Yu dɔn ɛva notis se sɔmbɔdi na yu famili, sɔntɛm yu grani, granpa, ɔ wan pan yu mama ɛn papa we yu lɛk, de fɔgɛt ɔltin smɔl smɔl? Yu tink se i nɔ kin izi fɔ yu fɔ du tin dɛn we yu bin de du fayn fayn wan, lɛk fɔ mek gadin, fɔ du wok na os, ɔ fɔ fɛn we fɔ go? Dis na di pikchɔ wae bɔrku pan wi kin tink bɔt wae wi yɛri di wɔd Alzheimer’s Disease. Bɔt yu no se difrɛn kayn dis sik de? I nɔ de afɛkt ɔlman di sem we. Tide, wi go tɔk bɔt am.
Wetin na di sik we dɛn kɔl Alzaima?
Bifo wi tɔk bɔt dɛn kayn tin ya, lɛ wi ɔndastand rili simpul wan wetin kin apin to di bren pan Alzaima sik. Imajin se wi bren na wan wɔndaful nɛtwɔk we gɛt bɔku bɔku nyuron dɛn ɔ nerv sɛl dɛn we de wok togɛda. Ɔl wetin wi de tink, mɛmba, ɛn lan na di kɔmyunikeshɔn bitwin dɛn sɛl dɛn ya.
Insay di sik we dɛn kɔl Alzaima, wan kayn prɔtin we dɛn kɔl amyloid beta peptides kin bigin fɔ gɛda na di bren di we aw i nɔ want. Dɛn tin ya kin gɛda fɔ mek plek ɛn tandul . Fɔ tɔk am simpul wan, i tan lɛk se di kɔmyunikeshɔn sistɛm na di bren dɔn blok. Dis kin ambɔg di kɔmyunikeshɔn bitwin di nɛv sɛl dɛn, ɛn as tɛm de go, dɛn sɛl dɛn de kin day. Dis kin mek yu gɛt sayn dɛm lɛk wae yu nɔr de mɛmba fayn, yu kin kɔnfyus, ɛn i nɔ kin izi fɔ disayd fɔ du sɔntin.
De impɔtant tin na dat, pan ɔl we dɛn sik ya kin kam as tɛm de go pan ɛvri pɔsin we gɛt Alzaima, aw di sik kin bigin ɛn aw i kin spid kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Dis na bikɔs ɔf di difrɛn kayn sik wae wi de tɔk bɔt.
De tu men kayn sik wae de kam wit Alzaima
Sayɛnsman dɛn kin sheb di sik we dɛn kɔl Alzaima to tu men grup, bay di ej we dɛn dɔn no bɔt dis sik. Lɛ wi tek tɛm luk di difrɛns bitwin dɛn tu.
| Di kwaliti we pɔsin gɛt | Alzaima we kin bigin kwik kwik wan | Alzaima we kin bigin let |
|---|---|---|
| Di ej fɔ bigin | Ɔnda 65 ia (bɔku tɛm na dɛn 40-50 ia) . | 65 ia ɔ pas dat |
| Bɔku | Rare (lɛk 5% pan ɔl di pasɛnt dɛn) . | Di kayn we we kɔmɔn pas ɔl |
| Rilayshɔnship bitwin jɛnɛtiks | Bɔku tɛm, wan strɔng jɛnɛtik link de (difɛkt dɛn na di kromozom 1, 14, ɛn 21) . | Di jɛnɛtik link nɔ klia. I kin rɔn na famili ɔ i nɔ kin rɔn. |
| Bren kin chenj | dεn de si mכr plek dεm εn tangle dεm na di bren εn di bren vכlyum we de lכs. | Pan ɔl we di chenj dɛn we de apin na di bren kin apin, i kin de na smɔl smɔl tin we yu kɔmpia am to ɔda kayn tin dɛn. |
| Ɔda sayn dɛn we de sho se yu gɛt dis sik | di mכsul dεm we de twitch εn jכk (myoclonus) na kכmכn tin. | Bɔku tɛm, dis kwaliti nɔ kin apin so ɔltɛm. |
| Speshal risk dɛn we kin apin | Pipul wae gɛt Down syndrome kin gɛt bɔrku risk. | We pɔsin ol na di men tin we kin mek i gɛt prɔblɛm. |
Smɔl mɔ bɔt Alzaima sik we kin bigin kwik kwik wan
Imajin, wetin go apin if pɔsin we de na di tɔp pan dɛn wok, we de mɛn in pikin dɛn, ɛn we de spɛn bɔku tɛm na in layf, bigin fɔ gɛt prɔblɛm wit mɛmori we i ol lɛk 45 ia so? Dis na de pat wae de sɔri pasmak pan Alzaima sik wae kin bigin kwik kwik wan. Pan ɔl we i nɔ kin apin so ɔltɛm, i kin mek di pɔsin ɛn in famili we dɛn kin no se gɛt dis sik kin rili sɔprayz.
