwm sim dhau sijhawm).
• Kev tsis muaj peev xwm yug me nyuam.
• Tsis pom kev thiab puas tsuaj rau cov ntaub so ntswg ntawm lub hlwb (tsis tshua muaj).
• Tej zaum yuav muaj lwm yam qog nqaij hlav tshwm sim rau tib qho chaw ntau xyoo tom qab kev kho mob (tsis tshua muaj).

Puas tiv thaiv tau kom tsis txhob muaj cov adenomas no?

Tu siab kawg li, tsis muaj dab tsi koj ua tau los tiv thaiv cov pituitary adenomas. Feem ntau, lawv tshwm sim yam tsis paub ua ntej. Txawm li cas los xij, lawv yuav cuam tshuam nrog qee qhov mob caj ces tsis tshua muaj uas tau hais ua ntej. Yog tias ib tug neeg hauv tsev neeg ze (kwv tij, muam, lossis niam txiv) muaj mob caj ces zoo li no, koj tuaj yeem tham nrog koj tus kws kho mob txog kev sab laj thiab kev kuaj mob caj ces kom pom tias koj kuj muaj mob no thiab. Yog tias koj muaj, koj tus kws kho mob tuaj yeem saib xyuas koj ze thiab nrhiav thiab kho cov adenomas uas tshwm sim thaum ntxov.

Qhov kev kwv yees ntawm tus mob no yog dab tsi?

Qhov kev cia siab rau tus mob pituitary adenoma, uas yog, koj txoj kev zoo rov qab thiab kev noj qab haus huv yav tom ntej, nyob ntawm qhov loj thiab hom adenoma, thiab kev kho mob uas koj tau txais .

Qhov xov xwm zoo yog tias feem ntau, thaum lub adenoma raug tshem tawm tag nrho lossis tswj tau nrog kev kho mob, cov neeg mob tuaj yeem ua neej nyob zoo thiab noj qab nyob zoo dua.

Qee zaum, kev kho mob tuaj yeem txo qhov kev tsim cov tshuaj hormones los ntawm lub qog pituitary. Yog tias qhov no tshwm sim, koj yuav tsum tau noj cov tshuaj hloov tshuaj hormones rau tas koj lub neej kom hloov cov tshuaj hormones uas txo qis. Qee zaum cov adenomas tuaj yeem rov tshwm sim dua. Qhov no txhais tau tias lawv yuav tsum tau kho dua tom qab ib ntus. Cov ntaub ntawv qhia tau tias kwv yees li 18% ntawm cov neeg uas muaj cov adenomas tsis ua haujlwm thiab kwv yees li 25% ntawm cov neeg uas muaj prolactinoma yuav xav tau kev kho mob dua yav tom ntej. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum sib cuag nrog koj tus kws kho mob tsis tu ncua thiab kuaj xyuas tsis tu ncua.

Puas ua tau nyob nrog pituitary adenoma?

Yog, koj ua tau. Yog tias lub pituitary adenoma me me thiab tsis ua rau muaj tsos mob, koj tuaj yeem nyob nrog nws li qub. Qhov tseeb, ntau tus neeg tsuas pom tias lawv muaj adenoma thaum lawv tau kuaj lub taub hau rau lwm qhov laj thawj. Txawm li cas los xij, yog tias lub adenoma txuas ntxiv loj hlob lossis pib ua rau muaj tsos mob, koj yuav tsum tau kho. Yog tias koj muaj lub pituitary adenoma loj thiab / lossis nquag (tsim cov tshuaj hormones), koj yuav tsum tau kho. Qhov no yog vim qee qhov pituitary adenomas tuaj yeem muaj kev cuam tshuam loj rau koj txoj kev noj qab haus huv thiab lub neej zoo.

Yog tsis kho ces yuav muaj teeb meem dab tsi tshwm sim?

