Wi ɔndastand di frayd, shɔk, ɛn bɔku kwɛstyɔn dɛn we kin kam we yu kam fɔ no se yu gɛt bɔdi kansa. Bɔt di tin we impɔtant pas ɔl dis tɛm na fɔ mek dɛn no di rayt tin. Bikɔs, nɔto ɔl di bɔdi kansa na di sem. Tritmɛnt dɛn de we dɛn kin tɔk bɔt fɔ sɔm kayn kansa. Wɛl, wan tritmɛnt we dɛn dɔn yuz fayn fayn wan fɔ bɔku pipul dɛn na ɔmon tɛrapi . Lɛ wi tɔk bɔt am jɔs tide.
Wetin na ɔmon tɛrapi? Yu tink se i rayt fɔ ɔlman?
Fɔ tɔk am simpul wan, sɔm ɔmon dɛn we de na wi bɔdi kin ɛp sɔm bɔdi kansa sɛl dɛn fɔ gro. Spɛshal wan, tu ɔmon dɛn we dɛn kɔl ɛstrojen ɛn prɔjɛstɛron.
Tink bɔt kansa sɛl dɛn lɛk smɔl os dɛn. sכm kεnsar sεl dεm gεt spεshal ‘do dεm’ (rεsεptor) we de alaw dεn כmon dεm ya fכ go insay. Wi kin kɔl kansa dɛn we gɛt dɛn domɔt ya ɔmon riseptɔ-pɔzitiv . Dɔktɔ dɛm, yu kin dɔn notis dis na yu ripɔt as ER-positiv (estrogen-doors) ɔ PR-positive (progesterone-doors).
Ɔmon tɛrapi de wok fɔ kansa dɛn we gɛt dɛn ɔmon get ya. Dɛn tritmɛnt ya kin lɔk dɛn get dɛn de ɔ dɛn kin mek dɛn ɔmon dɛn de na di bɔdi nɔ bɔku. dis de mek di kεnsar sεl dεm nכ gεt di "nutrishכn" we dεn nid, we de mek dεn stכp fכ gro כ day.
Di impɔtant tin na dat, if yu kansa sɛl dɛn nɔ gɛt dɛn ɔmon riseptɔ ya, dat min se if dɛn na ɔmon riseptɔ-nɛgitiv , dɛn ɔmon tritmɛnt ya nɔ go wok. Dɔktɔ dɛn kin se ɔda tritmɛnt dɛn fɔ dɛn kayn pipul ya.
Wetin na di men kayn ɔmon tritmɛnt?
Bɔku men kayn ɔmon tritmɛnt dɛn de we dɛn kin yuz fɔ mɛn bɔdi kansa. Yu dɔktɔ go pik di mɛrɛsin we go fayn fɔ yu bay bɔku tin dɛn, lɛk yu ej, di kayn kansa we yu gɛt, ɛn if yu dɔn go tru menopause. Lɛ wi luk tu men kayn dɛn.
| Di kayn tritmɛnt we dɛn kin gi | Udat dɛn kin gi am mɔ to? | Sayd ɛfɛkt dɛn fɔ no |
|---|---|---|
| Tamoksifen we gɛt di sik | Fɔ uman dɛn we gɛt ɛni ej (pri ɛn post menopause). Wan mɛrɛsin we dɛn dɔn de yuz fayn fayn wan fɔ lɔng lɔng tɛm. | Di risk we de go ɔp smɔl fɔ gɛt kansa na di uterin, blɔd we de klɔt na di leg ɛn lɔng, strok, katarakt, ɛn hot flash. |
| Aromatase Inhibitɔ dɛn (AI) dɛn . Eks: Anastrozol, Lɛtrozɔl | Men wan fɔ uman dɛn afta dɛn dɔn menopause. | Bɔn dɛn we wik (Osteoporosis) ɛn risk fɔ brok, jɔyn ɛn mɔsul dɛn pen, mɛmori prɔblɛm, ɛn risk fɔ gɛt at sik smɔl. |
Smɔl mɔ bɔt Tamoxifen
Dis na pil we yu de tek ɛvride. Risach dɔn sho se if pɔsin tek am fɔ sɔm ia, bɔku tɛm na lɛk 5 ia, i kin rili ridyus di risk fɔ mek kansa kam bak ɛn di risk fɔ gɛt nyu kansa.
Bɔt yu fɔ no bak bɔt di bad tin dɛn we kin apin to yu we wi bin tɔk bɔt na da tebul de. Ɛspɛshali di risk fɔ gɛt kansa na di uterin. Na dat mek i fɔ mek yu du ɛgzam na yu bɛlɛ ɔltɛm we yu de tek dis mɛrɛsin. Dɔn bak, if yu gɛt ɛni blɔd we nɔ kɔmɔn na yu vagina, yu fɔ tɛl yu dɔktɔ wantɛm wantɛm.
