Prɔblɛm de wit di difens dɛm na yu nervɔs sistɛm? Lɛ wi lan bɔt Demyelinating Disease!

Wi nervɔs sistɛm tan lɛk wan kɔmpleks sistɛm we gɛt waya. Na tru dɛn waya ya mɛsej dɛn kin kɔmɔt na wi bren to ɔl di pat dɛn na di bɔdi. so dεn ‘ways’ dεm, dat na di nεv sεl dεm `(Nyuron), gεt sכm ‘sheath’ fכ protεkshכn. Wi de kɔl dis `(Myelin) . Dis tan lɛk di plastic sheath we de ɔp wan ilɛktrik waya. dis `(Myelin)` sheath na in de protεkt di nεv sεl dεm εn alaw di ilektrikal mεsej dεm fכ travul tru am kwik kwik wan. Imajin, if sɔntin dɔn pwɛl na dis `(Myelin)` sheath, di mɛsej dɛn we de pas na wi nerv dɛn kin disrɔb, jɔs lɛk waya we gɛt brok brok plastic sheath. Na dat wi kin kɔl `(Demyelinating Disease)` .

Wetin na Demyelinating Disease?

Fɔ tɔk am simpul wan, sik we de mek yu nɔ gɛt di maylin na wan sik we de pwɛl di maylin we de na yu bren, yu spɛnal kɔd, ɛn yu nerv dɛn . as a bin se, maylin na di protεktiv sεt we de rawnd di nyuron dεm na wi sεntri nεv sεstem εn pεrifεral nεv sεstem. dis maylin sεl de mek di nεv sεl dεm strכng, protεkt, εn insכlet. Nɔto dat nɔmɔ, bɔt i de ɛp bak fɔ mek di ilɛktrik impuls dɛn travul bitwin di sɛl dɛn.

So, if yu gɛt wan sik we de mek yu nɔ gɛt di maylin, na dis kin apin: yu imyun sistɛm kin mistek atak dis maylin sheath, ɔ di sɛl dɛn we de mek maylin. Tink bɔt am lɛk wi imyun sistɛm, we tan lɛk wi bɔdi in difens sistɛm, we de atak in yon pipul dɛn. Dis kin chenj di we aw di nerv dɛn de tɔk to dɛnsɛf, di we aw dɛn de wok, ɛn difrɛn sayn dɛn kin bigin fɔ sho.

Wetin na di kayn sik dɛm wae de mek pɔrsin nɔr de fil fayn?

Dɛn sik ya we de mek pɔsin nɔ ebul fɔ du mami ɛn dadi biznɛs di we aw Gɔd nɔ want kin kam insay difrɛn we dɛn. dεn kin kכl dεm we de afekt wi sεntri nεv sεstem mεntal wan (dat na di bren εn di spεnal kכd) εn di wan dεm we de afekt di pεrifεral nεv sεstem (dat na di כda nεv dεm we de kכmכt na di bren εn spεnal kכd).

di kכmכn dεmyelinating sik dεm we de afekt di sεntri nεv sεstem:

• Multiple Sclerosis (MS) : Dis na de sik wae kin pasmak ɛn pipul kin no bɔt dis sik.
• Nyuromaylaytis Ɔptika Spɛktrum Disɔda (NMOSD) .
• Transvεs Mayεlaytis (TM) .
• Akyu Disɛminɛt Ɛnsɛfalomaylaytis (ADEM) .
• Progresiv Maltifokal Lukoɛnsɛfalɔpati (PML) .
• Sεntrial Pכntin Mayεlinכlaysis (dεn kin kכl am bak Osmotik Dεmyεlinεshכn Sεndrכm) .

di kכmכn dεmεylinεt sik dεm we de afekt di pεrifεral nεv sεstem:

• Di sik we dɛn kɔl Guillain-Barré Syndrome (GBS) .
• Charcot-Marie-Tooth Disease (CMT) we de mek pɔsin gɛt tut .
• Kronik Inflammatory Demyelinating Polinyuropati (CIDP) we gɛt fɔ du wit di sik.

"We yu se `Demyelinating Disease`, i min ɔltɛm `(MS)`?"

Nɔ, nɔto so i bi. Bɔku ɔda kɔndishɔn dɛn de we de insay di kategori fɔ Demyelinating Diseases. Bɔt na kɔntri dɛn lɛk Nɔt Amɛrika, MS na di wan we bɔku pan dɛn tin ya.

Aw dɛn sik ya kin bɔku?