Yog tias tsis kho, qee cov pituitary adenomas - tshwj xeeb tshaj yog cov adenomas loj ('Macroadenomas') thiab cov functional ('Secreting') adenomas - tuaj yeem ua rau muaj teeb meem kev noj qab haus huv loj . Cov teeb meem kev noj qab haus huv no nyob ntawm hom tshuaj hormones uas adenoma tso tawm (peb tau tham txog qhov no ua ntej hauv ntu 'Cov tsos mob'). Ib qho teeb meem tsis tshua muaj tab sis txaus ntshai heev ntawm cov pituitary adenomas uas tsis kho yog 'Pituitary Apoplexy'. Qhov no yog 'Kev Kho Mob Xwm Ceev'. Qhov no tshwm sim thaum muaj ntshav nkag mus rau hauv lossis tawm ntawm lub qog pituitary. 'Pituitary Apoplexy' feem ntau yog los ntawm kev ntshav mus rau hauv pituitary adenoma. Lub qog sai sai loj hlob, ua rau lub qog pituitary puas tsuaj. Lub adenoma loj dua, qhov muaj feem ntau ntawm kev mob 'Pituitary Apoplexy'. Cov tsos mob ntawm 'Pituitary Apoplexy' feem ntau tshwm sim sai heev thiab tuaj yeem ua rau tuag taus . Cov tsos mob tseem ceeb yog:

• Mob taub hau hnyav heev (zoo li mob taub hau phem tshaj plaws uas kuv tau muaj hauv kuv lub neej).
• Pom ob sab lossis tsis muaj peev xwm tsa lub qhov muag vim yog kev ua haujlwm tsis zoo ntawm cov leeg nqaij ntawm lub qhov muag.
• Tsis pom kev ntawm ib sab lossis ob lub qhov muag kiag li.
• Kev tsis muaj zog ntawm adrenal ua rau muaj ntshav siab qis, xeev siab, thiab ntuav.
• Kev hloov pauv ntawm tus cwj pwm (piv txwv li, kev tsis meej pem) vim yog qhov nqaim ntawm cov hlab ntsha hauv lub hlwb pem hauv ntej.

Mob qog hauv lub qog pituitary apoplexy yog ib yam mob uas tsis tshua muaj, tab sis nws yog ib yam mob hnyav heev. Yog tias koj muaj ib lossis ntau yam ntawm cov tsos mob no, hu rau cov kev pabcuam kho mob thaum muaj xwm txheej ceev (xws li 911) tam sim ntawd lossis kom ib tus neeg coj koj mus rau chav kho mob thaum muaj xwm txheej ceev hauv tsev kho mob ze tshaj plaws.

Thaum twg koj yuav tsum mus ntsib kws kho mob?

• Yog tias koj muaj teeb meem pom kev (pom tsis meej, pom ob sab, pom tsis meej) thiab/lossis mob taub hau tas li lossis rov tshwm sim (tshwj xeeb tshaj yog nyob rau hauv thaj tsam hauv pliaj), mus ntsib kws kho mob thiab qhia rau lawv paub.
• Yog tias koj twb tau kuaj pom tias muaj pituitary adenoma lawm, koj yuav tsum mus ntsib koj tus kws kho mob tsis tu ncua kom saib xyuas qhov mob ntawm adenoma thiab kom paub tseeb tias kev kho mob ua haujlwm zoo.

Thaum kawg, nco ntsoov cov no:

Nws yog ib qho ib txwm muaj uas yuav ntshai thiab txhawj xeeb thaum koj pom tias koj muaj qog nqaij hlav. Txawm li cas los xij, cov xov xwm zoo txog pituitary adenomas yog tias lawv feem ntau (ntau dua 99%) tsis yog mob qog nqaij hlav (benign) thiab feem ntau, kev kho mob tuaj yeem ua rau muaj txiaj ntsig zoo heev. Nco ntsoov, koj tus kws kho mob yog koj tus khub hauv kev ua kom koj muaj kev noj qab haus huv zoo tshaj plaws. Yog li ntawd, tsis txhob yig qhia rau koj tus kws kho mob txog txhua yam tsos mob, kev tsis xis nyob, lossis cov lus nug uas koj muaj txog koj txoj kev kho mob. Nrog cov ntaub ntawv raug thiab kev kho mob raws sijhawm, koj tuaj yeem tswj hwm qhov mob no tau zoo.