Wi ɔl kin fred smɔl we wi si wi mama ɛn papa ɛn ɛlda dɛn de lɔs dɛn mɛmori smɔl smɔl as dɛn de ol. "Dis na di biginin fɔ Alzaima sik?" Di kwɛstyɔn de na di baksay na wi maynd. Te naw, dɛn kin no bɔt Alzaima sik bay wae dɛn de chɛk pɔrsin in mɛmori ɛn luk fɔ sɔm sayn dɛm lɛk wae i de chenj in bihayvya. Bɔt naw, wan grup we sabi bɔt mɛrɛsin na di wɔl dɔn kam wit wan big tin fɔ chenj dis sistɛm. Dɛn se insted fɔ wet fɔ mek di sayn dɛn sho, wi fɔ yuz bayolojikal pruf na wi bɔdi fɔ no dis sik bifo i apin.
Wetin mek dɛn nid dis kayn nyu sistɛm?
Yu kin de tink se, "Wetin mek yu chenj dis sistɛm? Sɔntin de we nɔ fayn wit di sistɛm we de naw?" Fɔ tru, di sistɛm we de naw kin jɔs no di sik afta sɔm damej dɔn de na di bren ɛn di tin dɛn we i kin du dɔn bigin fɔ sho as sayn. Dat min se i dɔn let smɔl fɔ gɛt diagnosis.
Bɔt dis na di men aidia fɔ dis nyu prɔpɔzal.
Dɛn fɔ difayn Alzaima sik bay bayoloji, nɔto bay di sayn dɛm.
Fɔ tɔk am simpul wan, jɔs lɛk aw ditektiv de luk fɔ tin dɛn we go ɛp am bifo dɛn du kraym, di gol na fɔ no di chenj dɛn we de apin na di bɔdi bifo di sayn dɛn we de sho se i gɛt di sik ɛn no se i gɛt di sik. Di rizin fɔ dis na bikɔs, wit di tin dɛn we dɛn dɔn du dis biɛn tɛm pan mɛrɛsin sayɛns, dɛn dɔn mek nyu we dɛn fɔ tɛst we go ebul fɔ no dɛn kayn tin dɛn ya we gɛt layf. Dis kin mek di sik pipul dɛn no bɔt dɛn sik kwik kwik wan, disayd bɔt dɛn layf akɔdin to dat, ɛn go fɛn tritmɛnt we dɛn nid kwik kwik wan. Dɔn bak, sɔmtɛm ɔda sik kin de wae de sho se yu gɛt di sem kayn sik wae de kam wit Alzaima. Tɛnki fɔ dis nyu we, i izi fɔ dɔktɔ dɛn fɔ no kɔrɛkt wan ɛn kwik kwik wan if na rili Alzaima ɔ ɔda sik.
Wetin na dɛn bayomakɛr ya?
We yu yɛri di wɔd " biomarkers ," yu go tink se na big wɔd we kɔmplikt. Bɔt fɔ tru, i rili simpul. Tink bɔt wi bɔdi lɛk motoka. We sɔntin bigin fɔ rɔng wit di motoka in injin, sɔntɛnde wan wɔnin layt kin kam na di dɛshbɔd, nɔto so? Semweso, we sɔntin bigin fɔ rɔng na wi bɔdi, wi kin si sayn dɛn fɔ dat na wi blɔd, wata we de na wi sɛribrospaynal, ɔ ɔda tisu dɛn. Na dat wi kin kɔl bayɔmakɛr.
We i kam pan Alzaima sik, tu men bayɔmarka dɛn de.
1. Beta-amyloid protin dεm: dεn ya de kכmכt na di bren εn fכm sכm sכm sכm kכlכm dεm (plaks).
2. Tau protin dεm: dεn ya de kכmכt insay di nεv sεl dεm na di bren εn fכm tכngl dεm.
te naw, di onli we fכ no kכrekt fכ no if dεn protin dεm ya de na fכ spεshal (εn dia dia) bren skan dεm. Bɔt naw, dɛn dɔn mek nyu blɔd tɛst dɛn we go ebul fɔ no di lɛvɛl dɛn we dɛn prɔtin ya de izi wan. Dis na di big big tin we dɛn dɔn mek fɔ dis prɔpɔzal.
Wan stej sistɛm lɛk di wan we gɛt kansa
Yu go mɔs dɔn yɛri bɔt kansa. Afta dɛn dɔn no se yu gɛt kansa, dɔktɔ dɛn kin sheb am to stej dɛm lɛk "Stage 1" ɛn "Stage 2." Dis kin mek di pɔsin ɛn di wan dɛn we de trit am ɔndastand klia wan aw di sik bad ɛn aw fa i dɔn skata.