Multiple Sclerosis na wan pan di sik dɛm wae kin kam wit demyelinating. Wan stɔdi we dɛn bin du insay 2019 sho se na lɛk wan milyɔn pipul dɛn nɔmɔ na Amɛrika de liv wit MS. Pipul dɛn de we gɛt dis sik na Sri Lanka bak, bɔt i nɔ kin izi fɔ fɛn kɔrɛkt statystik bɔt am.

Wetin na di sayn dɛm fɔ wan sik wae de mek pɔrsin nɔr de fil fayn?

De sayn dɛm fɔ dɛn sik ya kin difrɛn bad bad wan, ɛn dɛn kin difrɛn bak fɔ di kayn sik. Na sɔm kɔmɔn sayn dɛm fɔ wan demyelinating sik we de afɛkt di sɛntral nervous system:

• di chenj we yu de si: yu nɔ de si fayn, yu nɔ ebul fɔ no difrɛns bitwin di kɔlɔ dɛn (espɛshali rɛd ɛn grɛn), pen we yu de muv yu yay, ɔ yu de si tu tin wan tɛm (dɛn si tu tɛm).
• Fɔ fil se yu nɔ gɛt bɛtɛ trɛnk ɔ yu nɔ de fil fayn na difrɛn pat dɛn na yu bɔdi. I tan lɛk se pɔsin dɔn numb yu an ɔ yu leg.
• Di sik we dɛn kɔl ‘MS hug’: I min se yu de fil lɛk se pɔsin de ol yu tayt tayt wan, ɔ rawnd yu chɛst ɔ rawnd yu bɛlɛ.
• Taya: Fɔ fil taya fɔ natin, jɔs plain taya.
• Prɔblɛm fɔ pis ɛn bɔdi: I nɔ kin izi fɔ pis, ɔ yu kin want fɔ pis wantɛm wantɛm (we min se yu fɔ go kwik we yu nid fɔ go), yu kin gɛt bɛlɛ, ɛn ɔda tin dɛn.
• We yu bɛn yu nɛk fɔ go bifo, yu kin fil lɛk se kɔrɛnt de rɔn dɔŋ yu bak, yu an, ɛn yu leg.
• I nɔ izi fɔ waka. Leg dɛn kin tan, i kin tan lɛk se balans dɔn lɔs.
• Di mɔsul dɛn wik ɔ stiff.

Yu kin gɛt jɔs wan pan dɛn sik ya, ɔ yu kin gɛt sɔm pan dɛn di sem tɛm. Dɔn bak, aw dɛn sik ya kin tranga kin chenj as tɛm de go.Dat min se, sɔmtɛm, de sik kin wɔs smɔl (i kin fil mɔr), ɛn afta dat i kin stɔp fɔ sɔm tɛm.

Wetin na de tin wae kin mek pɔrsin gɛt Demyelinating Disease?

di men tin we de mek dεn sik ya na di damej pan di maylin εn di sεl dεm we de mek maylin. As a bin se bifo, dis damej de apin bikɔs wi yon imyun sistɛm de mistek atak wɛlbɔdi maylin. Nɔmal wan, wi imyun sistɛm de protɛkt di bɔdi frɔm tin dɛn we de mek pɔsin sik lɛk baktri ɛn vayrɔs. Bɔt sɔntɛnde, if wi nɔ gɛt di rayt instrɔkshɔn, dis imyun sistɛm kin mistek si wi yon maylin sɛl dɛn as bad tin to di bɔdi. We dat apin, inflamɛns kin apin na dɛn say dɛn de, ɛn dis kin mek pɔsin gɛt di sik we de mek pɔsin nɔ ebul fɔ waka.

Bɔku ɔda tin dɛn kin ɛp fɔ mek di sik we dɛn kɔl demyelinating disease:

• Bikɔs ɔf wan vayral ɔ baktriyal infɛkshɔn .
• jεnεtik prεdispכzishכn (dat na sכm chenj dεm na yu DNA we de inkrεs yu risk fכ divεlכp כtoimyun dizכrd).
• Bikɔs ɔf ɔda sik dɛn we pɔsin kin gɛt, lɛk we i nɔ gɛt bɛtɛ vaytamɛn .

Sɔntɛnde, dɛn nɔ kin ebul fɔ fɛn wan patikyula tin we kin mek pɔsin gɛt dɛn sik ya . Dɛn de du mɔ risach bɔt dis.

Aw dɛn kin no bɔt Demyelinating Disease?