Di damej pan di bren na dɛn sik pipul ya kin bi kwik kwik wan ɛn i kin bɔku. כlso, di kכndyushכn kin bi fכ strכng jεnεtik fכktכ dεm - dat na, sכm difεkt na di jin dεm we dεn kin gεt frכm mama εn papa to pikin dεm.
Let-onset Alzheimer's - de kayn wae wi ɔl no
Dis na de kayn wae wi kin si ɛn tɔk bɔt bɔrku tɛm wae wi kin tɔk bɔt Alzaima. Wi dɔn si se wi grani ɛn granpa dɛn nɔ de mɛmba bɛtɛ smɔl smɔl as dɛn de ol. Dis na am. Dɛn nɔ dɔn fɛn di rayt jenɛtik kɔz fɔ dis kayn tin yet. Dat min se dɛn nɔ go se yu go mɔs gɛt am if yu mama ɔ papa bin gɛt di sik. Bɔt if pɔsin na yu famili gɛt am, ɔda pipul dɛnsɛf de pan sɔm risk. Bɔt dɛn biliv se bɔku tin dɛn lɛk di jin, di we aw pɔsin de liv in layf, ɛn di tin dɛn we de apin na di say we wi de, kin afɛkt dis.
Wetin na Famili Alzaima Disease (FAD)?
Dis na ɔda spɛshal, bɔt rili, rili rare sɔbtayp fɔ Alzaima sik. FAD (Familial Alzheimer’s Disease) na wan kayn Alzheimer’s disease wae dɛn dɔn kɔnfirm se na sɔm patikyula jin dɛm kin kam wit am .
Fɔ tɔk am simpul wan, i nid fɔ gɛt at le tu jɛnɛreshɔn (e.g., wan granpa ɛn wan papa) fɔ gɛt dis sik. Dis kin afɛkt less dan 1% pan ɔl di wan dɛm wae gɛt Alzaima. Impɔtant, bɔrku pipul dɛm wae gɛt Alzaima wae kin bigin kwik kwik wan kin rili gɛt dis kayn FAD. Dat min se, i de pas tru dɛn jin dɛn.
Wetin a fɔ du if a gɛt dawt bɔt pɔsin na mi famili?
If yu gɛt ɛni dawt ɔ fred bɔt di mɛmori fɔ pɔsin na yu famili, mɔ di yɔŋ wan, nɔ ignore am.
- Di bɛst tin fɔ du wantɛm wantɛm na fɔ go to dɔktɔ we gɛt ɛkspiriɛns. I bɛtɛ mɔ if yu kin go to dɔktɔ we de mɛn yu nyuro.
- Di dɔktɔ kin aks bɔt di sayn dɛm ɛn di famili mɛdikal istri.
- Dɛn go du bɔku tɛst fɔ si if ɔda tin dɛn de we kin mek pɔsin nɔ ebul fɔ mɛmba (lɛk we pɔsin nɔ gɛt bɛtɛ vaytamɛn, we i gɛt prɔblɛm wit in tayroyd, ɔ we i kin strɛs).
- If nid de, dɛn go rifer yu fɔ tin dɛn lɛk bren skan (CT/MRI).
Mɛmba se, if yu no di sik kwik kwik wan, dat kin ɛp di pɔsin ɛn in famili fɔ plan bifo tɛm ɛn gɛt di sɔpɔt ɛn tritmɛnt we dɛn nid. So nɔ fred fɔ go to dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Alzaima sik nɔto wan sik. Tu men kayn dɛn de: we kin bigin kwik, we kin afɛkt pipul dɛn we nɔ rich 65 ia yet, ɛn we kin kam let, we kin afɛkt pipul dɛn we dɔn pas 65 ia.
- De kayn wae kin bigin kwik kwik wan nɔr kin bɔrku, bɔt in sayn dɛm ɛn in bren kin pwɛl pasmak. Bɔku tɛm, i kin gɛt fɔ du wit wan tin we nɔ fayn na in jɛnɛtiks we kin pas fɔ lɔng lɔng tɛm.
- Di kayn we aw pɔsin kin bigin let we wi kin si bɔku tɛm kin gɛt fɔ du wit ol pipul dɛn. Dɛn nɔ dɔn fɛn ɛni patikyula jɛnɛtik kɔz yet.
- If ɛnibɔdi na yu famili, mɔ we i yɔŋ, de sho sayn dɛn we de sho se i nɔ ebul fɔ mɛmba tin, nɔ ignore am ɛn tɔk to dɔktɔ wantɛm wantɛm.
- Fɔ no bɔt dis sik ɛn fɔ no am kwik na di bɛst we fɔ ɛp di pɔsin fɔ liv kwaliti layf.
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