Smɔl mɔ bɔt Aromatase Inhibitors (AIs)
dis kayn mεdikeshכn de wok bay we i de stכp di כmon we dεn kכl εstrojen fכ mek uman dεm afta dεn dכn mεnopos. Dis kin mek di kansa sɛl dɛn nɔ gɛt di ɔmon we dɛn nid fɔ gro.
Di men risk fɔ dis mɛrɛsin na ɔstioporosis , we na di risk fɔ mek di bon dɛn wik ɛn brok izi wan. Fɔ dis rizin, yu dɔktɔ go mɔs du wan bon dɛnsiti tɛst bifo yu bigin fɔ tek dis mɛrɛsin ɛn we yu de tek am. I kin tɛl yu bak fɔ tek tin dɛn we gɛt kalsiɔm ɛn vaytamɛn D.
Ɔda ɛn advans tritmɛnt dɛn
Apat frɔm di men kayn mɛrɛsin dɛn we wi dɔn tɔk bɔt, ɔda kayn mɛrɛsin dɛn de we dɛn kin yuz, mɔ we di kansa dɔn skata to ɔda pat dɛn na di bɔdi (advans ɔ metastatic).
Fɔ ɛgzampul, drɔgs de lɛk `Fulvestrant (Faslodex)` ɛn `Toremifene (Fareston)`. Apat frɔm dat, bɔku advans mɛrɛsin dɛn de we dɛn kɔl `Targeted Therapy` tide. `Palbociclib (Ibrance)`, `Abemaciclib (Verzenio)`, `Alpelisib (Piqray)` na ɛgzampul fɔ dɛn kayn drɔgs ya. Dɛn tin ya de wok bay we dɛn de tɔch sɔm patikyula prɔtin dɛn we de ɛp di kansa sɛl dɛn fɔ gro. Bɔku tɛm dɛn kin gi dɛn tin ya to di wan dɛn we sik wit di ɔmon tritmɛnt we wi bin dɔn tɔk bɔt.
Dɛn kin disayd fɔ du ɔl dɛn tritmɛnt ya bay aw yu sik, di kayn kansa we yu gɛt, yu ej, ɛn ɔl yu wɛlbɔdi. So nɔ fred fɔ tɔk to yu dɔktɔ bɔt ɛni kwɛstyɔn we yu gɛt .
Speshal tritmɛnt fɔ di wan dɛn we nɔ dɔn go tru menopause (Ovarian Ablation) .
If yu nɔ dɔn pas yet, we min se yu de gɛt prɛgnɛshɔn ɔltɛm , na yu ovaria dɛn de mek di men ɔmon we de na yu bɔdi we gɛt ɛstrojen. So, fɔ pɔsin we gɛt ER-positiv kansa, yu dɔktɔ kin disayd fɔ stɔp dɛn ovaria ya fɔ mek dɛn nɔ mek ɛstrojen. Dɛn kɔl dis ovarian ablation/suppression .
Bɔku we dɛn de fɔ du dis:
- ɔspitul fɔ pul di ovaries : Dis na we fɔ ɔltɛm.
- rεdyushכn tεrapi to di ovaria dεm: Dis kin stכp di ovaria dεm fכ wok fכ כltεm bak.
- mεdikeshכn fכ stכp di ovaria fכ wok fכ sכm tεm: dεn de yuz mεdikeshכn dεm we dεn kכl `(LHRH) agonists` (bכku tεm injεkshכn) fכ dis. As lɔng as yu de tek dɛn mɛrɛsin ya, yu ovaria nɔ go mek ɔmon.
Risach dɔn sho se apat frɔm we dɛn de stɔp dɛn ovaria ya, ɔmon tɛrapi lɛk tamoxifen kin gɛt rili gud rizɔlt.
Mɛsej we dɛn kin kɛr go na os
- Ɔmon tɛrapi nɔto tritmɛnt fɔ ɔl di bɔdi kansa. כnli dεn de gi am to כmon rεsεptכr-positiv (ER/PR-positiv) kεnsar dεm.
- Di tritmɛnt we go fayn fɔ yu (e.g. Tamoxifen ɔ Aromatase Inhibitor) na yu dɔktɔ go disayd, bay yu ej ɛn wɛlbɔdi kɔndishɔn.
- Ɔl dɛn mɛrɛsin ya kin gɛt sayd ɛfɛkt. Nɔ fred dɛn, jɔs no wetin dɛn bi. If yu gɛt ɛni sayn we nɔ kɔmɔn, tɛl yu dɔktɔ wantɛm wantɛm.
- I rili impɔtant fɔ mek yu du di tɛst dɛn we di dɔktɔ tɛl yu fɔ du di rayt tɛm we yu de trit yu.
- Mek shɔ se yu tɔk opin wan bɔt wetin yu de fred, dawt, ɛn kwɛstyɔn dɛn wit yu mɛdikal tim. I go bi big trɛnk fɔ yu fɔ wɛl.
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