If yu gɛt dɛn sik ya, yu fɔ go to dɔktɔ fɔs. I go lisin to yu sayn dɛm ɛn du ɛgzam fɔ yu bɔdi. I go tek wan kɔmplit mɛdikal istri bak. If i tink se yu gɛt wan sik we de mek yu nɔ gɛt bɛtɛ trɛnk, dɛn kin sɛn yu to dɔktɔ we de mɛn yu nyuro . Nyurolɔjis na dɔktɔ we gɛt spɛshal trenin fɔ sik dɛn we de na di nervɔs sistɛm.

Di nyurolɔjis go du nyurolɔjik ɛgzam ɛn if nid de, i go ɔda ɔda tɛst dɛn. Nɔ wan tɛst nɔ de fɔ no if pɔsin gɛt dimyelination. Yu dɔktɔ go yuz wan ɔ mɔ pan dɛn tɛst ya fɔ pul ɔda sik dɛn we gɛt di sem kayn sik ɛn fɔ no di kɔrɛkt tin:

• MRI (Magnetic Resonance Imaging) scan: Dis kin mek di bren ɛn di spaynal kɔd fayn fayn wan.
• di lכmba pankshכn כ di spεnal tap: dis min fכ tek sכm sכm sכm sεribrospεnal fכluid frכm di spεnal kכd εn egzamin am.
• Optical Coherence Tomography (OCT): Dis de egzamin di optik nεv.
• Ilɛktromayografi (EMG): .dis de mכsu di ilektrikal aktiviti fכ di mכsul dεm εn di nεv dεm.
• Blɔd Tɛst: Rul ɔda mɛrɛsin dɛn ɛn chɛk sɔm vaytamɛn lɛvɛl dɛn.
• Evoked Potentials Test: De mכsu di spid we ilektrikal signal dεm de travul tru di nεv dεm.

Aw dɛn kin no se pɔsin gɛt Demyelinating Disease wit MRI?

MRI na tɛst we dɛn kin yuz magnet ɛn redio wev fɔ mek pikchɔ dɛn bɔt yu bren ɛn yu spɛnal kɔd. Dis kin gi yu dɔktɔ bɛtɛ pikchɔ bɔt wetin de apin insay yu bɔdi. If yu gɛt wan sik we de mek yu nɔ ebul fɔ du mami ɛn dadi biznɛs, we yu du MRI skan, i kin sho say dɛn we dɔn pwɛl (we dɛn kɔl lɛsin) na yu bren ɛn yu spɛnal kɔd.

Aw dɛn kin trit Demyelinating Disease?

Di tritmɛnt fɔ demyelinating sik kin difrɛn difrɛn wan bay di kayn sik we yu gɛt . Yu dɔktɔ go wok wit yu fɔ ɛp fɔ kɔntrol yu sayn dɛm ɛn, sɔm tɛm, i go slo fɔ mek di sik skata. Di tritmɛnt we dɛn kin pik kin bi:

• Mɛrɛsin: Drug dɛm wae de ridyus di sik in aktiviti, kɔntrol di sayn dɛm, ɔr chenj di wok we di imyun sistɛm de du.
• Fizik Tɛrapi ɛn Ɔkupeshɔn Tɛrapi: Ɛp wit tin dɛm lɛk wae yu nɔr kin ebul fɔ waka, yu mɔsul dɛm wik, ɛn ɛp yu fɔ du di wok dɛm wae yu kin du ɛvride izi wan.

Yu dɔktɔ go disayd di bɛst tritmɛnt plan bay di sayn dɛm ɛn di kɔndishɔn we yu gɛt. Bifo yu bigin fɔ trit yu, lan bɔt di bad tin dɛn we kin apin to yu ɛn wetin fɔ ɛkspɛkt . If yu gɛt nyu sik ɔ yu de wɔs afta yu dɔn bigin fɔ trit yu, tɛl yu dɔktɔ wantɛm wantɛm. Di kwik we yu bigin fɔ trit yu, na di mɔ yu go gɛt bɛtɛ tin fɔ du.

Wetin na di lukin-grɔn/prɔgnosis fɔ dɛn sik ya?

Di we aw yu de si tin kin difrɛn bad bad wan dipen pan us demyelinating sik de mek yu gɛt di sik. Dɛn sik ya kin afɛkt bɔku tin dɛn na yu layf, lɛk aw yu de tink, muv, ɛn fil. Fɔ ɛgzampul, i nɔ kin izi fɔ yu fɔ waka ɔ fɔ du di wok dɛn we yu de du ɛvride. Sɔm pipul dɛn kin nid ɛp frɔm dɛn fambul fɔ liv na say we sef.