Naw, dɛn masta sabi pipul ya de prɔpos fɔ introduks wan sem kayn stej sistɛm fɔ Alzaima sik. akɔdin to dis sistɛm, dɛn kin klas wan sikman insay stej 0 to 6. Dis klasification de bays pan di prɛzɛns ɔf di bayomak dɛm we wi bin dɔn tɔk bɔt, ɛn bak di subtil kɔgnitiv chenj dɛm na mɛmori ɛn bihayvya. Dis go mek di pɔsin ɛn in famili ɔndastand klia wan us stej pan di sik dɛn de.
Aw dis nyu phased sistem de wok?
Dis sistɛm we dɛn dɔn pruv stil de ɔnda diskishɔn, bɔt as i de naw, di klasification of stej dɛm na lɛk dis.
| Stej | Minin ɛn diskripshɔn |
|---|---|
| Stej 0. Di wan we mek | Dɛn pipul ya nɔr gɛt ɛni simptom, nɔr gɛt bayomak, bɔt dɛn gɛt jin dɛm wae de put dɛm pan ay risk fɔ gɛt Alzaima insay di fyuchu (e.g., pipul dɛm wae gɛt Down syndrome). |
| Stej 1. Di wan we mek | Dɛn pipul ya nɔ gɛt ɛni sayn bak . Dɛn mɛmori fayn. Bɔt dɛn kin kam fɔ no se dɛn gɛt bayomak dɛn we gɛt fɔ du wit Alzaima we dɛn de du blɔd tɛst ɔ skan. |
| Stej 2. Di wan we mek | Bayomakɛr dɛn de bak, ɛn bak di mɛmori, di we aw pɔsin de biev, ɛn di we aw i de tink.Chenj dɛn we nɔ kin rili klia dɔn bigin fɔ apin. Dɛn tin ya nɔ kin gɛt big impak pan di tin dɛn we dɛn kin du ɛvride. |
| Stej 3. Di wan we mek | Dis na di sem tin wit wetin wi de kɔl naw "Mild Cognitive Impairment." Di sayn dɛm lɛk wae pɔrsin nɔr de mɛmba fayn kin kam fɔ no mɔr. |
| Stej 4, 5, 6 | Dɛn tri stej ya tan lɛk wae wi kin kɔl naw dis maynia sik wae nɔr kin pasmak, wae nɔr kin pasmak, ɛn wae gɛt siriɔs dis maynia sik. Di sayn dɛm kin klia, ɛn i kin tranga fɔ du di wok dɛm we pɔsin kin du ɛvride. |
Advantej ɛn prɔblɛm dɛn de fɔ dis we fɔ du tin.
Di big bɛnifit fɔ dis nyu we na dat i kin no di sik kwik kwik wan . So, di wan dɛn we de na dis fɔs tɛm kin bɛnifit mɔ frɔm nyu tritmɛnt dɛn.
Bɔt big prɔblɛm de ɛn bɔku agyumɛnt de. Imajin if yu tɛl pɔrsin wae gɛt wɛl bɔdi, wae nɔr de fɔgɛt ɔr gɛt sɔm kayn sik, jɔs bay wae yu luk yu blɔd tɛst rizɔlt ɛn se, "Yu gɛt Alzaima sik wae dɔn bigin," wetin go apin? Aw dat go afɛkt da pɔsin de in maynd, in inshɔrans polisi, ɛn in wok? Dis na sɔntin we ivin sɔm masta sabi bukman dɛn we sabi bɔt mɛrɛsin de aks kwɛstyɔn bɔt. So, if dɛn gi dis kayn sik, i rili impɔtant fɔ gi di pɔsin di rayt advays di sem tɛm. Dɛn stil de agyu bɔt dis bitwin masta sabi bukman dɛn.
Bɔt dis prɔpɔzal de sho se wi de kam fɔ mek big big lip fɔ go bifo pan di diagnosis ɛn tritmɛnt fɔ Alzaima sik.
Mɛsej we dɛn kin kɛr go na os
- Masta sabi bukman dɛn se di we aw dɛn fɔ no bɔt Alzaima sik fɔ bi bay di bayomak dɛn we dɛn kin si na blɔd ɛn skan, pas fɔ bay di sayn dɛn we de sho se pɔsin gɛt am.
- Di men gol fɔ dis na fɔ no di sik bifo di sik sho ɛn gi di chans fɔ trit am kwik kwik wan.
- Lɛk kansa, dɛn dɔn prɔpos fɔ introduks wan stej sistɛm fɔ Alzaima sik frɔm stej 0 to 6.
- Difrɛn opinion stil de bitwin masta sabi pipul dɛm bɔt aw pɔrsin kin ebul fɔ no "Alzheimer's Stage 1" if pɔrsin nɔr gɛt ɛni sayn, bɔt i gɛt bayomak.
- Wae ɔl dɛn tin ya stil de na di prɔpɔzal stej, if dɛn impruv am tumara bambay, dɛn kin mek big difrɛns pan di kia fɔ Alzaima. If yu ɔ pɔsin we de nia yu gɛt prɔblɛm wit yu mɛmori, i impɔtant fɔ tɔk to yu dɔktɔ bɔt dat.
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