Fɔ sɔm pipul dɛm, di sayn dɛm nɔr kin rili sote ɛn nɔr kin gɛt ɛni ɛfɛkt fɔ lɔng tɛm . Fɔ ɔda pipul dɛn, di sayn dɛn kin rili bad ɛn dɛn kin rili afɛkt dɛn layf ɛvride . Di tin we de apin to ɔlman difrɛn. Nɔr mɛrɛsin nɔr de fɔ dɛn kayn sik ya , bɔt yu dɔktɔ kin ɛp yu fɔ kɔntrol yu sik dɛn ɔl yu layf.

Yu tink se Demyelinating Disease De Chenj di layf we pɔsin kin liv?

Demyelinating Disease kin afɛkt yu layf, bɔt bɔrku sik nɔr kin afɛkt aw lɔng yu go liv . Jɛnɛral wan, sɔm stɔdi dɛn dɔn sho se di layf we pɔsin we gɛt dis maynia sik kin shɔt smɔl fɔ sɔm ia pas pɔsin we nɔ gɛt dis sik. Bɔt dis kin dipen pan aw dɛn dɔn pwɛl yu nɛv sɛl dɛn. I kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Yu dɔktɔ go ebul fɔ ansa dis kwɛstyɔn fayn fayn wan bay di patikyula tin we de apin to yu.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt ɛni wan pan dɛn sayn ya fɔ demyelinating disease, go to dɔktɔ wantɛm wantɛm:

• Vishɔn kin chenj
• Numbness ɔr nɔr de fil fayn
• Wok tranga wan
• Prɔblɛm fɔ pis ɔ fɔ pul dɔti
• I nɔ izi fɔ waka
• Mɔsul dɛn kin stif ɔ wik

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

We yu kam fɔ no se yu gɛt wan sik we de mek yu nɔ gɛt bɛtɛ trɛnk, yu kin gɛt bɔku kwɛstyɔn dɛn. Nɔ shek fɔ aks yu dɔktɔ kwɛstyɔn dɛn lɛk dɛn wan ya:

• Us kayn demyelinating sik a gɛt?
• Dis sik go wɔs (i.e., i go `progres`)?
• Us kayn tritmɛnt yu kin advays?
• Ɛni bad tin de we di tritmɛnt kin du?
• Aw mi prɔgnosis de?

Maylin na wan pat we rili impɔtant na yu bɔdi. I de protɛkt yu nɛv sɛl dɛn ɛn mek dɛn kɔntinyu fɔ wok fayn fayn wan. If i dɔn pwɛl, yu kin gɛt sɔm sayn dɛn lɛk pen, i nɔ kin izi fɔ muv, ɛn i nɔ kin izi fɔ tink gud wan. Dɔktɔ kin no ɛn trit di demyelinating kɔndishɔn we de afɛkt yu. Bikɔs no mɛrɛsin nɔr de fɔ dɛn sik ya, yu go nid fɔ kɔntrol yu sayn dɛm ɔlsay na yu layf wit di ɛp fɔ yu mɛdikal tim. Ɔltɛm tɔk to yu dɔktɔ bɔt yu sik, aw fɔ trit yu, nyu sayn dɛm, ɔr if yu fil se yu sik de wɔs.

Di tin we impɔtant pas ɔl we yu nid fɔ no (Take-Home Message) .

So, Demyelinating Disease na wan kכndyushכn we de apin we di myelin sheath na wi nεv sεstem dεm dεm dεm. Dis kin tan lɛk se yu de mek yu fred, bɔt mɛmba se nɔto yu wangren de. Di sayn dɛm kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin, ɛn na so bak de impak wae de sik kin gɛt kin difrɛn. Di tin we impɔtant pas ɔl na dat, if yu gɛt ɛni wan pan di sayn dɛn we wi dɔn tɔk bɔt na dis atikul, nɔ ignore dɛn ɛn go to dɔktɔ kwik kwik wan. If yu no di sik kwik kwik wan ɛn bigin fɔ trit yu fayn fayn wan, yu kin kɔntrol yu sayn dɛm pasmak ɛn liv nɔrmal, gud layf. Yu dɔktɔ ɛn yu fambul go bi big sɔpɔt pan dis joyn.

` Demyelinating Disease, Myelin, Nεv Sεstem, Mכltipכl Sklεrosis, MS, Simptom dεm, Tritmεnt